For patients with severe arthritis of the ankle, total ankle arthroplasty (TAA) provides better long-term function than ankle arthrodesis (AA), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
New research to be presented this week virtually at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2021 explores the positive and negative effects of lifespan-extending drugs on mitochondrial function and age-related osteoarthritis (OA).
A hand surgeon at Hospital for Special Surgery in New York City performed the first total wrist replacement with an implant he designed. The device, known as KinematX™, received 510(k) clearance from the FDA in 2020.
After a team of researchers showed that a certain enzyme’s presence in cartilage increased significantly in people with osteoarthritis, they targeted it with specially-loaded nanoparticles that stopped the disease’s progression in its tracks.
Dawn Elliott, Blue and Gold Distinguished Professor of Biomedical Engineering at the University of Delaware, has won an $11.8 million grant from the National Institutes of Health to establish the Delaware Center for Musculoskeletal Research -- an NIH-designated Center of Biomedical Research Excellence (COBRE). From tendonitis to osteoarthritis, the center will focus on uncovering what happens at the cellular level when injuries and inflammation occur and will test potential therapeutic interventions.
Tocilizumab, an anti-inflammatory drug used to treat rheumatoid arthritis, improves outcomes in severely ill COVID-19 patients, finds the results of a new trial conducted in hospitals across India — one of the world’s most ethnically diverse countries.
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
In a study released Feb. 22 in JAMA Internal Medicine researchers found that six 20-minute telephone calls over eight weeks coaching participants on how to get better sleep improved their sleep, pain, and daytime function. The improvements in sleep and daytime function persisted 12 months after treatment. One of the lead investigators who has been researching age and sleeping for 40 years offers great tips on getting better sleep. Just because you are aging, does NOT mean your sleep needs to get worse.
The 2021 Kappa Delta Young Investigator Award was presented to Lin Han, PhD, for research on the structure and function of cartilage extracellular matrix (ECM) and its impact on tissue regeneration and disease evolution in osteoarthritis (OA).
The 2021 Kappa Delta Elizabeth Winston Lanier Award was presented to Farshid Guilak, PhD and his co-authors, Bradley T. Estes, PhD, and Franklin T. Moutos, PhD, for their research and development of technology to grow bioartificial cartilage using a patient’s own donor cells and seeding them on a novel scaffold that can be molded to match the shape of a patient’s joint.
The American College of Rheumatology (ACR) has released its COVID-19 Vaccine Clinical Guidance Summary that provides an official recommendation to vaccinate rheumatology patients with musculoskeletal, inflammatory and autoimmune diseases. Important considerations and caveats on how to approach vaccination are included for patients with high disease activity and/or those taking immunosuppressant treatments.
Robotic-assisted knee replacement allows for optimal alignment and positioning of the knee implant, as well as optimal ligament balancing. This is critically important for the best outcome and long-term success of the surgery, according to Geoffrey Westrich, MD, at Hospital for Special Surgery. Such precision could potentially lead to a longer-lasting knee replacement.
Researchers at Washington University School of Medicine in St. Louis have engineered cartilage cells to release an anti-inflammatory drug in response to stresses such cells undergo when they are compressed during weight bearing and movement.
Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm.
For patients undergoing surgery for a hip fracture, there are still unknowns regarding the return to pre-facture level of function, specifically in regard to driving and mobility. However, a new article published in the January issue of the Journal of the American Academy of Orthopaedic Surgeons® (JAAOS®) further quantifies these outcomes. The study authors found that patients can expect to regain full functionality within two to three years after hip fracture surgery. The study also looked at the long-term psychosocial limitations of patients compared to peer groups and concluded that socialization may aid in recovery.
The cumulative incidence of hip dislocation following total hip replacement is about 50 percent higher than suggested by simple analysis of hospital data, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
The final rule provides much-needed increases in Medicare reimbursement for the evaluation and management (E/M) services provided by rheumatologists and other cognitive care specialties to Medicare beneficiaries. Healthcare services billed under E/M codes include examinations, disease diagnosis, risk assessments and care coordination.
The American College of Rheumatology (ACR) today warned that the Centers for Medicare and Medicaid Services (CMS) interim final rule establishing a “most favored nation” (MFN) payment model for Medicare Part B drugs will dramatically disrupt patient access to critical therapies needed to manage rheumatic diseases and conditions.
New evidence-based clinical practice guidelines for the prevention, diagnosis, and treatment of Lyme disease have been developed by a multidisciplinary panel led by the Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology. Representatives from an additional 12 medical specialties and patients also served on the panel.
At this year’s American College of Rheumatology virtual meeting, Hospital for Special Surgery (HSS) presented exciting research related to rheumatology and orthopedic surgery. The research focuses on the diagnosis of renal disorders, the risk of venous thromboembolism after total knee replacement (TKR), and the care of pediatric and young adult patients with rheumatologic diseases. There are also studies related to the care of rheumatology patients during the COVID-19 pandemic.
A study from investigators at Hospital for Special Surgery (HSS) and Brigham and Women’s Hospital in Boston has found that the synovial fluid and blood of people experiencing checkpoint inhibitor-induced arthritis is populated by a type of T cells rarely seen in people with other types of inflammatory arthritis. The findings are being presented at the virtual American College of Rheumatology annual meeting.
Children with arthritis affecting five or more joints, called polyarticular juvenile idiopathic arthritis (polyarticular JIA), living in less affluent families were twice as likely to report more than an hour of morning joint stiffness, compared to their counterparts from more affluent families, according to a study by investigators at Hospital for Special Surgery (HSS). Parents and physicians should be aware that morning joint stiffness may indicate early disease symptoms of polyarticular JIA and serve as a more reliable indicator than pain.
The incidence of dementia in patients with rheumatoid arthritis is lower in patients receiving biologic or targeted synthetic disease modifying antirheumatic drugs (DMARDs) than in patients who receive conventional synthetic DMARDs, according to a new study. The study was presented at the virtual annual meeting of the American College of Rheumatology.
The American College of Rheumatology (ACR) will recognize the recipients of its 2020 Master of the ACR designation and the Awards of Distinction during the College’s Business Meeting & Awards Ceremony. The Distinguished Fellow Award recipients will be honored at the Fellows-in-Training reception.
New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that an artificial intelligence-based analysis model enables accurate detection of definite radiographic sacroiliitis in people with axial spondyloarthritis, an advance that could be useful for both diagnosis in the clinic and classification of patients for inclusion in clinical trials.
A new study shows that patients with rheumatic diseases across Africa, Southeast Asia, the Americas and Europe had trouble filling their prescriptions of antimalarial drugs during the 2020 global coronavirus pandemic, when antimalarials were touted as a possible COVID-19 treatment. Patients who could not access their antimalarial drugs faced worse physical and mental health outcomes as a result. Details of the research was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
New research presented at ACR Convergence, the American College Rheumatology’s annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care.
A new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected experience a mild course of illness. Additionally, fatalities have been low among rheumatic disease patients infected with COVID-19. Details of this research was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, identified key clinical features of chronic nonbacterial osteomyelitis (CNO), which leads to an important step toward the development of much-needed classification criteria for a disease that affects children and young adults worldwide.
Results from a large, international survey shows that only a small fraction of children with rheumatic diseases reported contracting COVID-19. Those who did become infected, all had benign outcomes and did not develop significant complications, despite the fact that most children were taking immunosuppressive medications. The research was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
The American College of Rheumatology (ACR) will preview a new clinical practice guideline for the management of juvenile idiopathic arthritis (JIA) at ACR Convergence, the ACR’s annual meeting. The new recommendations include treatments for systemic JIA, oligoarthritis, TMJ arthritis, and recommendations for medication monitoring and immunizations.
A new study reveals that Black patients with rheumatoid arthritis were less likely to be prescribed a biologic treatment and more likely to use glucocorticoids, which carry a risk of serious long-term side effects. This study highlights ongoing racial disparities in the care of patients with rheumatic disease. Details of the study was shared at ACR Convergence, the American College of Rheumatology’s annual meeting.
New research shows that children with Kawasaki Disease remain at an increased risk for cardiovascular events more than 10 years after hospitalization for their condition, highlighting the need for long-term heart disease surveillance and risk reduction strategies for these young patients. Details of the study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that use of warfarin, a vitamin K drug widely prescribed to prevent blood clots, is associated with a significantly greater risk of knee and hip replacements in patients with osteoarthritis.
A new study presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.
New research shows that corticosteroid injections for knee OA treatment do not hasten a patient’s progression to a total knee replacement when compared with hyaluronic acid injections. Details of this study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, discovers that use of hydroxychloroquine does not cause any significant differences in QTc length or prolonged QTc in people with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).
The American College of Rheumatology (ACR) will preview its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the ACR’s annual meeting. The comprehensive, clinical recommendations for pharmacologic treatment of RA includes important updates to the previous guideline released in 2015.
New research at ACR Convergence, the American College of Rheumatology’s annual meeting, reveals that people of color with rheumatic disease have worse health outcomes from COVID-19 infection, are more likely to be hospitalized to treat their coronavirus infection, and are more likely to require invasive ventilator treatment.