Feature Channels: Autoimmune Diseases

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Released: 6-Apr-2020 12:05 PM EDT
Joslin Research Ties Autoimmunity-Associated Heart Dilation to Potential Heart-Failure Risk in Type 1 Diabetes
Joslin Diabetes Center

There's a higher case fatality rate in type 1 than type 2 diabetes, which suggests different mechanisms for heart failure might be involved in type 1 diabetes.” Given the burden of heart failure in type 1 diabetes, the early identification of patients at particular risk is of importance.

Newswise: Biological ‘atlas’ shows dual personality for immune cells that cause Type 1 diabetes
Released: 30-Mar-2020 4:40 PM EDT
Biological ‘atlas’ shows dual personality for immune cells that cause Type 1 diabetes
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.

Newswise: COVID-19 Tip Sheet: Story Ideas From Johns Hopkins
Released: 24-Mar-2020 9:00 AM EDT
COVID-19 Tip Sheet: Story Ideas From Johns Hopkins
Johns Hopkins Medicine

The following are various story ideas regarding the COVID-19 illness. To interview Johns Hopkins experts on these topics or others, contact JHMedia@jhmi.edu.

Released: 18-Mar-2020 12:05 PM EDT
ACR Releases Position Statement on Prior Authorization
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) has released an official position statement concerning prior authorization for the approval of prescription medications, highlighting the significant burdens it creates for patients and rheumatology professionals. This process can result in a significant delay of care or treatments, treatment abandonment and potential harm to patients.

Released: 26-Feb-2020 4:25 PM EST
Multi-sensor Band Quickly and Simply Records Subtle Changes in Patients with MS
University of California San Diego Health

An international team of scientists, led by UC San Diego researchers, has developed a new, multi-sensor tool that measures subtle changes in multiple sclerosis patients, allowing physicians to more frequently and more quickly respond to changes in symptoms or patient condition.

Newswise: Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
Released: 25-Feb-2020 6:10 PM EST
Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
University of Alabama at Birmingham

Preclinical research shows a pivotal role for cellular metabolism to regulate the fate decision of CD4 T cells as they differentiate into either destructive Th17 cells that mediate chronic inflammation or regulatory Treg T cells, a decision that occurs very early in the activation of CD4 T cells.

11-Feb-2020 12:50 PM EST
New mouse model for celiac disease to speed research on treatments
University of Chicago Medical Center

Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease.

10-Feb-2020 8:00 AM EST
DNA Misfolding in White Blood Cells Increases Risk for Type 1 Diabetes
Perelman School of Medicine at the University of Pennsylvania

Researchers found, in mice, that changes in DNA sequence can trigger the chromosomes to misfold in a way that puts one at a heightened risk for Type 1 diabetes. The study revealed that differences in DNA sequences dramatically changed how the DNA was folded inside the nucleus, ultimately affecting the regulation of genes linked to the development Type 1 diabetes.

Newswise: New Treatment Discovered for Rare Eye Disease May Prevent Blindness
Released: 10-Feb-2020 6:50 AM EST
New Treatment Discovered for Rare Eye Disease May Prevent Blindness
Cedars-Sinai

Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in The New England Journal of Medicine.

Newswise: Half of Lupus Rashes Harbor High Levels of Bacteria Responsible for Infections
Released: 6-Feb-2020 2:30 PM EST
Half of Lupus Rashes Harbor High Levels of Bacteria Responsible for Infections
Michigan Medicine - University of Michigan

A new study finds that one side effect of lupus could also make patients with the autoimmune condition more vulnerable to a skin infection, or spreading the infection to others.


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