Feature Channels: Autoimmune Diseases

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Released: 26-Apr-2021 9:00 AM EDT
Anemia Discovery Points to More Effective Treatment Approaches
University of Virginia Health System

A combination of inexpensive oral medications may be able to treat fatigue-inducing anemias caused by chronic diseases and inflammation, a new discovery from the University of Virginia School of Medicine suggests.

Newswise: Researchers Discover Common Mechanism Causing Autoimmune Disease and Blood Cancers
19-Apr-2021 8:00 AM EDT
Researchers Discover Common Mechanism Causing Autoimmune Disease and Blood Cancers
Yale Cancer Center

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

Released: 31-Mar-2021 9:30 AM EDT
Repurposing Tocilizumab in Scleroderma Patients May Prevent Early Lung Disease
Michigan Medicine - University of Michigan

A phase 3 clinical trial finds an anti-inflammatory drug used in rheumatoid arthritis can preserve lung function in patients with systemic sclerosis.

Released: 26-Mar-2021 10:40 AM EDT
Research Group Identifies Potential Therapeutic Target for Lupus
Michigan Medicine - University of Michigan

Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice.

Released: 19-Mar-2021 9:45 AM EDT
Cancer Immunotherapy May Also Treat Certain Autoimmune Diseases
Michigan Medicine - University of Michigan

The new approach blocks the interaction between cancer cells and immune receptors, showing promise in mice.

Released: 9-Mar-2021 2:05 PM EST
Corrona Announces Name Change to CorEvitas and Expanded Strategic Direction
Corrona, LLC

Corrona, LLC, a leading provider of real-world evidence solutions, announced today that it has changed its name to CorEvitas [kohr-eh'-vi-tahs].

Newswise: LJI research leads to promising combination therapy for type 1 diabetes
Released: 9-Mar-2021 11:40 AM EST
LJI research leads to promising combination therapy for type 1 diabetes
La Jolla Institute for Immunology

Translational research led by scientists at La Jolla Institute for Immunology (LJI) has resulted in a promising combination therapeutic candidate for adults with recent-onset type 1 diabetes.

Newswise:Video Embedded video-should-i-get-the-covid-19-if-i-have-an-autoimmune-disease
VIDEO
Released: 9-Mar-2021 11:20 AM EST
"Video: Should I get the COVID-19 if I have an autoimmune disease?"
American Autoimmune Related Diseases Association (AARDA)

The approval of COVID-19 vaccines has brought with it hope, excitement, as well as concerns. AARDA is committed to ensuring you have the information you need to make the right decisions for your health. A panel of medical experts will discuss frequently asked questions regarding COVID-19 vaccines, as well as address audience questions.

Newswise: March Special Issue of The American Journal of Gastroenterology Focuses on Women’s Health in Gastroenterology and Hepatology
Released: 9-Mar-2021 8:00 AM EST
March Special Issue of The American Journal of Gastroenterology Focuses on Women’s Health in Gastroenterology and Hepatology
American College of Gastroenterology (ACG)

The March issue of The American Journal of Gastroenterology features new clinical research involving sex and gender, including effects of GI and liver conditions on pregnancy, gender disparities in diet and nutrition, Barrett’s esophagus incidence in women with scleroderma, factors influencing whether women pursue advanced endoscopy careers, endoscopy-related musculoskeletal injuries, sex hormone association with increased prevalence of certain types of cancer, and more.

1-Mar-2021 9:40 AM EST
Study Reveals Details of Immune Defense Guidance System
NYU Langone Health

At the beginning of an immune response, a molecule known to mobilize immune cells into the bloodstream, where they home in on infection sites, rapidly shifts position, a new study shows. Researchers say this indirectly amplifies the attack on foreign microbes or the body’s own tissues.

Newswise: Harnessing the Power of Proteins in our Cells to Combat Disease
Released: 25-Feb-2021 12:10 PM EST
Harnessing the Power of Proteins in our Cells to Combat Disease
University of Nevada, Las Vegas (UNLV)

A lab on UNLV’s campus has been a hub of activity in recent years, playing a significant role in a new realm of drug discovery — one that could potentially provide a solution for patients who have run out of options.

Newswise: Distinguishing Between Two Very Similar Pediatric Brain Conditions
Released: 23-Feb-2021 12:00 PM EST
Distinguishing Between Two Very Similar Pediatric Brain Conditions
UT Southwestern Medical Center

Slight differences in clinical features can help physicians distinguish between two rare but similar forms of autoimmune brain inflammation in children, a new study by UT Southwestern scientists suggests. The findings, published online in Pediatric Neurology, could provide patients and their families with a better prognosis and the potential to target treatments specific to each condition in the future.

Released: 22-Feb-2021 12:30 PM EST
Expert Alert: Encephalitis prevention another reason to receive COVID-19 vaccine
Mayo Clinic

Patients with COVID-19 are at risk for neurologic complications, including encephalitis, or inflammation of the brain. "Encephalitis cases have been reported in patients with COVID-19, although on the whole it appears to be a relatively rare complication," says Michel Toledano, M.D., a Mayo Clinic neurologist. In the case of encephalitis caused by communicable diseases for which there is a vaccine available, getting vaccinated is the best way of preventing the disease.

Newswise: Autoimmune Newscast: Should I Get the COVID-19 Vaccine?
Released: 19-Feb-2021 3:35 PM EST
Autoimmune Newscast: Should I Get the COVID-19 Vaccine?
American Autoimmune Related Diseases Association (AARDA)

The approval of COVID-19 vaccines has brought with it hope, excitement, as well as concerns. AARDA is committed to ensuring you have the information you need to make the right decisions for your health. A panel of medical experts will discuss frequently asked questions regarding COVID-19 vaccines, as well as address audience questions during our upcoming Autoimmune Newscast, “Should I Get the COVID-19 Vaccine?” on 2/26 at 2pm ET

15-Feb-2021 9:50 AM EST
Medication Keeps More Patients with ANCA-Associated Vasculitis in Remission Than Steroids
Perelman School of Medicine at the University of Pennsylvania

Avacopan, which targets a receptor that attracts the cells that cause inflammation, was shown to be more effective at keeping patients in remission for a year than prednisone

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Released: 11-Feb-2021 5:15 PM EST
ACR COVID-19 Vaccine Guidance Recommends Vaccination, Addresses Immunosuppressant Drugs & Patient Concerns
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) has released its COVID-19 Vaccine Clinical Guidance Summary that provides an official recommendation to vaccinate rheumatology patients with musculoskeletal, inflammatory and autoimmune diseases. Important considerations and caveats on how to approach vaccination are included for patients with high disease activity and/or those taking immunosuppressant treatments.

Released: 2-Feb-2021 7:00 AM EST
Surgery to Heal Inflamed Gut May Create New Target for Disease
NYU Langone Health

A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.

Released: 28-Jan-2021 1:10 PM EST
Scientists Find Key Function of Molecule in Cells Crucial for Regulating Immunity
University of North Carolina School of Medicine

Scientists discovered that the molecule AIM2 is important for the proper function of regulatory T cells and plays a key role in mitigating autoimmune disease. Treg cells are a seminal population of adaptive immune cells that prevents an overzealous immune responses.

Released: 22-Jan-2021 10:20 AM EST
Cross-Country Research Collaboration Brings First Ever Lupus Estimates
Michigan Medicine - University of Michigan

A meta-analysis of lupus finds the disease is less common than previously thought, but disproportionally affects women and racial and ethnic minorities of both sexes.

18-Jan-2021 9:00 AM EST
Study Pins Down Number of Americans with Most Common Form of Lupus
NYU Langone Health

Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.

Released: 19-Jan-2021 11:35 AM EST
National Research Effort Discovers Relationship Between Inflammation, Metabolism and Scleroderma Scarring
Michigan Medicine - University of Michigan

Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.

Released: 13-Jan-2021 12:30 PM EST
AARDA Announces Leadership Transition
American Autoimmune Related Diseases Association (AARDA)

The American Autoimmune Related Diseases Association announced that Randall Rutta, President and CEO, is leaving to join the National Health Council (NHC) as its CEO, effective February 12, 2021.

Released: 6-Jan-2021 11:05 AM EST
New Research Finds Ginger Counters Certain Autoimmune Diseases in Mice
Michigan Medicine - University of Michigan

The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.

Released: 17-Dec-2020 3:15 PM EST
Protein Linked to Progressive Lung Scarring in Scleroderma Patients
Michigan Medicine - University of Michigan

Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.

Newswise: Targeting T cell protein could prevent type 1 diabetes, study suggests
2-Dec-2020 9:50 AM EST
Targeting T cell protein could prevent type 1 diabetes, study suggests
The Rockefeller University Press

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes. The study, which will be published December 9 in the Journal of Experimental Medicine (JEM), reveals that inhibiting a protein called OCA-B protects mice from type 1 diabetes by limiting the activity of immune cells that would otherwise destroy the pancreas’ insulin-producing β cells.

Released: 17-Nov-2020 9:55 AM EST
Study explores sleep apnea, autoimmune disease link
University of Georgia

New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.

8-Nov-2020 9:00 AM EST
Improving the Diagnosis of Chronic Nonbacterial Osteomyelitis, an Underdiagnosed Chronic Autoinflammatory Syndrome
Hospital for Special Surgery

Researchers have identified several factors that should help improve the diagnosis of chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO). The new study was presented at the virtual annual meeting of the American College of Rheumatology.

Released: 6-Nov-2020 9:00 AM EST
With Close Monitoring Throughout, Safe Pregnancy is Possible for Women with Interstitial Lung Disease
American College of Rheumatology (ACR)

A new study shows that women with interstitial lung disease (ILD) related to autoimmune disease may not need to terminate their pregnancies provided they have close monitoring from their team of multidisciplinary physicians before, during and after pregnancy. Results of the research was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.

Released: 6-Nov-2020 9:00 AM EST
Many with Lupus at High Risk for Adverse Reactions to Pneumocystis Pneumonia Preventive Drug
American College of Rheumatology (ACR)

New research shows that adults with systemic lupus erythematosus, who receive trimethoprim-sulfamethoxazole (TMP-SMX) are at high risk for adverse reactions to the drug, particularly if they are also positive for anti-Smith (anti-Sm) antibodies. Details of the study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.

Released: 6-Nov-2020 9:00 AM EST
Hydroxychloroquine Not Linked to Longer Heart Rhythm Intervals in Rheumatoid Arthritis or Lupus Patients
American College of Rheumatology (ACR)

New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, discovers that use of hydroxychloroquine does not cause any significant differences in QTc length or prolonged QTc in people with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).

2-Nov-2020 12:25 PM EST
A Novel Immunotherapy Proves Effective in Animal Models of Multiple Sclerosis
Thomas Jefferson University

Jefferson researchers develop an approach to specifically impede the autoimmune response that drives the disease, while leaving the rest of the immune system fully functioning.

21-Oct-2020 3:35 PM EDT
New Population of Immune Cells Could Play a Role in Multiple Sclerosis
Thomas Jefferson University

Researchers uncover defining features of a subset of T-cells that may drive autoimmunity in MS, and could prove to be a new target for therapy.

Released: 24-Sep-2020 4:30 PM EDT
Physicians issue warning about rare neurological condition, expected to appear this fall
University of Chicago Medical Center

Pediatricians Henry David, MD, and Madan Kumar, DO, of the University of Chicago Medicine Comer Children's Hospital warn parents of young children to watch out for symptoms of acute flaccid myelitis (AFM), a rare neurological disorder linked to viral infections that can lead to permanent paralysis.

Released: 22-Sep-2020 8:00 AM EDT
MEDIA ALERT: MSVirtual2020
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

The MSVirtual2020 program will continue in an Encore Program that will be held on Saturday, September 26th from 9:00 a.m. – 12:15 p.m. ET. This Encore Program will feature the Late Breaker (9-10:30 a.m. ET) and COVID-19th (10:45 a.m. – 12:15 p.m. ET) sessions.

Newswise: Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis
Released: 21-Sep-2020 1:50 PM EDT
Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis
University of California, Irvine

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

Released: 21-Sep-2020 10:20 AM EDT
American College of Rheumatology Secures $7M Grant to Address Gaps in Lupus Care and Treatment
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) was recently awarded a $7M grant to reduce inequities in symptom recognition, care and disease management of systemic lupus erythematosus (lupus). The grant, which will be led by the ACR’s Collaborative Initiatives (COIN) department, begins on Sept. 30.

Released: 17-Sep-2020 8:05 AM EDT
Children Who Take Prescription Steroids at Increased Risk for Diabetes, High Blood Pressure, Blood Clots
Rutgers University-New Brunswick

Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.

Released: 11-Sep-2020 6:15 PM EDT
Welcome Letter from ACTRIMS President on MSVirtual2020
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

It is with great pleasure that I welcome you to the 8th joint ACTRIMS-ECTRIMS conference. This conference, MSVirtual2020, is the largest conference dedicated to multiple sclerosis (MS) research and our first virtual conference.

Newswise: Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
Released: 9-Sep-2020 3:20 PM EDT
Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
University of Alabama at Birmingham

Inflammatory lipid signaling may provoke the autoimmune disease Type 1 diabetes. Researchers have identified a proinflammatory lipid profile that precedes development of T1D in a mouse model and in children under age 15 who are at high risk for T1D. These lipids may be therapeutic targets.


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