Focus: Cancer Center Featured Story 2

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Newswise: Smilow Cancer Hospital Recognized Among the Nation’s Best for Cancer Care 2023-2024
Released: 2-Aug-2023 2:05 PM EDT
Smilow Cancer Hospital Recognized Among the Nation’s Best for Cancer Care 2023-2024
Yale Cancer Center/Smilow Cancer Hospital

Smilow Cancer Hospital at Yale New Haven is ranked as one of the highest hospitals for cancer care in the country by U.S. News & World Report. This year, Smilow Cancer Hospital at Yale New Haven is listed in the top 50 in the nation and is number 1 in Connecticut. "We are proud to be recognized as one of the leading cancer hospitals in our country,” said Eric Winer, MD, Director of Yale Cancer Center and Physician-in-Chief of Smilow Cancer Hospital.

Released: 2-Aug-2023 12:00 PM EDT
MD Anderson Research Highlights for August 2, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel biomarker that may predict the aggressiveness of pancreatic cancer precursors, insights into the structure and function of a breast and ovarian cancer susceptibility gene, a new approach to overcoming treatment resistance in ovarian cancer, distinguishing features of young-onset rectal cancer, a biomarker and potential target for metastatic lung cancer, machine learning models to better predict outcomes of patients with mantle cell lymphoma (MCL), and a promising therapy for patients with relapsed/refractory MCL.

Released: 1-Aug-2023 5:05 PM EDT
Tip Sheet: Talking about pain with your doctor, the microbiome and graft-vs.-host disease, and RNA’s role in prostate cancer
Fred Hutchinson Cancer Center

Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. Reporting on wildfire smoke? Fred Hutch clinicians and researchers are available to their expertise. Dr. Trang VoPham is an epidemiologist focusing on environmental exposures and risk, follow her on social media.

31-Jul-2023 12:40 PM EDT
Memorial Sloan Kettering Cancer Center Ranked the Best Cancer Center in the Northeast and First in the Nation for Urology Care by U.S. News & World Report
Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center has been recognized as the best cancer center in the northeast, the number two hospital for cancer care in the nation, and the number one hospital nationally for urology care by U.S. News & World Report in its annual Best Hospitals listing.

Released: 1-Aug-2023 12:05 AM EDT
MD Anderson ranked #1 in the nation for cancer care
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today was named number one in the nation for cancer care in U.S. News & World Report’s 2023-24 “Best Hospitals” survey. The institution has been one of the nation’s top two hospitals for cancer care since the survey’s inception in 1990.

Newswise: Researchers develop a new way to classify HPV-associated head and neck cancers
Released: 31-Jul-2023 3:05 PM EDT
Researchers develop a new way to classify HPV-associated head and neck cancers
Yale Cancer Center/Smilow Cancer Hospital

Human papillomavirus (HPV) has been linked to a significant increase in cancers of the throat and tonsils over the past few decades; this is projected to become the most common form of head and neck cancer by 2030. But a major limitation to reducing treatment intensity is the inability to correctly identify the patients whose HPV-related cancers will be the most responsive to treatment.

Newswise: Rutgers Cancer Institute of New Jersey Receives Grants to Support Ongoing Oncology Research
Released: 31-Jul-2023 11:40 AM EDT
Rutgers Cancer Institute of New Jersey Receives Grants to Support Ongoing Oncology Research
Rutgers Cancer Institute of New Jersey

Pilot awards, pre-doctoral fellowship awards and post-doctoral awards totaling $1.5 million were recently awarded to Rutgers Cancer Institute of New Jersey investigators by the New Jersey Commission on Cancer Research (NJCCR).

Released: 28-Jul-2023 3:05 PM EDT
Report on Impact of COVID-19 on Clinical Trials Operations Published in NCI Journal
Association of American Cancer Institutes (AACI)

A report summarizing the results of a series of surveys distributed to AACI cancer center members was published in the Journal of the National Cancer Institute (JNCI) Cancer Spectrum.

Newswise: Yale Scientists Identify Immune Cells Critical for Immunologic Memory for Melanoma
Released: 27-Jul-2023 12:30 PM EDT
Yale Scientists Identify Immune Cells Critical for Immunologic Memory for Melanoma
Yale Cancer Center/Smilow Cancer Hospital

Immune-checkpoint inhibitors have become the standard of care for patients with advanced melanoma to improve survival, but only some patients respond to this immunotherapy and have long-term benefits. The lack of a long-lasting response, researchers say, is related to failure of antitumor immunologic memory. Treatment options for advanced melanoma are limited for patients who do not respond to this type of therapy.

Newswise: Yale Scientists Develop a New Approach to Strengthen CAR-T Cell Therapy
Released: 27-Jul-2023 11:55 AM EDT
Yale Scientists Develop a New Approach to Strengthen CAR-T Cell Therapy
Yale Cancer Center/Smilow Cancer Hospital

Chimeric antigen receptor (CAR)-T cells are a powerful, new form of cancer therapy that are being studied to treat blood cancers. Using a new approach, Yale Cancer Center researchers at Yale School of Medicine found a new way to substantially improve the effectiveness of CAR-T cell therapy. The new study was published in Nature Immunology on July 27.

Newswise: Moffitt Names Paulo Rodriguez, Ph.D., Chair of the Department of Immunology and Co-Leader of the Immuno-Oncology Program
Released: 27-Jul-2023 9:00 AM EDT
Moffitt Names Paulo Rodriguez, Ph.D., Chair of the Department of Immunology and Co-Leader of the Immuno-Oncology Program
Moffitt Cancer Center

Moffitt Cancer Center has appointed Paulo Rodriguez, Ph.D., chair of the Department of Immunology and co-leader of the Immuno-Oncology Program.

26-Jul-2023 12:40 PM EDT
Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance
University of Texas MD Anderson Cancer Center

A new study led by researchers at The University of Texas MD Anderson Cancer Center discovered loss of metabolic fitness in chimeric antigen receptor (CAR) natural killer (NK) cells is a critical mechanism of resistance, with infused cells gradually losing the ability to compete with tumor cells for nutrients, leading to tumor relapse.

Released: 26-Jul-2023 8:00 AM EDT
MD Anderson and Nexo Therapeutics announce strategic research collaboration to advance new therapies against intractable targets
University of Texas MD Anderson Cancer Center

MD Anderson and Nexo announced a strategic research collaboration to rapidly advance new cancer therapies against previously undruggable targets.

Newswise:Video Embedded volunteering-in-late-life-may-protect-the-brain-against-cognitive-decline-and-dementia
VIDEO
Released: 20-Jul-2023 11:10 AM EDT
Volunteering in late life may protect the brain against cognitive decline and dementia
UC Davis Health

Volunteering in late life is associated with better cognitive function — specifically, better executive function and episodic memory, according to a new UC Davis study.

Released: 19-Jul-2023 8:10 PM EDT
NIH renews UC Davis MIND Institute grant to study fragile X-associated syndromes for 24th year
UC Davis MIND Institute

It's fragile X awareness month, and the NIH has renewed funding for a key study of the neurodegenerative condition fragile X-associated tremor ataxia syndrome (FXTAS).

Released: 19-Jul-2023 1:00 PM EDT
Cancer Research Institute Awards Over $28 Million in Grants to Fuel Immunotherapy Innovations
Cancer Research Institute

The Cancer Research Institute awarded $28.7 million in research grants and fellowships in the 2023 fiscal year ending June 30, 2023. In total, CRI distributed 73 awards that will advance cancer immunology research at 41 institutions in 10 countries. CRI grants were awarded to support projects involving a variety of immune-based approaches as well as the development of novel technologies that may help pave the way for the next generation of immunotherapies.

Released: 19-Jul-2023 12:00 PM EDT
MD Anderson Research Highlights for July 19, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 19-Jul-2023 10:20 AM EDT
Breast Cancer Survivors Experience Faster Biological Aging Compared to Cancer-Free Women
Moffitt Cancer Center

A Moffitt Cancer Center researcher, in collaboration with investigators at the National Institutes of Health, are working to answer that question for the nearly 4 million breast cancer survivors in the United States. In their newest study, they found that compared to cancer-free women, breast cancer survivors experience a faster rate of aging.

Newswise: Howard and Susan Elias make $16.25 million gift to fund cancer neuroscience research at MD Anderson
18-Jul-2023 9:00 AM EDT
Howard and Susan Elias make $16.25 million gift to fund cancer neuroscience research at MD Anderson
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today announced a $16.25 million gift from Howard and Susan Elias to accelerate brain tumor and cancer neuroscience research, an emerging field focused on integrating the role of the nervous system in cancer.

Released: 13-Jul-2023 1:05 PM EDT
Fred Hutch invites community to join Obliteride fundraising event on Saturday, Aug. 12
Fred Hutchinson Cancer Center

Thousands of people will come together on Saturday, Aug. 12, in Seattle, Washington, for Obliteride, Fred Hutchinson Cancer Center’s annual bike ride, 5K walk/run and fundraiser.

Newswise: Combination Cancer Therapies Can Shrink Tumors and Improve Survival Outcomes for Patients with Advanced Non-Small Cell Lung Cancer
Released: 13-Jul-2023 11:00 AM EDT
Combination Cancer Therapies Can Shrink Tumors and Improve Survival Outcomes for Patients with Advanced Non-Small Cell Lung Cancer
Yale Cancer Center/Smilow Cancer Hospital

While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in the tumor microenvironment.

Newswise: Fern Lazar of FINN Partners Joins Board of Trustees at the Cancer Research Institute
Released: 12-Jul-2023 8:00 AM EDT
Fern Lazar of FINN Partners Joins Board of Trustees at the Cancer Research Institute
Cancer Research Institute

Fern Lazar, Managing Partner and Global Health Practice Leader at FINN Partners, was elected to the Cancer Research Institute’s Board of Trustees.

Newswise: Brian D. Gonzalez, Ph.D., Named Inaugural Associate Center Director of Research Diversity and Workforce Development
Released: 11-Jul-2023 9:10 AM EDT
Brian D. Gonzalez, Ph.D., Named Inaugural Associate Center Director of Research Diversity and Workforce Development
Moffitt Cancer Center

Moffitt Cancer Center has named Brian D. Gonzalez, Ph.D., as the inaugural associate center director of Research Diversity and Workforce Development. In the new role, Gonzalez will lead efforts to increase diversity among Moffitt’s research faculty, staff and trainees, working in collaboration with the offices of Enterprise Equity; Community Outreach, Engagement & Equity; and Research Education & Training. He will also develop and implement the cancer center’s Plan to Enhance Diversity. This initiative is a new requirement from the National Cancer Institute to show that the workforce of an NCI-designated cancer center reflects the populations of the communities that it serves.

Released: 10-Jul-2023 7:40 PM EDT
Is listening to music better than a sleeping pill?
UC Davis Health

Listening to music reduces the overall severity of insomnia, improves sleep quality and helps to initiate sleep. The effect was comparable to prescription sleep medications, such as the Z-drugs and benzodiazepines.

Newswise: Tumor Monocyte Content Predicts Immunochemotherapy Outcomes for Esophageal Cancer
Released: 10-Jul-2023 11:15 AM EDT
Tumor Monocyte Content Predicts Immunochemotherapy Outcomes for Esophageal Cancer
Ludwig Cancer Research

A Ludwig Cancer Research study has discovered that the presence of relatively high numbers of immune cells known as monocytes in tumors is linked to better outcomes in esophageal cancer patients treated with a combination of chemotherapy and immunotherapy, or immunochemotherapy.

Released: 7-Jul-2023 4:40 PM EDT
Tip Sheet: Understanding cancer-related pain, newborn screening for deadly immune disorder — and new Fred Hutch leadership
Fred Hutchinson Cancer Center

Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. If you’re looking for resources who can comment on skin cancer awareness and skin protection during the summer months, see our list of experts and reach out to [email protected] to set up interviews.

Newswise: 10 Quick Facts about Sarcoma, one of the Rarest Cancers
Released: 7-Jul-2023 2:20 PM EDT
10 Quick Facts about Sarcoma, one of the Rarest Cancers
Rutgers Cancer Institute of New Jersey

Sarcoma can be a difficult disease to detect and is often called ‘the forgotten cancer,’ that can grow in connective tissue like bones, nerves, muscles, tendons, cartilage and blood vessels of the arms and legs. It causes abdominal pain, lump, bone pain, and weight loss, and makes up approximately 1 percent of all adult cancer diagnoses. Understanding more about this disease can help people to identify it early. Learn more about Sarcoma in this blog.

Newswise: Eliminating Extra Chromosomes in Cancer Cells Prevent Tumor Growth
Released: 6-Jul-2023 3:05 PM EDT
Eliminating Extra Chromosomes in Cancer Cells Prevent Tumor Growth
Yale Cancer Center/Smilow Cancer Hospital

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively targeting extra chromosomes may offer a new route for treating cancer. The study was published July 6 in the journal Science.

Newswise: New single-cell study provides novel insights into gastric cancer
6-Jul-2023 10:40 AM EDT
New single-cell study provides novel insights into gastric cancer
University of Texas MD Anderson Cancer Center

A single-cell study led by MD Anderson researchers and published in Cancer Cell provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

Newswise: First New Jersey Patient Treated with Genetically Modified T-Cells Developed at state’s only National Cancer Institute-designated Comprehensive Cancer Center
Released: 5-Jul-2023 12:45 PM EDT
First New Jersey Patient Treated with Genetically Modified T-Cells Developed at state’s only National Cancer Institute-designated Comprehensive Cancer Center
Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey has treated its first patient using genetically modified T-cells that were manufactured in its own state-of-the-art Good Manufacturing Practices (GMP) facility.

Released: 5-Jul-2023 9:30 AM EDT
Moffitt Investigates Association between Inflammation and Treatment Related Symptoms in Gynecologic Cancers
Moffitt Cancer Center

Moffitt Cancer Center researchers having been investigating what may trigger treatment related symptoms in patients with gynecologic cancers. In a new study published in the journal Cancers, they evaluated the relationship between inflammatory biomarkers and self-reported treatment related symptoms among this patient population.

Newswise: Pancreatic Cancer Risk Lower if Pancreatic Cysts Remain Stable for Five Years
Released: 29-Jun-2023 4:05 PM EDT
Pancreatic Cancer Risk Lower if Pancreatic Cysts Remain Stable for Five Years
Yale Cancer Center/Smilow Cancer Hospital

Low-risk branch duct intraductal papillary mucinous neoplasms (IPMN) are the most common precancerous form of mucinous pancreatic cysts and once identified require regular surveillance imaging. But consensus is still forming around how long that watchful period should last.

27-Jun-2023 4:00 PM EDT
Blood test aids in predicting lung cancer mortality risk
University of Texas MD Anderson Cancer Center

A blood-based four-protein panel (4MP), when combined with a lung cancer risk model (PLCOm2012), can better identify those at high risk of dying from lung cancer than the current U.S. Preventive Services Task Force (USPSTF) criteria.

Newswise: Highlighting Women Scientists: Rutgers Cancer Institute Researcher Awarded V Foundation for Cancer Research Grant
Released: 28-Jun-2023 3:05 PM EDT
Highlighting Women Scientists: Rutgers Cancer Institute Researcher Awarded V Foundation for Cancer Research Grant
Rutgers Cancer Institute of New Jersey

Christina Glytsou, PhD, member of the Cancer Metabolism and Immunology Cancer Pharmacology Program at Rutgers Cancer Institute of New Jersey, has received an award from The V Foundation for Cancer Research, a premier cancer research charity, to support her research on mitochondrial dynamics adaptations in drug-resistant acute myeloid leukemia.

Newswise: Largest-ever atlas of normal breast cells brings unprecedented insights into mammary biology
26-Jun-2023 4:05 PM EDT
Largest-ever atlas of normal breast cells brings unprecedented insights into mammary biology
University of Texas MD Anderson Cancer Center

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world’s largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer. The Human Breast Cell Atlas, published today in Nature, used single-cell and spatial genomic methods to profile more than 714,000 cells from 126 women. The breast atlas highlights 12 major cell types and 58 biological cell states, and identifies differences based on ethnicity, age and the menopause status of healthy women.

Newswise: KU Cancer Center receives historic $100 million gift from Sunderland Foundation to support new cancer research and care facility
Released: 27-Jun-2023 9:05 PM EDT
KU Cancer Center receives historic $100 million gift from Sunderland Foundation to support new cancer research and care facility
University of Kansas Cancer Center

The University of Kansas Cancer Center has received a $100 million lead gift to build a new, state-of-the-art destination cancer center. This gift is both the largest gift ever given by the Sunderland Foundation and the largest ever received by the University of Kansas and The University of Kansas Health System.

Released: 27-Jun-2023 3:00 PM EDT
MD Anderson Research Highlights for June 27, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

   
Newswise: New understanding of why kidney cancers become metastatic discovered by MD Anderson researchers
25-Jun-2023 11:00 AM EDT
New understanding of why kidney cancers become metastatic discovered by MD Anderson researchers
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression. The study, published today in Nature Cancer, demonstrates that the loss of a cluster of interferon receptor (IFNR) genes plays a pivotal role in allowing cancer cells to become tolerant of chromosomal instability. This genomic feature may be used to help clinicians predict a tumor’s potential to become metastatic and treatment resistant.

Newswise: Study hints at how cancer immunotherapy can be safer
Released: 23-Jun-2023 9:25 AM EDT
Study hints at how cancer immunotherapy can be safer
Yale Cancer Center/Smilow Cancer Hospital

Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. Immunotherapies that block checkpoint receptors like PD-1, proteins that limit the capacity of T cells to attack tumors, have become the choice for the treatment of numerous types of solid cancer.

Newswise: MD Anderson and Ochsner Health announce partnership to create first fully integrated cancer program in Louisiana
Released: 22-Jun-2023 12:30 PM EDT
MD Anderson and Ochsner Health announce partnership to create first fully integrated cancer program in Louisiana
University of Texas MD Anderson Cancer Center

MD Anderson and Ochsner Health announced a partnership to create Ochsner MD Anderson Cancer Center in southeastern Louisiana. Cancer patients in the region now have access to cancer treatments that are among the most advanced in the nation.

Newswise: Bringing the Power Of
Released: 22-Jun-2023 11:45 AM EDT
Bringing the Power Of "Multiplex" Imaging to Clinical Pathology
Ludwig Cancer Research

Researchers at the Ludwig Center at Harvard have developed a platform technology for imaging that enables integration of the methods of microscopic analysis long employed in pathology laboratories with the visualization of multiple molecular markers in individual cells that is now rapidly advancing in research labs.

   
Released: 22-Jun-2023 11:35 AM EDT
Youthful Energy
University of New Mexico Comprehensive Cancer Center

The University of New Mexico Comprehensive Cancer Center is using the feedback it gets from young adult cancer survivors to craft a support group that fits their needs.

Released: 21-Jun-2023 4:05 PM EDT
Not So Hard to Reach
University of New Mexico Comprehensive Cancer Center

When Prajakta Adsul, MBBS, PhD, MPH, at the UNM Comprehensive Cancer Center, learned about LGBTQIA+ communities in New Mexico, she became inspired to start filling the void of information about cancer screening and survivorship in these populations. Using a novel survey, she and her team collected information from 2,500 individuals; it's the largest volume of data of its kind.

Newswise: Mutant KRAS regulates Y chromosome gene in colorectal cancer, driving metastasis and inhibiting anti-tumor immunity
20-Jun-2023 2:05 PM EDT
Mutant KRAS regulates Y chromosome gene in colorectal cancer, driving metastasis and inhibiting anti-tumor immunity
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a gene on the Y chromosome that is upregulated in KRAS-mutated colorectal cancer (CRC), increasing tumor cell invasiveness and reducing anti-tumor immunity in male patients.

Newswise: Adagrasib effective for patients with KRAS G12C-mutant lung cancer and untreated brain metastases
15-Jun-2023 4:00 PM EDT
Adagrasib effective for patients with KRAS G12C-mutant lung cancer and untreated brain metastases
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center found the KRAS G12C inhibitor adagrasib showed promising activity suppressing cancer growth not only within the lungs but also in brain metastases for patients with KRAS G12C-mutated non-small cell lung cancer.

15-Jun-2023 2:20 PM EDT
Patients with refractory metastatic colorectal cancer experience survival benefits with fruquintinib
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer. Findings from the global FRESCO-2 trial, published today in The Lancet, were first presented at the European Society for Medical Oncology (ESMO) Congress 2022.

Newswise: NCCN Convenes Policy Summit Assessing Impact of Geography on Cancer Outcomes, Examining Rural and Urban Divide
Released: 15-Jun-2023 2:00 PM EDT
NCCN Convenes Policy Summit Assessing Impact of Geography on Cancer Outcomes, Examining Rural and Urban Divide
National Comprehensive Cancer Network® (NCCN®)

Today, the National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—convened a policy summit to examine how geography impacts cancer outcomes.



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