RUDN University chemists have proposed the way to construct secondary amines — organic compounds that are widely used in all fields of chemistry. The reaction allows to obtain a product with 97% yield. It goes in visible light and does not require auxiliary reagents.
Bitter taste receptors do not only support humans in tasting. They are also found on cancer cells. A team led by Veronika Somoza from the Faculty of Chemistry at the University of Vienna and the German Leibniz Institute for Food Systems Biology at the Technical University of Munich has investigated the role they play there. For this purpose, the scientists compiled and evaluated extensive scientific data. Their results suggest that bitter taste receptors should also be considered as additional targets for chemotherapeutic agents in the future and should be investigated in this regard. The systematic review recently appeared in the journal Cancers.
Advanced cell-based therapies are providing groundbreaking treatment options when other drugs aren’t working. Georgia Tech researchers have developed tool the size of a thumbnail that performs real-time cell analysis, improving efficiency and speeding up the time it takes to create a personalized, life-saving treatment and cures for previously untreatable diseases.
Scientists know that ethylene comes from microbes, but the only known natural microbial processes that produce ethylene require oxygen. But now a team of scientists have discovered an enzyme system from bacteria called methylthio-alkane reductases that work without oxygen, instead scavenging sulfur to produce ethylene, ethane, or methane as a byproduct. The research may have applications in biofuels.
Beronda Montgomery will present the Mentoring Keynote at Cell Bio Virtual 2021 on December 1 at 12:15 PM EST. Montgomery is the Michigan State University Foundation Professor and Assistant Vice President for Research & Innovation at Michigan State University (MSU). She is a member of the faculty of the MSU Departments of Biochemistry & Molecular Biology and Microbiology & Molecular Genetics.
Developed by scientists from Oak Ridge National Laboratory and Idaho National Laboratory in the Department of Energy’s Critical Materials Institute, the technology provides insight into how to cost-effectively separate in-demand rare-earth elements.
Chula Pharmaceutical Science helps increase public confidence to keep COVID-19 at bay with their new test kit to verify the safety and efficacy of hand sanitizers and alcohol-based gel and spray products.
To find the right battery molecules, researchers at the U.S. Department of Energy’s (DOE) Argonne National Laboratory have turned to the power of artificial intelligence to search through a vast chemical space of over a million molecules and optimize for several properties.
A team of researchers from the U.S. National Science Foundation Center for Sustainable Polymers based at the University of Minnesota Twin Cities have developed a chemical technology of combined fermentation and chemical refining that can produce petroleum-like liquids from renewable plants. These renewable liquids could serve as a more sustainable replacement for today’s fossil fuels used to make everyday products like plastic containers and bags, automobile parts, lubricants, and soaps.
Researchers report in ACS’ Environmental Science & Technology Letters that satellite data from before & during the spring 2020 lockdown in Los Angeles shows that vehicles are the main source of urban airborne ammonia, which forms small particles that contribute to air pollution & harm human health.
In May 2021, the Centers for Disease Control officially recognized that SARS-CoV-2 is airborne. Now UC San Diego Professor Rommie Amaro has modeled the delta virus inside an aerosol for the first time.
With multiple clinical trials under way, it’s likely both a drug using Ac-225 and increased demand for the radioisotope are in the near future — and the U.S. Department of Energy wants to be ready. Since 2015, DOE’s Isotope Program has sponsored the Tri-Lab Effort to Provide Accelerator-produced Ac-225 for Radiotherapy. Thorium-232 targets are irradiated in proton accelerators at Los Alamos and Brookhaven national laboratories, then sent to ORNL for processing in hot cells dedicated to alpha radiation. The purpose: producing bigger batches, faster. In June, ORNL processed the largest batch of Ac-225 ever put in inventory.
For years, researchers believed that the smaller the domain size in a ferroelectric crystal, the greater the piezoelectric properties of the material. However, recent findings by Penn State researchers have raised questions about this standard rule.
An international team of researchers from the University of Minnesota Twin Cities and Kiel University in Germany have discovered a path that could lead to shape-shifting ceramic materials. This discovery could improve everything from medical devices to electronics.
A team used machine-learned descriptions of interatomic interactions on the 200-petaflop Summit supercomputer at Oak Ridge National Laboratory to model more than a billion carbon atoms at quantum accuracy and observe how diamonds behave under extreme pressures and temperatures.
Researchers report in ACS Infectious Diseases that they have identified compounds that tackle fungal resistance in a new way — by interfering with fungal enzymes required for fatty acid synthesis — potentially opening the door to better therapies.
Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have come up with a naturally derived wild strawberry aroma by having an edible fungus make it from waste from black currant juice production.
UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study, published in Science, identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights into the ways pairs or groups of proteins fit together to carry out cellular processes could lead to a wealth of new drug targets.
Binghamton University Chemistry Professor Eriks Rozners has received a two-year $428,330 grant from the National Institute of Allergy and Infectious Diseases for a research project which explores the "switch" behind the coronavirus.
UNLV geochemists have discovered a new mineral on the surface of the Earth. Coined "davemaoite" and entrapped in a diamond, the mineral traveled from a depth of at least 410 miles deep within the Earth's lower mantle.
A new study featured in Proceedings of the National Academy of Sciences offers a potential alternate approach that combines pressure and electrochemistry to stabilize superhydrides at moderate, perhaps even close to ordinary, pressures.
Using neutron experiments at Oak Ridge National Laboratory, a research team led by Vanderbilt University successfully captured the most detailed view to date of water’s hydrogen bonding patterns around DNA, opening new possibilities for studying how water impacts DNA function.
UPTON, NY -- Chemists have been searching for efficient catalysts to convert methane -- a major component of abundant natural gas -- into methanol, an easily transported liquid fuel and building block for making other valuable chemicals. Adding water to the reaction can address certain challenges, but it also complicates the process.
UC San Diego scientists have created a new technology that rapidly detects the SARS-CoV-2 virus. The new SENSR was developed using CRISPR gene-editing technology as a rapid diagnostic that could eventually be used in homes, airports and other locations.
Tackling pollution from the emission of nitrogen compounds, particularly ammonia, could reduce many of the 23.3 million years of life that were lost prematurely across the world in 2013 due to nitrogen-related air pollution.
Wetlands are natural climate change buffers since they act as carbon “sinks." Better understanding how wetland sediments work could inform how they will function with more frequent rainstorms. Georgia Tech will develop a new model to predict where and when sediment disruptions are most likely to occur.
Researchers reporting in ACS Central Science developed a method for imaging lithium in living cells, allowing them to discover that neurons from bipolar disorder patients accumulate higher levels of lithium than healthy controls.
A team of biologists and engineers modified a microbe so that it can produce a biofuel using only three renewable and naturally abundant source ingredients: carbon dioxide, solar panel-generated electricity and light.
The Association for Molecular Pathology (AMP), the premier global, molecular diagnostics professional society, today announced the recipients of this year’s Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award.
Three studies found that a group of chemicals found in many plastic products are harmful to women who are pregnant and to couples planning a pregnancy – yet the products are often not on the list of things to be avoided.
Proteins bind together through a complex mix of chemical interactions. What if some proteins bind due to their shapes, a much simpler process? Researchers used the Summit supercomputer to model a type of interaction that requires proteins to chemically “fit” precisely. The team found that among a sample of 46 protein pairs that bind to one another, 6 often assembled based on their shapes.
Researchers have found the two-year heatwave known as ‘the Blob’ may have temporarily dampened the Pacific’s ‘biological pump,’ which shuttles carbon from the surface ocean to the deep sea where it can be stored for millennia.
Two PNNL interns are behind recent innovation in real-time testing and continuous monitoring for pH and the concentration of chemicals of interest in chemical solutions; outcomes have applicability not only to nuclear, but to industries.
A multidisciplinary team of researchers at Wayne State University have been awarded a $3.1 million grant from the U.S. Army Corps of Engineers ERDC program to seek alternative sources of rare earth elements critical to advanced military and consumer technologies.