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Newswise: Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization

Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization

University of Alabama at Birmingham

The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells.

Channels: All Journal News, Diabetes, National Institutes of Health (NIH), Grant Funded News,

Released:
21-Feb-2020 3:05 PM EST
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Bariatric surgery effective against early-onset obesity too

University of Gothenburg

Surgical treatment of obesity is as effective for individuals who developed the disorder early, by the age of 20, as for those who have developed obesity later in life, a study from the University of Gothenburg shows.

Channels: All Journal News, Diabetes, Obesity, Surgery, Weight Loss, Staff Picks,

Released:
21-Feb-2020 11:55 AM EST
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Research Results

Patients frequently refuse insulin therapy, delaying blood sugar control

Brigham and Women’s Hospital

Patients with type 2 diabetes who have high levels of blood sugar are at greater risk of serious complications such as chronic kidney disease, heart disease and blindness.

Channels: All Journal News, Diabetes, Healthcare, Public Health,

Released:
20-Feb-2020 1:10 PM EST
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Research Results
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  • Embargo expired:
    19-Feb-2020 9:00 AM EST

The potentially deadly paradox of diabetes management

Mayo Clinic

Diabetes affects nearly 1 in 10 adults in the U.S., of these millions, more than 90% have Type 2 diabetes. Controlling blood sugar and glycosylated hemoglobin levels ― or HbA1c, which is sometimes referred to as A1C ― is key to diabetes management and necessary to prevent its immediate and long-term complications. However, new Mayo Clinic research shows that diabetes management may be dangerously misaligned.

Channels: All Journal News, Diabetes, Healthcare, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK),

Released:
17-Feb-2020 6:10 PM EST
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Comer Children’s and the Kovler Diabetes Center lead the way in monogenic diabetes care, research

University of Chicago Medical Center

Researchers at the University of Chicago Medicine are leading the charge to educate clinicians and families about monogenic diabetes, a rare and frequently misdiagnosed subset of the disease.

Channels: All Journal News, Diabetes, Genetics, Obesity,

Released:
13-Feb-2020 5:55 PM EST
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Research Results
  • Embargo expired:
    12-Feb-2020 2:05 PM EST

Mount Sinai Discovers New Drug Combo to Induce High Rates of Human Beta Cell Regeneration

Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells—the cells in the pancreas that produce insulin—without harming most other cells in the body. The result is an important step toward a diabetes treatment that restores the body’s ability to produce insulin.

Channels: Pharmaceuticals, Regenerative Medicine, National Institutes of Health (NIH), All Journal News, Diabetes,

Released:
9-Feb-2020 7:05 PM EST
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  • Embargo expired:
    11-Feb-2020 11:00 AM EST

DNA Misfolding in White Blood Cells Increases Risk for Type 1 Diabetes

Perelman School of Medicine at the University of Pennsylvania

Researchers found, in mice, that changes in DNA sequence can trigger the chromosomes to misfold in a way that puts one at a heightened risk for Type 1 diabetes. The study revealed that differences in DNA sequences dramatically changed how the DNA was folded inside the nucleus, ultimately affecting the regulation of genes linked to the development Type 1 diabetes.

Channels: All Journal News, Autoimmune Diseases, Diabetes, Genetics, National Institutes of Health (NIH), Grant Funded News,

Released:
10-Feb-2020 8:00 AM EST
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Research Results
  • Embargo expired:
    11-Feb-2020 6:00 AM EST
Released:
10-Feb-2020 1:35 PM EST
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Research Results
Newswise: University Hospitals Ahuja Medical Center Physician First in Ohio to Use Wound Care Imaging Device in Clinical Setting

University Hospitals Ahuja Medical Center Physician First in Ohio to Use Wound Care Imaging Device in Clinical Setting

University Hospitals Cleveland Medical Center

University Hospitals Ahuja Medical Center (UH) is the first clinical setting in Ohio using special technology to identify harmful bacteria, leading to healing for patients suffering from chronic wounds. Windy Cole, DPM, Medical Director of the UH Ahuja Wound Care Center, conducted research studies utilizing the MolecuLight i:X® and is leading the use of the novel device in the state.

Channels: All Journal News, Diabetes, Pain, Technology,

Released:
10-Feb-2020 10:25 AM EST
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