Feature Channels: Epilepsy

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Newswise: Pickled capers activate proteins important for human brain and heart health
Released: 13-Jul-2020 12:05 PM EDT
Pickled capers activate proteins important for human brain and heart health
University of California, Irvine

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

Newswise: Can community-based interventions help to close the epilepsy treatment gap?
Released: 1-Jul-2020 2:55 PM EDT
Can community-based interventions help to close the epilepsy treatment gap?
International League Against Epilepsy

More than 50 million people have epilepsy; about 80% live in lower- or middle-income countries, where diagnosis and treatment can be difficult or impossible. The percentage of people with epilepsy that is not receiving treatment is known as the treatment gap; in some countries, this gap exceeds 90%.

Newswise: Suspended studies and virtual lab meetings: How the COVID-19 pandemic is affecting epilepsy researchers
Released: 1-Jul-2020 10:10 AM EDT
Suspended studies and virtual lab meetings: How the COVID-19 pandemic is affecting epilepsy researchers
International League Against Epilepsy

How was epilepsy research forced to morph during the first few months of the COVID-19 pandemic? Researchers from 11 countries shared their experiences and thoughts on the future of laboratory research, clinical trials, and in-person conferences.

Newswise: A deeper dive into epilepsy: Integrating tools for characterizing focal cortical dysplasia
Released: 24-Jun-2020 6:45 PM EDT
A deeper dive into epilepsy: Integrating tools for characterizing focal cortical dysplasia
International League Against Epilepsy

Journal Prize winner Zhong Ying integrated genetics, clinical presentation, EEG, MRI, and histopathological diagnosis in a group of people with drug-resistant epilepsy. All had a specific type of brain lesion that can be difficult to identify.

Newswise: Bridging the information gap with new EEG techniques for epilepsy
Released: 24-Jun-2020 6:40 PM EDT
Bridging the information gap with new EEG techniques for epilepsy
International League Against Epilepsy

Journal Prize winner Ana Coito is developing methods to extract information from EEG readings about brain connectivity and information exchange. Her award-winning research focused on applying these methods to low-density EEG readings, which would make them accessible to more regions of the world.

Newswise: Harnessing complexity to advance epilepsy research: Learning the language of EEG spike-wave discharges
Released: 24-Jun-2020 6:40 PM EDT
Harnessing complexity to advance epilepsy research: Learning the language of EEG spike-wave discharges
International League Against Epilepsy

Journal Prize winner Jesse A. Pfammatter found that certain EEG patterns that indicate absence epilepsy may hold more information than previously thought.

Newswise: Improving treatment for psychogenic seizures: “This is a group of patients that we are taking less seriously”
Released: 23-Jun-2020 2:45 PM EDT
Improving treatment for psychogenic seizures: “This is a group of patients that we are taking less seriously”
International League Against Epilepsy

Journal prize winner Benjamin Tolchin tested motivational interviewing to help people with psychogenic non-epileptic seizures (PNES) start and continue psychotherapy. Often mistaken for epilepsy, these seizures cause serious problems, yet many health care professionals discount them as "not real."

Newswise: From bench to beach: Award-winning epilepsy researcher furthers understanding of how cannabidiol stops seizures
Released: 23-Jun-2020 1:55 PM EDT
From bench to beach: Award-winning epilepsy researcher furthers understanding of how cannabidiol stops seizures
International League Against Epilepsy

Lyndsey Anderson traveled halfway around the world to do epilepsy research in Sydney, Australia. Recently, she was awarded ILAE's 2020 Epilepsia Prize for Basic Science Research.

Newswise: New Imaging Method Tracks Brain’s Elusive Networks
Released: 10-Jun-2020 3:35 PM EDT
New Imaging Method Tracks Brain’s Elusive Networks
National Institute of Biomedical Imaging and Bioengineering

Understanding the source and network of signals as the brain functions is a central goal of brain research. Now, Carnegie Mellon engineers have created a system for high-density EEG imaging of the origin and path of normal and abnormal brain signals.

Newswise: When seizures don't stop: What's the latest in treating status epilepticus?
Released: 26-May-2020 2:50 PM EDT
When seizures don't stop: What's the latest in treating status epilepticus?
International League Against Epilepsy

When seizures last longer than about 5 minutes--a condition called status epilepticus--emergency treatment is required. About two-thirds of people respond to initial treatment with benzodiazepines, but the others need a second drug. Which drug to choose is a matter of some debate.

Newswise: New wearable devices set to diagnose medical conditions such as preeclampsia, epilepsy and heart attacks
Released: 21-May-2020 7:05 PM EDT
New wearable devices set to diagnose medical conditions such as preeclampsia, epilepsy and heart attacks
University of South Australia

Transforming how common health conditions are diagnosed using point-of-care and wearable bio diagnostic devices is the goal of a new $2.2 million University of South Australia project.

19-May-2020 11:05 AM EDT
Blood Test May Help Predict Whose MS Will Get Worse
American Academy of Neurology (AAN)

A blood test may help predict which people with multiple sclerosis (MS) will get worse during the following year, according to a study published in the May 20, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Newswise:Video Embedded a-sound-treatment
VIDEO
20-May-2020 2:00 PM EDT
A sound treatment
University of Utah

University of Utah biomedical engineering assistant professor Jan Kubanek has discovered that sound waves of high frequency (ultrasound) can be emitted into a patient’s brain to alter his or her state. It’s a non-invasive treatment that doesn’t involve medications or surgery and has a unique potential to treat mental disorders including depression and anxiety and neurological disorders such as chronic pain and epilepsy.

Newswise: Scientists and neurosurgeon team up to develop novel imaging device for babies with brain disorders
Released: 6-May-2020 10:10 AM EDT
Scientists and neurosurgeon team up to develop novel imaging device for babies with brain disorders
University of Texas Health Science Center at Houston

Using night-vision goggle technology, near-infrared light, and high-resolution detectors, a wearable imaging device for awake infants with brain disorders was developed by a team of scientists and a pediatric neurosurgeon at UTHealth. Cap-based Transcranial Optical Tomography (CTOT), which utilizes a cap for the baby’s head, is the first high-resolution, whole-brain functional imaging device that does not require the baby to be put under anesthesia.

Newswise: Two Steps Closer to Flexible, Powerful, Fast Bioelectronic Devices
23-Apr-2020 1:55 PM EDT
Two Steps Closer to Flexible, Powerful, Fast Bioelectronic Devices
Columbia University School of Engineering and Applied Science

Led by Biomedical Engineering Prof Dion Khodagholy, researchers have designed biocompatible ion-driven soft transistors that can perform real-time neurologically relevant computation and a mixed-conducting particulate composite that allows creation of electronic components out of a single material. These have promise for bioelectronic devices that are fast, sensitive, biocompatible, soft, and flexible, with long-term stability in physiological environments such as the human body. In particular, they could facilitate diagnosis and monitoring of neurological disease.

Newswise: In epilepsy, seizures are often frightening. What happens afterward can be worse.
Released: 13-Apr-2020 8:55 AM EDT
In epilepsy, seizures are often frightening. What happens afterward can be worse.
International League Against Epilepsy

Seizure control is the primary driver of epilepsy treatment. For many people with epilepsy, however, the seizures themselves are secondary to what comes after: fatigue, memory loss and other issues that dramatically affect their lives.

Newswise: Post-Ictal Psychosis: A Medical Emergency for People with Epilepsy
Released: 12-Apr-2020 3:05 PM EDT
Post-Ictal Psychosis: A Medical Emergency for People with Epilepsy
International League Against Epilepsy

About 70% of people with epilepsy report post-seizure (post-ictal) complications, ranging from fatigue to memory issues to headache. Post-ictal psychosis while rare, is perhaps the most dramatic of these. As many as 7% of people with temporal lobe epilepsy develop PIP, which can cause suicidal behavior or interpersonal violence. The condition requires immediate attention and treatment.

Newswise: Hold the phone: Smartphone video makes it easier to diagnose epilepsy and psychogenic seizures
Released: 4-Mar-2020 1:40 PM EST
Hold the phone: Smartphone video makes it easier to diagnose epilepsy and psychogenic seizures
International League Against Epilepsy

What if there was a tool to help with faster, more accurate diagnosis of both psychogenic seizures and epilepsy? And what if this tool was simpler and less expensive than video EEG, and available almost everywhere?

24-Feb-2020 10:35 AM EST
Study Finds Artisanal CBD Not as Effective as Pharmaceutical CBD for Reducing Seizures
American Academy of Neurology (AAN)

Children and teens with epilepsy who were treated with pharmaceutical cannabidiol (CBD) had much better seizure control than those who were treated with artisanal CBD, according to a preliminary study to be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto, Canada, April 25 to May 1, 2020.

Newswise: Reducing the epilepsy treatment gap in Pakistan: Start small, stay flexible, never give up
Released: 17-Feb-2020 11:55 AM EST
Reducing the epilepsy treatment gap in Pakistan: Start small, stay flexible, never give up
International League Against Epilepsy

In retrospect, Pakistan's effort to reduce the treatment gap can appear painstakingly planned, like the blueprints for a shopping complex or a neighborhood. But the secret of the country's success is not rooted in elaborate planning. Nor did it rely on generous funding or government support.

Newswise: Epilepsy education at Disneyland: Spreading awareness, changing lives
Released: 6-Feb-2020 8:55 AM EST
Epilepsy education at Disneyland: Spreading awareness, changing lives
International League Against Epilepsy

At Epilepsy Awareness Day at Disneyland, thousands of families and physicians mix epilepsy education, information, and advocacy with enjoying a day at "the happiest place on earth."

Newswise: Should People with Epilepsy Ever Stop Taking Medication?
Released: 3-Feb-2020 8:05 AM EST
Should People with Epilepsy Ever Stop Taking Medication?
International League Against Epilepsy

Medication controls seizures in many people with epilepsy. The drugs are not a cure, but seizures don't always last a lifetime. After years without seizures, is it safe for some people to gradually come off their medications?

Newswise: Hackensack Meridian School of Medicine Launches Grant Program to Help Deliver Breakthroughs in Treatment of Major Diseases and Conditions
Released: 28-Jan-2020 10:05 AM EST
Hackensack Meridian School of Medicine Launches Grant Program to Help Deliver Breakthroughs in Treatment of Major Diseases and Conditions
Hackensack Meridian Health

The six projects selected will be seeded with more than $100,000 in total to help the scientists generate preliminary investigative results to prepare applications for competitive federal and foundation awards.

Newswise: Epilepsy Study Shows Link Between Brain Activity and Memory
Released: 6-Jan-2020 9:00 AM EST
Epilepsy Study Shows Link Between Brain Activity and Memory
Cedars-Sinai

A new study reveals how memory and abnormal brain activity are linked in patients with epilepsy who often report problems with memory. The data show that abnormal electrical pulses from specific brain cells in these patients are associated with a temporary kind of memory disruption called transient cognitive impairment.

Newswise: Extra benefit from epilepsy neurostimulators — reducing comorbid neuropsychiatric symptoms
Released: 2-Jan-2020 3:05 PM EST
Extra benefit from epilepsy neurostimulators — reducing comorbid neuropsychiatric symptoms
University of Alabama at Birmingham

Researchers report cases of five epilepsy patients who found better treatments for deleterious neuropsychiatric symptoms like anxiety and depression using data collected — while the patients were at home — from implanted neurostimulators placed in their brains to control their epileptic seizures.

Newswise: 218804_web.jpg
Released: 5-Dec-2019 12:05 PM EST
Patient diaries reveal propensity for epileptic seizures
Rice University

A researcher at Rice University's Brown School of Engineering and an alumna of her lab have the first validation of their program to assess the risk of seizures in patients with epilepsy.

Newswise: Head-to-Head Comparison Finds Three Anti-Seizure Drugs Equally Effective for Severe Form of Epilepsy
27-Nov-2019 10:30 AM EST
Head-to-Head Comparison Finds Three Anti-Seizure Drugs Equally Effective for Severe Form of Epilepsy
Michigan Medicine - University of Michigan

A new clinical trial in the emergency department finds no difference in efficacy or adverse effects of three commonly used treatments for patients with refractory status epilepticus.

Newswise: Investigational Drug for People with Treatment-Resistant Epilepsy
Released: 21-Nov-2019 9:00 AM EST
Investigational Drug for People with Treatment-Resistant Epilepsy
Johns Hopkins Medicine

Imagine not being able to drive, shower alone or even work because you are never quite sure when the next seizure will leave you incapacitated. Hope may be on the horizon for epilepsy patients who have had limited success with seizure drugs. In a study, led by a Johns Hopkins lead investigator, of 437 patients across 107 institutions in 16 countries, researchers found that the investigational drug cenobamate reduced seizures 55% on the two highest doses of this medication that were tested over the entire treatment period.

Released: 21-Nov-2019 8:00 AM EST
NINDS Awards Coriell Institute for Medical Research $7.7 Million Contract
Coriell Institute for Medical Research

The five-year award will support the NINDS Human Genetics Resource Center, a collection of biological samples and corresponding demographic, clinical, and genetic data made available to qualified researchers around the world. This repository includes samples from subjects with various diseases – such as cerebrovascular disease, dystonia, epilepsy, motor neuron disease, parkinsonism, and Tourette Syndrome.

Newswise: Six ways doctors can improve reproductive health in women with epilepsy
Released: 20-Nov-2019 11:10 AM EST
Six ways doctors can improve reproductive health in women with epilepsy
International League Against Epilepsy

With a little time, some information and a few questions, neurologists can help women with epilepsy make choices about birth control, folic acid supplements, and pregnancy.

Newswise: Keck Medicine of USC announces launch of USC Epilepsy Care Consortium to serve epilepsy patients throughout Southern and Central California
Released: 19-Nov-2019 4:40 PM EST
Keck Medicine of USC announces launch of USC Epilepsy Care Consortium to serve epilepsy patients throughout Southern and Central California
Keck Medicine of USC

Keck Medicine of USC announces the launch of the USC Epilepsy Care Consortium, a unique partnership of six independent epilepsy centers serving patients in Los Angeles County, Orange County and the Central Valley.

Newswise: Anti-seizure drugs and pregnancy: New research on safety and prescription patterns
Released: 18-Nov-2019 8:05 AM EST
Anti-seizure drugs and pregnancy: New research on safety and prescription patterns
International League Against Epilepsy

About 600,000 women with epilepsy become pregnant each year. Careful management of anti-seizure medications can reduce risks to both mother and baby.

Newswise: How to improve epilepsy care in Africa? Include traditional healers, schoolchildren and the guy next door
Released: 31-Oct-2019 1:35 PM EDT
How to improve epilepsy care in Africa? Include traditional healers, schoolchildren and the guy next door
International League Against Epilepsy

In Mozambique, most people with epilepsy don’t seek treatment. So the country took on an intimidating challenge: Diagnose and treat more people by increasing awareness, reducing stigma, improving medication access, and partnering with traditional healers.

Newswise: First structure of human cotransporter protein family member solved
Released: 29-Oct-2019 2:05 AM EDT
First structure of human cotransporter protein family member solved
UT Southwestern Medical Center

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles – ions – across the cell membrane.

Newswise: Parents of adults with epilepsy: Caregiving without a net
Released: 21-Oct-2019 8:05 AM EDT
Parents of adults with epilepsy: Caregiving without a net
International League Against Epilepsy

When an adult child is diagnosed with epilepsy, their parents face a wide array of social, emotional and financial issues, often with very little support. Striking a balance between caring for their child and allowing independence can be difficult and frustrating.

11-Oct-2019 11:05 AM EDT
Cleveland Clinic-led Research Team Develops New Genetic-based Epilepsy Risk Scores
Cleveland Clinic

An international team of researchers led by Cleveland Clinic has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment.

Newswise: 212834_web.jpg
Released: 1-Oct-2019 2:05 PM EDT
Epilepsy: Function of 'brake cells' disrupted
University of Bonn

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted.

Newswise: Predicting Epileptic Seizures Might Be More Difficult Than Previously Thought
23-Sep-2019 11:05 AM EDT
Predicting Epileptic Seizures Might Be More Difficult Than Previously Thought
American Institute of Physics (AIP)

By studying the brain dynamics of 28 subjects with epilepsy, scientists demonstrated there is no evidence for a previously suspected warning sign for seizures known as “critical slowing down,” which refers to characteristic changes in the behavior of a complex system that approaches a theoretical tipping point; when this point is exceeded, there can be impactful and devastating changes. The researchers discuss their work in this week’s Chaos.

Newswise: Screening for depression in people with epilepsy: Improve care, save lives
Released: 23-Sep-2019 7:05 AM EDT
Screening for depression in people with epilepsy: Improve care, save lives
International League Against Epilepsy

Any neurologist who sees patients with epilepsy also sees patients with undiagnosed depression. A simple screening tool can improve outcomes and save lives.

Newswise: Epilepsy and caregiver stress: How one family counters stress by giving back
Released: 20-Sep-2019 9:50 AM EDT
Epilepsy and caregiver stress: How one family counters stress by giving back
International League Against Epilepsy

Epilepsy affects entire families, with impacts on caregivers' physical health, emotional functioning, social relationships, employment and finances. Caregivers and siblings are at risk for post-traumatic stress. Here's how one family works to channel their stress and frustration into helping others.

Newswise: Two families' experiences with epilepsy: Stress, love, responsibility
Released: 28-Aug-2019 9:40 AM EDT
Two families' experiences with epilepsy: Stress, love, responsibility
International League Against Epilepsy

Being a parent or sibling of someone with epilepsy is life changing. Family members share their stories.

Newswise: Epilepsy and the family: Caregiver stress and sibling experiences
Released: 27-Aug-2019 11:05 AM EDT
Epilepsy and the family: Caregiver stress and sibling experiences
International League Against Epilepsy

Epilepsy affects entire families. Research shows that uncontrolled seizures can lead to the development of PTSD in caregivers and siblings. Family members also may struggle with anxiety and depression, as well as guilt and fear.

Newswise: The other side of seizure freedom:
AUDIO
Released: 27-Aug-2019 10:05 AM EDT
The other side of seizure freedom: "I kind of wish my epilepsy was back"
International League Against Epilepsy

It might seem that there’s no downside to successful epilepsy surgery. Who wouldn’t want to be free of seizures that limit their life? But there are challenges to seizure freedom after years of living with epilepsy. The “burden of normality” can disrupt a person’s life and their relationships.

Newswise: Firework Memories
Released: 16-Aug-2019 12:00 PM EDT
Firework Memories
Weizmann Institute of Science

Prof. Rafael Malach’s lab has revealed a neuronal mechanism central to free recall. Working with people hospitalized with epilepsy who had implanted electrodes, the team recorded, for the first time, “hippocampal ripples” – synchronized bursts of activity that Prof. Malach calls “a nerve-cell fireworks display.”

Released: 14-Aug-2019 7:00 AM EDT
Nerve Stimulation + Repetitive Sounds Help Improve Hearing
American Physiological Society (APS)

Combining seizure-preventing electrical stimulation with repetitive musical tones improves processing of sounds in the brain, according to new research. The discovery may provide relief for chronic ringing in the ears (tinnitus) and aid communication skills in people with autism. The first-of-its-kind study, published ahead of print in the Journal of Neurophysiology (JNP), was chosen as an APSselect article for August.

Newswise: Epilepsy Is a Threat to Public Health, Says International Report
Released: 29-Jul-2019 10:05 AM EDT
Epilepsy Is a Threat to Public Health, Says International Report
International League Against Epilepsy

Worldwide, more than 50 million people are living with epilepsy. As many as 37 million are not receiving treatment, though it can cost as little as US$5 a year and eliminates seizures about two-thirds of the time. These findings and many others are published in "Epilepsy: A public health imperative", a report produced by ILAE, the World Health Organization and the International Bureau for Epilepsy.

Newswise: First Surgery with ROSA® Brain Robot in New Jersey 
Performed at Overlook Medical Center
Released: 29-Jul-2019 4:00 AM EDT
First Surgery with ROSA® Brain Robot in New Jersey Performed at Overlook Medical Center
Atlantic Health System

The first surgery in New Jersey using the ROSA Brain robot was performed by Ronald Benitez, MD, chief of endovascular neurosurgery, Overlook Medical Center. Conventional brain surgery for epilepsy requires a craniotomy. Using ROSA Brain, surgeons make tiny holes in the skull through which they insert electrodes to record brain activity and help pinpoint exactly which part of the brain is responsible for seizures. The robot can also assist in deep brain stimulation, trans-nasal and ventricular endoscopy, and brain biopsies.

Newswise:Video Embedded preclinical-study-of-therapeutic-strategy-for-lafora-disease-shows-promise
VIDEO
25-Jul-2019 8:05 AM EDT
Preclinical Study of Therapeutic Strategy for Lafora Disease Shows Promise
University of Kentucky

A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease (LD), a fatal form of childhood epilepsy. This new type of drug is a first-in-class therapy for LD and an example of precision medicine that has potential for treating other types of aggregate-based neurological diseases.


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