Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy.
Studying genes in families with a propensity for certain diseases has led to many critical advances in medicine, including the discovery of statins in family members who suffered heart attacks at an early age.
A multidisciplinary research group specializing in pediatrics, genetics, and psychophysics, co-led by the Monell Chemical Senses Center, has identified wide variation in the sensory perception of a pediatric formulation of ibuprofen — some that were tied to genetic ancestry, and some that were not.
It is a heartbreaking condition that robs children of their ability to walk, talk and recognise their loved ones and now the latest research has revealed the true impact of childhood dementia globally.
The African BioGenome Project, a large-scale international research project involving Konstanz bioinformatician Abdoallah Sharaf, successfully launched its “Open Institute”. The institute’s mission: accelerating knowledge exchange in biodiversity genomics and bioinformatics.
Certain genetic influences contribute to disordered eating and problematic alcohol use, leaving some people vulnerable to both conditions, according to a large study of late adolescent twins. Previous research has found concurrent eating disorders and risky drinking in younger teens amplify the chance of worse outcomes, including death.
Scientists figuring out which of the 5,000-plus genetic variants associated with schizophrenia have an actual causal effect in the development of the condition. Some of genetic variants regulate or alter the expression of genes involved in the condition.
Researchers at The Ohio State University Wexner Medical Center and led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
Ecologists have demonstrated that the genetic material that species shed into their environments can reveal not only the presence of the species but also a broad range of information about the genetics of whole populations — information that can help scientists trace the source of a new invasive population as well as prevent further invasion.
A phase 2 study, led by Thomas W. Ferkol, MD, at the UNC School of Medicine, demonstrates safety and efficacy of idrevloride with hypertonic saline for treatment of primary ciliary dyskinesia, a rare genetic disorder that can lead to permanent lung damage.
Scientists have opened a new view into the workings of the brain and central nervous system, detecting a diverse set of important molecules known as lipoproteins. The most common protein on the particles is apolipoprotein E; one form of APOE puts people at higher risk of Alzheimer’s disease.
Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.
Researchers investigated the relationship between historical trauma experienced by Alaska Native communities and epigenetic markers on genes that previous studies have linked to trauma.
Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.
Opposites don’t actually attract. That’s the takeaway from a sweeping CU Boulder analysis of more than 130 traits and including millions of couples over more than a century.
The linguist have developed the comparison of the genetic code with language where nucleotides act as letters, and introduced the concept of “a semiotic nucleotide” – the minimal element which makes it possible distinguishing between codons – coding units of DNA.
The largest genetic study of its kind, coordinated by the International League Against Epilepsy (ILAE), has discovered specific changes in our DNA that increase the risk of developing epilepsy.
A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.
A new study from the University of Michigan Department of Neurosurgery and Rogel Cancer Center shows promising early results that a therapy combining cell-killing and immune-stimulating drugs are safe and effective in extending survival for patients with gliomas, a highly aggressive form of brain cancer.
UChicago Medicine Comer Children’s Hospital was one of three sites to enroll patients in a clinical trial to test a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.
A multi-site, five-year study led by a MedStar Heart & Vascular Institute cardiologist and fellow researchers from across the country have demonstrated the benefits of routine genetic testing for patients with advanced disease from dilated cardiomyopathy (DCM), a disease of the heart muscle and their at-risk family members.
A special antibody derived from llamas —called a nanobody — can stop the misfolding and the activation of Rhodopsin, a molecule whose mutations can lead to blindness.
High-quality sequencing of nearly the entire kākāpō population, funded through a Genomics Aotearoa project, is helping New Zealand to manage the health of this critically endangered species.
PNP editing emerges as a versatile and programmable tool for site-specific DNA manipulations.
The hereditary molecule DNA can store a great deal of information over long periods of time in a very small space.
Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.
A new study published in iScience, by Hong Wang, PhD, an Associate Member at the Monell Chemical Sense Center, and colleagues sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.
Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.
A new study led by a researcher at New York Institute of Technology provides insight that could change how scientists and clinicians understand genetic predisposition to breast cancer, a condition that affects one in eight U.S. women in her lifetime.
CureMD, a leading provider of comprehensive technology solutions for community oncology, is proud to announce its partnership with Tempus, a leader in artificial intelligence and precision medicine, to integrate Tempus' advanced genomic testing capabilities into CureMD's cutting-edge Electronic Health Record (EHR) system.
Clopidogrel is a commonly prescribed medication used to prevent further heart attacks after an initial event. It needs to be activated in the body to be effective.
A $3 million, five-year award from the National Institute of Environmental Health Sciences of the NIH aims to discover and validate the gene Х heavy metal (GXM) interactions in human livers and to understand their role in nonalcoholic fatty liver disease
Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.
A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
Researchers at the University of Idaho have found a unique, non-invasive way to identify polar bears in the Arctic by scraping DNA from a bear’s paw print.
Imagine a few roughly cut slices of bread on a plate. With just those slices, could you picture, in fine detail, the loaf they came from?
A combination approach of increasing the SIRT3 protein and inhibiting PARPs (poly-ADP ribose polymerase) helps rescue motor endurance of mice modeling the neuromuscular disease spinal bulbar and muscular atrophy (SBMA), also known as Kennedy’s disease, according to a new study by Philadelphia College of Osteopathic Medicine (PCOM) researchers.
Humans have a positive view of nature. But is this due to an approach we have learned while growing up, or is it something we are born with?
Joan Conaway, Ph.D., Vice Provost and Dean of Basic Research at UT Southwestern Medical Center, has been elected President-Elect of the American Society of Biochemistry and Molecular Biology (ASBMB), one of the largest scientific societies in the world.
Doctors try to improve the life of a four-year-old with a rare genetic disease and other patients like her
Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.
Todd Aguilera, M.D., Ph.D., Assistant Professor of Radiation Oncology and member of the Experimental Therapeutics Program in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center, has been named one of 11 inaugural Cancer Moonshot Scholars. The national program recognizes a cohort of early-career investigators from underrepresented groups who have been identified as emerging leaders in cancer research and innovation.
Parents can be so protective of a child with congenital heart disease they often forget what comes next. When should they start learning to take care of their own condition? Two Penn State Health experts share their views.
Research team used advanced sequencing technology to analyze Ötzi’s genome to obtain a more accurate picture of the Iceman’s appearance and genetic origins.
Jane Carlton, PhD, a biologist and leader in the field of comparative genomics, has joined the Johns Hopkins Bloomberg School of Public Health as director of the Johns Hopkins Malaria Research Institute. She assumed the role on August 1.
Researchers at Tel Aviv University have developed a computational model that makes it possible to predict each woman's genetic risk of developing breast cancer based on her genetic profile.
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules.
Gliomas are incurable brain tumors. Researchers are trying to unlock the mysteries of how they originate from normal cells, which may lead to better treatments.
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