NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration. The nanoparticle carriers have the potential to significantly expand the effectiveness of gene therapies for human eye diseases, including blindness.
Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found. Offspring sex may also interact with maternal immune conditions to influence outcomes, particularly in terms of a child’s cognition.
Research from the McKelvey School of Engineering at Washington University in St. Louis has determined that locusts can smell explosives and determine where the smells originated — an important step in engineering cyborg bomb-sniffing locusts.
A series of simulations using multiple supercomputers, including Comet at the San Diego Supercomputer Center (SDSC) at UC San Diego, suggests that when the neutron stars’ masses are different enough, the result is far noisier. The models predicted an electromagnetic ‘bang,’ which isn't present when the merging stars' masses are similar, according to researchers.
The University of Arkansas at Little Rock has received state and federal approval to award a services contract to NuShores Biosciences LLC for Generation 1 manufacturing of the NuCress bone void filler scaffold products. This contract is funded by a $5.6 million grant awarded by the Department of Defense to UA Little Rock in 2019.
David Williams, PhD, has been selected as the 2021 RPB David F. Weeks Award for Outstanding Vision Research. The Weeks Award, funded through the generosity of Research to Prevent Blindness, an anonymous donor, and the Association of University Professors of Ophthalmology, annually recognizes and celebrates an excellent vision researcher.
From Sinatra to Katy Perry, celebrities have long sung about the power of a smile – how it picks you up, changes your outlook, and generally makes you feel better. But is it all smoke and mirrors, or is there a scientific backing to the claim? Groundbreaking research from the University of South Australia confirms that the act of smiling can trick your mind into being more positive, simply by moving your facial muscles.
DALLAS – Aug. 12, 2020 – In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s characteristic symptoms and promoted recovery in symptomatic animals, UTSW scientists report.
The Simms/Mann-UCLA Center for Integrative Oncology has received a $50,000 grant from Los Angeles-based PHASE ONE Foundation to support psychosocial care for people with cancer, their families and frontline healthcare workers during the COVID-19 pandemic.
Up to one-third of physicians reported sending patients for a thyroid ultrasound for reasons not supported by clinical care guidelines, a new study led by University of Michigan Rogel Cancer Center researchers finds. Routine use of ultrasounds to detect cancerous thyroid nodules have led to a significant increase in thyroid cancer cases in recent years, although many are low-risk and unlikely to cause serious harm.
Rutgers researchers have been awarded a $20 million grant by the National Institutes of Health (NIH) to evaluate new point of care tests that would diagnose Tuberculosis, the number one cause of deaths worldwide due to an infectious disease.
Researchers at Washington University School of Medicine in St. Louis have created a COVID-19 vaccine candidate from a replicating virus. This experimental vaccine has proven effective at preventing pneumonia in mice.
“Older adults might be representing events in different ways, and transitions might be picked up differently than, say, a 20-year-old,” said Zachariah Reagh, assistant professor of psychological and brain sciences in Arts & Sciences. Reagh looked at fMRI images to study memory differences in different age groups.
Children wearing multifocal contact lenses had slower progression of their myopia, according to results from a clinical trial funded by the National Eye Institute, part of the National Institutes of Health. The findings support an option for controlling the condition, also called nearsightedness, which increases the risk of cataracts, glaucoma and retinal detachment later in life. Investigators of the Bifocal Lenses In Nearsighted Kids (BLINK) Study published the results August 11 in the Journal of the American Medical Association.
In a mouse study, researchers at Washington University School of Medicine in St. Louis have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.
Chemotherapy usually cures children diagnosed with acute lymphoblastic leukemia (ALL), but the treatment may hamper brain development and impact key cognitive functions including sensory processing, memory, and attention. Researchers at Albert Einstein College of Medicine, Children’s Hospital at Montefiore (CHAM), and Rutgers Cancer Institute of New Jersey have received a five-year, $4.6 million grant from the National Institutes of Health (NIH) to determine how chemotherapy exerts its damaging effects on the brain. Their long-term objective is to use this information to develop protective interventions that can prevent permanent harm.
Cervical cancer kills over 300,000 women a year, and 19 of the 20 nations with the highest death rates are sub-Saharan countries. Now an international team has published the first comprehensive genomic study of cervical cancers in sub-Saharan Africa, with a focus on tumors from 212 Ugandans.
In the first large, multicenter analysis of its kind, the 40-hospital UPMC health system today reported its findings on clinician-directed retesting of patients for presence of SARS-CoV-2, the virus that causes COVID-19.
Whole grain labels are confusing to consumers, according to a new study that found many made the wrong choice when asked to pick the healthier option based on product labels. The researchers, from Tufts University and NYU, say the results provide legal evidence for changes in labeling policies.
A new UC Davis Health study found that common gastrointestinal (GI) symptoms such as diarrhea, constipation and bloating are linked to troubling sleep problems, self-harm and physical complaints in preschool children. According to the study, published Aug. 6 in Autism Research, these GI symptoms are much more common and potentially disruptive in young kids with autism.
Virginia Institute of Marine Science (VIMS) researchers used supercomputer simulations to examine impacts of both regional and global changes affecting the Chesapeake Bay. They discovered that historical increases in fertilizers and atmospheric carbon dioxide concentrations have forced the bay to behave increasingly like a small sea on a continental shelf rather than a traditional estuary.
This research will focus on the development of efficient electrochemical systems for energy generation and storage. The proposed work will have a significant impact on the development of efficient energy conversion systems.
DALLAS – Aug. 7, 2020 – UT Southwestern scientists have developed a genetically engineered mouse and imaging system that lets them visualize fluctuations in the circadian clocks of cell types in mice. The method, described online in the journal Neuron, gives new insight into which brain cells are important in maintaining the body’s master circadian clock. But they say the approach will also be broadly useful for answering questions about the daily rhythms of cells throughout the body.
The University of Alabama in Huntsville (UAH) will receive $1.1 million of the $3.3 million in research, education and training grants awarded to universities that comprise the Alliance for System Safety of UAS through Research Excellence (ASSURE).
UC San Diego researchers formulated polyurethane foams, made from algae oil, to meet commercial specifications for midsole shoes and the foot-bed of flip-flops. Their latest result, in a series of recent research publications, offers a complete solution to the plastics problem—at least for polyurethanes.
Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient's health. Researchers are developing a method to diagnose brain tumors without any incisions.
A new study documents how 49 hospitals in a state hit hard by COVID-19 changed their visitor policies and communications with families of intensive care unit patients in the first months of the pandemic -- and how those efforts varied. Virtually all hospitals put in place a “no visitors” blanket policy, but 59% of them did allow some exceptions to this rule.
Researchers from Tufts have discovered neural mechanisms in mice specific to females that switch estrogen from playing a protective role in glucose metabolism to a disruptive role. The discovery could provide clues to the increased risk of insulin resistance and diabetes among post-menopausal women.
New research by neuroscientists at the University of Pittsburgh and UC San Francisco (UCSF) revealed that a simple, earbud-like device developed at UCSF that imperceptibly stimulates a key nerve leading to the brain could significantly improve the wearer’s ability to learn sounds of a new language.
The Cancer Research Institute (CRI), a U.S. nonprofit organization dedicated to the discovery and development of powerful immunotherapies for all cancers, awarded more than $30.2 million in research grants and fellowships in the 2020 fiscal year ending June 30, 2020.
Laura Fields has won an Early Career Research Award from the Department of Energy to help physicists better understand the composition of neutrino beams used by Fermilab experiments. Her work will help gather and validate results that could shed light on why the universe consists of something rather than nothing.
Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of pancreatic cancer, called metastasis, when inhibited in mice. Published in Gastroenterology, the findings are a first step toward a potential treatment for one of the deadliest cancers known today.
The American Academy of Ophthalmology and Research to Prevent Blindness (RPB) today announced the recipients of the Research to Prevent Blindness/American Academy of Ophthalmology Award for IRIS® Registry Research.
Study finds that men who harbor more harmful attitudes about masculinity – including beliefs about aggression and homophobia – also tend toward bullying, sexual harassment, depression and suicidal thoughts.
Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, published today in the Journal of Experimental Medicine (JEM), also suggests that, rather than protecting the lungs, key antiviral signaling proteins may actually cause much of the tissue damage associated with COVID-19.
A new study led by scientists at La Jolla Institute for Immunology (LJI) shows that memory helper T cells that recognize common cold coronaviruses also recognize matching sites on SARS-CoV-2, the virus that causes COVID-19.
A new grant awarded to the Perelman School of Medicine at the University of Pennsylvania will help identify methods to improve uptake of state-of-the-science care that can have a significant impact for patients.