A ribosomal traffic jam that breaks the heart
Kyushu UniversityA team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.
A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.
The new research findings, published in March in the Journal of the American College of Cardiology, used data from the Coronary Artery Risk Development in Young Adults (CARDIA), which recruited about 5,000 healthy young adults from four U.S. cities and followed them for 30 years. The researchers were able to calculate from this data the cumulative effect of individual risk factors, such as high blood pressure, diabetes, elevated cholesterol, and the additive effects of multiple risk factors that can cause cardiovascular disease.
Lesbian and bisexual women were less likely to have ideal cardiovascular health scores compared to heterosexual women, which should make them a priority group for cardiovascular disease prevention, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
Building the skills for cardiopulmonary resuscitation (CPR) can begin as early as age 4 and layer on as children get older, so that by age 10 they may be able to perform effective chest compressions on training manikins, according to a new scientific statement from ILCOR, the American Heart Association and the European Resuscitation Council.
A machine learning-based model that enables medical institutions to predict the mortality risk for individual cardiac surgery patients has been developed by a Mount Sinai research team, providing a significant performance advantage over current population-derived models.
First-generation bioresorbable vascular scaffolds (BVS) may be just as effective as drug-eluting metallic stents, which are currently the standard treatment for heart disease patients undergoing percutaneous coronary intervention (PCI).
A new study reveals a staggering disparity in life expectancy between Black Americans and their white counterparts between 1999 and 2020. In an analysis of U.S. data, a Yale-led team of researchers found 1.63 million excess deaths in the Black population compared with white Americans, representing more than 80 million excess years of potential life lost.
Every year, between 1,200 and 1,500 patients suffer a cardiac arrest in Norwegian hospitals. Rapid and sound treatment is absolutely essential in helping these patients survive. Even if a patient suffers a cardiac arrest within the hospital's four walls, the prognosis is poor. Only one in four survives. However, a new study suggests that easily available informaiton from the patient's own ECG could change the outcome.
Ion channels in people with Cantu syndrome produce varying degrees of contractile dysfunction (when muscles and tendons function ineffectively) in the lymphatic system, according to a new research study in the journal Function.
Katy Winckworth-Prejsnar, MPH, Senior Manager of Global Policy and Strategic Alliances for National Comprehensive Cancer Network (NCCN), to Co-Chair Non-Communicable Diseases Roundtable for the Global Health Council (GHC)
Seemingly healthy people whose blood contained antibodies associated with a condition called antiphospholipid syndrome (APS) were significantly more likely to experience a cardiovascular event such as a heart attack or stroke than those without, a study led by UT Southwestern Medical Center scientists shows
The Guerin Family Congenital Heart Program in the Smidt Heart Institute at Cedars-Sinai has earned accreditation from the Adult Congenital Heart Association, becoming one of only six programs in California and just 50 in the U.S. to be awarded the organization’s highest distinction.
The Cardiovascular Research Foundation (CRF) announced that TVT: The Structural Heart Summit will feature 15 Late-Breaking Clinical Science studies. An annual meeting featuring cutting-edge research and techniques for structural heart interventions, TVT will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.
Eric Bredahl, PhD, and his team of undergraduate research assistants are trusting that Nature, if asked nicely, or at least insistently, will yield another of her secrets.
The UCLA Center for SMART Health, an interdisciplinary collaborative that looks to the integrated transformation of healthcare through emergent data and technologies, and Hearst Health, a division of Hearst and leader in care guidance, announced Thursday that Stanford Medicine is the winner of the 2023 Hearst Health Prize.
A new study from Keck Medicine of USC published in the Annals of Internal Medicine shows that heavy alcohol use may be dramatically more damaging to the liver for people with metabolic syndrome.
Chaos congratulates Yuzuru Kato, Thomas Lilienkamp, and Tiemo Pedergnana for winning the journal’s 2022 Edward N. Lorenz Early Career Awards. Kato was recognized for introducing a definition of a phase function for quantum rhythmic systems, Lilienkamp was commended for developing a low-energy and safer approach to defibrillation, and Pedergnana was selected for work to better understand if and how an exact potential, which greatly simplifies analysis of the Langevin equation, can be found for a given system. The winners will split a $2,000 honorarium and are invited to contribute a perspective article to the journal.
Researchers show phospholipid derivatives from a Western diet promote increased levels of gut-derived bacterial toxins, systemic inflammation, atherosclerosis plaque formation
It’s a common misconception that older adults need less sleep than those younger, but many get fewer hours due to insomnia and various health problems, including sleep apnea and heart trouble. In addition to a reduced quality of life, long-term health consequences of poor sleep include high blood pressure, weight gain, stroke, heart attack, diabetes, memory problems, and even increased risk of death, said Deborah Freeland, M.D., Assistant Professor of Internal Medicine and a member of UTSW’s Division of Geriatric Medicine.
In medicine and science, the term “pathogenesis” describes the origin and development of disease. There is not, however, a broadly accepted term to describe the other half of the equation: the process of healing and recovery.
In a study publishing May 10 in JAMA Cardiology, senior author and UCSF cardiologist Geoff Tison, MD, MPH, and first author Robert Avram, MD, of the Montreal Heart Institute, set out to determine whether deep neural networks (DNNs), a category of AI algorithm, could be used to predict cardiac pump (contractile) function from standard angiogram videos. They developed and tested a DNN called CathEF, to estimate LVEF from coronary angiograms of the left side of the heart.
In an effort to determine the cause behind a rare condition that causes heart failure in children, University of Maryland School of Medicine researchers have identified new gene mutations responsible for the disorder in an infant patient. They were then able to learn how the mutation works and used a drug to reverse its effects in heart muscle cells derived from stem cells from the patient.
Efforts are underway to address the “epidemic of loneliness and isolation” affecting the country, as recently addressed by the U.S. Surgeon General Dr. Vivek Murthy who is laying out a “National Strategy to Advance Social Connection” initiative. Virginia Tech neuroscientist Georgia Hodes says that reports of depression and anxiety are up at least 3-fold since the start of the COVID epidemic.
Black and Hispanic adults at risk of developing cardiovascular disease are less likely to take statin drugs than white adults with the same risk factors, UT Southwestern Medical Center researchers reported in JAMA Cardiology.
Las personas reaccionan al estrés de manera diferente y la manera en que reaccionamos puede repercutir en la posibilidad de desarrollar problemas de salud graves, incluidas enfermedades cardíacas.
Next Sunday will be the first Mother’s Day that Cedars-Sinai pediatrician Tracy Zaslow faces without her mother, Carol, by her side.
An exhaustive cost-benefit analysis of population genetic testing published in Annals of Internal Medicine concludes with a recommendation to U.S. health policymakers to adopt routine testing of adults ages 40 and under for three genetic conditions posing high risk of life-threatening illness.
Each year, 3 out of 10,000 babies will be born with critical left heart obstruction (CLHO). Most infants born with severe left-sided cardiac defects, such as CLHO, require at least three major open-heart surgeries before the age of 5.
Asian Americans have significant differences in genetics, socioeconomic factors, culture, diet, lifestyle, health interventions and acculturation levels based on the Asian region of their ancestry that likely have unique effects on their risk for heart disease and Type 2 diabetes.
Congenital heart disease (CHD) is the most common type of birth defect and the leading cause of mortality from birth defects, affecting about 1% of all live births per year in the United States. With advances in medical therapies and surgical techniques, the survival outcomes of patients with CHD have improved dramatically over the years.
Although the On-X aortic valve and apixaban have been approved for use by the U.S. Food and Drug Administration (FDA), they had not been approved to be used together. Between May 2020 and September 2022, the PROACT Xa randomized, multicenter, open-label trial compared the direct factor Xa inhibitor apixaban (Eliquis) with warfarin in patients with bileaflet carbon aortic valves.
As thoracic researchers consider the myriad effects of COVID-19, they are looking at the impacts of the disease on patients and treatments, as well as care and treatment during the pandemic.
Hypoplastic left heart syndrome (HLHS) is a birth defect that affects normal blood flow through the heart. As the baby develops during pregnancy, the left side of the heart does not form correctly. The Centers for Disease Control and Prevention (CDC) estimates that each year about 1,025 babies in the United States are born with hypoplastic left heart syndrome—about one out of every 3,841 babies each year.
When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was unclear, however, what exactly was causing this reaction.
Talking on a mobile for 30 minutes or more per week is linked with a 12% increased risk of high blood pressure compared with less than 30 minutes.
Parents, as well as pediatric healthcare clinicians, may want to protect young people from difficult new about their advanced heart disease but many adolescents and young adults prefer being engaged with medical decision-making.
A new study, published in IOP Publishing’s journal Environmental Research: Health, reveals that Indigenous people in the Amazon Basin are twice as likely to die prematurely from smoke exposure due to wildfires than the broader South American population.
For the first time, researchers performed a successful in-utero surgery to repair a potentially deadly developmental condition by treating an aggressive vascular malformation, called vein of Galen malformation, in a fetus’s brain before birth.
UC Davis Health scientists have received a grant from the American Heart Association to study the effects of chronic stress on cardiovascular disease in underserved populations.
Glucocorticoid therapy is widely used during pregnancies at risk of premature delivery to promote fetal lung maturation. While it is an effective treatment, it can also trigger heart and blood vessel problems. New research published in The FASEB Journal uncovers the mechanisms behind the cardiovascular-related effects of the most commonly used glucocorticoids, Dexamethasone (Dex) and Betamethasone (Beta).
Left ventricular conduction disease occurs when there is an electrical blockage of the heart’s normal electrical conduction system. Treatment to lessen its effects involves implanting a permanent pacemaker, but there have been no proven preventive strategies for this condition. In a study publishing May 3, 2023 in JAMA Cardiology, first author Emilie Frimodt-Møller, MD, and senior author Gregory Marcus, MD, MAS, found that intensive BP control is associated with lower risk of left ventricular conduction disease, indicating left ventricular conduction disease may be preventable.
New research highlights potential safety concerns around women taking romosozumab, a new anti-osteoporosis drug available on the NHS. The University of Bristol-led study, published in Arthritis & Rheumatology, analysed genetic data on nearly 34,000 people.
Mountainside Medical Center received an “A” Hospital Safety Grade from The Leapfrog Group, a national nonprofit upholding the standard of patient safety in hospitals and ambulatory surgery centers. This distinction celebrates the hospital’s achievements in prioritizing patient safety by protecting patients from preventable harm and errors.
For millions of Americans that suffer from seasonal allergies (pollen and mold), climate change is exacerbating an earlier, longer, and overall worse allergy season.
Throughout the American Association for Thoracic Surgery (AATS) Annual Meeting, taking place May 6-9 in Los Angeles, experts from the Smidt Heart Institute at Cedars-Sinai will be available to discuss advances and innovations in cardiothoracic surgery.
The program guide for TVT 2023: The Structural Heart Summit is available online. An annual meeting from the Cardiovascular Research Foundation (CRF), TVT features cutting-edge research and techniques for structural heart interventions and will take place June 7-10, 2023, at the Phoenix Convention Center – West in Phoenix, Arizona.