Seemingly healthy people whose blood contained antibodies associated with a condition called antiphospholipid syndrome (APS) were significantly more likely to experience a cardiovascular event such as a heart attack or stroke than those without, a study led by UT Southwestern Medical Center scientists shows
In a recently published commentary, UK HealthCare physicians call for standard-of-care treatment for opioid use disorder (OUD) among patients who are incarcerated.
The anti-dementia medication lecanemab and its ancillary costs could add $2 billion to $5 billion in annual Medicare spending if the Centers for Medicare and Medicaid Services (CMS) revise their coverage decision. Currently, the medication is covered only for patients who are enrolled in clinical trials.
In a study publishing May 10 in JAMA Cardiology, senior author and UCSF cardiologist Geoff Tison, MD, MPH, and first author Robert Avram, MD, of the Montreal Heart Institute, set out to determine whether deep neural networks (DNNs), a category of AI algorithm, could be used to predict cardiac pump (contractile) function from standard angiogram videos. They developed and tested a DNN called CathEF, to estimate LVEF from coronary angiograms of the left side of the heart.
Study following Chicagoans over a 25-year period suggests over half of the city’s Black and Hispanic population, and a quarter of its White population, have seen a shooting by age 40.
In this study, patients using medical cannabis reported improvements in health-related quality of life, which were mostly sustained over time. Adverse events were rarely serious but common, highlighting the need for caution with prescribing medical cannabis.
Repeated mammograms contain data on changes in breast density over time that could help identify women at high risk of breast cancer and even reveal which breast is likely to be affected, according to a study by researchers at Washington University School of Medicine in St. Louis.
Black and Hispanic adults at risk of developing cardiovascular disease are less likely to take statin drugs than white adults with the same risk factors, UT Southwestern Medical Center researchers reported in JAMA Cardiology.
Contrary to popular belief, firearm deaths in the United States are statistically more likely in small towns, not major cities, according to new research.
After a stroke, physical activity can be pivotal to successful recovery. People who spend four hours a week exercising after their stroke achieve better functional recovery within six months than those who do not, a University of Gothenburg study shows.
A sharp increase in the price of the gout drug colchicine, the result of an unusual FDA policy, led to lower use and poorer disease control. The findings have implications for other drugs, whose price could be similarly affected by government policies and manufacturer decisions.
People who perceived that they had cognitive difficulties such as memory problems during COVID were more likely to have lingering physical manifestations of the disease than people who did not report cognitive issues.
Parents, as well as pediatric healthcare clinicians, may want to protect young people from difficult new about their advanced heart disease but many adolescents and young adults prefer being engaged with medical decision-making.
Upon an arrival to the emergency department for abdominal pain of unknown cause, most non-pregnant adult patients receive a CT scan with IV contrast to diagnose the source of the pain. However, IV contrast can be a risk in patients with severe kidney disease or at risk for an allergic reaction from the dye. When scans are performed without IV contrast, though, they are usually less accurate, which can lead to misdiagnosis.
Acute radiation dermatitis (ARD)—characterized by red, sore, itchy or peeling skin—affects up to 95% of people undergoing radiation treatment for cancer. Severe cases can cause significant swelling and painful skin ulcers that can severely impair quality of life, yet little is known about why this condition occurs and no standardized treatments for preventing severe ARD have been widely adapted.
Left ventricular conduction disease occurs when there is an electrical blockage of the heart’s normal electrical conduction system. Treatment to lessen its effects involves implanting a permanent pacemaker, but there have been no proven preventive strategies for this condition. In a study publishing May 3, 2023 in JAMA Cardiology, first author Emilie Frimodt-Møller, MD, and senior author Gregory Marcus, MD, MAS, found that intensive BP control is associated with lower risk of left ventricular conduction disease, indicating left ventricular conduction disease may be preventable.
A new study found a declining proportion of DATA-waivered clinicians prescribed any buprenorphine between 2017 and 2021. While the number of waivered clinicians increased significantly during the five-year window, only one out of three prescribed any buprenorphine as of May 2021. Furthermore, the majority of prescriptions were written by clinicians who specialize in treating opioid use disorder. The new study was published as a research letter in JAMA.
Applying machine learning models, a type of AI, to data collected passively from wearable devices can identify a patient’s degree of resilience and well-being, according to investigators at the Icahn School of Medicine at Mount Sinai in New York. The findings, reported in the May 2nd issue of JAMIA Open, support wearable devices, such as the Apple Watch®, as a way to monitor and assess psychological states remotely without requiring the completion of mental health questionnaires.
Internet search trends may immediately capture how society seeks information related to reproductive health care, according to new research from Indiana University researchers.
Research from Cedars-Sinai Cancer detailing the largest examination to date of prostate cancer in transgender women, as well as treatment options that improve outcomes in patients with recurrent prostate cancer, will be presented during the American Urological Association (AUA) annual meeting April 28-May 1 in Chicago.
A study of ChatGPT found the artificial intelligence tool answered less than half of the test questions correctly from a study resource commonly used by physicians when preparing for board certification in ophthalmology.
The Perceptions of Research Trustworthiness (PoRT), described in an original investigation published in JAMA Network Open, is a groundbreaking tool designed as an on-going gauge of perception of trust and distrust in biomedical research, said team leader Consuelo H. Wilkins, MD, MSCI, Senior Vice President and senior associate dean for Health Equity and Inclusive Excellence and professor of Medicine at Vanderbilt University Medical Center (VUMC).
As a result of demographic change, the proportion of older oncology patients is rising sharply. Compared to younger patients, cancer treatment is highly individualised due to more frequent and sometimes severe comorbidities, increasing age-related infirmities and reduced physical fitness.
First-ever randomized clinical trial linked to registry data from ACS NSQIP published in JAMA.
Treating opioid addiction should be much easier now than it was a few years ago, thanks to pandemic-era rule changes that aim to improve access to buprenorphine, a medicine proven to help in recovery. But a new study shows prescriptions and adherence rates have remained flat.
A new study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with Dell Medical School, University of Minnesota, and the Vanderbilt University Medical Center, using a national data sample from the National Institutes of Health All of Us Research Program, revealed that a small but statistically significant proportion of patients with cancer, especially younger and lower-income minorities, disproportionately reported delaying care because of patient/clinician racial, gender and cultural differences.
Researchers have identified a strong association between prevalence of prescription stimulant therapy for attention-deficit/hyperactivity disorder (ADHD) and rates of prescription stimulant misuse (taken in a way other than as directed by a clinician) by students in middle and high schools.
Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit. A new study led by researchers at Brigham and Women’s Hospital, a founding member of Mass General Brigham, used public Medicare data to identify the 50 highest-selling brand-name drugs in 2020.
Their experiment shows that children will eat significantly more fruits and vegetables if they on average stay at the table for only ten minutes more – 30 minutes in total. On average, they ate about 100 grams more fruits and vegetables.
U.S. middle and high schools with the most students taking prescription stimulants to treat ADHD also had, overall, the highest percentage of students who misused prescription stimulants within the past year.
New research from Boston Medical Center concluded that offering medications to treat opioid addiction in jails and prisons leads to a decrease in overdose deaths. Published in JAMA Network Open, the study also found that treating opioid addiction during incarceration is cost-effective in terms of healthcare costs, incarceration costs, and deaths avoided.
The first study to examine evaluation scores for professionalism and interpersonal communication skills among physicians-in-training and what happens afterward as these doctors begin their practice was reported April 11 in . The study tracked 9,340 early-career physicians from across the country.
A study, based on reported cases of new cancer diagnosis to the National Cancer Database (NCDB), estimates roughly 200,000 people with cancer cases weren’t diagnosed or treated at Commission on Cancer-accredited facilities at the onset of the pandemic in 2020, around the same time that triage guidelines recommended delays in cancer-related care.
American College of Surgeons research published in JAMA Surgery reveals the complexities and variations that occurred in cancer reporting in the National Cancer Database (NCDB) because of the pandemic.
Researchers tested whether using open-label placebo could increase the efficacy of methadone treatment for people undergoing care for opioid use disorder.
A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.
A cancer diagnosis can cause financial strain on patients as they cope with the cost of treatment and lost work. But what about their partners? A new study from University of Michigan Rogel Cancer Center researchers surveyed the partners of colorectal cancer patients and found the financial impact of a loved one’s diagnosis also impacts the partner’s health-related quality of life.
In this randomized clinical trial, anakinra did not prevent the need for mechanical ventilation or reduce mortality risk compared with standard of care alone among hospitalized patients with severe COVID-19 pneumonia. Future research should assess anakinra in patients with less severe pneumonia.
This national-level analysis found substantial adverse maternal outcomes among pregnant patients with COVID-19 infection at delivery during the early pandemic in the U.S. Specifically, the odds of severe respiratory complications were increased among pregnant patients with COVID-19 infection at delivery.
New research from the UC Davis School of Medicine shows high blood pressure in early adulthood is associated with worse brain health in late life — especially for men. The results suggest that treating hypertension in young and middle-aged adults may help prevent dementia and Alzheimer’s disease.
A community-based, evidence-based intervention system developed at the University of Washington has been linked to reduced handgun carrying rates among youth growing up in rural areas.
New research evaluating the potential cost savings of a therapy for babies displaying early autism signs has predicted a three dollar return to Australia’s National Disability Insurance Scheme (NDIS) for every dollar invested in therapy.
Research suggests these antibodies may be present in seemingly healthy people, increasing their risk of a heart attack or stroke over time.
Pregnant women whose household tap water had higher levels of lithium had a moderately higher risk of their offspring being diagnosed with autism spectrum disorder, researchers reported in JAMA Pediatrics.
The number of prostate cancer patients in the U.S. choosing active surveillance over surgery or radiation has rapidly increased since 2010, rising from 16% to 60% for low-risk patients and from 8% to 22% for patients with favorable-intermediate-risk cancers, according to a study published today in JAMA Internal Medicine.
Researchers led by a team at UT Southwestern Medical Center have created a statistical model to identify standards for typical, high, or low rates of bleeding after pediatric tonsillectomies. The findings, published in JAMA Otolaryngology-Head & Neck Surgery, could help doctors and hospitals improve outcomes for the third-most common pediatric surgery in the U.S.
Overdose mortality among people age 65 and older quadrupled over 20 years, suggesting the need for greater mental health and substance use disorder policies addressed at curbing the trend.
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