Feature Channels: Kidney Disease

• share
• favorite_border

• share
• favorite_border

• share
• favorite_border

First pediatric international conference on acute kidney injury (AKI) resulted in an expert consensus statement published in the journal JAMA Network Open. In this milestone publication, 46 global experts identify key issues in pediatric AKI and set a focused research agenda for the next five to 10 years.

• share
• favorite_border

Today, advocates of the American Society of Nephrology (ASN) and 21 other kidney health professional and patient organizations are meeting with their congressional delegations, calling on them to protect living donors and improve access to transplantation

• share
• favorite_border

In an analysis from The Netherlands, the proportion of employed stable kidney transplant recipients was 56%.

• share
• favorite_border

Acute kidney injury is among the top causes of hospitalization during a heat wave. New research sheds light on why kidney injury increases during heat waves and why certain populations are at greater risk. The study was chosen as an APSselect article for September.

• share
• favorite_border

The National Cancer Institute (NCI) has renewed UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center Kidney Cancer Program (KCP) Specialized Program of Research Excellence (SPORE) award. First awarded in 2016, the KCP SPORE is focused on translating discoveries and innovation at UT Southwestern into advances in patient care.

• share
• favorite_border

Cálculos renais podem causar dores lancinantes e estão relacionados à doença renal crônica, osteoporose e doença cardiovascular. Pessoas que tiveram cálculo renal uma vez têm 30 por cento de chance de ter outra incidência dentro de cinco anos. Incluir alimentos ricos em cálcio e potássio pode prevenir cálculos renais recorrentes, conforme descoberto pelo estudo da Mayo Clinic.

• share
• favorite_border

肾结石可导致剧烈疼痛，并与慢性肾病、骨质疏松症和心血管疾病相关。对于曾患过肾结石的人来说，在五年内复发的几率为30%。妙佑医疗国际(Mayo Clinic) 的研究发现，食用富含钙和钾的食物可预防肾结石复发。

• share
• favorite_border

Los cálculos renales pueden causar un dolor insoportable y se los asocia con la enfermedad renal crónica, la osteoporosis y la enfermedad cardiovascular. Las personas que tuvieron un cálculo renal por primera vez tienen un 30 por ciento de probabilidades de presentar otro en un periodo de cinco años. Según un estudio de Mayo Clinic incluir alimentos con alto contenido de calcio y potasio puede prevenir la recurrencia de los cálculos renales.

• share
• favorite_border

New clinical equations that estimate individuals’ kidney function have eliminated an adjustment for Black race. This study examined the impact of using these new race-free equations on the accumulation of waiting time for kidney transplantation before a patient needs dialysis.

• share
• favorite_border

Washington, DC (September 16, 2022) —The American Society of Nephrology (ASN) is honored to announce its donation of $25,000 to the onePulse Foundation as a part of ASN’s pledge to bring its values to Florida. ASN encourages others to contribute to this campaign and support the Foundation’s mission to create and support a memorial that opens hearts, a museum that opens minds, educational programs that open eyes, and legacy scholarships that open doors.

• share
• favorite_border

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported. The findings, published in Nature Communications, suggest a strategy for gene therapy with the potential to arrest or cure ADPKD.

• share
• favorite_border

Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).

• share
• favorite_border

• share
• favorite_border

The five-year innovative pilot program offers financial support for trainees entering the field of nephrology, focusing on individuals historically underrepresented in medicine.

• share
• favorite_border

After a rare disease caused organ failure, UC San Diego Heath transplant teams performed a heart, liver and kidney transplant on a patient. The surgery is a first for UC San Diego Health and a first in the nation to use three organs from a donor after circulatory death.

• share
• favorite_border

The latest research and expert commentary on pain management.

• share
• favorite_border

UHN’s Ajmera Transplant Centre and The Centre for Living Organ Donation announce today the launch of a new campaign, Great Actions Leave a Mark, www.greatactions.ca. The campaign showcases through artistic photos and video, the stories and scars (the mark) from 39 living organ donors and transplant recipients across Canada.

• share
• favorite_border

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

• share
• favorite_border

A series of upcoming studies will explore whether the grind of active-duty military life and veterans’ disproportionately high incidence of chronic illness could be tamed by lifestyle interventions designed to achieve a metabolic state of nutritional ketosis.

• share
• favorite_border

Combination therapies show encouraging results in several studies led by Dana-Farber Cancer Institute and presented for the first time at the European Society of Medical Oncology (ESMO) Congress 2022, Paris, France. The studies will be presented both in-person and online on September 9-13, 2022.

• share
• favorite_border

• share
• favorite_border

• share
• favorite_border

McKelvey Engineering, School of Medicine collaborate to develop hydrogel system that preserves the biochemistry and mechanical environments of cultured podocyte cells

• share
• favorite_border

The latest research on plants brought to you by Newswise.

• share
• favorite_border

Kidney transplant recipients experience immune-insufficiency during acute COVID-19.

• share
• favorite_border

New research in rats demonstrates that inhaling amorphous silica particles—of the size released from burning sugarcane—could damage the kidneys. The study, chosen as an APSselect for August, is published ahead of print in the American Journal of Physiology-Renal Physiology.

• share
• favorite_border

In an effort to improve the lives of children and adults with kidney disease, Children’s Hospital of Philadelphia (CHOP) and Penn Medicine are jointly launching the Penn-CHOP Kidney Innovation Center. The first-of-its-kind center will advance research to transform patient care for those of all ages, focusing on the early detection, prevention, and treatment of kidney disease and its complications.

• share
• favorite_border

The KidneyCure Diversity, Equity, Inclusion, and Justice Research Scholar Grant, which was established with a $1 million donation from Otsuka and Visterra that the American Society of Nephrology (ASN) will match, will be awarded every other year beginning in 2023.

• share
• favorite_border

The latest research and expert commentary on the monkeypox outbreak.

• share
• favorite_border

In a choice-based study of patients who were waiting for or had received a kidney transplant, the average respondent would accept a kidney today with 6.5 years of expected survival of the transplanted organ to avoid waiting 2 additional years for a kidney with 11 years of expected survival.

• share
• favorite_border

Kidney cancer encompasses a wide spectrum and can present with extensive metastases or just a handful. However, today all patients are treated the same. They all receive medication.

• share
• favorite_border

In an analysis of data on Medicare beneficiaries starting dialysis in 2008–2015, overall Medicare expenditures for in-center hemodialysis were 11% more than for home-based peritoneal dialysis, and this difference did not change significantly over time as more patients initiated peritoneal dialysis.

• share
• favorite_border

Among healthy middle-aged adults in northern Europe, women tended to have lower kidney function than men, but men’s kidney function subsequently declined at a faster rate during aging.

• share
• favorite_border

Results from relevant studies indicate that gender-affirming hormone therapy may increase blood levels of creatinine (indicating potential kidney dysfunction or simply a change in lean muscle mass) in transgender men but does not significantly impact blood levels of creatinine in transgender women.

• share
• favorite_border

A genetic variation identified in a group of families who are prone to diabetes and kidney failure increases the levels of a type of fat, called ceramides. Therapeutics that prevent this change could be beneficial more broadly to anyone at risk for these conditions.

• share
• favorite_border

Do pediatric kidney transplant patients have better long-term outcomes when their kidney comes from living, biologically unrelated donors compared to deceased donors? A new UC Davis Health study published in the journal Pediatric Transplantation finds that they do.

• share
• favorite_border

• Among US adults with kidney failure receiving dialysis, risk for SARS-CoV-2 infection during the Omicron-dominant period was higher among patients without vaccination and with 1–2 doses compared with 3 doses of mRNA vaccines. • Irrespective of vaccine doses, risk for infection was higher among patients with low circulating levels of anti–SARS-CoV-2 antibodies.

• share
• favorite_border

A new randomized controlled study showed, however, that leaving these asymptomatic stones behind significantly increases the risk of a patient's relapse in the following five years. The findings were published today in the New England Journal of Medicine.

• share
• favorite_border

Today, the US Department of Health and Human Services (HHS) and the American Society of Nephrology (ASN) announced a new prize competition from the Kidney Innovation Accelerator (KidneyX) that seeks to further the development of a fully functional bioartificial kidney.

• share
• favorite_border

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include using a CRISPR screen to identify targets for improved chemotherapy responses, the potential of glutaminase inhibitors as novel treatments in renal cell carcinoma, engineered tumor-infiltrating lymphocytes to overcome immune suppression in ovarian cancer, oncolytic viruses to improve responses in glioblastoma, combination therapy options for KRAS/NRAS-mutant colorectal cancer, and a new treatment target for a subtype of myelodysplastic syndromes.

• share
• favorite_border

Experts are hoping a new requirement that all U.S. transplant centers use a race-neutral formula to determine eligibility for a kidney transplant will improve African American access to lifesaving transplants.

• share
• favorite_border

The American Society of Nephrology (ASN) supports efforts by Congress to improve the US transplant system. Today, the Senate Finance Committee will conduct an oversight hearing, A System in Need of Repair: Addressing Organizational Failures of the U.S.’s Organ Procurement and Transplantation Network (OPTN).

• share
• favorite_border

Kidney stones can cause not only excruciating pain but also are associated with chronic kidney disease, osteoporosis and cardiovascular disease. If you've experienced a kidney stone once, you have a 30% chance of having another kidney stone within five years.

• share
• favorite_border

Among adults in Stockholm, Sweden with low kidney function suggestive of chronic kidney disease in 2009–2017, women were less likely than men to receive a diagnostic code related to kidney disease, be referred to a nephrologist, have their kidney function monitored, and receive guideline-recommended medications.

• share
• favorite_border

Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.

• share
• favorite_border

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance, developed by University of Bristol scientists, is published in Nucleic Acids Research.

• share
• favorite_border

A lecturer of the Faculty of Allied Health Sciences, Chula unveils her research on high egg white protein dietary supplement Albupro Plus, functional food for health lovers, now ready for sale.