Leprosy is one of the world’s oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ.
A Rutgers study of obese adults, all with nonalcoholic fatty liver disease (NAFLD) and morbid obesity (body mass index > 40), has shown that those who underwent bariatric surgery suffered far fewer extreme cardiovascular events subsequently.
Hosted by Chulalongkorn University the APRU APEC University Leaders' Forum 2022 is the first post-pandemic in-person APEC meeting held to foster high-level dialogue between CEOs, policy leaders, university presidents, and top researchers. This event begins Nov 15 at 9 PM EST.
A pioneering protocol developed at Children’s Hospital Los Angeles is reducing overall opioid use, speeding rehabilitation and shortening intensive care unit (ICU) stays for pediatric liver transplant patients—including infants as young as 5 months old.
A ToxSpotlight article in the November 2022 issue of ToxSci assesses the mechanism for cellular accumulation of diglycolic acid while another explores the effect of long-term St. John’s wort administration on acetaminophen-induced acute hepatotoxicity and the involved mechanisms.
New study identifies that first-degree relatives of patients with nonalcoholic fatty liver disease with advanced fibrosis (scarring of the liver) are at a 15% risk of developing the condition.
New research led by researchers at the University of Miami Miller School of Medicine and published in the Journal of Hepatology, suggests that getting a third dose of the COVID-19 mRNA vaccine could overcome the decreased vaccine respons in cirrhosis patients and offer strong protection against the virus, severe illness, and death from COVID-19.
Adding radiation therapy to systemic therapy for patients with advanced liver cancer can extend overall survival and delay tumor progression without compromising patients’ quality of life, a randomized phase III clinical trial shows.
The October issue of AJG highlights new clinical science and includes a supplement, ACG Monograph on GI Diseases and Endoscopy in Pregnancy & Postpartum Period, which includes recommendations for the care of pregnant patients with GI and liver diseases.
Mariam F. Eskander, MD, MPH, surgical oncologist at Rutgers Cancer Institute of New Jersey, the state’s leading cancer center only National Cancer Institute (NCI)-designated Comprehensive Cancer Center, together with RWJBarnabas Health, and assistant professor of surgery at Rutgers Robert Wood Johnson Medical School whose clinical expertise includes liver tumors, shares more information on liver cancer and excessive alcohol use.
RUDN University epidemiologists have reconstructed the history of hepatitis B and D viruses evolution in Yakutia (Russia). The investigation has established the course of evolution over the past fifteen hundred years. It turned out that a silent epidemic of hepatitis D continues in the region, and measures must be taken to stop it.
New advances around perfusion devices are changing the game by keeping transplant livers alive longer, allowing for transportation of longer distances. New technology also enhances marginal donor livers, keeping them stimulated and alive longer, and therefore making many more livers available for transplantation.
This in-person conference will provide groundbreaking insights on the technology and techniques around the use of preservation devices and examine the different strategies for successful perfusion/preservation of donor livers.
As people with HIV age, their risk of heart attack increases far more if they also have untreated hepatitis C virus, even if their HIV is treated, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH)—a type of fatty liver disease that might progress to cancer—is particularly prevalent among obese people.
Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.
After a rare disease caused organ failure, UC San Diego Heath transplant teams performed a heart, liver and kidney transplant on a patient. The surgery is a first for UC San Diego Health and a first in the nation to use three organs from a donor after circulatory death.
UHN’s Ajmera Transplant Centre and The Centre for Living Organ Donation announce today the launch of a new campaign, Great Actions Leave a Mark, www.greatactions.ca. The campaign showcases through artistic photos and video, the stories and scars (the mark) from 39 living organ donors and transplant recipients across Canada.
Children's Hospital Los Angeles is hosting the 26th annual meeting of the Society of Pediatric Liver Transplantation, a multidisciplinary, multicenter consortium focused on optimizing outcomes in pediatric liver transplantation through research, advocacy and dissemination of best practices in the field.
The September issue of AJG highlights new clinical science, including a potential therapy to improve IBS-C symptoms, reintroduction of infliximab for Crohn’s disease, and population-based data to examine incidence and mortality of certain GI and hepatology diseases.
The University of Miami Miller School of Medicine Division of Digestive Health and Liver Diseases shines not only for its commitment to patient care and published research, but also as a beacon for advancing the careers of female physicians. The division is celebrating the latter during September, which is the American Medical Association’s National Women in Medicine Month.
Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer—at an early enough stage that cure is possible. Their work was published online in the peer-reviewed journal Hepatology.
The American Association for the Study of Liver Diseases (AASLD) Foundation, the largest medical society supporter of liver disease research and training in the United States, today announced its combined investment of over $1.5 million in Research and Career Development Awards, Abstract Awards, Emerging Liver Scholars (ELS) Program for medical residents and its new Emerging Liver Advanced Practice Provider (APP) Program.
The 2022 award recipients — selected from a highly competitive applicant pool — demonstrate both exceptional aptitude and deep interest in liver disease research and treatment. Their work will further advance the mission of the AASLD Foundation and hepatology as a medical specialty.
In mouse studies, UC San Diego researchers find that excess alcohol consumption alters gut microbiome but latter is not directly or significantly linked to liver disease.
UT Southwestern will lead a multisite initiative funded by the National Cancer Institute (NCI) to identify biomarkers to improve risk assessment and early detection of hepatocellular cancer (HCC), the most common form of liver cancer, among patients with cirrhosis.
The August issue of The American Journal of Gastroenterology highlights new clinical science, including a brand new ACG clinical guideline for the diagnosis and treatment of patients with gastroparesis.
New research led by UCLA Jonsson Comprehensive Cancer Center investigators suggests that new technology in development may lead to a better way to detect early-stage hepatocellular carcinoma (HCC).
Data published in Cell Metabolism on liver cancer’s rapid growth which leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
Physicians and researchers from UK HealthCare's Transplant Center and the University of Kentucky Markey Cancer Center conducted a study of patients over the age of 70 with a type of liver cancer called hepatocellular carcinoma (HCC) and how the outcomes of ablative treatments compare to liver transplants. The findings were published in the May 2022 issue of the Journal of the American College of Surgeons.
People with sedentary lifestyles and unhealthy sleep behaviors could develop fatty liver disease, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
In mouse studies, UC San Diego researchers report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage.
Clinical advances include treating hematologic cancers with effective targeted therapies, circulating tumor DNA as a biomarker for recurrence with colorectal liver metastases, and using magnetic resonance imaging (MRI) to guide surgical decisions for patients with lateral pelvic lymph node metastases in rectal cancer. Laboratory findings offer new understanding of the pancreatic cancer immune microenvironment, melanoma cell states, TP53 mutation status in acute myeloid leukemia (AML), and potential targets for metastatic prostate cancer and GNAS-mutant colorectal cancer.
Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.
Treating liver cancer tumors to shrink them in order to allow the patient to qualify for a liver transplant leads to excellent 10-year post-transplant outcomes, according to new Mount Sinai research published in JAMA Surgery. The results validate current national policies around transplant eligibility.