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9-Dec-2018 11:00 AM EST
MD Anderson study shows key enzyme linked to therapy resistance in deadly lung cancer
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC).

1-Dec-2018 12:05 PM EST
More than half of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma in ZUMA-1 trial
University of Texas MD Anderson Cancer Center

A follow-up analysis of patients enrolled in a Phase I/II multi-center trial for diffuse large B-cell lymphoma (DLBCL) reported 51 percent of patients receiving an anti-CD19 chimeric antigen receptor (CAR T) called axi-cel were still alive two years post-treatment. The study, co-led by Sattva Neelapu, M.D., professor of Lymphoma & Myeloma at The University of Texas MD Anderson Cancer Center, reported its findings in the Dec. 2 online issue of The Lancet Oncology and during a presentation at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego.

27-Nov-2018 2:05 PM EST
App Helps Breast Cancer Survivors Improve Health After Treatment
Houston Methodist

Breast cancer survivors who used a smartphone app created at Houston Methodist consistently lost weight, largely due to daily, real-time interactions with their health care team via the mobile app.

Released: 30-Nov-2018 9:00 AM EST
Proposed study investigating use of atmospheric gas to lessen brain injury in survivors of cardiac arrest
University of Texas Health Science Center at Houston

Emergency medicine physicians at The University of Texas Health Science Center at Houston (UTHealth) are seeking community input about a proposed clinical trial assessing the efficacy of inhaling xenon, a medical gas, to mitigate brain injury and preserve cerebral function in cardiac arrest patients.

Released: 28-Nov-2018 10:05 AM EST
Umbilical Cord Blood Cells Studied for Preserving Brain Function in Infants with Congenital Diaphragm Disease
University of Texas Health Science Center at Houston

A new clinical trial at The University of Texas Health Science Center at Houston (UTHealth) is the first in the world to investigate whether infusing an infant’s own umbilical cord blood cells, or autologous cells, can protect the brain, mitigating the risk of neurodevelopmental challenges in babies with severe congenital diaphragmatic hernia (CDH).

Released: 27-Nov-2018 12:05 PM EST
Fatty Liver Disease
Houston Methodist

Millions of Americans have no idea that they have fatty liver disease. This growing problem will soon be the number one reason for liver transplantation, overtaking hepatitis C. Holiday overindulgence in alcohol and food could make the problem dramatically worse.

Released: 27-Nov-2018 11:05 AM EST
Peers choose MD Anderson’s Gershenwald, Hwu as new AAAS Fellows
University of Texas MD Anderson Cancer Center

Two leaders in the field of melanoma treatment – a surgeon and an oncologist – from The University of Texas MD Anderson Cancer Center have been named Fellows of the American Association for the Advancement of Science (AAAS).

Released: 20-Nov-2018 5:05 PM EST
Moderation and creativity hold key to happy, healthy Thanksgiving
University of Texas Health Science Center at Houston

The temptation to overindulge at Thanksgiving is immense, but before going overboard, it’s worth pausing and remembering you can eat, drink, and be merry – as well as healthy – over the holiday season.

Released: 20-Nov-2018 11:05 AM EST
Stand Up to Cancer funds innovative approach to pancreatic cancer
University of Texas MD Anderson Cancer Center

Research on a new way of deploying the immune system against pancreatic cancer, an exceptionally lethal cancer that has so far resisted new immunotherapies, will receive $1 million in initial funding from Stand Up to Cancer. The project led by researchers from The University of Texas MD Anderson Cancer Center and Baylor College of Medicine will collect T cells – the immune system’s targeted warriors -- from tumors, expand their number by the billions and then customize them to resist being shut down by a common substance that’s abundantly produced in tumor tissue

Released: 19-Nov-2018 11:05 AM EST
U.S. DOE approves HARC proposal under a non-competitive action to address flaring issues, solutions and technologies
Houston Advanced Research Center (HARC)

Flaring issues vary across the U.S. with complex regulatory, economic and infrastructure frameworks. A team comprised of researchers from the Houston Advanced Research Center (HARC) and the Research Partnership to Secure Energy for America (RPSEA) will evaluate the current state of technologies and regulatory and economic environments, to identify technical and economic solutions for further investigation and demonstration.

   
Released: 16-Nov-2018 5:05 PM EST
Take Care of Your Skin in the Winter Chill with Handy Hints From UTHealth
University of Texas Health Science Center at Houston

With temperatures dipping below freezing, consider the toll that frost is taking on your skin. The good news is experts from The University of Texas Health Science Center at Houston (UTHealth) can help keep your skin in tip-top condition as the winter weather takes hold.

Released: 15-Nov-2018 11:05 AM EST
FDA restrictions on e-cigarettes important step to protect the health of youth
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center applauds new actions announced today by the U.S. Food and Drug Administration (FDA) to limit the sale of most flavored electronic cigarettes (e-cigarettes) to age-restricted locations and require age-verification for online sales to lower the use of these products in children. In addition, the FDA plans to restrict the marketing of these products toward youth.

Released: 15-Nov-2018 11:05 AM EST
Project on improving lifesaving care for emergency trauma patients leads to pioneering clinical trial
University of Texas Health Science Center at Houston

Using an innovative quality improvement project to determine how to design an effective emergency trauma clinical trial, a team of surgeons at The University of Texas Health Science Center at Houston (UTHealth) was able to launch the first-ever study on a high-risk damage control surgery for critical abdominal injuries.

Released: 15-Nov-2018 9:00 AM EST
Houston Methodist Part of First Pilot in Nation to Bridge Electronic Gap for Automated Case Reporting to Public Health Agencies
Houston Methodist

In collaboration with the Houston Health Department and Epic (electronic medical records company), Houston Methodist is the first hospital system in eight U.S. pilot sites to successfully test and launch an approach to electronic case reporting (eCR) that can automatically send case reports directly from a hospital to public health agencies.

Released: 14-Nov-2018 10:05 AM EST
Investigational Drug Shows Promising Results in Phase II Study of Aggressive, Often Fatal Blood Disorder with No Approved Therapies
University of Texas MD Anderson Cancer Center

A Phase I/II study, led by investigators at The University of Texas MD Anderson Cancer Center, reports an investigational drug called tagraxofusp has demonstrated high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive – and often fatal bone marrow and blood disorder – for which there are no existing approved therapies.

Released: 13-Nov-2018 10:05 AM EST
Immunotherapy combination and chemotherapy show encouraging results in Phase II acute myeloid leukemia study
University of Texas MD Anderson Cancer Center

A triple therapy combining two immune checkpoint inhibitors (ICPIs) with the standard-of-care chemotherapy, a hypomethylating agent called azacitidine, has shown promising results for treatment of relapsed or refractory acute myeloid leukemia (AML), according to findings from a Phase II study at The University of Texas MD Anderson Cancer Center.

12-Nov-2018 6:20 AM EST
Fecal transplant effective against immunotherapy-induced colitis
University of Texas MD Anderson Cancer Center

For the first time, transplanting gut bacteria from healthy donors was used to successfully treat patients suffering from severe colitis caused by treatment with immune checkpoint inhibitors. The study from The University of Texas MD Anderson Cancer Center, which includes two patients, suggests fecal microbiota transplantation is worth investigating in clinical trials as a therapy for this common side effect of immunotherapy.

Released: 9-Nov-2018 12:05 PM EST
UTHealth leads race to demystify antibiotic resistance and win the war against superbugs
University of Texas Health Science Center at Houston

Antibiotic resistance is predicted to be the No. 1 cause of death in the world by 2050, but a team of scientists and physicians at The University of Texas Health Science Center at Houston (UTHealth) is determined to help stop this grave prediction from becoming a reality.

Released: 8-Nov-2018 4:05 PM EST
First-ever prostate cancer treatment uses gold nanoparticles to destroy tumorous cells
University of Texas Health Science Center at Houston

A small clinical trial using gold nanoparticles that act as tumor-seeking missiles on a mission to remove prostate cancer has begun at The University of Texas Health Science Center at Houston (UTHealth). It is the first trial of its kind in the world.

7-Nov-2018 9:00 AM EST
Combination chemotherapy and immunotherapy effective in Phase II leukemia study
University of Texas MD Anderson Cancer Center

A combination of the standard-of-care chemotherapy drug known as azacitidine, with nivolumab, an immune checkpoint inhibitor, demonstrated an encouraging response rate and overall survival in patients with relapsed or refractory acute myeloid leukemia (AML) according to findings from a Phase II study at The University of Texas MD Anderson Cancer Center.

30-Oct-2018 5:00 PM EDT
Minimally Invasive Surgery Associated with Worse Survival for Women with Cervical Cancer Compared to Open Hysterectomy
University of Texas MD Anderson Cancer Center

When comparing standard-of-care surgical options for women with early-stage cervical cancer, two studies led by researchers at The University of Texas MD Anderson Cancer Center discovered that minimally invasive radical hysterectomy is associated with higher recurrence rates and worse overall survival (OS), compared to abdominal radical hysterectomy.

Released: 31-Oct-2018 3:05 PM EDT
Virtual Program Successful in Linking Adult Protective Services, Geriatric Specialists
University of Texas Health Science Center at Houston

In its first year, an innovative virtual program has substantially increased mistreated elderly Texans’ access to elder mistreatment and geriatric experts with The University of Texas Health Science Center at Houston (UTHealth).

Released: 31-Oct-2018 10:30 AM EDT
Pioneering Culinary Dentistry Program Enters Halloween Spirit to Offer Fiendishly Healthy Options
University of Texas Health Science Center at Houston

Beheaded stuffed peppers, graveyard chocolate hummus and creepy crawly pumpkin bars were among the Halloween-themed treats created by students at The University of Texas Health Science Center at Houston (UTHealth) School of Dentistry who were learning how to cook as part of a new program in partnership with UTHealth School of Public Health.

23-Oct-2018 2:05 PM EDT
Suppression of DKK3 protein thwarts pancreatic tumor progression and prolongs survival
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have shed new light on why pancreatic tumors are so resistant to therapy.

Released: 24-Oct-2018 11:05 AM EDT
Dell Center for Healthy Living to launch statewide network to increase access to research
University of Texas Health Science Center at Houston

The Michael & Susan Dell Center for Healthy Living, part of The University of Texas Health Science Center at Houston (UTHealth), announced today a new plan to create a statewide network of researchers, decision-makers, and other key representatives that will give increased access to evidence-based solutions and data.

21-Oct-2018 11:00 AM EDT
RNA Thought to Spread Cancer Shows Ability to Suppress Breast Cancer Metastasis
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a form of RNA called metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) appears to suppress breast cancer metastasis in mice, suggesting a potential new area of therapeutic investigation. The findings, published in the Oct. 22 online issue of Nature Genetics, were surprising given that MALAT1, a long non-coding RNA (lncRNA), previously was described as a metastasis promoter.

20-Oct-2018 2:05 PM EDT
Study shows surgery, radiation extend survival of patients with limited metastatic lung cancer
University of Texas MD Anderson Cancer Center

Radiation or surgical removal of metastatic tumors provides a major survival advantage for lung cancer patients with minimal stage 4 disease who have not progressed after frontline chemotherapy, a study led by researchers from The University of Texas MD Anderson Cancer Center shows.

9-Oct-2018 5:00 PM EDT
Cancer Patients with Rare Deadly Brain Infection Treated Successfully with Off-the-Shelf Adoptive T-Cell Therapy in Clinical Trial
University of Texas MD Anderson Cancer Center

An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection sometimes observed in patients with cancer and other diseases in which the immune system is compromised. The study, led by Katy Rezvani, M.D., Ph.D., professor, Department of Stem Cell Transplantation and Cellular Therapy at The University of Texas MD Anderson Cancer Center, showed marked improvement in three PML patients infused with donor T cells targeting the BK virus. Findings were published in the Oct. 11 online issue of the New England Journal of Medicine.

7-Oct-2018 4:05 PM EDT
Neoadjuvant Combination Checkpoint Blockade Trial Yields High Response Rates for Patients with High-Risk Stage 3 Melanoma
University of Texas MD Anderson Cancer Center

The phase II study was led by researchers at The University of Texas MD Anderson Cancer Center. Results of the study, the first randomized neoadjuvant clinical trial of immune checkpoint blockade for melanoma patients, are reported in Nature Medicine.

3-Oct-2018 3:50 PM EDT
MD Anderson and Cyclacel Pharmaceuticals Announce Strategic Alliance to Study Novel Cyclacel Medicines in Hematological Malignancies
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and Cyclacel Pharmaceuticals, Inc., today announced a three-year strategic alliance agreement that will enable clinical evaluation for safety and efficacy of three Cyclacel medicines in patients with hematological malignancies, including chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and other advanced leukemias.

Released: 2-Oct-2018 4:15 PM EDT
MD Anderson Immunologist Jim Allison Awarded Nobel Prize
University of Texas MD Anderson Cancer Center

T cell discoveries led to game-changing treatment revolutionizing cancer care

Released: 1-Oct-2018 2:05 PM EDT
New integrated, outpatient program created to combat mental illness, homelessness
University of Texas Health Science Center at Houston

To help break the cycle of mental illness, addiction and homelessness, The University of Texas Health Science Center at Houston (UTHealth) has launched a new integrated, trauma-informed behavioral health program for treatment and recovery support.

26-Sep-2018 4:55 PM EDT
Vaccine, Anti-PD1 Drug Show Promise Against Incurable HPV-Related Cancers
University of Texas MD Anderson Cancer Center

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

Released: 27-Sep-2018 9:00 AM EDT
Houston Methodist Adds Depth to Cancer Biology, Surgical Oncology, and Cancer Prevention and Control Programs
Houston Methodist

Houston Methodist Cancer Center has expanded its basic cancer research program, cancer prevention and control efforts, and surgical oncology services with the addition of two national recruits.

Released: 26-Sep-2018 2:05 PM EDT
UTHealth part of NIH-funded genome center to accelerate precision medicine discoveries
University of Texas Health Science Center at Houston

The University of Texas Health Science Center at Houston (UTHealth) will be part of a new genome center, one of just three created nationally with $28.6 million in funding from the All of Us Research Program of the National Institutes of Health (NIH).

Released: 24-Sep-2018 4:05 PM EDT
Poziotinib Maintains High Response Rate Against Harmful Lung Cancer Mutation
University of Texas MD Anderson Cancer Center

A drug revived by researchers at The University of Texas MD Anderson Cancer Center continues to provide unprecedented response rates among stage 4 non-small cell lung cancer patients with genetic mutations that have previously defied treatment.

Released: 21-Sep-2018 4:05 PM EDT
UTHealth and Astros lead charge against Huntington’s disease and help patients have a ball
University of Texas Health Science Center at Houston

Living with Huntington’s disease can often feel like an endless battle, but patients and their families had the time of their lives watching the Houston Astros in action at Minute Maid Park.

Released: 21-Sep-2018 3:05 PM EDT
MD Anderson hosts Biden Cancer Community Summit
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today joined with more than 450 communities and institutions across the country in hosting a Biden Cancer Community Summit, organized under the charge of the Biden Cancer Initiative. The Summit aims to encourage an ongoing dialogue about opportunities to make significant advances in cancer research, prevention, diagnosis and care.

Released: 11-Sep-2018 4:05 PM EDT
Study Launched on Probiotics to Help Treat GI Issues and Improve Aberrant Behavior in Autistic Children
University of Texas Health Science Center at Houston

A professor at UTHealth in Houston is testing the hypothesis that probiotics can help improve gastrointestinal symptoms of children with autism spectrum disorder (ASD).

Released: 11-Sep-2018 8:00 AM EDT
MD Anderson immunotherapy expert Sharma wins Coley Award
University of Texas MD Anderson Cancer Center

Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology at The University of Texas MD Anderson Cancer Center, has been recognized for her innovative work understanding factors that enhance and hinder cancer immunotherapy. Sharma will receive the William B. Coley Award for Distinguished Research in Tumor Immunology, awarded annually by the Cancer Research Institute (CRI), at an annual meeting co-sponsored by CRI in New York Sept. 30 to Oct. 3.

7-Sep-2018 8:00 AM EDT
Study Links BAP1 Protein to Tumor Suppression in Kidney, Eye, Bile Duct and Mesothelioma Cancers
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology.

Released: 27-Aug-2018 10:05 AM EDT
Significant Dialysis Development
Houston Methodist

A new device allows surgeons to create an access point for dialysis patients using a minimally-invasive approach. This might help the more than 470,000 currently on dialysis.

Released: 23-Aug-2018 11:05 AM EDT
Research Reveals Dangerous Midlife Switch of Ditching Activity to Sit Still
University of Texas Health Science Center at Houston

People are falling into a trap of greater inactivity during middle age, according to new research from The University of Texas Health Science Center at Houston (UTHealth), which calls for its findings to be considered in future national physical activity guidelines.

Released: 23-Aug-2018 10:05 AM EDT
Will We Be Ready for the Next Harvey?
Houston Advanced Research Center (HARC)

Public program featuring thought leaders on the topic of funding community resilience in the face of more acute and chronic natural disasters.

20-Aug-2018 2:05 PM EDT
Combination Immunotherapy Shrinks Melanoma Brain Metastases
University of Texas MD Anderson Cancer Center

Combination immunotherapy shrank melanoma that has spread to the brain in more than half of the patients in a clinical trial reported in the New England Journal of Medicine led by an investigator at The University of Texas MD Anderson Cancer Center.



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