By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic changeone in a gene involved in muscle formationin five of the tumors.
ASCB announces East and West Coast dates for summer biotech course, scholarships
Around 40-60% of healthy adults carry around the fungus Candida albicans in their mouth or guts; in immunocompromised people, however, this normally harmless cohabitant becomes a deadly pathogen. A report in the journal GENETICS describes the genomes of three Candida albicans strains isolated from the barks of oak trees in an ancient wood pasture, providing genetic evidence that this yeast can live on plants for extended periods of time.
For nanomedicine to achieve the envisioned breakthroughs in disease treatment, scientists must learn why the immune system often responds inhospitably to these therapies. An NIH-funded team at the University of Colorado (UC) has assembled a clearer picture of the molecular activity that occurs when nanoparticles injected into the body are marked for immune system attack.
Salisbury University has signed the first agreements with prospective industrial hemp growers under a new Maryland Department of Agriculture pilot program to legalize the crop with a university research component.
The Johns Hopkins Center for Communication Programs (CCP) has been awarded the U.S. Agency for International Development’s newest five-year, $35 million global knowledge management project. CCP is based at the Johns Hopkins Bloomberg School of Public Health.
Edward J. Benz Jr., MD, joins the Johns Hopkins School of Nursing (JHSON) Nursing Advisory Board bringing extensive experience and perspective as a leader in academia, internal medicine, mentorship, and research. He is the Richard and Susan Smith Distinguished Professor of Medicine and Professor of Pediatrics and Genetics at Harvard Medical School, President and CEO Emeritus for the Dana-Farber Cancer Institute and Director Emeritus of the Dana Farber/Harvard Cancer Center.
In observance of Rare Disease Day, February 28, the American Society for Biochemistry and Molecular Biology offers these news tips on recent research into rare diseases.
Precision medicine is a focus of ongoing debate. In an environment of limited research funds, there are those who believe that precision medicine should be funded because it will improve population health, and those who feel that it shouldn’t, because it won’t. In a viewpoint published Jan. 28 in the Journal of Clinical Investigation, experts at Johns Hopkins call for a redefinition of precision medicine to ensure its success, and propose a new approach.
A small, retrospective study has found that, in patients with particular pancreatic duct lesions, the presence of an inherited mutation in a pancreatic cancer susceptibility gene may increase the patients’ risk of developing pancreatic cancer. To verify these results and learn more about the development of this deadly cancer, the researchers recommend more genetic studies. Their hope—in line with the goals of precision medicine—is to eventually find a better way to guide patient care, dividing patients, for example, into those who need regular screening versus immediate surgery or other early interventions.
Richard W. Thomas, MD, DDS, president of the Uniformed Services University of the Health Sciences, will be inducted into the West Virginia University Academy of Distinguished Alumni (www.alumni.wvu.edu/give-back/awards/academy-of-distinguished-alumni), joining notable WVU graduates like best-selling author Stephen Coonts, comedic actor Don Knotts, NBA star Jerry West, and NASA astrophysicist Dr. Katherine Weaver.
In a study of older people with no clinical diagnosis or signs of dementia when hospitalized to repair hip fractures, Johns Hopkins researchers say they found biomarkers of Alzheimer’s disease in most of the patients’ spinal fluid samples. The researchers say results of their study add to evidence that brain alterations that lead to poor balance in older people may underpin both increased risk of hip-fracturing falls and Alzheimer’s disease, and that hip fracture itself may therefore serve as a first sign of undiagnosed disease.
The American Institute of Physics announced today that its Board of Directors has elected astrophysicist David J. Helfand as its new chair. In his new role, Helfand will be responsible for providing leadership to AIP's Board of Directors and will guide their efforts overseeing governance, policy and corporate strategy for the Institute, a mission-driven nonprofit organization, devoted to advancing, promoting and serving the physical sciences for the benefit of humanity.
A new study by Johns Hopkins Bloomberg School of Public Health researchers found that U.S.-based patient advocacy organizations received a disproportionate amount of contributions made by the world’s 10 largest pharmaceutical companies in 2016.
Vale, an HHMI investigator at the University of California, San Francisco, will serve as the second executive director of the Ashburn, Virginia-based biomedical research center.
Bioengineers are designing aortic heart valve replacements made of polymers rather than animal tissues. The goal is to optimize valve performance and enable increased use of a minimally-invasive method for valve replacement over the current practice of open heart surgery.
A new method of increasing the reactivity of ultrathin nanosheets, just a few atoms thick, can someday make fuel cells for hydrogen cars cheaper, finds a new Johns Hopkins study.
A new review of more than 140 studies explores the physiological dangers that climate change will likely have on animal life, including humans. The review is published in the journal Physiology.
Roisin Connolly, M.B.B.Ch., M.D., associate professor of oncology Credit: Johns Hopkins Kimmel Cancer Center
Ilinois could reduce the number of people killed each year by gun violence by implementing ten policies supported by available research, according to a new report authored by researchers at the Johns Hopkins Center for Gun Policy and Research. The center is based at the Johns Hopkins Bloomberg School of Public Health.
Johns Hopkins School of Nursing (JHSON) Professor and Anna D. Wolf Chair Jacquelyn Campbell, PhD, RN, FAAN, will present on violence against women at the Sigma Theta Tau International (Sigma) event—“Precursors to Violence: Identifying, De-escalating, and Reducing Women’s Risks.” The event is a parallel meeting to the 63rd session of the United Nations Commission on the Status of Women, one of the most influential global conferences to furthering women’s rights.
The dynamic five-day Meeting provides attendees with opportunities to share their latest unpublished findings and learn the newest emerging techniques and applications.
A four-week interdisciplinary pain management program for worker’s compensation patients with chronic pain significantly reduced their opioid and benzodiazepine use.
People with two autoimmune diseases, rheumatoid arthritis (RA) and Sjögren’s syndrome, are at an increased risk for developing carpal tunnel syndrome (CTS), and should be screened for CTS and made aware of this risk.
“Canada to Key West,” a 2,350-mile walk to raise awareness about the impact of increasingly frequent extreme weather events will start on June 21, 2019, the day of the summer solstice.
People with West Nile neuro-invasive disease, a severe and systemic illness caused by infection with the mosquito-borne West Nile virus, can have significant functional and cognitive declines and may benefit from individualized, brain injury-specific rehabilitation as a cornerstone of their recovery.
Smokers are at high risk for low back pain, and also have higher rates of healthcare utilization and opioid use, and physicians should ask these patients about other comorbidities that may make their pain treatment more difficult.
A new virtual reality physical activity intervention may be effective for people with chronic low back pain who avoid activity because of fear, helping them to become physically active once again.
Golfers with knee osteoarthritis who walk the golf course rather than riding in a cart experience increased joint inflammation, but gain significant cardiovascular benefits from the aerobic activity.
After just one episode of vaping, or using an e-cigarette device, a 17-year-old was hospitalized in Tennessee with acute respiratory distress syndrome (ARDS), cardiopulmonary collapse, shock stroke.
Blood alcohol levels may have a specific dose-dependent effect on treatment outcomes for people with traumatic brain injury. This effect is significant at an intermediate blood alcohol level even when multiple variables are taken into account.
American football players develop chronic traumatic encephalopathy, or CTE, after only playing football at the high school level, with higher rates of CTE associated with higher levels of play.
A new electromyography biofeedback device that is wearable and connects to novel smartphone games may offer people with incomplete paraplegia a more affordable, self-controllable therapy to enhance their recovery.
Algorithms using data from antibody signatures in peoples’ blood may enable scientists to assess the size of cholera outbreaks and identify hotspots of cholera transmission more accurately than ever, according to a study led by scientists at the Johns Hopkins Bloomberg School of Public Health.
Reporters and bloggers are invited to attend Nutrition 2019, the flagship meeting of the American Society for Nutrition. The meeting will be held June 8-11, 2019 at the Baltimore Convention Center.
When a stream of charged particles known as the solar wind careens onto the Moon's surface at 450 kilometers per second (or nearly 1 million miles per hour), they enrich the Moon's surface in ingredients that could make water, NASA scientists have found.
A team of astronomers using the Hubble Space Telescope, and older Voyager 2 spacecraft data, have studied the origin of the smallest known moon orbiting the planet Neptune. The moon, which was discovered in 2013 and has now received the official name Hippocamp, may actually be a fragment broken from its larger neighboring moon Proteus.
Public health experts and policymakers will gather at the Johns Hopkins Bloomberg School of Public Health on Monday, February 25 to discuss policies that could reduce maternal deaths in the United States, especially among black women. The event will also honor Dr. Shalon Irving, a Johns Hopkins Bloomberg School of Public Health alumna and Centers for Disease Control and Prevention (CDC) epidemiologist who passed away unexpectedly in 2017, just three weeks after giving birth.
A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vision. Increased melanin could help protect people with the condition against the sun’s UV rays and promote the development of normal vision.
Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.
In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.
The Chesapeake Writers’ Conference hosts writers at all levels of experience for a rich week of lectures, craft talks, readings, and panel discussions, as well as daily workshops in fiction, poetry, creative nonfiction, translation, and screenwriting. Workshops are led by a variety of writers at the top of their field, such as Angela Pelster, winner of the Great Lakes Colleges Association “New Writer Award in Nonfiction;” Patricia Henley, a finalist for the National Book Award; and Elizabeth Arnold, a Whiting Writer’s Award winner.
Several students and two faculty are traveling to the West Indies this week for the Antigua and Barbuda Governor General’s Seminar on Historic Preservation as part of a recent partnership between St. Mary’s College of Maryland and the Office of the Governor General of Antigua and Barbuda.
A study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that the Food and Drug Administration (FDA) and manufacturers did not take action when evidence emerged that potentially lethal fentanyl products were being inappropriately prescribed to patients.
A new survey examining U.S. consumer attitudes and behaviors related to food date labels found widespread confusion, leading to unnecessary discards, increased waste and food safety risks. The survey analysis was led by researchers at the Johns Hopkins Center for a Livable Future (CLF), which is based at the Johns Hopkins Bloomberg School of Public Health.
Renowned scientists including Nobel laureates, research pioneers and celebrated educators will convene at the Experimental Biology (EB) 2019 meeting, to be held April 6–9 in Orlando. Bringing together more than 12,000 life scientists in one interdisciplinary community, EB showcases the latest advances in anatomy, biochemistry, molecular biology, investigative pathology, pharmacology and physiology.
Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system’s ability to fight melanoma in mice. The agents, dubbed s-DAB-IL-2 and s-DAB-IL-2(V6A), comprise a regulatory protein called human interleukin-2 fused to chemically modified portions of diphtheria toxin.
Study: Adolescent Female Blood Donors At Risk For Iron Deficiency And Associated Anemia 02/19/2019 AddThis Sharing Buttons Share to Facebook Share to TwitterShare to EmailShare to PrintShare to More New public health measures could help protect this vulnerable population, authors say Credit: iStock Female adolescent blood donors are more likely to have low iron stores and iron deficiency anemia than adult female blood donors and nondonors, which could have significant negative consequences on their developing brains, a new study led by Johns Hopkins researchers suggests. Based on these findings, the authors propose a variety of measures that could help this vulnerable population.
The American Society for Cell Biology (ASCB) and 52 other leading academic and professional societies announced the creation the Societies Consortium on Sexual Harassment in STEMM at a panel discussion during the AAAS Annual Meeting on February 15, 2019.
Researchers using proteomics and mouse genetics to understand the protein makeup of HDL find that it's a complicated mix of inherited and environmental factors. Their work may help understand HDL's functions beyond carrying cholesterol.
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