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Released: 21-Feb-2019 11:05 AM EST
Current Tools Have Low Accuracy for Predicting Delayed Ischemia after Aneurysmal Subarachnoid Hemorrhage
Wolters Kluwer Health: Lippincott

Both CT angiography and transcranial Doppler have limited accuracy in detecting cerebral vasospasm and predicting delayed cerebral ischemia (DCI) in patients with subarachnoid hemorrhage (SAH) due to ruptured aneurysm, reports a study in the inaugural edition of Critical Care Explorations, the official open-access journal of the Society of Critical Care Medicine (SCCM). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 21-Feb-2019 11:05 AM EST
Price Transparency Helps Arizona Health System Achieve Financial Turnaround
Wolters Kluwer Health: Lippincott

Efforts to understand costs and openly share information on healthcare prices played a key role in a major Arizona health system's successful turnaround from a financial crisis, according to a feature article in the Spring issue of Frontiers of Health Services Management, an official publication of the American College of Healthcare Executives (ACHE). This journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 21-Feb-2019 8:05 AM EST
The Medical Minute: Varicose veins unlikely to develop into blood clots
Penn State Health

Similar to leaky pipes, veins, as they return blood to the heart, sometimes fail to close completely. They stretch out and subsequently leak near the surface of the skin, creating spider or varicose veins that may cause discomfort.

Released: 20-Feb-2019 10:25 AM EST
Integrating Heart Disease and Cancer Care Could Reduce Overall Health Care Costs, According to Researchers
National Comprehensive Cancer Network® (NCCN®)

Study in JNCCN finds coronary artery disease costs increase dramatically in patients who are diagnosed with cancer.

Released: 20-Feb-2019 8:05 AM EST
Health-Related Google Searches Double in the Week Before ER Visits
Perelman School of Medicine at the University of Pennsylvania

Patients were found to often be willing to share their Google search histories with medical researchers, revealing that many do searches on their health concerns long before deciding to go to the hospital.

15-Feb-2019 9:40 AM EST
Children on the Autism Spectrum with Co-Occurring ADHD Symptoms Lag Behind in Key Measures of Independence and Communication
Children's Hospital of Philadelphia

A pair of new studies has provided new insight into the challenges faced by children on the autism spectrum who exhibit symptoms of attention deficit/hyperactivity disorder (ADHD). According to the findings from researchers at Children’s Hospital of Philadelphia (CHOP), these children have difficulty with adaptive behavior, a key measure of independence.

Released: 18-Feb-2019 4:05 PM EST
Researchers Key to Advance Care Planning With Cancer Clinical Trial Patients
University of Pennsylvania School of Nursing

Cancer clinical trials are an important option for patients with cancer. Yet, once a trial ends, patients still need care plans. Little is known at what point during clinical trial transitions to initiate advance planning discussions or how to educate research teams to communicate with and prepare patient-participants and their families for the next steps after they leave a cancer clinical trial.

Released: 18-Feb-2019 3:05 PM EST
Temperatures Rising: Patients Taking Diuretics May See More Benefit by Upping Potassium Intake During Warmer Weather
Perelman School of Medicine at the University of Pennsylvania

Patients taking diuretics are often at risk for low potassium levels, which can put patients at an increased risk of death from cardiac arrhythmias or other causes. But researchers from the Perelman School of Medicine at the University of Pennsylvania found that taking prescription potassium supplements can reduce these patients’ risk by nearly 10 percent as daily outdoor temperatures increase—a time when patients may be at highest risk due to loss of potassium while sweating. These findings are detailed in a study published today in BMJ Open.

15-Feb-2019 4:05 PM EST
Specialized Lung Cells Appear Very Early in Development
Children's Hospital of Philadelphia

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. Investigating the fetal signaling pathways active in the biological events by which alveoli form may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.

15-Feb-2019 1:00 PM EST
Mapping Brain Circuits in Newborns May Aid Early Detection of Autism
Children's Hospital of Philadelphia

A new map of newborn babies’ brains offers details of structure that will provide a new reference for researchers studying both typical brain development and neurological disorders. Using noninvasive, 20-minute MRI scans, researchers have revealed some of the complex and precisely organized brain architecture that emerges as the brain reshapes itself during the third trimester of pregnancy.

15-Feb-2019 4:05 PM EST
Penn Medicine and CHOP Study Finds that Fetal Signaling Pathways May Offer Future Targets for Treating Lung Injury
Perelman School of Medicine at the University of Pennsylvania

A new animal study describes how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life. Investigating the fetal signaling pathways active in this biological event may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.

18-Feb-2019 11:00 AM EST
New Insight Into the Balance Between the Tumor-suppressive and Tumor-promoting Effects of Cellular Senescence
Wistar Institute

Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules.

   
Released: 14-Feb-2019 3:05 PM EST
Immune Profiling: A New Opportunity for Drug Development
Perelman School of Medicine at the University of Pennsylvania

Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

Released: 14-Feb-2019 2:05 PM EST
Single Word Most Associated with Negative Hospital Reviews on Yelp is 'Told'
Perelman School of Medicine at the University of Pennsylvania

A Penn Medicine research team found that the word “told” was tied to almost 20 percent of poor reviews

Released: 14-Feb-2019 2:05 PM EST
When Research Participation Pays, Some People Lie, Penn Study Suggests
Perelman School of Medicine at the University of Pennsylvania

Offering compensation can be an important tactic to attract potential participants for enrollment in research studies, but it might come at a cost. A new study conducted by researchers in the Perelman School of Medicine at the University of Pennsylvania found that up to 23 percent of respondents lied about their eligibility to participate in a survey when offered payment, even small amounts.

Released: 14-Feb-2019 1:05 PM EST
Neural processing with trauma and adversity interact to increase core symptom of PTSD
Elsevier

Lifetime adversity and increased neural processing during a traumatic event combine to increase the frequency of intrusive traumatic memories and the distress they cause, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Released: 14-Feb-2019 10:15 AM EST
The Medical Minute: Helping caregivers address mental health concerns
Penn State Health

Caregiver jobs often come loaded with pressures. In fact, caregivers face a higher risk of developing a mental health disorder because of the stress that can accompany taking care of others.

Released: 14-Feb-2019 10:00 AM EST
Combination of T Cell Therapy and Targeted Therapy as a Novel Strategy for Therapy-resistant Melanoma with Mutations in the BRAF Gene
Wistar Institute

Collaborative research by The Wistar Institute and Moffitt Cancer Center has demonstrated that BRAF targeted therapies render resistant melanoma more sensitive to the attack of killer T cells.

   
Released: 13-Feb-2019 12:05 PM EST
In Defense of Millennials, the Global Generation
Perelman School of Medicine at the University of Pennsylvania

The word “millennial” isn’t exactly a compliment these days. The problem is, all the criticisms out there – “they’re too picky!” or “they’re entitled!” or “they spend all their money on lattes and avocado toast!” – have left it mostly with a negative connotation and rarely a positive one. Any praise for those born between 1981 and 1996 seems to be quickly drowned out by the headlines, memes, and social media posts reinforcing the same old stereotypes of an entire generation. But, in all fairness, millennials are also known to be altruistic, ambitious, and passionate about social injustices, more so than previous generations, many have argued. A USA Today article even described them as the most civic-minded generation in over half a century.

Released: 13-Feb-2019 10:30 AM EST
Drug-Resistant TB Cured with New Approaches in Conflict-Affected Region
Health Sciences at the University of Pittsburgh

A high proportion of multidrug-resistant tuberculosis (TB) cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of Congo.

Released: 13-Feb-2019 10:20 AM EST
New Book from Sociologist Daniel Laurison Explores the ‘Class Ceiling’
Swarthmore College

In his new book, The Class Ceiling: Why it Pays to Be Privileged, Assistant Professor of Sociology Daniel Laurison '99 investigates the ambiguities of meritocracy in white-collar workers’ salaries in the United Kingdom.

Released: 12-Feb-2019 11:30 AM EST
Annual 2019 Diversity and Inclusion Conference, sponsored by Temple University, returns to Philadelphia
Temple University

The 2019 Diversity & Inclusion Conference, held March 25-26 in Philadelphia, is an open forum to explore and exchange insights about diversity and inclusion (D&I) best practices for CEOs, diversity officers, educators, corporate leaders and government officials.

Released: 11-Feb-2019 3:00 PM EST
Researchers Identify Brain Protein Crucial to Recovery from Stroke
Health Sciences at the University of Pittsburgh

Researchers at the University of Pittsburgh School of Medicine have identified a brain protein at the root of how the brain recovers from stroke. The finding offers a promising avenue for developing therapies that could work even when given beyond the first few hours after a stroke.

8-Feb-2019 4:05 PM EST
For the First Time, Scientists ‘See’ Dual-Layered Scaffolding of Cellular Nuclei
Health Sciences at the University of Pittsburgh

Using super-sensitive microscopic imaging, a team of scientists made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish through narrow openings without springing a leak.

Released: 11-Feb-2019 12:05 PM EST
Potent marijuana edibles can pose a major unrecognized risk to patients with cardiovascular disease
Elsevier

Philadelphia, February 11, 2019 - As marijuana legalization sweeps North America, use of the substance has been on the rise, and the public's attitude is shifting. An increasing number of people believe that "weed" is the safest recreational drug, one that carries health benefits that outweigh its risks.

Released: 11-Feb-2019 11:00 AM EST
Federal Funding Fueled Growth of Wistar Science in 2018
Wistar Institute

The Wistar Institute announces that it was awarded more than $16M in federal research funds in support of its groundbreaking research in cancer, immunology and infectious diseases.

   
5-Feb-2019 4:10 PM EST
Engineered DNA Vaccine Protects Against Emerging Mayaro Virus Infection
Wistar Institute

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.

   
4-Feb-2019 8:00 AM EST
Prior Dengue Infection Protects Against Zika
Health Sciences at the University of Pittsburgh

The higher a person’s immunity to dengue virus, the lower their risk of Zika infection, an international team of scientists led by the University of Pittsburgh Graduate School of Public Health, Yale School of Public Health and University of Florida report today in the journal Science.

   
Released: 6-Feb-2019 2:05 PM EST
In Their DNA: Rotator Cuff Stem Cells More Likely to Develop into Fat Cells
Wolters Kluwer Health: Lippincott

Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Released: 6-Feb-2019 2:05 PM EST
The Medical Minute: Performing artists must protect their bodies like athletes
Penn State Health

Whether amateur or professional, performing artists have unique health needs specific to their art form.

Released: 6-Feb-2019 8:05 AM EST
How Fibrosis Develops in Butterfly Syndrome Patients
Thomas Jefferson University

Researchers have pinpointed how fibrosis develops in butterfly syndrome patients. The discovery points to a potential treatment for the debilitating complication.

Released: 5-Feb-2019 11:05 AM EST
Investing in Culture of Health Reduces Employee Health Risks
Wolters Kluwer Health: Lippincott

Companies that improve their "culture of health" realize some important benefits, including reductions in employee health risk factors, medical visits, prescription drug use, and healthcare costs, reports a study in the February Journal of Occupational and Environmental Medicine.

Released: 5-Feb-2019 8:05 AM EST
Penn State's Yamamoto to Use NSF CAREER Award to Improve Nanoengineered Materials in Aircraft
Penn State College of Engineering

Namiko Yamamoto, assistant professor of aerospace engineering at Penn State, will advance knowledge about the effective integration of polymer nanocomposites, consisting of carbon nanotubes, into hierarchically structured materials in transport vehicles for improved multifunctional properties, thanks to a National Science Foundation Early Career award.

31-Jan-2019 4:05 PM EST
Diversity in the CD4 Receptor Protects Chimpanzees from Infection by AIDS-like Viruses
Perelman School of Medicine at the University of Pennsylvania

An international team of collaborators found that the CD4 surface protein, which is used by HIV and SIV as the receptor to enter immune cells, is highly variable among wild chimpanzees.

Released: 4-Feb-2019 2:05 PM EST
Wolters Kluwer to Publish Journal of Psychosocial Oncology Research and Practice
Wolters Kluwer Health: Lippincott

Wolters Kluwer, Health announced today that the Journal of Psychosocial Oncology Research & Practice, the newest journal of the International Psycho-Oncology Society (IPOS), will be published under the Lippincott portfolio.

Released: 4-Feb-2019 2:05 PM EST
Leary Appointed Penn Nursing’s First Director of Innovation
University of Pennsylvania School of Nursing

In this role, Marion Leary, MSN, MPH, RN FAHA, will design and execute innovation programs and projects through Penn Nursing’s Office of Nursing Research (ONR) and will work to keep the School at the forefront of innovation in nursing. The appointment was effective February 1, 2019.

Released: 4-Feb-2019 12:30 PM EST
Saint Joseph’s University Bioethicist Calls for Safe Injection Sites; Proposes Customized Model for Philadelphia
Saint Joseph's University

University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.

Released: 4-Feb-2019 12:05 PM EST
Thyroid cancer incidence associated with malpractice climate
Penn State Health

The incidence of thyroid cancer was associated with malpractice payouts in a recent study by Penn State Cancer Institute researchers. Because thyroid cancer is not usually fatal, the findings suggest that physicians sometimes offer unnecessary testing to avoid being sued.

Released: 4-Feb-2019 11:45 AM EST
Potential to Better Treat Mesothelioma Revealed by Precision Medicine Research
Sbarro Health Research Organization (SHRO)

Researchers have successfully identified two genetic markers for potentially effective treatment of Mesothelioma, an orphan disease most commonly associated with asbestos exposure, and for which few treatments exist.

31-Jan-2019 3:05 PM EST
On World Cancer Day, National Comprehensive Cancer Network Announces National Endorsements for Guidelines to Improve Cancer Care in Sub-Saharan Africa
National Comprehensive Cancer Network® (NCCN®)

The National Comprehensive Cancer Network® (NCCN®) announces formal endorsements from the governments of Ethiopia, Nigeria, and Tanzania for the NCCN Harmonized Guidelines™ for Sub-Saharan Africa, while joining cancer leaders across the globe to raise awareness and take action for World Cancer Day on February 4.

Released: 1-Feb-2019 4:55 PM EST
Researchers Find Overdose Deaths Are Likely to Increase with ‘Changing Nature’ of Opioid Epidemic
Penn State College of Engineering

The opioid epidemic could be responsible for 700,000 overdose deaths in the United States between 2016 and 2025, according to a new study published today in JAMA Network Open.

   
Released: 1-Feb-2019 2:05 PM EST
Disappearing into the sea
Penn State College of Engineering

The remote town of Barrow, Alaska, home to more than 4,000 people, touts picturesque views of the Arctic Ocean as well as an unparalleled connection to the Alaskan wild, but underneath its stunning beauty lies a major global crisis – permafrost coastal erosion – causing Barrow to gradually slip into the sea.

28-Jan-2019 9:35 AM EST
To Sleep, Perchance to Heal: A Newly Discovered Gene Governs the Need for Slumber When Sick
Perelman School of Medicine at the University of Pennsylvania

In a study of over 12,000 lines of fruit flies, researchers from the Perelman School of Medicine at the University of Pennsylvania have found a single gene, called nemuri, that increases the need for sleep.

Released: 31-Jan-2019 12:05 PM EST
The Medical Minute: Living donors may benefit transplant patients
Penn State Health

For a patient awaiting a new organ – namely a liver or kidney – living donation provides a viable alternative and can often shorten a recipient’s wait time.

Released: 31-Jan-2019 11:40 AM EST
United Arab Emirates Ministry of Health and Prevention Highlights Children's Hospital of Philadelphia Breakthroughs at Arab Health 2019
Children's Hospital of Philadelphia

As part of a longstanding partnership with the UAE’s Ministry of Health and Prevention, Children’s Hospital of Philadelphia, a global leader in pediatric healthcare, exhibited some of its leading medical breakthroughs in the Ministry booth at the annual Arab Health Exhibition and Congress, in the Dubai International Convention and Exhibition Centre.

29-Jan-2019 1:30 PM EST
Commonly Used Anti-Rejection Drug Could be Repurposed to Treat Some Liver Cancers
Health Sciences at the University of Pittsburgh

Research in animal models suggest that liver cancers with a mutation in the β-catenin gene could respond to treatment with rapamycin, a commonly used immunosupressant.

Released: 30-Jan-2019 5:05 PM EST
Ramiah’s story: How patient care and medical innovation helped a child born without a trachea
Penn State Health

Patient being discharged today after spending the first 13 months of her life in the hospital

Released: 30-Jan-2019 11:40 AM EST
Engineering confidence: 'Build Night' offers hands-on making opportunities
Penn State College of Engineering

On January 14, more than 65 female engineering students attended the first spring 2019 Build Night and completed their first training for and used the machinery often needed to create design projects.

   
Released: 30-Jan-2019 11:05 AM EST
What Causes Aging of the Upper Lip? Loss of Volume, Not Just 'Sagging'
Wolters Kluwer Health: Lippincott

Plastic surgeons have long debated the mechanisms aging-related changes in the face: Are they related more to "deflation" or "sagging"? A new study helps settle the debate, showing significant loss of volume in the upper lip in older adults, reports the February issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).



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