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New research lays foundation for upcoming clinical trial for patients with epidermolysis bullosa

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Two large national studies show that patient safety was unaffected and residents showed no signs of chronic sleep loss regardless of shift length.

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Researchers at The Wistar Institute have created a drug candidate for cancers associated with Epstein-Barr Virus (EBV), the virus that causes infectious mononucleosis.

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When cancer spreads to another organ, it most commonly moves to the liver, and now researchers at the Abramson Cancer Center of the University of Pennsylvania say they know why.

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Between 2004 and 2017, dog-walking-related fractures in people 65-or-older more than doubled

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Laws that require landlords to disclose bed bug infestations help combat the spread of the insects and protect the health of potential tenants. According to a new study, these laws also lead to cost savings, on average, for landlords within five years. Researchers in the Perelman School of Medicine at the University of Pennsylvania published their findings today in Proceedings of the National Academy of Sciences (PNAS).

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More than 1,500 cancer care professionals are meeting in Orlando, Florida, March 21-23, for the NCCN 2019 Annual Conference, presented by the National Comprehensive Cancer Network® (NCCN®)—an alliance of 28 leading cancer centers.

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Recent research suggests heart attacks are becoming more common among women of younger ages. For decades, little was understood about SCAD -- the leading cause of pregnancy-associated heart attacks.

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Automated programs can identify which sick infants in a neonatal intensive care unit have sepsis hours before clinicians recognize the life-threatening condition. A study team tested machine-learning models in a NICU population, drawing only on routinely collected data available in electronic health records.

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For patients undergoing "tummy tuck" surgery (abdominoplasty), satisfaction with the aesthetic outcome is the main factor affecting whether they write a positive or negative online review for their plastic surgeon, reports the March issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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While the proportion of women entering plastic surgery residency programs has increased in recent years, numbers of Black and Hispanic trainees are declining or unchanged, reports a study in the March issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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The University of Pennsylvania School of Nursing (Penn Nursing) remains the number one nursing school in the world according to a recent ranking by QS World University. The rankings highlight the world’s top universities in 48 different subject areas (as of 2019) based on academic reputation, employer reputation, and research impact. This is the fourth consecutive year that Penn Nursing has taken the top spot.

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When it comes to lifestyle changes that can help people avoid cancer, it turns out the heart has a lot to say on the matter.

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New NCCN Guidelines for Patients: Squamous Cell Skin Cancer explains risk factors and treatment options for cancer type that impacts millions every year.

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A team led by José Bauermeister, PhD, MPH, Presidential Professor of Nursing and Director of the Program on Sexuality, Technology, & Action Research (PSTAR), at the University of Pennsylvania School of Nursing (Penn Nursing) designed the My Desires & Expectations (myDEx) tool to address cognitive and emotional factors that influence YGBMSM sexual decision-making when seeking partners online.

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New preclinical findings from extensive cell and animal studies suggest that cysteamine bitartrate, a drug already used for a rare kidney disease, could benefit patients with some mitochondrial disorders. No proven effective treatments yet exist for these complex conditions with severe energy deficiency

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Most middle-aged and older adults recover their ability to live independently within a year after surgery for hip fracture, reports a study in the Journal of Orthopaedic Trauma. The journal is published in the Lippincott portfolio by Wolters Kluwer.

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A single dose of a PD-1 inhibitor before surgery for melanoma can put patients in remission.

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Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation.

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Both CT angiography and transcranial Doppler have limited accuracy in detecting cerebral vasospasm and predicting delayed cerebral ischemia (DCI) in patients with subarachnoid hemorrhage (SAH) due to ruptured aneurysm, reports a study in the inaugural edition of Critical Care Explorations, the official open-access journal of the Society of Critical Care Medicine (SCCM). The journal is published in the Lippincott portfolio by Wolters Kluwer.

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Efforts to understand costs and openly share information on healthcare prices played a key role in a major Arizona health system's successful turnaround from a financial crisis, according to a feature article in the Spring issue of Frontiers of Health Services Management, an official publication of the American College of Healthcare Executives (ACHE). This journal is published in the Lippincott portfolio by Wolters Kluwer.

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Study in JNCCN finds coronary artery disease costs increase dramatically in patients who are diagnosed with cancer.

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Patients were found to often be willing to share their Google search histories with medical researchers, revealing that many do searches on their health concerns long before deciding to go to the hospital.

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A pair of new studies has provided new insight into the challenges faced by children on the autism spectrum who exhibit symptoms of attention deficit/hyperactivity disorder (ADHD). According to the findings from researchers at Children’s Hospital of Philadelphia (CHOP), these children have difficulty with adaptive behavior, a key measure of independence.

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Cancer clinical trials are an important option for patients with cancer. Yet, once a trial ends, patients still need care plans. Little is known at what point during clinical trial transitions to initiate advance planning discussions or how to educate research teams to communicate with and prepare patient-participants and their families for the next steps after they leave a cancer clinical trial.

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Patients taking diuretics are often at risk for low potassium levels, which can put patients at an increased risk of death from cardiac arrhythmias or other causes. But researchers from the Perelman School of Medicine at the University of Pennsylvania found that taking prescription potassium supplements can reduce these patients’ risk by nearly 10 percent as daily outdoor temperatures increase—a time when patients may be at highest risk due to loss of potassium while sweating. These findings are detailed in a study published today in BMJ Open.

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A new animal study describes how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life. Investigating the fetal signaling pathways active in this biological event may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.

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A new map of newborn babies’ brains offers details of structure that will provide a new reference for researchers studying both typical brain development and neurological disorders. Using noninvasive, 20-minute MRI scans, researchers have revealed some of the complex and precisely organized brain architecture that emerges as the brain reshapes itself during the third trimester of pregnancy.

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Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. Investigating the fetal signaling pathways active in the biological events by which alveoli form may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.

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Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules.

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Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

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A Penn Medicine research team found that the word “told” was tied to almost 20 percent of poor reviews

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Offering compensation can be an important tactic to attract potential participants for enrollment in research studies, but it might come at a cost. A new study conducted by researchers in the Perelman School of Medicine at the University of Pennsylvania found that up to 23 percent of respondents lied about their eligibility to participate in a survey when offered payment, even small amounts.

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Collaborative research by The Wistar Institute and Moffitt Cancer Center has demonstrated that BRAF targeted therapies render resistant melanoma more sensitive to the attack of killer T cells.

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The word “millennial” isn’t exactly a compliment these days. The problem is, all the criticisms out there – “they’re too picky!” or “they’re entitled!” or “they spend all their money on lattes and avocado toast!” – have left it mostly with a negative connotation and rarely a positive one. Any praise for those born between 1981 and 1996 seems to be quickly drowned out by the headlines, memes, and social media posts reinforcing the same old stereotypes of an entire generation. But, in all fairness, millennials are also known to be altruistic, ambitious, and passionate about social injustices, more so than previous generations, many have argued. A USA Today article even described them as the most civic-minded generation in over half a century.

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In his new book, The Class Ceiling: Why it Pays to Be Privileged, Assistant Professor of Sociology Daniel Laurison '99 investigates the ambiguities of meritocracy in white-collar workers’ salaries in the United Kingdom.

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The 2019 Diversity & Inclusion Conference, held March 25-26 in Philadelphia, is an open forum to explore and exchange insights about diversity and inclusion (D&I) best practices for CEOs, diversity officers, educators, corporate leaders and government officials.

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The Wistar Institute announces that it was awarded more than $16M in federal research funds in support of its groundbreaking research in cancer, immunology and infectious diseases.

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A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.

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Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

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Researchers have pinpointed how fibrosis develops in butterfly syndrome patients. The discovery points to a potential treatment for the debilitating complication.

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Companies that improve their "culture of health" realize some important benefits, including reductions in employee health risk factors, medical visits, prescription drug use, and healthcare costs, reports a study in the February Journal of Occupational and Environmental Medicine.

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An international team of collaborators found that the CD4 surface protein, which is used by HIV and SIV as the receptor to enter immune cells, is highly variable among wild chimpanzees.

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Wolters Kluwer, Health announced today that the Journal of Psychosocial Oncology Research & Practice, the newest journal of the International Psycho-Oncology Society (IPOS), will be published under the Lippincott portfolio.

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In this role, Marion Leary, MSN, MPH, RN FAHA, will design and execute innovation programs and projects through Penn Nursing’s Office of Nursing Research (ONR) and will work to keep the School at the forefront of innovation in nursing. The appointment was effective February 1, 2019.

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University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.