Feature Channels: Microbiome

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Released: 13-Jan-2022 4:00 PM EST
Public Health Researchers, Mentors, Educators, and Trainees Honored with 2022 SOT Awards
Society of Toxicology

The 2022 SOT Award recipients represent outstanding individuals in academia, industry, and government whose work in chemical exposures and effects, genetic risk factors, radiation effects, new approach methodologies, the microbiome, and more is improving understanding of health risks.

Released: 10-Jan-2022 6:00 PM EST
Study links gut fungi to intestinal inflammation in Crohn’s disease patients
Case Western Reserve University

Results of a new study by researchers at Case Western Reserve University represent a step toward improving our understanding of Crohn’s disease and the factors that cause its intestinal inflammation.

Newswise: Time, More than Genes, Shapes the Poplar Tree Microbiome
Released: 7-Jan-2022 3:05 PM EST
Time, More than Genes, Shapes the Poplar Tree Microbiome
Department of Energy, Office of Science

Recent work shows that the plant microbiome—the microorganisms in a plant and its immediate environment—influences plant health, survival, and fitness. New research on the microbiome of several types of poplar trees found that the composition of the microbiome changed dramatically over time, and the trees’ genetic makeup proved to be less of a factor than researchers had expected.

Newswise: Science Snapshots from Berkeley Lab
Released: 20-Dec-2021 10:00 AM EST
Science Snapshots from Berkeley Lab
Lawrence Berkeley National Laboratory

A mélange of mini science stories from Berkeley Lab, December 2021.

Released: 15-Dec-2021 2:35 PM EST
Department of Energy Announces $36 Million for Environmental Microbiome Research to Facilitate Predictions of Microbial Interactions and Behavior
Department of Energy, Office of Science

The U.S. Department of Energy (DOE) announced a plan to provide up to $36 million for basic research into microbial processes and community interactions in natural systems.

Released: 3-Dec-2021 4:20 PM EST
COVID-19 infection can be inhibited by elements of the human microbiome
American Society for Microbiology (ASM)

Researchers have identified metabolites, intermediate or end products of metabolism, in the human microbiome that inhibit COVID-19 infection in cell-based models of the virus.

Released: 2-Dec-2021 2:15 PM EST
Immune cells in the brain play key role in relationship between gut microbes and beta-amyloid
University of Chicago Medical Center

Perturbing the gut microbiome with antibiotics during early life leads to a reduction in amyloid plaques in male mice in adulthood — and microglia are a critical component of the effect.

Released: 2-Dec-2021 10:15 AM EST
Are pandemic-related stressors increasing young women’s vulnerability to STIs?
University of Illinois Chicago

Researchers will study how pandemic-related stressors influence sexual behavior and risk of sexually transmitted infections among girls and young women in Kenya, where a dramatic increase in infections has been revealed in preliminary data, compared to 12-18 months prior.

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Released: 1-Dec-2021 3:10 PM EST
A Newly Discovered Enzyme Makes Ethylene and Methane
Department of Energy, Office of Science

Scientists know that ethylene comes from microbes, but the only known natural microbial processes that produce ethylene require oxygen. But now a team of scientists have discovered an enzyme system from bacteria called methylthio-alkane reductases that work without oxygen, instead scavenging sulfur to produce ethylene, ethane, or methane as a byproduct. The research may have applications in biofuels.

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Released: 29-Nov-2021 10:35 AM EST
Catching all the action from twitch to hatch
National Institute of Biomedical Imaging and Bioengineering

A team led by NIBIB scientists has developed hardware and software innovations to construct super-resolution, 3D confocal images of fine structures in living samples.

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Released: 22-Nov-2021 6:30 PM EST
Is the relationship between diet, intestinal bacteria and cells key to preventing systemic inflammation?
University of California, Los Angeles (UCLA), Health Sciences

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

Released: 22-Nov-2021 1:50 PM EST
COVID-19 Testing Kits Also Can Measure Oral Microbiome in Saliva
Rutgers University-New Brunswick

COVID-19 saliva testing kits that include a novel preservative can also be used measure microscopic organisms in the mouth, a Rutgers study found. This enables study of the relationship between mouth and lung microbes and the SARS-CoV-2 virus that may allow for the development of new treatments.

Newswise: Decoding biological mysteries with algae: NAU team wins $3M from NSF to model microbiome
Released: 18-Nov-2021 10:05 AM EST
Decoding biological mysteries with algae: NAU team wins $3M from NSF to model microbiome
Northern Arizona University

The tiny cosmos of organisms living on a streamer of algae in a river could help scientists learn what turns an environment from healthy to toxic and back again. A multidisciplinary team led by NAU has won $3 million from the NSF to translate the codex contained in the microbiome of common algae into computer algorithms that can predict a wide range of microbial interactions.

Released: 17-Nov-2021 6:10 PM EST
Exercise increases the body’s own ‘cannabis’ which reduces chronic inflammation, says new study
University of Nottingham

Exercise increases the body’s own cannabis-like substances, which in turn helps reduce inflammation and could potentially help treat certain conditions such as arthritis, cancer and heart disease.

Newswise: Fraternizing vampire bats share 'social microbiomes'
Released: 16-Nov-2021 6:15 PM EST
Fraternizing vampire bats share 'social microbiomes'
University of Illinois at Urbana-Champaign

In an unusual study, researchers brought vampire bats from distant Panamanian populations together for four months in a laboratory setting and tracked how the bats’ gut microbes changed over time.

Newswise: Diet, Gut Microbes and Immunity
Released: 16-Nov-2021 5:35 PM EST
Diet, Gut Microbes and Immunity
Harvard Medical School

Research in mice demonstrates how diet alters a gut microbe molecule that, in turn, prompts immune cells to downregulate inflammation.

Newswise: Technology that Measures Cell-by-Cell Variation in Growth Rates Could Impact Many Fields
Released: 12-Nov-2021 2:50 PM EST
Technology that Measures Cell-by-Cell Variation in Growth Rates Could Impact Many Fields
Stony Brook University

Few techniques exist to measure cell-by-cell metabolic variations, a powerful way to understand cell responses. Researchers from Stony Brook University demonstrated in a published study that Raman microspectroscopy can accurately measure cell-by-cell variations in growth rates of the bacterium E. coli.

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Released: 12-Nov-2021 12:25 PM EST
Building bacteria to keep us well
Washington University in St. Louis

Close-up of E. coli bacteria. Tae Seok Moon, professor in the McKelvey School of Engineering, has designed a biosensor, using E. coli as a starting point from which to build a system that can detect individual chemicals in a person's gut.

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Released: 9-Nov-2021 5:05 PM EST
Probing How Microbiomes Affect Our Health
Pacific Northwest National Laboratory

Customized molecular tools identify specific microbial functions that are key to healthy people and environments.

Newswise: McMaster scientists pinpoint key trigger of Crohn’s disease
1-Nov-2021 1:35 PM EDT
McMaster scientists pinpoint key trigger of Crohn’s disease
McMaster University

Researchers gleaned their results by analyzing blood and biopsy samples from two groups totalling 18 people with Crohn’s disease, comparing them to a matching number of people from two healthy control groups. A mouse model of IBD was also used. Khan said his study was the first demonstration of the interaction between serotonin, autophagy and gut microbiota in intestinal inflammation. The paper was published by Science Advances today. Sabah Haq, a PhD student who works with Khan, is first author.

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Released: 3-Nov-2021 4:35 PM EDT
Predatory Bacteria, Eat Thy Neighbor
Department of Energy, Office of Science

Ecologists know that adding more plant food that prey animals eat can also benefit predators. Scientists wanted to know if the same principles apply in bacterial food webs. They found that predatory bacteria grow faster and consume more resources than non-predators, and they use predatory behavior and physical features to hunt and feast on prey bacteria.

27-Oct-2021 11:45 AM EDT
Cleveland Clinic Study Links Gut Microbiome and Aggressive Prostate Cancer
Cleveland Clinic

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

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Released: 19-Oct-2021 4:15 PM EDT
Bacteria, fungi interact far more often than previously thought
Los Alamos National Laboratory

In a novel, broad assessment of bacterial-fungal interactions, researchers using unique bioinformatics found that fungi host a remarkable diversity of bacteria, making bacterial-fungal interactions far more common and diverse than previously known.

Newswise: Cat Bacteria Treats Mouse Skin Infection, May Help You and Your Pets As Well
Released: 19-Oct-2021 11:35 AM EDT
Cat Bacteria Treats Mouse Skin Infection, May Help You and Your Pets As Well
University of California San Diego Health

Researchers at UC San Diego School of Medicine identify a strain of bacteria on healthy cats that produces antibiotics against severe skin infections. The findings may soon lead to new bacteriotherapies for humans and their pets, wherein cat bacteria is applied via topical cream or spray.

Released: 12-Oct-2021 12:00 PM EDT
Latest Research on Influence of Sex, Gender on Health and Disease to Be Presented at APS Conference
American Physiological Society (APS)

Scientists specializing in research on sex and gender differences in diseases of the cardiovascular, renal, endocrine and immune systems will meet virtually October 19–22, 2021, for the American Physiological Society’s (APS) New Trends in Sex and Gender Medicine conference.

Released: 1-Oct-2021 3:45 PM EDT
War in the gut: How human microbiota resist the cholera bacterium
École Polytechnique Fédérale de Lausanne (EPFL)

Cholera is still an enormous problem. An acute diarrheal disease, there have been seven major pandemics in the last two hundred years.

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Released: 1-Oct-2021 1:25 PM EDT
Age and Aging Have Critical Effects on the Gut Microbiome

Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The findings have been published in the journal Cell Reports.

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Released: 28-Sep-2021 5:05 PM EDT
How high-fat diets allow cancer cells to go unnoticed
Cold Spring Harbor Laboratory

A high-fat diet increases the incidence of colorectal cancer. Cold Spring Harbor Laboratory Fellow Semir Beyaz and collaborators from Harvard Medical School and Massachusetts Institute of Technology have discovered that in mice, fat disrupts the relationship between intestinal cells and the immune cells that patrol them looking for emerging tumors.

Released: 28-Sep-2021 4:00 PM EDT
Mayo Clinic

这项发表在《基因组医学》(Genome Medicine)上的研究发现,通过关注胃肠道中数万亿的细菌、病毒和真菌,即肠道微生物组,可以预测类风湿性关节炎患者的未来预后。研究结果表明,肠道微生物与类风湿性关节炎患者的预后有关。

Released: 28-Sep-2021 4:00 PM EDT
باحثو مايو يربطون بين الحَيُّوم الدقيق للأمعاء ومآل مرض التهاب المفاصل الروماتويدي
Mayo Clinic

لقد وجدت الدراسة، المنشورة في مجلة طب الجينوم، أن التنبؤ بمآل مرض التهاب المفاصل الروماتويدي للمريض قد يكون ممكنًا من خلال التركيز على تريليونات البكتيريا والفيروسات والفطريات التي تعيش في السبيل المَعدي المَعوي، والمعروفة باسم الحَيُّوم الدقيق للأمعاء

Released: 28-Sep-2021 1:50 PM EDT
Pesquisadores da Mayo associam o microbioma intestinal ao prognóstico de artrite reumatoide
Mayo Clinic

O estudo, publicado na Genome Medicine, descobriu que a previsão do futuro prognóstico de artrite reumatoide de um paciente poderia ser possível ao direcionar o foco para os trilhões de bactérias, vírus e fungos que habitam o trato gastrointestinal, conhecido como microbioma intestinal.

Released: 28-Sep-2021 1:45 PM EDT
Investigadores de Mayo vinculan microbioma intestinal con pronóstico de artritis reumatoide
Mayo Clinic

El estudio se publicó en Genome Medicine y descubrió que posiblemente se puede predecir el futuro de la artritis reumatoide de un paciente al dirigir la atención hacia los billones de bacterias, virus y hongos que habitan en el tracto gastrointestinal, conocidos como microbioma intestinal.

Released: 28-Sep-2021 7:00 AM EDT
Endothelin Experts to Gather for Virtual APS Conference
American Physiological Society (APS)

Endothelin (ET) researchers from across the globe will meet virtually October 4–7, 2021, at the Seventeenth International Conference on Endothelin (ET-17), hosted and organized by the American Physiological Society (APS).

17-Sep-2021 2:00 PM EDT
Children’s dislike of cauliflower, broccoli could be written in their microbiome
American Chemical Society (ACS)

Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have found that levels of volatile, sulfurous compounds are similar in parent-child pairs, suggesting shared oral microbiomes. They also found that high levels cause children to dislike the vegetables.

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16-Sep-2021 7:00 PM EDT
Gut bacteria might be an indicator of colon cancer risk
University of Washington School of Medicine and UW Medicine

Researchers are finding a link between the increased presence of certain bacteria in a gut biome and colon cancer.

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Released: 17-Sep-2021 8:30 AM EDT
Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
Lawrence Berkeley National Laboratory

A study recently published in Nature Communications suggests that displacing cold-water communities of algae with warm-adapted ones threatens to destabilize the delicate marine food web. The team was led by University of East Anglia researchers and included DOE Joint Genome Institute researchers.

Released: 15-Sep-2021 5:05 PM EDT
Gut microbiota influences the ability to lose weight
American Society for Microbiology (ASM)

Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.

Released: 14-Sep-2021 3:40 PM EDT
Probiotic-Containing Yogurt Protects Against Microbiome Changes That Lead to Antibiotic-Induced Diarrhea, Study Finds
University of Maryland School of Medicine

Eating yogurt containing a particular strain of a well-studied probiotic appears to protect against harmful changes in the gut microbiome that are associated with antibiotic administration.

Released: 14-Sep-2021 12:15 PM EDT
Mayo researchers link gut microbiome to rheumatoid arthritis prognosis
Mayo Clinic

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic's Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient's future rheumatoid arthritis prognosis could be possible by zeroing in on the trillions of bacteria, viruses and fungi that inhabit their gastrointestinal tract, known as the gut microbiome. The findings suggest that gut microbes and a patient's outcome of rheumatoid arthritis are connected.

Released: 13-Sep-2021 9:00 AM EDT
MD Anderson and SNIPR BIOME collaborate to advance next-generation CRISPR microbiome therapeutics
University of Texas M. D. Anderson Cancer Center

MD Anderson and SNIPR BIOME have announced a strategic collaboration to advance next-generation CRISPR-based microbiome therapies to reduce immune-related side effects in patients treated with immune checkpoint inhibitors.

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Released: 8-Sep-2021 4:25 PM EDT
Making the microbiome more amenable to cancer immunotherapy
National Institute of Biomedical Imaging and Bioengineering

The gut microbiome can impact us in a variety of different ways, from our metabolism to our mood. Now, NIBIB-funded researchers are investigating if a fiber-based gel can restore beneficial microbes in the gut to enhance the efficacy of immune checkpoint inhibitors, a type of cancer immunotherapy treatment, in mice.

Released: 7-Sep-2021 2:30 PM EDT
Bacteria could learn to predict the future
Washington University in St. Louis

Using computer simulations and a simple theoretical model, a new paper shows how bacteria could adapt to a fluctuating environment by learning its statistical regularities — for example, which nutrients tend to be correlated — and do so faster than evolutionary trial-and-error would normally allow.

Newswise: Gut Bacteria Influence Brain Development
3-Sep-2021 5:05 AM EDT
Gut Bacteria Influence Brain Development
University of Vienna

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role. The research team found that the overgrowth of the gastrointestinal tract with the bacterium Klebsiella is associated with an increased presence of certain immune cells and the development of neurological damage in premature babies. The study is now published in journal Cell Host & Microbe.

Released: 2-Sep-2021 2:25 PM EDT
Mayo Clinic

妙佑医疗国际(Mayo Clinic) 和Wellesley学院的研究人员在《内分泌学与代谢学动态》(Trends in Endocrinology & Metabolism)上发表的一篇评论文章中着重讨论了类固醇对肠道和阴道微生物组的相互作用如何影响女性的健康结果。

Released: 2-Sep-2021 2:10 PM EDT
الباحثون يراجعون كيفية تغيير الستيرويدات الجنسية الحَيُّوم الدقيق المهبلي والمعوي
Mayo Clinic

ركز باحثو مايو كلينك وكلية ويلزلي على كيفية تأثير تفاعلات الستيرويدات في الحيّومات الدقيقة المهبلية والمعوية على النتائج الصحية للمرأة في مراجعة نُشرت في مجلة اتجاهات في علم الغدد الصماء والأيض.

Released: 2-Sep-2021 1:25 PM EDT
Pesquisadores analisam como os esteroides sexuais alteram o microbioma intestinal e vaginal
Mayo Clinic

Pesquisadores da Mayo Clinic e do Wellesley College se concentraram em como as interações dos esteroides nos microbiomas intestinais e vaginais influenciam a saúde da mulher em uma análise publicada na revista médica Trends in Endocrinology & Metabolism.

Released: 2-Sep-2021 1:20 PM EDT
Investigadores analizan cómo las hormonas sexuales esteroideas cambian la microbiota intestinal y vaginal
Mayo Clinic

En una revisión publicada en Tendencias en Endocrinología y Metabolismo, los investigadores de Mayo Clinic y de Wellesley College se concentraron en cómo influye sobre la salud femenina la interacción entre hormonas esteroideas, microbiota vaginal y microbiota intestinal.

30-Aug-2021 7:00 AM EDT
High Virus Count in the Lungs Drives COVID-19 Deaths
NYU Langone Health

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds. The results contrast with previous suspicions that simultaneous infections, such as bacterial pneumonia or overreaction of the body’s immune defense system, played major roles in heightened risk of death, the investigators say.

Released: 30-Aug-2021 4:20 PM EDT
Closing the gate on manganese could open doors to new drugs to treat pneumonia
SLAC National Accelerator Laboratory

Drawing on SLAC facilities, Australian researchers have revealed how Streptococcus pneumoniae bacteria obtain manganese from our bodies, which could lead to better therapies to target the pathogen.

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