Curated News: National Heart, Lung, and Blood Institute (NHLBI)

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Released: 7-Aug-2023 12:40 PM EDT
Research Explores Patient Experience of North Carolina's Medicaid Transition
Atrium Health Wake Forest Baptist

In 2021, 1.6 million Medicaid beneficiaries in North Carolina moved from a fee-for-service Medicaid model to a managed care system known as N.C. Medicaid Managed Care. What impact did the transition have on Medicaid enrollees who live in Forsyth County?

Released: 31-Jul-2023 8:30 AM EDT
Icahn School of Medicine at Mount Sinai Receives $11.5 Million Grant Renewal to Study the Impact of Psychosocial Stress on Cardiovascular Disease
Mount Sinai Health System

Psychosocial stress profoundly affects people’s lives globally, not least because it can be a critical risk factor for cardiovascular disease. Thanks to an $11.5 million award renewal from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, distinguished researchers at the Icahn School of Medicine at Mount Sinai and elsewhere aim to gain a deeper understanding of how stress influences cardiovascular health.

Released: 27-Jul-2023 10:45 AM EDT
Storing fat at the waist may NOT up diabetes risk, surprise findings indicate
University of Virginia Health System

Conventional wisdom holds that storing fat around your belly puts you at increased risk for type 2 diabetes. But surprising new findings from the University of Virginia School of Medicine suggest that naturally occurring variations in our genes can lead some people to store fat at the waist but also protect them from diabetes.

Released: 20-Jul-2023 4:05 PM EDT
Omega-3 fatty acids appear promising for maintaining lung health
NIH, National Heart, Lung and Blood Institute (NHLBI)

Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults supported by the National Institutes of Health.

Released: 18-Jul-2023 11:45 AM EDT
A key function for tight junctions in embryo models
Gladstone Institutes

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these signaling molecules guide a single layer of embryonic stem cells to form three layers of distinct cell types that will later become different parts of the body.

   
Released: 12-Jul-2023 12:35 PM EDT
Blood pressure patterns in the first half of pregnancy improve early prediction of preeclampsia and gestational hypertension
Kaiser Permanente

Routine blood pressure readings recorded in the first half of pregnancy can be divided into 6 distinct patterns that can effectively stratify patients by their risk of developing preeclampsia and gestational hypertension later in pregnancy, Kaiser Permanente researchers found.

Released: 7-Jul-2023 11:20 AM EDT
Researchers uncover how a genetic mutation can cause individuals with normal cholesterol levels to develop coronary artery disease at a young age
University of Texas Health Science Center at Houston

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s – with normal cholesterol levels and no other risk factors — to develop coronary artery disease has been identified, according to researchers with UTHealth Houston.

Newswise: Produce Prescription Programs for Patients with Diabetes Could Save Billions in Healthcare Costs, Study Shows
Released: 7-Jul-2023 8:20 AM EDT
Produce Prescription Programs for Patients with Diabetes Could Save Billions in Healthcare Costs, Study Shows
Tufts University

A modeled implementation of a nationwide produce prescription program—which would provide free or discounted fruits and vegetables to eligible Americans living with diabetes —projected extensive reductions in national rates of cardiovascular disease and associated healthcare costs.

30-Jun-2023 2:05 PM EDT
Fluctuating Levels of Cholesterol and Triglycerides Linked to Increased Risk of Dementia
American Academy of Neurology (AAN)

Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer’s disease and related dementias compared to people who have steady levels, according to new research published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia.

Newswise: Study Sets New Standard for Graft-Versus-Host Disease Prevention After Stem Cell Transplant
Released: 22-Jun-2023 1:15 PM EDT
Study Sets New Standard for Graft-Versus-Host Disease Prevention After Stem Cell Transplant
Johns Hopkins Medicine

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published in the New England Journal of Medicine. The new standard is more effective at preventing GVHD and came with less side effects, compared with the current gold standard.

Released: 8-Jun-2023 9:30 AM EDT
Discovering Cell Identity: $6 Million NIH Grant Funds New Penn Medicine Research to Uncover Cardiac Cell Development
Perelman School of Medicine at the University of Pennsylvania

Historically, scientists have studied how cells develop and give rise to specialized cells, such as heart, liver, or skin cells, by examining specific proteins.

Newswise: Mount Sinai Researchers Use New Deep Learning Approach to Enable Analysis of Electrocardiograms as Language
2-Jun-2023 12:35 PM EDT
Mount Sinai Researchers Use New Deep Learning Approach to Enable Analysis of Electrocardiograms as Language
Mount Sinai Health System

Mount Sinai researchers have developed an innovative artificial intelligence (AI) model for electrocardiogram (ECG) analysis that allows for the interpretation of ECGs as language. This approach can enhance the accuracy and effectiveness of ECG-related diagnoses, especially for cardiac conditions where limited data is available on which to train. In a study published in the June 6 online issue of npj Digital Medicine DOI: 10.1038/s41746-023-00840-9, the team reported that its new deep learning model, known as HeartBEiT, forms a foundation upon which specialized diagnostic models can be created. The team noted that in comparison tests, models created using HeartBEiT surpassed established methods for ECG analysis.

24-May-2023 11:35 AM EDT
Afternoon Exercise Linked with Greater Improvements in Blood Sugar Levels for Patients with Type 2 Diabetes
Brigham and Women’s Hospital

Over 37 million Americans have diabetes, and 90-95% of that population are diagnosed with type 2 diabetes. Lifestyle interventions, such as a healthy diet and a regular physical activity program, are methods to manage diabetes.

18-May-2023 6:05 PM EDT
A commonly used tool is suboptimal in predicting osteoporosis fracture risk in younger post-menopausal women
University of California, Los Angeles (UCLA), Health Sciences

The commonly used U.S version of the Fracture Risk Assessment Tool (FRAX) should not be routinely used to select younger postmenopausal women for bone mineral density testing. But the Osteoporosis Self-Assessment Tool (OST) is excellent at identifying women with osteoporosis-level bone mineral density, which is the goal of these screenings, while FRAX is not.

Released: 27-Apr-2023 6:25 PM EDT
COVID-19 linked to financial toll on patients
Michigan Medicine - University of Michigan

The lingering effects of COVID-19 on some patients’ health has gotten a lot of attention. But a new study suggests many face long-term major financial impacts after their illness. Whether or not they got hospitalized during their bout with COVID-19, patients had a higher risk of serious money problems after their infection, compared with a comparison group of individuals whose financial outcomes were measured prior to getting COVID-19.

Released: 27-Apr-2023 2:00 PM EDT
How Cross-Sector Coalitions Can Improve Public Health
Tufts University

A new study by researchers at the Friedman School of Nutrition Science and Policy at Tufts University and others, shows how bringing together coalitions of individuals from government, public health, healthcare, public education, and other arenas to address a public health issue--in this case early childhood obesity--can result in better policies, systems, and environments for change.

Released: 18-Apr-2023 8:00 AM EDT
Keys to women’s resilience after 80: more education, less stress
Ohio State University

Having a four-year college degree and a low level of stress are strongly linked to psychological resilience in American women aged 80 and older, a new study suggests.

   
Released: 13-Apr-2023 9:40 AM EDT
FSU researchers examine role of crucial hormone and exercise with $1.8 million NIH grant
Florida State University

A new, $1.8 million Florida State University study funded by the National Institutes of Health will examine the role adiponectin plays in the circulatory system of aging adults and how exercise affects its influence on vascular health. The research aims to offer more insight into how exercise brings benefits and explore how adiponectin can potentially be used for treatment.

Newswise: VUMC-Led Trial Shows Two Investigational Drugs Are Ineffective for Treating Severe COVID-19
Released: 11-Apr-2023 12:00 PM EDT
VUMC-Led Trial Shows Two Investigational Drugs Are Ineffective for Treating Severe COVID-19
Vanderbilt University Medical Center

A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.

3-Apr-2023 3:30 PM EDT
CHOP-led Study Identifies Two Different Regulatory T Cell Populations
Children's Hospital of Philadelphia

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children’s Hospital of Philadelphia (CHOP). The findings, published today in Science Immunology, could pave the way for new treatments for autoimmune diseases that target the immune system selectively.

Released: 6-Apr-2023 2:30 PM EDT
Disparities identified among patients receiving advanced pulmonary support
NIH, National Heart, Lung and Blood Institute (NHLBI)

Some adults with severe respiratory illness, including women, those with public insurance, and people with fewer financial resources, may be less likely to receive an advanced form of life support known as extracorporeal membrane oxygenation (ECMO).

Released: 3-Apr-2023 3:55 PM EDT
Small proteins in heart play big role
Washington University in St. Louis

A heartbeat is a carefully coordinated series of electrical signals led by sodium ion channels, which tell the heart when to contract and to relax. Any disruption to these signals may lead to cardiac diseases such as an irregular heartbeat, or arrhythmia. Two researchers at Washington University in St. Louis have taken a closer look at this process at the molecular level and have found what may provide new insights into different heart conditions and how to develop better therapies.

Released: 23-Mar-2023 10:20 AM EDT
BIDMC Research Guides FDA Action on Common Medical Device
Beth Israel Deaconess Medical Center

In a retrospective cohort study of Medicare beneficiaries who underwent aortic stent grafting, researchers worked with the Food and Drug Administration (FDA) to compare the long-term outcomes of a specific endograft device type with comparative devices on the market.

Released: 13-Mar-2023 2:30 PM EDT
Wayne State researchers develop new technology to easily detect active TB
Wayne State University Division of Research

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

Newswise: With $13M, UIC scientists will study lung inflammation mechanisms
Released: 6-Mar-2023 5:05 PM EST
With $13M, UIC scientists will study lung inflammation mechanisms
University of Illinois Chicago

The research team consists of six investigators who will lead three separate project grants and three separate cores, in the hopes of finding new avenues for research and treatments to help patients who suffer from conditions like chronic obstructive pulmonary disorder, pulmonary fibrosis and acute respiratory distress disorder, a common and serious complication of COVID-19.

Newswise: Possible treatment strategy identified for bone marrow failure syndrome
28-Feb-2023 5:40 PM EST
Possible treatment strategy identified for bone marrow failure syndrome
Washington University in St. Louis

Research led by Washington University School of Medicine in St. Louis has identified a possible treatment strategy for a rare bone marrow failure syndrome that is named poikiloderma with neutropenia. The work also may have implications for treating other bone marrow failure syndromes with similar underlying dysfunctions.

Newswise: Study Finds Association Between Lifetime Experiences of Discrimination and Incidence of Dementia
Released: 28-Feb-2023 10:05 AM EST
Study Finds Association Between Lifetime Experiences of Discrimination and Incidence of Dementia
Wake Forest University School of Medicine

According to new research from Wake Forest University School of Medicine, people who experience discrimination during their lifetimes have an increased risk of dementia. The study appears in the February issue of Alzheimer’s & Dementia, the journal of the Alzheimer’s Association.

Released: 24-Feb-2023 5:10 PM EST
Rutgers Researchers to Study the Impact of Multiple Health Conditions on Medication Outcomes in Older Adults
Rutgers University-New Brunswick

The National Institutes of Health has awarded Rutgers a $3.5 million grant to conduct a five-year study exploring the impact medications have on older adults with multiple medical conditions.

Newswise: Custom, 3D-printed heart replicas look and pump just like the real thing
Released: 22-Feb-2023 6:05 PM EST
Custom, 3D-printed heart replicas look and pump just like the real thing
Massachusetts Institute of Technology (MIT)

No two hearts beat alike. The size and shape of the the heart can vary from one person to the next. These differences can be particularly pronounced for people living with heart disease, as their hearts and major vessels work harder to overcome any compromised function.

   

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This news release is embargoed until 13-Feb-2023 5:00 PM EST Released to reporters: 9-Feb-2023 2:40 PM EST

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Newswise: New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Released: 2-Feb-2023 1:10 PM EST
New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it. Their analysis, using a large national administrative database with records for pregnant people with SCD, found the maternal mortality rate was 26 times greater than the national average. This figure has not improved since the last time this population was assessed.

Released: 2-Feb-2023 11:05 AM EST
NIH-Funded Research to Develop Pneumonia Severity Prediction Tool to Improve Emergency Care of Children
Ann and Robert H. Lurie Children's Hospital of Chicago

Todd Florin, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago recently was awarded a $5.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) for a multicenter study to derive and broadly validate the first emergency department (ED)-based pediatric community-acquired pneumonia severity (PedCAPS) score. This objective score will help avoid many unnecessary hospitalizations in children at low risk of severe outcomes, while targeting more focused therapies towards the lower proportion of children at highest risk for severe disease.

20-Jan-2023 1:25 PM EST
Early Cardiovascular Disease Linked to Worse Brain Health in Middle Age
American Academy of Neurology (AAN)

People with early cardiovascular disease may be more likely to have memory and thinking problems and worse brain health in middle age, according to new research published in the January 25, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Newswise: More Steps, Moderate Physical Activity Cuts Dementia, Cognitive Impairment Risk
24-Jan-2023 6:35 PM EST
More Steps, Moderate Physical Activity Cuts Dementia, Cognitive Impairment Risk
University of California San Diego

UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.

Released: 23-Jan-2023 1:05 PM EST
Head Injury is Associated with Doubled Mortality Rate Long-Term, Penn Study Finds
Perelman School of Medicine at the University of Pennsylvania

A new study reveals adults who suffered any head injury during a 30-year study period had two times the rate of mortality than those who did not have any head injury, and mortality rates among those with moderate or severe head injuries were nearly three times higher.

Released: 18-Jan-2023 5:55 PM EST
Delayed appendicitis diagnosis more common among non-Hispanic Black adults
Northwestern University

Non-Hispanic Black adults more frequently experience delays in receiving an appendicitis diagnosis in hospital emergency departments, putting them at a higher likelihood of perforated appendicitis and subsequent post-surgical infections, reports a new Northwestern Medicine study.

Newswise: Study reveals obesity-related trigger that can lead to diabetes
10-Jan-2023 2:00 PM EST
Study reveals obesity-related trigger that can lead to diabetes
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that a defect in an enzyme called APT1 interferes with the ability to secrete insulin, contributing to the development of Type 2 diabetes in people who are overweight or obese.

Newswise: Digital Marker for Coronary Artery Disease Built by Researchers at Mount Sinai
19-Dec-2022 7:00 PM EST
Digital Marker for Coronary Artery Disease Built by Researchers at Mount Sinai
Mount Sinai Health System

Using machine learning and clinical data from electronic health records, researchers at the Icahn School of Medicine at Mount Sinai in New York constructed an in silico, or computer-derived, marker for coronary artery disease (CAD) to better measure clinically important characterizations of the disease.

Newswise: Household Air Cleaners Improve Heart Health Among Individuals with COPD, Researchers Find
Released: 5-Dec-2022 10:00 AM EST
Household Air Cleaners Improve Heart Health Among Individuals with COPD, Researchers Find
Johns Hopkins Medicine

A six-month study led by Johns Hopkins Medicine researchers concludes that the use of portable home air purifiers can improve some markers of cardiovascular health in people with chronic obstructive pulmonary disease, or COPD

Newswise: HIV Infection Leaves a ‘Memory’ in Cells
Released: 22-Nov-2022 11:25 AM EST
HIV Infection Leaves a ‘Memory’ in Cells
George Washington University

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, impacting the longevity and quality of their lives.

Newswise: Tufts University Researchers Find Link Between Foods Scored Higher By New Nutrient Profiling System and Better Long-Term Health Outcomes
18-Nov-2022 8:10 AM EST
Tufts University Researchers Find Link Between Foods Scored Higher By New Nutrient Profiling System and Better Long-Term Health Outcomes
Tufts University

Tufts researchers show that a holistic food profiling system, Food Compass, identifies better overall health and lower risk for mortality. The team assessed whether adults who ate more foods with higher Food Compass scores had better long-term health outcomes and found that they did.

   
Released: 18-Nov-2022 11:05 AM EST
Rutgers Scientists Produce “DNA Virus Vaccine” to Fight DNA Viruses
Rutgers University-New Brunswick

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

Newswise: Estudio: Durante la Pandemia, Disminuyó el Control de la Presión Arterial
Released: 9-Nov-2022 12:55 PM EST
Estudio: Durante la Pandemia, Disminuyó el Control de la Presión Arterial
Cedars-Sinai

De acuerdo a un nuevo análisis dirigido por investigadores de Cedars-Sinai y llevado a cabo en tres grandes sistemas de salud, el control y manejo de la hipertensión empeoraron durante los primeros meses de la pandemia de COVID-19.

Released: 7-Nov-2022 6:05 PM EST
Restored blood flow meant less pain, better quality of life for those with leg artery disease
American Heart Association (AHA)

estoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

Released: 1-Nov-2022 7:35 PM EDT
Study Shows Blood Pressure Levels Rose During Pandemic
NIH, National Heart, Lung and Blood Institute (NHLBI)

Adults with hypertension saw a small, but consequential, rise in their blood pressure levels during the first eight months of the COVID-19 pandemic, while the number of times they had their blood pressure measured dropped significantly, according to a study supported by the National Institutes of Health.

Newswise: Study: First-Degree Relatives of Patients with NAFLD at Risk of Liver Disease
Released: 1-Nov-2022 3:15 PM EDT
Study: First-Degree Relatives of Patients with NAFLD at Risk of Liver Disease
UC San Diego Health

New study identifies that first-degree relatives of patients with nonalcoholic fatty liver disease with advanced fibrosis (scarring of the liver) are at a 15% risk of developing the condition.

Newswise: Study: During Pandemic, High Blood Pressure Control Declined
Released: 1-Nov-2022 1:25 PM EDT
Study: During Pandemic, High Blood Pressure Control Declined
Cedars-Sinai

Hypertension control and management worsened during the early months of the COVID-19 pandemic, according to a new analysis conducted at three large health systems, led by Cedars-Sinai investigators.

Newswise: Study Identifies Potential New Treatment Target for Sleep Apnea
Released: 31-Oct-2022 10:00 AM EDT
Study Identifies Potential New Treatment Target for Sleep Apnea
Johns Hopkins Medicine

In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people.

Newswise: AI Improves Accuracy of Heart Condition Diagnosis
Released: 27-Oct-2022 6:10 PM EDT
AI Improves Accuracy of Heart Condition Diagnosis
Cedars-Sinai

Several recent discoveries show that the accuracy of diagnosing coronary artery disease and predicting patient risk is improved with the help of artificial intelligence (AI) models developed by scientists in the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

21-Oct-2022 6:15 PM EDT
Telehealth Follow-Up Associated with Increased Returns and Hospitalizations After Emergency Department Visit
University of California, Los Angeles (UCLA), Health Sciences

Telehealth follow-up consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients compared with in-person follow-ups,


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