Curated News: National Institute of Dental and Craniofacial Research (NIDCR)

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Released: 16-Apr-2020 9:30 AM EDT
NYU Dentistry Awarded $2.2 Million NIH Grant to Investigate How Oral Cancer Causes Pain
New York University

The National Institute of Dental and Craniofacial Research has awarded NYU College of Dentistry’s Yi Ye, PhD, a $2.2 million, five-year grant to study the role of Schwann cells, the most prevalent type of cell supporting neurons in the peripheral nervous system, in oral cancer progression and pain.

Newswise: Mimicking Cancer’s Evasive Tactics, Microparticles Show Promise Against Transplant Rejection
8-Mar-2020 9:00 PM EDT
Mimicking Cancer’s Evasive Tactics, Microparticles Show Promise Against Transplant Rejection
Health Sciences at the University of Pittsburgh

Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own, while leaving the immune system intact.

19-Feb-2020 1:10 PM EST
Vaping Changes Oral Microbiome, Increasing Risk for Infection
New York University

Using e-cigarettes alters the mouth’s microbiome—the community of bacteria and other microorganisms—and makes users more prone to inflammation and infection, finds a new study led by researchers at NYU College of Dentistry.

Newswise:Video Embedded study-reveals-how-too-much-fluoride-causes-defects-in-tooth-enamel
VIDEO
18-Feb-2020 8:00 AM EST
Study Reveals How Too Much Fluoride Causes Defects in Tooth Enamel
New York University

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel—a novel explanation for how dental fluorosis, a condition caused by overexposure to fluoride during childhood, arises. The study, led by researchers at NYU College of Dentistry, is published in Science Signaling.

11-Feb-2020 2:15 PM EST
Absent p53, oral cancers recruit and reprogram nerves to fuel tumor growth
University of Texas M. D. Anderson Cancer Center

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progress.

Newswise: Mouse Study Shows Nerve Signaling Pathway Critical to Healing Fractures
Released: 5-Dec-2019 11:00 AM EST
Mouse Study Shows Nerve Signaling Pathway Critical to Healing Fractures
Johns Hopkins Medicine

Sticks and stones may break one’s bones, but healing them requires the production of a protein signal that stimulates the generation, growth and spread of vital nerve cells, or neurons, throughout the injured area. That’s the finding of a recent Johns Hopkins Medicine study that used mice to demonstrate what likely takes place during human fracture repair as well.


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