A $3 million, five-year award from the National Institute of Environmental Health Sciences of the NIH aims to discover and validate the gene Х heavy metal (GXM) interactions in human livers and to understand their role in nonalcoholic fatty liver disease
Nanozymes—artificial enzymes that can carry out pre-determined chemical reactions—could selectively activate a cancer drug within a tumor while minimizing damage to healthy tissue in a mouse model of triple negative breast cancer.
New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes’ on/off switches.
Rutgers is part of a national network of institutions tasked with ensuring workers have the knowledge and skills to stay safe on the job.
Women diagnosed and treated for breast cancer have increased biological aging compared to women who remain free of breast cancer, according to a new study by researchers at the National Institutes of Health and their collaborators. Among women diagnosed with breast cancer, the association with faster biological aging was most pronounced for those who received radiation therapy, while surgery showed no association with biological aging. This finding suggests that developing cancer is not what increases the aging effect.
Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.
New five-year award will focus on the effects of environmental exposures on health across the lifespan
The Program in Public Health at the University of California, Irvine has received a five-year, $2.7 million grant from the National Institute of Environmental Health Sciences to research the connection between low-level lead exposure during pregnancy and early childhood and children’s school performance and behavior in Santa Ana, California.
The risks of exposure to “forever chemicals” start even before birth, a new study confirms, potentially setting up children for future health issues.
Researchers at the Beckman Institute for Advanced Science and Technology found that early exposure to an environmental chemical called polychlorinated biphenyls, or PCBs, made it more difficult for mice to recover from sound-related trauma sustained later in life.
Air pollution has been shown to have a negative effect on the prognosis of ischemic stroke, or stroke caused by reduced blood flow to the brain, but the exact mechanism is unknown. A team of researchers recently conducted a study to determine whether or not increased inflammation of the brain, also known as neuroinflammation, is the main culprit.
Pregnant women whose household tap water had higher levels of lithium had a moderately higher risk of their offspring being diagnosed with autism spectrum disorder, researchers reported in JAMA Pediatrics.
More than 1 million Californians live near active oil or gas wells, potentially exposing them to drilling-related pollution that can contribute to asthma, preterm births and a variety of other health problems.
Juvenile dermatomyositis, a rare but often severe and chronic systemic autoimmune disease, includes a large number of patients who are treatment resistant, requiring long term immunosuppressive therapy. A small open-label study published in Arthritis and Rheumatology shows promise using a targeted biologic therapy called abatacept to treat such patients.
In an analysis of more than 415,00 electronic health records of healthy, full-term births in Southern California, a team of researchers led by the University of California, Irvine determined that exposure to green space and tree coverage was associated with a decreased risk of postpartum depression among mothers.
In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.
Clemson University researchers have identified an enzyme and its products in humans that reduce diet-induced obesity.
Algal blooms or cylindrospermopsin, exacerbated by climate change, shown to have a connection with several adverse health effects.
MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state.
A six-month study led by Johns Hopkins Medicine researchers concludes that the use of portable home air purifiers can improve some markers of cardiovascular health in people with chronic obstructive pulmonary disease, or COPD
A new animal study points to a gene that is important for the earliest development of basic social behaviors.
Researchers have demonstrated in mice a new approach for delivering medication across the blood-brain barrier to treat tumors that cause aggressive, lethal brain cancer.
The U.S. has the world’s largest population of prisoners, and Texas holds more incarcerated people than any other state.
A novel metric that estimates our “burden,” or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.
Wayne State University has received a five-year, approximately $11.3 million award from the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health to create a new Superfund Research Program, the “Center for Leadership in Environmental Awareness and Research (CLEAR).” The Center will be dedicated to understanding and mitigating adverse birth outcomes and serious developmental health problems that have been associated with urban environmental exposure to volatile organic chemcials (VOCs), a special class of pollutant found in the subsurface of post-industrial cities like Detroit.
The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.
Per- and polyfluoroalkyl substances (PFAS) and phthalates (two types of endocrine-disrupting chemicals) may be associated with lower bone mineral density in male teens, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism.
Eight substances have been added to the Report on Carcinogens, bringing the total list to 256 substances that are known, or reasonably anticipated, to cause cancer in humans. This is the 15th Report on Carcinogens, which is a cumulative report, mandated by Congress and prepared by the National Toxicology Program (NTP).
Use of certain personal care products during pregnancy may impact maternal hormone levels, according to a new Rutgers study.
Researchers at the National Institutes of Health have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. The method involves white blood cells of the immune system called macrophages that eat bacteria, and a group of compounds that are naturally produced in mice and humans.
Vaping aerosols contain thousands of unknown chemicals and substances not disclosed by manufacturers, including industrial chemicals and caffeine, Johns Hopkins University researchers found.
A Florida State University researcher will lead a study into how bacteria can be used to remove carcinogens from groundwater thanks to a $1.4 million grant from the National Institute of Environmental Health Sciences.
New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor. The study in mice — published online in the Proceedings of the National Academy of Sciences — provides novel insights for developing treatments.
The mosquito protein AEG12 strongly inhibits the family of viruses that cause yellow fever, dengue, West Nile, and Zika and weakly inhibits coronaviruses, according to scientists at the National Institutes of Health and their collaborators. They found that AEG12 works by destabilizing the viral envelope, breaking its protective covering.
DNA sequencing of bacteria found in pigs and humans in rural eastern North Carolina, an area with concentrated industrial-scale pig-farming, suggests that multidrug-resistant Staphylococcus aureus strains are spreading between pigs, farmworkers, their families and community residents, and represents an emerging public health threat, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19.
Children in low-income neighborhoods in Baltimore tended to have more asthma symptoms when levels of the synthetic chemical BPA (Bisphenol A) in their urine were elevated, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health and School of Medicine.
Researchers from the UCLA Fielding School of Public Health have found that pregnant women exposed to high levels of ultrafine particles from jet airplane exhaust are 14% more likely to have a preterm birth than those exposed to lower levels.
UCLA & USC study of natural gas flaring finds high risks to babies; researchers found exposure was associated with 50% higher odds of preterm birth compared with no exposure.
Today on World Asthma Day, the National Institutes of Health stands with patients, families, advocates, researchers, and health care professionals to raise awareness about this common chronic respiratory disease, the people it affects, and the research that improves its prevention and treatment.
Why do some people feel like they need three cups of coffee just to get through the day when others are happy with only one? Why do some people abstain entirely? New research suggests that our intake of coffee – the most popular beverage in America, above bottled water, sodas, tea, and beer – is affected by a positive feedback loop between genetics and the environment.
There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules — a signaling channel that’s found in a tiny organ on the side of your neck — effectively lowers blood pressure in obese mice, the researchers reported recently in the journal Circulation Research.
A potential carcinogen that has been banned as a food additive is present in concerningly high levels in electronic cigarette liquids and smokeless tobacco products, according to a new study from Duke Health.
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