Curated News: National Institutes of Health (NIH)

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Embargo will expire: 31-Mar-2020 9:00 AM EDT Released to reporters: 26-Mar-2020 12:10 PM EDT

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Released: 26-Mar-2020 10:30 AM EDT
How Errors in Divvying Up Chromosomes Lead to Defects in Cells
NIH, National Institute of General Medical Sciences (NIGMS)

During the fundamental process of mitosis, a type of cell division, dividing cells sometimes make errors while divvying up chromosomes. Understanding how this happens may help researchers develop targeted therapies for a variety of diseases, including cancer.

Newswise: Experiments in Mice And Human Cells Shed Light On Best Way to Deliver Nanoparticle Therapy For Cancer
Released: 26-Mar-2020 8:00 AM EDT
Experiments in Mice And Human Cells Shed Light On Best Way to Deliver Nanoparticle Therapy For Cancer
Johns Hopkins Medicine

Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively — allowing the nanoparticles to diffuse into tumors and become held in place, or actively — adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. Now, new research on human and mouse tumors in mice by investigators at the Johns Hopkins Kimmel Cancer Center suggests the question is even more complicated.

Newswise: Supercomputer Helps Benchmark Cancer Immunotherapy Tool
Released: 24-Mar-2020 3:35 PM EDT
Supercomputer Helps Benchmark Cancer Immunotherapy Tool
University of California San Diego

With an estimated 1.7 million new cases and 600,000 deaths during 2017 in the U.S. alone, cancer remains a critical healthcare challenge. Researchers used the Comet supercomputer at the San Diego Supercomputer Center (SDSC) to evaluate their new molecular docking tool which aims to improve immunotherapy outcomes by identifying more effective personalized treatments.

Released: 24-Mar-2020 2:50 PM EDT
UC San Diego Health Launches Clinical Trial to Assess Antiviral Drug for COVID-19
University of California San Diego Health

Researchers at four University of California Health medical centers have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, a drug that has shown promising activity against multiple viruses.

Newswise: The director of NIH visits UAB as COVID-19 appears
Released: 24-Mar-2020 2:30 PM EDT
The director of NIH visits UAB as COVID-19 appears
University of Alabama at Birmingham

Francis Collins, M.D., Ph.D., director of the NIH, flew to Birmingham on Thursday, March 5, to start a long-anticipated visit to UAB. Collins soon learned he had a problem back home. Maryland public health officials were reporting the first two cases of COVID-19 in the county where the NIH sits.

Released: 24-Mar-2020 11:35 AM EDT
Lack of media skepticism tied to belief in rape myths
Cornell University

People who tend to recognize similarities between people they know and people depicted in the media are more likely to believe common myths about sexual assault, according to a new study co-led by a Cornell researcher.

Newswise: Five language outcome measures evaluated for intellectual disabilities studies
23-Mar-2020 8:30 AM EDT
Five language outcome measures evaluated for intellectual disabilities studies
UC Davis Health

Expressive language sampling yielded five language-related outcome measures that may be useful for treatment studies in intellectual disabilities, especially fragile X syndrome. The measures were generally valid and reliable across the range of ages, IQs and autism symptom severity of participants. According to the study, led by UC Davis researchers and funded by NIH, the measures are also functional in supporting treatments that can improve language, providing far reaching benefits for individuals with intellectual disabilities.

Released: 23-Mar-2020 9:30 AM EDT
CEL-SCI to Develop LEAPS COVID-19 Immunotherapy in Collaboration with University of Georgia Center for Vaccines and Immunology
Cel-Sci Corp

Initial studies with COVID-19 coronavirus aim to replicate prior successful preclinical experiments of LEAPS against H1N1pandemic flu in mice conducted with National Institutes for Allergies and Infectious Diseases (NIAID)

Newswise: Immunotherapy using ‘young cells’ offers promising option against cancer
Released: 20-Mar-2020 6:05 PM EDT
Immunotherapy using ‘young cells’ offers promising option against cancer
Washington University in St. Louis

A new study from Washington University School of Medicine in St. Louis suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells — natural killer (NK) cells — appear to be more effective the earlier they are in development, opening the door to the possibility of an immunotherapy that would not utilize cells from the patient or a matched donor. Instead, they could be developed from existing supplies of what are called human pluripotent stem cells.

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