Feature Channels: Parkinson’s Disease

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7-Jan-2022 1:05 PM EST
Study: Get Moving to Put the Brakes on Early Parkinson’s
American Academy of Neurology (AAN)

A new study suggests that people with early-stage Parkinson’s disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily activities later. The research is published in the January 12, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that those who exercised regularly over five years did better on cognitive tests and had slower progression of the disease in several aspects.

Newswise: Can a Human Microglial Atlas Guide Brain Disorder Research?
4-Jan-2022 8:00 AM EST
Can a Human Microglial Atlas Guide Brain Disorder Research?
Mount Sinai Health System

Mount Sinai researchers analyzed thousands of microglia from different brain regions of deceased patients who had been diagnosed with a variety of neuropsychiatric and neurodegenerative disorders. Their results, published in Nature Genetics, support the idea that microglia may play critical roles in some cases of brain disease while also providing a potentially valuable guide for future studies.

Newswise: SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation
Released: 14-Dec-2021 12:35 PM EST
SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation
American Chemical Society (ACS)

Researchers reporting in ACS Chemical Neuroscience have shown that, at least in the test tube, the SARS-CoV-2 N-protein interacts with a neuronal protein called α-synuclein and speeds the formation of amyloid fibrils, pathological protein bundles that have been implicated in Parkinson’s disease.

Newswise: UC San Diego Helps Expand Parkinson’s Progression Markers Initiative
Released: 6-Dec-2021 1:05 PM EST
UC San Diego Helps Expand Parkinson’s Progression Markers Initiative
University of California San Diego Health

UC San Diego School of Medicine partners with The Michael J. Fox Foundation on a clinical study to identify biomarkers of Parkinson’s disease. The study seeks to recruit 4,000 participants by the end of 2023.

Newswise: Compound shows promise for minimizing erratic movements in Parkinson’s patients
Released: 1-Dec-2021 2:00 PM EST
Compound shows promise for minimizing erratic movements in Parkinson’s patients
Texas Biomedical Research Institute

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson’s disease.

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Released: 29-Nov-2021 8:30 AM EST
Richard S. Isaacson, M.D., Joins FAU to Lead Alzheimer’s Disease Prevention
Florida Atlantic University

Isaacson will lead an academic clinical research program aimed at reducing the risk of Alzheimer’s disease (AD), Parkinson’s disease, and Lewy body dementia in individuals with a family history of these diseases who do not yet have any cognitive decline or other clinical complaints.

15-Nov-2021 2:35 PM EST
AAN Issues Guideline for Treatment of Early Parkinson’s Disease
American Academy of Neurology (AAN)

The American Academy of Neurology (AAN) has issued a guideline providing recommendations for treating movement symptoms, called motor symptoms, in people with early Parkinson’s disease. The guideline is published in the November 15, 2021, online issue of Neurology®, the medical journal of the AAN, and is endorsed by the Parkinson’s Foundation. This guideline updates recommendations on dopaminergic medications that were published in the 2002 AAN guideline on the initiation of treatment for Parkinson’s disease.

11-Nov-2021 1:35 PM EST
Vascular Defects Appear to Underlie the Progression of Parkinson’s Disease
Georgetown University Medical Center

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson’s disease. The finding could help explain an earlier outcome of the same study, in which the drug nilotinib was able to halt motor and non-motor (cognition and quality of life) decline in the long term.

22-Oct-2021 3:35 PM EDT
Study: Death Rate from Parkinson’s Rising in U.S.
American Academy of Neurology (AAN)

A new study shows that in the last two decades the death rate from Parkinson’s disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that the death rate was twice as high in men as in women, and there was a higher death rate in white people than other racial/ethnic groups.

Newswise: UC San Diego-Led Team Receives $9M to Advance Parkinson’s Disease Treatments
Released: 27-Oct-2021 2:50 PM EDT
UC San Diego-Led Team Receives $9M to Advance Parkinson’s Disease Treatments
University of California San Diego Health

A new $9 million grant from Aligning Science Across Parkinson’s (ASAP) will enable advancement of UC San Diego’s discovery that inhibiting a single gene in mice converts other cell types directly into new neurons, alleviating all Parkinson’s symptoms.

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Released: 27-Oct-2021 10:00 AM EDT
Gut-Brain Connection Research Gets Boost of $8.9 Million
Johns Hopkins Medicine

Johns Hopkins Medicine is one of three research institutions with scientists awarded $8.9 million to study the growing body of evidence that Parkinson’s disease originates among cells in the gut and travels up the body’s neurons to the brain. The research aims to develop treatments to prevent or halt progression of the disease.

Newswise: Rutgers Researchers Find Links to Genetic Disorders in Walking Patterns
Released: 22-Oct-2021 11:10 AM EDT
Rutgers Researchers Find Links to Genetic Disorders in Walking Patterns
Rutgers University-New Brunswick

Rutgers researchers have linked the genetic disorders Fragile X and SHANK3 deletion syndrome – both linked to autism and health problems – to walking patterns by examining the microscopic movements of those wearing motion-sensored sneakers.

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Released: 19-Oct-2021 4:45 PM EDT
Study Reveals Motor Cortex Could Have Larger Role in Parkinson’s Disease
Stony Brook University

Researchers at Stony Brook University demonstrated that a loss of midbrain dopaminergic centers impairs the ability of the primary motor cortex neurons to transform inputs into appropriate output. The finding, published in eNeuro, supports a new line of research on the role of the motor cortex in Parkinson's Disease.

Released: 11-Oct-2021 9:00 AM EDT
NYU Langone Health Launches Parekh Center for Interdisciplinary Neurology to Accelerate Scientific Discovery
NYU Langone Health

NYU Langone’s Parekh Center for Interdisciplinary Neurology will accelerate research of neurodegenerative conditions across the institution thanks to a significant philanthropic gift.

Released: 8-Oct-2021 4:55 PM EDT
Frontrunner target for Parkinson’s Disease may only be relevant for small fraction of patients
University of Copenhagen, Faculty of Health and Medical Sciences

Parkinson’s Disease develops if a certain anti-viral receptor and its protein in the brain, called the interferon-beta pathway, is not functioning correctly.

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Released: 6-Oct-2021 11:00 AM EDT
Neuroscientists map major circuit in the mouse brain
University of California, Los Angeles (UCLA), Health Sciences

A UCLA study reveals new insights into the wiring of a major brain circuit that is attacked by Parkinson’s and Huntington’s disease. The findings could hone scientists’ understanding of how diseases arise in the human brain and pinpoint new therapeutic targets.

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Released: 5-Oct-2021 1:55 PM EDT
A new view of Parkinson’s disease
Texas A&M AgriLife

More than 10 million people worldwide have Parkinson’s disease, which is progressively debilitating and, at present, incurable. Now, Texas A&M AgriLife researchers have found a new way to study the disorder’s progression on a molecular level. The team has also obtained new clues toward a treatment.

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Released: 5-Oct-2021 1:40 PM EDT
$35 million to support study of sleep disorder linked to neurodegeneration
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis, Mayo Clinic in Rochester, Minn., and The Neuro (Montreal Neurological Institute-Hospital) of McGill University have received a five-year grant expected to total $35.1 million for an extension of a study designed to develop biomarkers that indicate which people with the sleep disorder will go on to develop neurodegenerative diseases.

Released: 5-Oct-2021 1:10 PM EDT
Sleep disorder linked to neurodegeneration aim of NIH-funded grant
Mayo Clinic

People with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball or try to run from an illusory assailant.

29-Sep-2021 7:00 AM EDT
New Treatments for Alzheimer’s and Stroke Revealed in Several New Studies
American Physiological Society (APS)

The results of three new studies indicate there could be new treatments for Alzheimer’s and stroke.

Newswise: Early-Stage Drug Candidate Diminishes Deficits in Parkinson’s Disease
Released: 22-Sep-2021 6:10 PM EDT
Early-Stage Drug Candidate Diminishes Deficits in Parkinson’s Disease
University of Utah Health

University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease. Its discovery points toward a new strategy for treating the disease and potentially stopping its progression.

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Released: 21-Sep-2021 5:10 PM EDT
Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression in Lab Study
Rush University Medical Center

Rush researchers have shown that two lab-developed and nasally-delivered peptides helped slow the spread of alpha-synuclein in mice.

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Released: 20-Sep-2021 1:15 PM EDT
UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel Institute
University of Florida

The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.

Released: 16-Sep-2021 12:40 PM EDT
Mayo y Google Research crean nuevo algoritmo de inteligencia artificial para mejorar dispositivos de estimulación cerebral y tratar enfermedades
Mayo Clinic

La estimulación cerebral amplía las alternativas de tratamiento para millones de personas que sufren de epilepsia y otros trastornos del movimiento, como la enfermedad de Parkinson.

Newswise: Jersey Shore University Medical Center Welcomes Shabbar Danish, MD, as Chair of Neurosurgery
Released: 13-Sep-2021 3:05 PM EDT
Jersey Shore University Medical Center Welcomes Shabbar Danish, MD, as Chair of Neurosurgery
Hackensack Meridian Health

Hackensack Meridian Jersey Shore University Medical Center recently welcomed Board Certified Neurosurgeon Shabbar F. Danish, M.D., FAANS, as Chair of Neurosurgery as part of the academic medical center’s Neuroscience Institute.

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Released: 13-Sep-2021 1:25 PM EDT
Researchers Shed New Light on Molecular Mechanisms in Brain Diseases
Rutgers University-New Brunswick

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

2-Sep-2021 1:35 PM EDT
People with Parkinson’s May Benefit from 7 Walking Strategies
American Academy of Neurology (AAN)

Various strategies can help people with Parkinson’s who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The research is published in the September 8, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that how well different compensation strategies worked depended on the context in which they were used, such as indoors versus outdoors, under time pressure or not.

Released: 3-Sep-2021 12:20 PM EDT
Mayo, Google Research develop new AI algorithm to improve brain stimulation devices to treat disease
Mayo Clinic

For millions of people with epilepsy and movement disorders such as Parkinson's disease, electrical stimulation of the brain already is widening treatment possibilities. In the future, electrical stimulation may help people with psychiatric illness and direct brain injuries, such as stroke.

Newswise: Old Habit-Controlling Neurons May Also Help the Brain Learn New Tricks
Released: 26-Aug-2021 2:20 AM EDT
Old Habit-Controlling Neurons May Also Help the Brain Learn New Tricks
Mount Sinai Health System

In a study of rodents, scientists at the Icahn School of Medicine at Mount Sinai discovered that a part of the brain traditionally thought to control typing the old habits may also play a critical role in learning the new actions. The results, published on August 25th in Nature Communications, suggest that this process involves a delicate balance in the activity of two neighboring neural circuits: one dedicated to new actions and the other to old habits

Newswise:Video Embedded first-atomic-level-imaging-of-lethal-prions-provide-sharpened-focus-for-potential-treatments
VIDEO
20-Aug-2021 6:00 PM EDT
First atomic-level imaging of lethal prions provide sharpened focus for potential treatments
Case Western Reserve University

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals—and how they can be potentially targeted by new therapies.

Newswise:Video Embedded breakthrough-cases-and-covid-boosters-live-expert-panel-for-august-18-2021
VIDEO
Released: 19-Aug-2021 3:00 PM EDT
VIDEO AND TRANSCRIPT AVAILABLE: Breakthrough Cases and COVID Boosters: Live Expert Panel for August 18, 2021
Newswise

Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.

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VIDEO
Released: 13-Aug-2021 12:25 PM EDT
Mount Sinai Partners With Studio Elsewhere to Launch Q-Lab, an Immersive, Interactive Research and Restorative Care Environment for Deep Brain Stimulation Patients
Mount Sinai Health System

The use of artificial intelligence and machine learning enable new insights to help diagnose illness, suggest specific courses of treatment and follow patient’s progress

Newswise: Hopkins Med News Update
Released: 29-Jul-2021 11:00 AM EDT
Hopkins Med News Update
Johns Hopkins Medicine

NEWS STORIES IN THIS ISSUE: -Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction -Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia -Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium -Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis -Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development -COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID

Newswise: Fruit Compound May Have Potential to Prevent and Treat Parkinson’s Disease, Mouse Study Suggests
26-Jul-2021 10:25 AM EDT
Fruit Compound May Have Potential to Prevent and Treat Parkinson’s Disease, Mouse Study Suggests
Johns Hopkins Medicine

Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson’s disease in mouse studies.

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Released: 19-Jul-2021 11:05 AM EDT
Chemists Found an Effective Remedy For "Aged" Brain Diseases
Ural Federal University

Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies.

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Released: 8-Jul-2021 1:00 PM EDT
Identified an early neuronal dysfunction in Parkinson's that could help early diagnosis
University of Barcelona

Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

Released: 8-Jul-2021 12:35 PM EDT
Dancing with music can halt most debilitating symptoms of Parkinson's disease
York University

A new study published in Brain Sciences today, shows patients with mild-to-moderate Parkinson's disease (PD) can slow the progress of the disease by participating in dance training with music for one-and-a-quarter hours per week.

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7-Jul-2021 4:30 PM EDT
New Alzheimer’s Treatment Targets Identified
Washington University in St. Louis

A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs with therapeutic potential.

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Released: 1-Jul-2021 12:50 PM EDT
Discovery of nanosized molecules that might inhibit Alzheimer's and Parkinson's diseases
Umea University

Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues.

Newswise: Differences in human, mouse brain cells have important implications for disease research
Released: 25-Jun-2021 12:25 PM EDT
Differences in human, mouse brain cells have important implications for disease research
University of California, Los Angeles (UCLA), Health Sciences

A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

Newswise: Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19
Released: 24-Jun-2021 7:30 PM EDT
Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19
Henry Ford Health System

DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.

Newswise: Will Reduction in Tau Protein Protect Against Parkinson’s and Lewy Body Dementias?
Released: 18-Jun-2021 11:55 AM EDT
Will Reduction in Tau Protein Protect Against Parkinson’s and Lewy Body Dementias?
University of Alabama at Birmingham

A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.

Newswise:Video Embedded ohio-state-among-first-in-nation-to-implant-new-deep-brain-stimulation-device
VIDEO
Released: 14-Jun-2021 4:45 PM EDT
Ohio State Among First In Nation To Implant New Deep-Brain Stimulation Device
Ohio State University Wexner Medical Center

COLUMBUS, Ohio – The team of neurologists and neurosurgeons at The Ohio State University Wexner Medical Center and its Neurological Institute are among the first in the nation to implant a new deep-brain stimulation (DBS) device that will help improve the quality of life of patients with Parkinson’s disease.

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Released: 8-Jun-2021 3:20 PM EDT
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
Van Andel Institute

GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.

1-Jun-2021 8:00 PM EDT
After 15 Years, Deep Brain Stimulation Still Effective in People with Parkinson’s
American Academy of Neurology (AAN)

Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that compared to before deep brain stimulation, study participants continued to experience significant improvement in motor symptoms, which are symptoms that affect movement, as well as a reduction in medications 15 years later.


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