Feature Channels: Pharmaceuticals

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Digital Science solutions metaphacts and Dimensions announce the launch of the Dimensions Knowledge Graph, a large ready-made knowledge graph powering AI solutions in the pharmaceutical and life sciences industries.

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The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A Monell team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications.

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Recent work by St. Jude Children’s Research Hospital scientists discovered which tumor cells resist treatment and why. By characterizing B-cells’ developmental stages, they designed and tested a drug combination to effectively treat resistant B-cell leukemia.

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Researchers have developed an automated workflow that could accelerate the discovery of new pharmaceutical drugs and other useful products. The new approach could enable real-time reaction analysis and identify new chemical-reaction products much faster than current laboratory methods.

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The common painkiller acetaminophen was found to alter proteins in the heart tissue when used regularly at moderate doses, according to a new study conducted in mice. Researchers will present their work this week at the American Physiology Summit in Long Beach, California.

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Pharmacists are being recognised for their vital role in supporting home-based rural palliative care patients, as new research shows that they not only enable patients to choose to stay at home, but also provide significant relief, comfort, and peace of mind for patients, carers, and family members.

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Cystic fibrosis is the most common, life-limiting genetic condition in Australia. It affects the lungs, digestive system, and reproductive system, producing excess mucus, infections, and blockages.

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University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Martine Rothblatt PhD, JD, MBA, Chairperson and CEO of United Therapeutics, and inventor of SiriusXM Satellite Radio, will deliver the keynote address for this year’s graduating medical student class. The UMSOM MD graduation ceremony will take place at the Hippodrome Theatre on Thursday, May 16, 2024.

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A team of scientists led by Prof Guillermo Bazan from NUS Institute for Functional Intelligent Materials (I-FIM) has developed a novel antibiotic named COE-PNH2 that is capable of combating hard-to-treat mycobacterial lung infections.

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A newly developed compound is showing promise in animal studies as a more effective treatment for human schistosomiasis, an understudied tropical disease caused by parasitic worms.

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Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.

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An artificial intelligence tool West Virginia University health data scientists are developing could lessen medication errors that send recently discharged patients back to the hospital while reducing health care costs.

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“Today, we at the Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC) provided testimony to Congress regarding the impact of the Food and Drug Administration’s (FDA’s) proposed rule to impose FDA oversight on laboratory developed tests in addition to Centers for Medicare & Medicaid Services (CMS) oversight. While we share FDA’s goal of ensuring that laboratory developed tests are safe and effective, we have serious concerns about the agency’s proposal. If finalized, this rule would create a burdensome dual regulatory structure that would limit patient access to many life-saving tests.

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The use of vitamin supplements is on the rise in the U.S. But do they do any good? A Penn State Health expert talks about the benefits and pitfalls.

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Prostate cancer patients receiving care at hospitals that are part of a special drug-pricing program were more likely to stick to their prescription drug therapy than patients at other hospitals, according to a study from researchers at the University of Michigan’s Rogel Cancer Center and Institute for Healthcare Policy and Innovation.

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The collaboration between Philadelphia College of Osteopathic Medicine (PCOM) and The Wistar Institute has resulted in the creation of a PhD program in Cancer Biology, preparing individuals for careers in cancer research and drug development.

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Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan and Jiangnan University in Wuxi, China.

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A global wave of infections caused by fungi growing drug-resistant has the medical community issuing precautions on how to protect yourself.

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Radyus Research partners with Southern Research for an innovative alliance in the development of new drugs.

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An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.

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In a new study, Sanford Burnham Prebys researchers, led by Andrei L. Osterman, Ph.D., combined experimental evolution in a continuous culturing device with whole genome sequencing of evolving cultures to track how two bacterial pathogens acquired drug resistance against a pair of antibiotics, one long-used and the other experimental.

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Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues. UTSW received another $6 million for recruitment efforts.

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New research shows HIV medications can be taken at the same time as hormone treatment without losing potency of either therapy.

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Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.

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The FDA has approved two medications for the treatment of eosinophilic esophagitis (EoE)—the first oral medication tailored for adults and the exclusive therapeutic option for children. Evan Dellon, MD, MPH, internationally known for his work with EoE, and colleagues continue to focus on optimizing usage for effective, personalized outcomes.

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Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.

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Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.

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A subpopulation of gut bacteria given a commonly used antibiotic became "persisters" that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered. Their findings, published in Cell Host & Microbe, could lead to better ways to fight bacterial infections.

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Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.

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Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.

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RUDN University doctors demonstrated the capabilities of a new method for remote analysis of drugs in packaging and after entering the body. They can be assessed using radio thermal emission of nanoparticles in drugs. Scientists were able to check the suitability of the medicine without opening the packaging or monitor it inside the body.

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Calls to U.S. poison centers involving psilocybin, or “magic mushrooms,” among adolescents and young adults rose sharply after several U.S. cities and states began decriminalizing the hallucinogen, University of Virginia School of Medicine researchers have found.

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To provide a clear picture of opioid manufacture and travel, the University of Notre Dame developed a user-friendly interface to enable public access to more than 10 years of national controlled substance transaction information. This platform makes querying easier and faster, providing transactional data on 14 different opioids including fentanyl, hydrocodone and oxycodone.

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Diabetic patients who take anti-diabetic drugs - known as glitazones – long term had a lower risk of primary and secondary brain cancer compared with diabetic patients on other medications, new research led by the University of Bristol has found.

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Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.

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An online pharmacy offering standardized, transparent pricing can reduce out-of-pocket costs for patients taking common medications prescribed by urologists, suggests a study in the March issue of Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.