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Released: 10-Jul-2020 2:20 PM EDT
Nephron Pharmaceuticals Corporation Announces Historic Expansion in Lexington County
Nephron Pharmaceuticals Corporation

One of the fastest-growing pharmaceuticals companies in the country, headquartered in Lexington County, today announced several major expansion and investment projects.

Released: 10-Jul-2020 11:30 AM EDT
Scientists may have found one path to a longer life
University of Southern California (USC)

Scientists at USC Dornsife College of Letters, Arts and Sciences may have found the beginnings of a path toward increasing human lifespan.

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Embargo will expire: 13-Jul-2020 2:00 PM EDT Released to reporters: 9-Jul-2020 10:50 AM EDT

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Released: 9-Jul-2020 9:30 AM EDT
San Antonio Partnership for Precision Therapeutics Fuels COVID-19 Research
Texas Biomedical Research Institute

Fueling transformative research through collaboration, the San Antonio Partnership for Precision Therapeutics (SAPPT) announces the funding of three more collaborative COVID-19 research efforts in San Antonio. SAPPT has awarded more than $600,000 to fund these projects, following the funding of a SARS CoV-2 vaccine project announced in April of this year.

Newswise: Experimental drug shows early promise against inherited form of ALS, trial indicates
8-Jul-2020 8:55 AM EDT
Experimental drug shows early promise against inherited form of ALS, trial indicates
Washington University in St. Louis

A clinical trial conducted at Washington University School of Medicine in St. Louis and other sites has found evidence that the experimental drug tofersen lowers levels of a disease-causing protein in people with an inherited form of amyotrophic lateral sclerosis, or ALS, caused by mutations in the gene SOD1.

Released: 8-Jul-2020 2:05 PM EDT
Mount Sinai Researcher Receives NIH Award to Study Immune Responses of Patients With Inflammatory Skin Diseases in the Setting of COVID-19 Infection
Mount Sinai Health System

The study will aim to understand whether systemic medications and biologics, such as dupilumab—a monoclonal antibody that binds to an inflammatory molecule, IL-4 receptor alfa, and inhibits the inflammatory response that leads to rashes and itching from atopic dermatitis/eczema—may have a positive or negative impact on COVID-19 responses in patients who have the disease.

Released: 8-Jul-2020 1:45 PM EDT
Study Finds Patients Who Undergo Spine Surgery Prescribed Most Narcotics Three Months Following Surgery
American Academy of Orthopaedic Surgeons (AAOS)

As Americans have the highest opioid use rates, leading to abuse, the orthopaedic community has committed itself to studying prescription methods and patient populations to help mitigate potential addiction. A new scientific review article titled, “Ninety-day Postoperative Narcotic Use After Hospitalization for Orthopaedic Trauma,” published in the July issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), found a correlation between patient-reported pain at discharge from inpatient surgery and the number of opioids prescribed during the 90-day postoperative period.

Newswise:Video Embedded pandemic-could-make-drug-resistance-epidemic-worse
VIDEO
Released: 8-Jul-2020 11:50 AM EDT
Pandemic could make drug resistance epidemic worse
University of Georgia

Researchers fear that widespread use of antibiotics during the coronavirus pandemic will add fuel to the fire, making more common infections that were once treatable possibly life threatening.

Newswise: New book examines human right to health, pushes for rating system for pharmaceutical companies
Released: 8-Jul-2020 10:05 AM EDT
New book examines human right to health, pushes for rating system for pharmaceutical companies
Binghamton University, State University of New York

Every human being has the right to health and new initiatives should be put in place to encourage pharmaceutical companies to ensure that everyone has access to essential medicine, according to a new book from Nicole Hassoun, professor of philosophy at Binghamton University, State University of New York.

Newswise: Aspirin, flavonoid metabolites may be preventing colorectal cancer
Released: 7-Jul-2020 5:15 PM EDT
Aspirin, flavonoid metabolites may be preventing colorectal cancer
South Dakota State University

Simpler phenolic compounds, known as hydroxybenzoic acids, that result when the gut bacteria break down aspirin and flavonoids from fruits and vegetables may contribute to colorectal cancer prevention.

Released: 7-Jul-2020 5:10 PM EDT
Policies fall short on expanding access to birth control
University of Illinois at Chicago

Only 10.1% of Los Angeles County pharmacies provided this service and 77.4% imposed age-restrictions at 18 years or older, including in neighborhoods with the highest rates of unintended pregnancies and teen births.

Released: 7-Jul-2020 2:00 PM EDT
Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors (PPIs)
American College of Gastroenterology (ACG)

Findings from an online survey of more than 53,000 American adults suggest that using heartburn medications known as proton pump inhibitors (PPIs) once or twice daily significantly increases the odds of a positive test for COVID-19 compared to those who do not take PPIs. This research appeared online July 7, 2020 in pre-print format in The American Journal of Gastroenterology.

Newswise: Seaver Autism Center For Research and Treatment at Mount Sinai Launches First Drug Trial for ADNP Syndrome
Released: 7-Jul-2020 1:55 PM EDT
Seaver Autism Center For Research and Treatment at Mount Sinai Launches First Drug Trial for ADNP Syndrome
Mount Sinai Health System

Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have started recruiting participants for a new clinical trial to evaluate the safety, tolerability, and efficacy of a low dose of ketamine in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

Released: 7-Jul-2020 12:50 PM EDT
Remdesivir can save more lives where ICUs are overwhelmed
Boston University School of Medicine

Amid news that the United States has bought up virtually the entire global supply of remdesivir, a new Boston University School of Public Health (BUSPH) study outlines how the drug could save lives in countries with less hospital capacity, such as South Africa, where COVID-19 is beginning to overwhelm intensive care units (ICUs).

Newswise: A New Understanding of Protein Movement
Released: 7-Jul-2020 12:20 PM EDT
A New Understanding of Protein Movement
University of Delaware

A team of UD engineers has uncovered the role of surface diffusion in protein transport, which could aid biopharmaceutical processing. This work will lead to the creation of new ways to reduce waste during the expensive drug manufacturing process, enabling more efficient ways of designing and developing manufacturing techniques.

Newswise: Towards improved wound healing – Chemical synthesis of a trefoil factor peptide
Released: 7-Jul-2020 8:55 AM EDT
Towards improved wound healing – Chemical synthesis of a trefoil factor peptide
University of Vienna

Milestone for therapeutic development of peptides against gastrointestinal disordersThe fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn’s disease. For the first time, a team led by ERC awardee Markus Muttenthaler from the Faculty of Chemistry of the University of Vienna succeeded in the synthesis and folding of the peptide TFF1, a key player in mucosal protection and repair.

Released: 6-Jul-2020 1:40 PM EDT
US hydroxychloroquine, chloroquine, azithromycin outpatient prescriptions October 2019-March 2020
JAMA - Journal of the American Medical Association

What The Study Did: How the prescription of hydroxychloroquine and chloroquine to outpatients has changed in the United States during the COVID-19 pandemic is examined in this study.

29-Jun-2020 9:00 AM EDT
Patients may be exposed to hormone-disrupting chemicals in medication, medical supplies
Endocrine Society

Health care providers may unintentionally expose patients to endocrine- disrupting chemicals (EDCs) by prescribing certain medications and using medical supplies, according to a perspective published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Released: 1-Jul-2020 3:35 PM EDT
Study shows asthma drug salbutamol's potential as Alzheimer's treatment
Lancaster University

A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer's disease.

Released: 1-Jul-2020 2:25 PM EDT
Financial Conflicts of Interest Are Often Not Disclosed in Spinal Surgery Journals
Wolters Kluwer Health: Lippincott Williams and Wilkins

Many studies published by major spinal surgery journals do not include full disclosure of researchers’ financial conflicts of interest (COIs), reports a study in Spine. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Newswise: New Drug Reduces Stroke Damage in Mice
29-Jun-2020 12:35 PM EDT
New Drug Reduces Stroke Damage in Mice
Health Sciences at the University of Pittsburgh

Mice that received an injection of a new experimental drug, TAT-DP-2, after a stroke had smaller areas of damage, and their long-term neurological function was better than that of untreated animals.

Newswise: More than medicine: pain-relief drug delivers choices for mothers in labour
Released: 30-Jun-2020 8:05 PM EDT
More than medicine: pain-relief drug delivers choices for mothers in labour
University of South Australia

Choice and control are important factors for ensuring a positive childbirth experience, yet until recently, little was known about the impact of alternative administrations of fentanyl – one of the pain relief drugs used during labour– on both mother and baby.

Newswise: UTEP Research Reveals More About Path Bacterial Pathogen Travels to Cause Tuberculosis
Released: 30-Jun-2020 4:55 PM EDT
UTEP Research Reveals More About Path Bacterial Pathogen Travels to Cause Tuberculosis
University of Texas at El Paso

Jianjun Sun, Ph.D., associate professor in UTEP’s Department of Biological Sciences, led the research on Mycobacterium tuberculosis (Mtb). Sun’s lab has been investigating the mechanisms of Mtb pathogenesis for more than 10 years at UTEP with a specific focus on EsxA, which is a virulence factor essential for Mtb virulence and a preferred target for developing novel anti-TB drugs and vaccines.

Released: 30-Jun-2020 9:50 AM EDT
Electrochemical reaction powers new drug discoveries
Cornell University

A Cornell-led collaboration is flipping the switch on traditional synthetic chemistry by using electricity to drive a new chemical reaction that previously stumped chemists who rely on conventional methods.

Newswise: Researchers Identify Multiple Molecules that Shut Down SARS-Cov-2 Polymerase Reaction
Released: 30-Jun-2020 8:55 AM EDT
Researchers Identify Multiple Molecules that Shut Down SARS-Cov-2 Polymerase Reaction
Columbia University School of Engineering and Applied Science

Researchers at Columbia Engineering and the University of Wisconsin-Madison have identified a library of molecules that shut down the SARS-CoV-2 polymerase reaction, a key step that establishes the potential of these molecules as lead compounds to be further modified for the development of COVID-19 therapeutics. Five of these molecules are already FDA-approved for use in the treatment of other viral infections including HIV/AIDS, cytomegalovirus, and hepatitis B.

Newswise: USC Norris Comprehensive Cancer Center receives $5 million for cancer drug discoveries
Released: 29-Jun-2020 2:05 PM EDT
USC Norris Comprehensive Cancer Center receives $5 million for cancer drug discoveries
Keck Medicine of USC

USC Norris Comprehensive Cancer Center receives $5 million for cancer drug discoveries

Newswise: Poseidon Innovation Announces Funding for Three UC San Diego Researchers
Released: 26-Jun-2020 10:30 AM EDT
Poseidon Innovation Announces Funding for Three UC San Diego Researchers
University of California San Diego

UC San Diego and Deerfield Management created Poseidon Innovation to support researchers working to advance disease-curing therapeutics by funding early stage projects and expediting the drug-development cycle. Poseidon announces it is funding three researchers.

Released: 26-Jun-2020 8:55 AM EDT
Biocodex Microbiota Foundation Announces Open Call for 2020 US Research Grant Applications
Biocodex

The Biocodex Microbiota Foundation, an organization founded by Biocodex and committed to inspiring scientific projects that investigate the implication of microbiota in human health, has announced the open call for applications for its annual US research grant, now in its fourth year.

Newswise: WFIRM and Oracle Health Sciences collaborate to pair Body-on-a-Chip with advanced data analytics
Released: 25-Jun-2020 3:00 PM EDT
WFIRM and Oracle Health Sciences collaborate to pair Body-on-a-Chip with advanced data analytics
Wake Forest Baptist Health

The Wake Forest Institute for Regenerative Medicine (WFIRM) and Oracle Health Sciences have teamed as part of the Innovation Quarter’s iQ Healthtech Labs™ to develop a consortium of industry, government, and academic members that will study novel approaches to establishing the safety of new drugs that are nearing clinical investigation in humans and FDA approval.

Released: 25-Jun-2020 2:55 PM EDT
Promising treatment to slow kidney disease doesn’t prove out in clinical trial
Joslin Diabetes Center

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival. Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. A multi-institution randomized clinical trial of a drug used to control uric acid did not show the desired clinical benefits, but did give a very clear answer to an important scientific question.

Released: 24-Jun-2020 3:10 PM EDT
Use of continuous combined oral contraceptives demonstrates bone health benefits
North American Menopause Society (NAMS)

omen with premature ovarian insufficiency (POI) become estrogen deficient at an early age, which makes them more vulnerable to the loss of bone mineral density.

Released: 24-Jun-2020 11:30 AM EDT
Exploring Nature’s Treasure Trove of Helpful Compounds
NIH, National Institute of General Medical Sciences (NIGMS)

Compounds that plants, fungi, bacteria, and animals produce can sometimes help people as well. In fact, many medicines, molecules used in research, and other useful compounds originated in nature. Learn more about recent discoveries in the fascinating field of natural products research.

Newswise: One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice
18-Jun-2020 4:25 PM EDT
One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice
University of California San Diego Health

UC San Diego researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.

Released: 24-Jun-2020 8:50 AM EDT
Turning alcohol into key ingredients for new medicines
Ohio State University

Chemists have found a way to turn alcohol into amino acids, the building blocks of life.

Released: 23-Jun-2020 7:55 PM EDT
Global Summit on Interventional Pharmacoeconomics to Discuss Ways to Lower Drug Costs
University of Chicago Medical Center

The University of Chicago Medicine’s Center for Personalized Therapeutics is hosting a virtual summit from June 9 to July 1 to discuss interventional pharmacoeconomics.

Newswise: From bench to beach: Award-winning epilepsy researcher furthers understanding of how cannabidiol stops seizures
Released: 23-Jun-2020 1:55 PM EDT
From bench to beach: Award-winning epilepsy researcher furthers understanding of how cannabidiol stops seizures
International League Against Epilepsy

Lyndsey Anderson traveled halfway around the world to do epilepsy research in Sydney, Australia. Recently, she was awarded ILAE's 2020 Epilepsia Prize for Basic Science Research.

Newswise: Story Tips From Johns Hopkins Experts on COVID-19
Released: 23-Jun-2020 12:00 PM EDT
Story Tips From Johns Hopkins Experts on COVID-19
Johns Hopkins Medicine

It seems there will never be enough “thank you’s” for the incredible doctors, nurses, technicians and support staff members who are working around the clock to help patients with the dangerous coronavirus disease. Their dedication, determination and spirit enable Johns Hopkins to deliver the promise of medicine.

Released: 23-Jun-2020 10:55 AM EDT
Monoclonal Antibody Restores T-Cell Ability to Kill Cancer
Sbarro Health Research Organization (SHRO)

A new class of anticancer agents can restore the ability of cytotoxic T lymphocytes (CTLs) to infiltrate the tumor and kill target cells in patients with metastatic non-small cell lung cancer (mNSCLC).

Released: 22-Jun-2020 4:40 PM EDT
UTHealth joins trial of arthritis drug’s effect on COVID-19-induced cytokine storm
University of Texas Health Science Center at Houston

A drug is being studied for its effectiveness in treating a type of severe immune overreaction seen in patients with COVID-19-induced pneumonia by researchers at The University of Texas Health Science Center at Houston (UTHealth). The clinical trial is enrolling patients at Harris Health System’s Lyndon B. Johnson Hospital.

Newswise: Immune Cells Infiltrating Tumors May Play Bigger Cancer Role Than Previously Thought
Released: 22-Jun-2020 3:15 PM EDT
Immune Cells Infiltrating Tumors May Play Bigger Cancer Role Than Previously Thought
University of California San Diego Health

UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells’ response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making IRE1α an attractive target for drug development.

Newswise: Using microparticles to eradicate tuberculosis
Released: 22-Jun-2020 12:55 PM EDT
Using microparticles to eradicate tuberculosis
South Dakota State University

Loading microparticles with drugs designed to active the macrophages in which TB bacteria hide may lead to therapeutics that can treat drug-resistant and latent TB.

Newswise: Focused ultrasound shows promise against deadliest brain tumor
Released: 22-Jun-2020 11:05 AM EDT
Focused ultrasound shows promise against deadliest brain tumor
University of Virginia Health System

An innovative use of focused ultrasound is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers.

Newswise: Major US Trial Closes Showing No Benefit for Hydroxychloroquine in COVID-19
Released: 22-Jun-2020 9:55 AM EDT
Major US Trial Closes Showing No Benefit for Hydroxychloroquine in COVID-19
Vanderbilt University Medical Center

The Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease (ORCHID) trial stopped enrolling new patients based on the fourth scheduled interim analysis showing no evidence of benefit or harm.

Released: 19-Jun-2020 11:55 AM EDT
MMR vaccine could protect against the worst symptoms of COVID-19
American Society for Microbiology (ASM)

Administering the MMR (measles, mumps, rubella) vaccine could serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection, say a team of experts in this week's mBio, a journal of the American Society for Microbiology.

Newswise: Breakthrough discovery to transform prostate cancer treatment
Released: 19-Jun-2020 6:05 AM EDT
Breakthrough discovery to transform prostate cancer treatment
University of South Australia

A novel formulation of the prostate cancer drug abiraterone acetate – currently marketed as Zytiga - will dramatically improve the quality of life for people suffering from prostate cancer, as pre-clinical trials by the University of South Australia show the new formulation improves the drug’s effectiveness by 40 per cent.

Newswise: The State of U.S. Strategic Stockpiles
Released: 18-Jun-2020 7:20 PM EDT
The State of U.S. Strategic Stockpiles
Council on Foreign Relations (CFR)

The coronavirus pandemic has renewed attention on the Strategic National Stockpile, the nation’s emergency reserve of medical supplies. It’s just one of the stockpiles the United States maintains for economic and strategic purposes.


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