Curated News: The Lancet

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24-Jan-2023 4:15 PM EST
Ignoring Native American data perpetuates misleading white ‘deaths of despair’ narrative
University of California, Los Angeles (UCLA), Health Sciences

An increase in "deaths of despair" in recent decades has been frequently portrayed as a phenomenon affecting white communities, but a new analysis in The Lancet shows the toll has been greater on Native Americans.

Released: 26-Jan-2023 4:15 PM EST
Small Study Shows Promise for Antimalarial Monoclonal Antibody to Prevent Malaria
University of Maryland School of Medicine

monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a small group of healthy volunteers who were exposed to malaria in a challenge study, according to new research published in The Lancet Infectious Diseases by researchers at the University of Maryland School of Medicine (UMSOM).

Released: 25-Jan-2023 4:55 PM EST
Corona vaccine based on new technology tested in clinical study
Radboud University Medical Centre Nijmegen

A new COVID-19 vaccine based on a different platform than current vaccines on the market has been tested in humans for the first time by researchers at Radboud university medical center.

Released: 20-Jan-2023 7:00 PM EST
New hope for treatment of rare metabolic disease
Universität Leipzig

X-linked adrenoleukodystrophy (X-ALD) is the most common of a group of around 50 rare diseases of the white matter of the brain, the so-called leukodystrophies.

Released: 17-Jan-2023 12:45 PM EST
Mucosal antibodies in the airways provide durable protection against SARS-CoV-2
Karolinska Institute

High levels of mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months. Omicron infection generates durable mucosal antibodies, reducing the risk of re-infection.

Released: 12-Jan-2023 7:20 PM EST
Triple-drug therapy for post-transplant management of multiple myeloma
University of Chicago Medical Center

Promising results from an ongoing clinical trial a three-drug treatment may improve survival in patients with newly diagnosed multiple myeloma who have undergone preliminary treatment followed by a stem cell transplant.

Newswise: When battling multiple infections, infants and toddlers at higher risk of severe outcomes, study suggests
Released: 12-Jan-2023 3:00 PM EST
When battling multiple infections, infants and toddlers at higher risk of severe outcomes, study suggests
Corewell Health

Results of the 18-month study, published in Lancet Regional Health - Americas and led by Amit Bahl, M.D., M.P.H., emergency medicine with Corewell Health East, formerly Beaumont Health, showed that while omicron cases had the highest hospital admission rates among children ages 0 to 17, serious, even deadly, cases of illness were less likely during omicron than during the delta and alpha variants. In fact, the odds of severe disease were 65% lower during omicron compared to alpha.

Newswise: Study links specific outdoor air pollutants to asthma attacks in urban children
Released: 5-Jan-2023 4:00 PM EST
Study links specific outdoor air pollutants to asthma attacks in urban children
NIH, National Institute of Allergy and Infectious Diseases (NIAID)

Moderate levels of two outdoor air pollutants, ozone and fine particulate matter, are associated with non-viral asthma attacks in children and adolescents who live in low-income urban areas, a study funded by the National Institutes of Health has found.

Released: 5-Jan-2023 3:50 PM EST
Antibiotic residues in water a threat to human health
Karolinska Institute

Antibiotic residues in wastewater and wastewater treatment plants in the regions around China and India risk contributing to antibiotic resistance, and the drinking water may pose a threat to human health, according to a comprehensive analysis from Karolinska Institutet published in The Lancet Planetary Health.

Newswise: Machine Learning Tackles Long COVID
Released: 5-Jan-2023 11:05 AM EST
Machine Learning Tackles Long COVID
Lawrence Berkeley National Laboratory

There are so many unknowns about long COVID. Why is the range of symptoms so vast? How do pre-existing conditions play a role? Scientists have developed a machine learning tool to accelerate discoveries using actual patient data.

   
Newswise: Digital Marker for Coronary Artery Disease Built by Researchers at Mount Sinai
19-Dec-2022 7:00 PM EST
Digital Marker for Coronary Artery Disease Built by Researchers at Mount Sinai
Mount Sinai Health System

Using machine learning and clinical data from electronic health records, researchers at the Icahn School of Medicine at Mount Sinai in New York constructed an in silico, or computer-derived, marker for coronary artery disease (CAD) to better measure clinically important characterizations of the disease.

Released: 19-Dec-2022 12:00 PM EST
MD Anderson Research Highlights for December 19, 2022
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a cell cycle checkpoint inhibitor with potential therapeutic effects in an ovarian cancer subtype, a telementoring program for French-speaking oncology providers in Africa, insights into the relationship between obesity and immunotherapy side effects, updates to the world’s largest cancer drug discovery knowledgebase, improvements to treatment response by blocking the EGFR pathway, and a novel noninvasive diagnostic test for immunotherapy-related kidney injury.

   
Newswise: Noteworthy Medical Research Discoveries From 2022
Released: 7-Dec-2022 12:40 PM EST
Noteworthy Medical Research Discoveries From 2022
Cedars-Sinai

Investigators at Cedars-Sinai conduct more than 2,500 research projects annually, and many of these studies have resulted in new treatments or have opened the door to future innovations.

Released: 21-Nov-2022 3:15 PM EST
الفحص الموجه بالذكاء الاصطناعي يستخدم بيانات مخطط كهربية القلب لاكتشاف أحد عوامل الخطر الخفية للإصابة بالسكتة الدماغية
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا - استخدم باحثو مايو كلينك الذكاء الاصطناعي لتقييم مخططات كهربية القلب للمرضى في إطار استراتيجية استهدافيّة للكشف عن الرجفان الأذيني، وهو إحدى اضطرابات نظم القلب الشائعة. الرجفان الأذيني هو عدم انتظام ضربات القلب، والذي قد يؤدي إلى جلطات دموية قد تنتقل إلى الدماغ وتسبب سكتة دماغية؛ لكن لا يتم يُشخص بشكل صحيح في معظم الأحيان. في الدراسة اللامركزية الميسرة رقميًا، قام الذكاء الاصطناعي بالتعرف على حالات جديدة من الرجفان الأذيني التي لم يكن ليتم الانتباه لها سريريًا خلال الرعاية الروتينية.

Released: 21-Nov-2022 3:05 PM EST
Exámenes de detección guiados por inteligencia artificial usan datos de electrocardiogramas para detectar factores de riesgo ocultos de accidente cerebrovascular
Mayo Clinic

os investigadores de Mayo Clinic utilizaron inteligencia artificial para evaluar electrocardiogramas de pacientes en el marco de una estrategia dirigida para detectar fibrilación auricular, un trastorno frecuente del ritmo cardíaco. La fibrilación auricular es un latido cardíaco irregular que puede provocar coágulos sanguíneos que podrían viajar al cerebro y causar un accidente cerebrovascular, y suele ser difícil de diagnosticar.

Released: 21-Nov-2022 2:55 PM EST
A triagem guiada por inteligência artificial usa dados de eletrocardiograma para detectar os fatores de risco ocultos que provocam AVC
Mayo Clinic

Pesquisadores da Mayo Clinic usaram inteligência artificial para avaliar eletrocardiogramas de pacientes em uma estratégia direcionada para examinar a fibrilação atrial, um transtorno de ritmo cardíaco comum. A fibrilação atrial é um batimento cardíaco irregular que pode provocar a formação de coágulos de sangue que podem se mover até o cérebro e causar um AVC, entretanto, ela é altamente subdiagnosticada.

Released: 21-Oct-2022 2:20 PM EDT
Study Suggests Discontinuation of Gender-Affirming Hormones in Those Who Start Treatment as Adolescents Is Rare
Lancet

Study from clinic in The Netherlands suggests 98% (704 out of 720) of adolescents with gender dysphoria who initiated gender-affirming hormone treatment as adolescents continued use at follow-up.

Released: 21-Oct-2022 1:10 PM EDT
Single Stranded Suture Threads Could Prevent Pregnancy Infection Complications, C-Stich Trial Finds
University of Birmingham

Women at risk of pregnancy loss who need a specialist surgical procedure could benefit from a single-stranded suture thread to reduce risk of infection, results from the C-STICH clinical trial found.

Newswise: UT Southwestern Diabetes Expert Recommends Paradigm Shift In Treatment of Type 2 Diabetes to Focus on Weight Loss
Released: 30-Sep-2021 6:05 PM EDT
UT Southwestern Diabetes Expert Recommends Paradigm Shift In Treatment of Type 2 Diabetes to Focus on Weight Loss
UT Southwestern Medical Center

An international panel of experts from four renowned diabetes research centers, including UT Southwestern Medical Center, has reviewed current literature and is recommending a pivotal change in treatment of Type 2 diabetes to focus on obesity first and glucose control second.

Released: 11-Nov-2020 8:00 AM EST
‘Pinprick’ biomarker blood test offers diagnostic potential in HPV-related cancers Study shows rising antibody levels predict the course of cancer
Abviris

A potential breakthrough in the early detection of the neck, head and anal cancers linked to human papilloma viruses (HPV) has emerged. It is based on a highly specific diagnostic test that appears to indicate cancer, and predict its course, from just a pinprick of blood.

14-Feb-2020 9:20 AM EST
World failing to provide children with a healthy life and a climate fit for their future: WHO-UNICEF-Lancet
World Health Organization (WHO)

As climate and commercial threats intensify, WHO-UNICEF-Lancet Commission presses for radical rethink on child health

19-Nov-2019 11:05 AM EST
New WHO-led study says majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk
World Health Organization (WHO)

The first ever global trends for adolescent insufficient physical activity show that urgent action is needed to increase physical activity levels in girls and boys aged 11 to 17 years. The study, published in The Lancet Child & Adolescent Health journal and produced by researchers from the World Health Organization (WHO), finds that more than 80% of school-going adolescents globally did not meet current recommendations of at least one hour of physical activity per day – including 85% of girls and 78% of boys.

Released: 7-Nov-2019 1:05 PM EST
Galactic fountains and carousels: order emerging from chaos
Royal Astronomical Society

Scientists from Germany and the United States have unveiled the results of a newly-completed

8-May-2019 1:00 PM EDT
New Analysis Predicts Top 25 U.S. Counties at Risk for Measles Outbreaks
 Johns Hopkins University

A new analysis co-led by The Johns Hopkins University identified 25 United States counties that are most likely to experience measles outbreaks in 2019. The analysis combined international air travel volume, non-medical exemptions from childhood vaccinations, population data and reported measles outbreak information.

27-Mar-2017 11:30 AM EDT
Man with Quadriplegia Employs Injury Bridging Technologies to Move Again—Just by Thinking
Case Western Reserve University

Bill Kochevar, who was paralyzed below his shoulders in a bicycling accident, is believed to be the first person with quadriplegia in the world to have arm and hand movements restored with the help of two temporarily implanted technologies.

27-Oct-2016 3:30 PM EDT
Optical Coherence Topography Offers Superior Resolution in Coronary Stent Implantation, According to Study
New York-Presbyterian Hospital

Optical coherence tomography (OCT) provides safe and improved guidance for patients undergoing percutaneous coronary intervention to treat coronary artery disease, according to results from the ILLUMIEN III: OPTIMIZE PCI trial.

Released: 27-Sep-2016 9:05 AM EDT
Surprising Findings on Deadly Diarrhea Suggest Ways to Save Children's Lives
University of Virginia Health System

New research offers unprecedented insights into the causes of childhood diarrhea, the second-leading cause of death of children worldwide, and suggests that the role of pathogens has been vastly underestimated.

Released: 23-Sep-2016 12:05 PM EDT
Cities of the Future
Washington University in St. Louis

A new study from Washington University in St. Louis suggests eight interventions that will help create healthier and more sustainable cities of the future, built to reduce the negative impacts of pollution, climate change, noise and crime.

Released: 23-Sep-2016 11:05 AM EDT
Science Can Shape Healthy City Planning
UC San Diego Health

A three-part series published in The Lancet and released in conjunction with the United Nations quantifies health gains achieved if cities were designed so that shops, facilities, work and public transportation were within walking distance of most residents.In part three of the series, researchers tackle how to implement timely research into city design, planning and policy to improve the health of a city’s residents.

   
1-Sep-2016 6:30 PM EDT
Implanted Device Successfully Treats Central Sleep Apnea, Study Finds
Ohio State University Wexner Medical Center

Results from an international, randomized study show that an implanted nerve stimulator significantly improves symptoms in those with central sleep apnea, without causing serious side effects.

Released: 26-Aug-2016 7:05 PM EDT
A Few Extra Pounds Can’t Hurt You — or Can They?
University of Southern California (USC)

Being overweight increases the chances of premature death, said Jonathan Samet of USC. His statement is backed by a four-continent effort involving 239 studies and data from 10.6 million people. The study — one of the largest to date — runs counter to the results of a JAMA, which found that being overweight actually adds to one’s life span.

16-Aug-2016 1:30 PM EDT
UNC Researcher Provides Recommendations to Stop Violence Against Clinicians in China
University of North Carolina Health Care System

With publications in prestigious medical journals and multimillion dollar federal grants, UNC faculty have shown they are committed to moving the fields of HIV prevention, treatment and cure research forward.

Released: 1-Aug-2016 2:05 PM EDT
How to Get This Country Moving
Washington University in St. Louis

Greater efforts should be made to actively monitor physical activity as a risk factor in clinical practice, finds a new study from the Brown School at Washington University in St. Louis.

Released: 28-Jul-2016 9:05 AM EDT
CATCH Identified as Successfully Scaled-Up Physical Activity Intervention
University of Texas Health Science Center at Houston

In a paper published today in a special physical activity series of The Lancet, the Coordinated Approach to Child Health (CATCH) program developed by researchers at The University of Texas Health Science Center at Houston (UTHealth) was identified as an excellent example of an evidence-based physical activity intervention that has been successfully scaled up to affect population health.

Released: 27-Jul-2016 6:05 PM EDT
Increase in Physical Activity Lags Despite Calls to Step it Up During the 2012 Olympics
UC San Diego Health

Ahead of the Summer Olympic Games in London four years ago, researchers reported that physical inactivity was a global pandemic that required urgent action. With the 2016 Games looming, University of California San Diego School of Medicine investigators report little change in activity levels worldwide.

Released: 27-Jul-2016 10:05 AM EDT
'Screen-and-Treat' Scheme for Hepatitis B May Prevent Deadly Complications
Imperial College London

Research into Africa's first 'screen-and-treat' programme for hepatitis B suggests the initiative may reduce deadly complications of the virus.

Released: 25-Jul-2016 9:05 AM EDT
Combining New and Old Drugs Improves Survival for Soft-Tissue Cancer Patients
Columbia University Irving Medical Center

Adding a novel monoclonal antibody therapy called olaratumab to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, according to a multicenter clinical trial led by researchers at Columbia University Medical Center and NewYork-Presbyterian.

22-Jul-2016 11:05 AM EDT
Personalized Medicine Meets Thyroid Cancer: Drug Targeting BRAF Mutation Helps Patients
Perelman School of Medicine at the University of Pennsylvania

Researchers from Penn Medicine and other institutions found that treating metastatic thyroid cancer patients harboring a BRAF mutation with the targeted therapy vemurafenib —originally approved for melanoma patients with the mutation—showed promising anti-tumor activity in a third of patients. The results were published in this week’s Lancet Oncology.

Released: 18-Jul-2016 1:05 PM EDT
Rise in Avoidable Diabetes Hospital Visits
University of Leicester

Hospital admissions for a short-term and avoidable complication of diabetes have risen by 39 per cent in the last ten years, a new analysis has concluded.

Released: 13-Jul-2016 10:05 AM EDT
HPV Vaccine Can Protect Women Across a Broad Age Range
University of New Mexico Comprehensive Cancer Center

A research paper published in The Lancet Infectious Diseases reported that the human papillomavirus (HPV) vaccine is safe and efficacious across a wide age range of women. The international study found that it protects against HPV infection in women older than 26 years.

Released: 10-Jul-2016 4:05 PM EDT
Viral Hepatitis is the Seventh Leading Cause of Death Worldwide; U.S. Treatment Interventions Continue To Go Underfunded
O'Neill Institute for National & Global Health Law

An article published on July 6, 2016 in The Lancet ranks viral hepatitis infections – specifically both Hepatitis B (HBV) and Hepatitis C (HCV) – as the seventh leading cause of death worldwide in 2013, up from tenth in 1990. …hepatitis C is a critical public health concern that, despite the consistent release of research stating its increasing adverse impact on public health, continues to see woeful underfunding for prevention and treatment initiatives to curtail its spread.

5-Jul-2016 11:30 AM EDT
Despite Advances, HIV Epidemic Continues Among Gay Men Across the Globe
Johns Hopkins Bloomberg School of Public Health

Gay, bisexual and other men who have sex with men continue to have disproportionately high burdens of HIV infection in countries of low, middle and high income around the world, a new study led by the Johns Hopkins Bloomberg School of Public Health suggests.

Released: 15-Jun-2016 1:05 PM EDT
Piping Hot Drinks May Lead to Cancer of the Esophagus
University of Southern California (USC)

Drinking piping hot coffee, tea and the caffeine-infused beverage yerba mate probably causes cancer, the World Health Organization announced Wednesday.

Released: 13-Jun-2016 6:30 PM EDT
Endocrine Society Experts Urge EU to Protect Public from Chemical Exposure
Endocrine Society

To protect human health, Endocrine Society members called on the European Commission to adopt science-based policies for regulating endocrine-disrupting chemicals in an opinion piece published today in The Lancet Diabetes & Endocrinology.

9-Jun-2016 6:30 PM EDT
‘Invisible Wounds of War’ Now Visible
Uniformed Services University of the Health Sciences (USU)

Scientists have discovered a unique pattern of scarring in the brains of deceased service members who were exposed to blast injury that differs from those exposed to other types of head injury. This new research was published online June 9 in Lancet Neurology, “Characterisation of Interface Astroglial Scarring in the Human Brain after Blast Exposure: a Post-mortem Case Series.”

20-May-2016 6:30 PM EDT
Low Salt Diets Not Beneficial: Global Study Finds
McMaster University

A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption.

Released: 17-May-2016 5:00 PM EDT
Care for COPD: Could More Be Done?
Michigan Medicine - University of Michigan

Meilan Han, M.D., an associate professor of internal medicine at the University of Michigan and the medical director of the U-M Women’s Respiratory Health Program, is the lead author on a new report that set out to provide a comprehensive view of COPD care in the U.S.


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