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Newswise: First Study to Directly Compare Gene Mutation Type in Individuals With CHAMP1 Disorder Indicates Key Differences
Released: 17-Jul-2023 2:25 PM EDT
First Study to Directly Compare Gene Mutation Type in Individuals With CHAMP1 Disorder Indicates Key Differences
Mount Sinai Health System

Understanding the causes of this neurodevelopmental disorder is important to the development of new precision medicine therapies.

Newswise:Video Embedded cytovale-reveals-10-minute-510-k-pending-cytovale-system-and-intellisep-test-for-sepsis-at-aacc-2022
Released: 25-Jul-2022 10:40 AM EDT
Cytovale Reveals 10-Minute, 510(K) Pending Cytovale System and Intellisep Test for Sepsis at AACC 2022
2022 AACC Annual Scientific Meeting Press Program

Cytovale®, a medical diagnostics company focused on providing rapid and insightful tools to improve early detection of fast-moving and immune-mediated diseases, will reveal its 510(k) pending Cytovale system and 10-minute IntelliSep® sepsis risk stratification test at the American Association for Clinical Chemistry (AACC) annual meeting, where new data featuring the test will also be shared. The instrument can be seen in the Cytovale booth, no. 5045, in the exhibit hall during Clinical Lab Expo hours. The IntelliSep test was recently named an AACC Disruptive Technology Award Semifinalist and is also being featured in the Disruptive Tech area of the exhibit hall during the meeting.

Released: 15-Jun-2020 6:00 AM EDT
5 Key Areas of Cancer Research Presented by Thought Leaders at Annual Review in Oncology Virtual Symposium
Atlantic Health System

Atlantic Health System Cancer Care will continue its tradition of world-class medical education with its 2020 Annual Review in Oncology Virtual Symposium. The symposium, held virtually this year with free registration, will take place Saturday, June 27, 2020, from 8 a.m. to 12:30 p.m. ET. Distinguished faculty from some of the Northeast’s leading cancer centers will summarize the latest advances in oncology, which have recently been presented at international conferences. The diverse range of topics should be of interest to surgeons, medical and radiation oncologists and other physicians, nurses and allied health professionals.

10-Jun-2020 5:05 PM EDT
LJI scientists uncover immune cells that may lower airway allergy and asthma risk
La Jolla Institute for Immunology

In a new Science Immunology study, published on June 12, 2020, scientists at La Jolla Institute for Immunology (LJI) offer a clue to why non-allergic people don’t have a strong reaction to house dust mites. They’ve uncovered a previously unknown subset of T cells that may control allergic immune reactions and asthma from ever developing in response to house dust mites—and other possible allergens.

8-May-2019 1:00 PM EDT
New Analysis Predicts Top 25 U.S. Counties at Risk for Measles Outbreaks
 Johns Hopkins University

A new analysis co-led by The Johns Hopkins University identified 25 United States counties that are most likely to experience measles outbreaks in 2019. The analysis combined international air travel volume, non-medical exemptions from childhood vaccinations, population data and reported measles outbreak information.

29-Apr-2019 9:00 AM EDT
Mouse Studies Show Minimally Invasive Route Can Accurately Administer Drugs to Brain
Johns Hopkins Medicine

In experiments in mice, Johns Hopkins researchers say they have developed a technique that facilitates the precise placement of cancer drugs at their intended targets in the brain. This approach pairs a technique that guides a catheter through the brain’s arteries with positron emission technology (PET) scans to precisely place cancer drugs at their intended targets in the brain. If future studies show this image-guided drug delivery method is safe and effective in humans, the researchers say it could improve outcomes for historically difficult-to-treat and often lethal brain cancers, such as glioblastoma.

23-Jan-2019 3:30 PM EST
Study: Lower-Carbon Diets Aren’t Just Good for the Planet, They’re Also Healthier
Tulane University

Researchers examined the daily diets of more than 16,000 people to compare the climate impact and nutritional value of what America eats in a day. They found that diets that were more climate-friendly were also healthier.

Released: 29-Oct-2018 10:05 AM EDT
Researchers Ground-Breaking Discovery Finds New Link Between Autoimmune Diseases and a Gut Bacterium
Queen's University Belfast

Could microbes in our guts be sending out the wrong message? Queen’s University researchers have, for the first time, found a specific microbe in the gut that pumps out protein molecules that mimic a human protein, causing the human defence system to turn on its own cells by mistake.

Released: 6-Sep-2018 3:50 PM EDT
‘Mindful People’ Feel Less Pain; MRI Imaging Pinpoints Supporting Brain Activity
Atrium Health Wake Forest Baptist

Ever wonder why some people seem to feel less pain than others? A study conducted at Wake Forest School of Medicine may have found one of the answers – mindfulness.

Released: 20-Aug-2018 9:00 AM EDT
In Teen Friendships, Misery Does Love Company
Florida Atlantic University

A study examined anxiety, depression, social withdrawal, and submissiveness to predict the end of teen friendships. Do friendships end because of one child’s mental health problems or do they end because of differences between friends on the degree to which each friend suffers from these problems? A key finding shows that children’s personal struggles need not adversely impact their social relationships, and mental health issues do not necessarily ruin their chances of making and maintaining worthwhile friendships.

17-Jul-2018 10:00 AM EDT
‘Good Cholesterol’ May Not Always be Good for Postmenopausal Women
Health Sciences at the University of Pittsburgh

Postmenopausal factors may have an impact on the heart-protective qualities of high-density lipoproteins (HDL) – also known as ‘good cholesterol.’ The findings bring into question the current use of total HDL cholesterol to predict heart disease risk.

Released: 17-Jul-2018 8:05 AM EDT
Researchers Show Impact of Outdoor Behavioral Healthcare More Lasting
University of New Hampshire

Mental health and substance abuse issues in adolescents have become major societal problems, forcing parents and health providers to look for innovative treatment options that may better suit some teens. However, some proven therapy programs, like Outdoor Behavioral Healthcare (OBH), can be challenging to access because many are not covered by insurance companies – creating an enormous cost burden for parents. Now, a landmark study by researchers at the University of New Hampshire has found that parents of youth who went through an outdoor behavioral program report that their children showed almost three times the improvement after one year than youth who remained in their communities for more traditional treatment.

28-Jun-2018 9:00 AM EDT
Air Pollution Contributes Significantly to Diabetes Globally
Washington University in St. Louis

New research links outdoor air pollution — even at levels deemed safe — to an increased risk of diabetes globally, according to a study from Washington University School of Medicine in St. Louis and the Veterans Affairs (VA) St. Louis Health Care System. The findings raise the possibility that reducing pollution may lead to a drop in diabetes cases in heavily polluted countries such as India and less polluted ones such as the United States.

27-Jun-2018 11:00 AM EDT
Don’t Let Depression Keep You From Exercising
UT Southwestern Medical Center

Exercise may be just as crucial to a depression patient’s good health as finding an effective antidepressant.

31-May-2018 1:05 PM EDT
Landmark Study Finds More Breast Cancer Patients Can Safely Forgo Chemotherapy
Loyola Medicine

A 21-gene test could enable most patients with the most common type of early breast cancer to safely forgo chemotherapy, according to a landmark study published in the New England Journal of Medicine. Loyola Medicine oncologist Kathy Albain, MD, is among the main co-authors.

29-May-2018 8:00 AM EDT
Brain Scientists Identify ‘Cross Talk’ Between Neurons That Control Touch in Mice
Johns Hopkins Medicine

Scientists report they have uncovered a previously overlooked connection between neurons in two distinct areas of the mammalian brain. The neurons, they say, control the sense of touch, and their experiments in mice offer insights into mapping brain circuitry that is responsible for normal and abnormal perception and movements linked to touch.

14-May-2018 4:50 PM EDT
International Study Suggests Alternative Treatment for Mild Asthma
McMaster University

People with mild asthma are often prescribed a daily treatment regimen, but up to 80 per cent do not follow the routine, using inhalers only when they have an asthma attack. Now the researchers have found an as-needed combined-drug inhaler is a viable treatment option.

11-May-2018 10:00 AM EDT
The Opioid Epidemic Has Boosted the Number of Organs Available for Transplant
University of Utah Health

The researchers examined 17 years of transplantation records and found no significant change in the recipients’ chance of survival when the organ donation came from victims of drug intoxication. The study publishes online on May 17 in the New England Journal of Medicine.

Released: 14-May-2018 10:00 AM EDT
Tip Sheet: Johns Hopkins Researchers Present Study Findings at Society for Academic Emergency Medicine Meeting 2018
Johns Hopkins Medicine

The annual meeting of the Society for Academic Emergency Medicine (SAEM). The SAEM 2018 meeting will bring together more than 3,000 physicians, researchers, residents and medical students from around the world.

Released: 14-May-2018 8:05 AM EDT
New Method Could Improve Longevity and Lessen Wear of Artificial Hips
University of Arkansas, Fayetteville

Mechanical engineering researchers have developed a method that could extend the life of an artificial hip by adding an array of microscopic indentations that increase the thickness of a lubricating film on its surface.

Released: 7-May-2018 3:40 PM EDT
Simple Treatment May Minimize Hearing Loss Triggered by Loud Noises
Keck Medicine of USC

New research from the Keck School of Medicine of USC reveals how traumatic noise damages hearing and identifies a potential way to preserve it

Released: 3-May-2018 4:35 PM EDT
Increased Nerve Activity Raises Blood Pressure, Risk of Heart Disease in People with Chronic Anxiety
American Physiological Society (APS)

Sympathetic nerve activity to skeletal muscle blood vessels—a function of the nervous system that helps regulate blood pressure—increases during physiological and mental stress in people with chronic anxiety, a new study finds.

27-Apr-2018 10:00 AM EDT
Sex After 65: Poll of Older Adults Finds Links to Health, Gender Differences, Lack of Communication with Doctors
Michigan Medicine - University of Michigan

A new poll busts stereotypes about the sex lives of older Americans – and reveals gender and health-related divides on key aspects of sexual health, while highlighting the need for more people to talk with their health providers about sexual issues.

27-Apr-2018 12:05 PM EDT
Bacteria’s Appetite May Be Key to Cleaning Up Antibiotic Contamination
Washington University in St. Louis

Some bacteria not only escape being killed by bacteria, they turn it into food. Until now, scientists have understood little about how bacteria manage to consume antibiotics safely, but new research from Washington University School of Medicine in St. Louis illuminates key steps in the process. The findings, published April 30 in Nature Chemical Biology, could lead to new ways to eliminate antibiotics from land and water, the researchers said. Environmental antibiotic contamination promotes drug resistance and undermines our ability to treat bacterial infections.

Released: 20-Apr-2018 10:05 AM EDT
Meditation Could Help Anxiety and Cardiovascular Health
Michigan Technological University

In a student-led study, one hour of mindfulness meditation shown to reduce anxiety and some cardiovascular risk markers.

Released: 16-Apr-2018 8:00 AM EDT
Evidence Mounts that Daily Opioid Users May Fare Worse After Spine Surgery, Study Finds
Johns Hopkins Medicine

In a multicenter database study of adults who had undergone surgery for spinal deformities, researchers say that those who had used narcotics daily on average had worse outcomes, such as longer intensive care unit stays and more severe postop disability, compared with those who did not use opioids preoperatively.

11-Apr-2018 4:15 PM EDT
How Highly Contagious Norovirus Infection Gets Its Start
Washington University in St. Louis

Researchers have shown, in mice, that norovirus infects a rare type of intestinal cell called a tuft cell. Inside tuft cells, norovirus is effectively hidden from the immune system, which could explain why some people continue to shed virus long after they are no longer sick. These “healthy carriers” are thought to be the source of norovirus outbreaks, so understanding how the virus evades detection in such people could lead to better ways to prevent outbreaks.

11-Apr-2018 3:25 PM EDT
Sitting Is Bad for Your Brain – Not Just Your Metabolism or Heart
University of California, Los Angeles (UCLA), Health Sciences

Sitting, like smoking, increases the risk of heart disease, diabetes and premature death. Researchers at UCLA wanted to see how sedentary behavior influences brain health, especially regions of the brain that are critical to memory formation.

20-Mar-2018 1:00 PM EDT
Whether Sustained or Sporadic, Exercise Offers Same Reductions in Death Risk
Duke Health

New data shows that all moderate or vigorous exercise can add up to reduce the risk of disease or death, even if you are exercising only in short bursts throughout the day.

Released: 6-Mar-2018 5:05 AM EST
Bright Nighttime Light Kills Melatonin Production in Preschoolers
University of Colorado Boulder

A new CU Boulder study shows that one hour of bright light at night nearly eliminates melatonin production in young children and keeps it suppressed an hour after light's out. Structural differences may make children's immature eyes more vulnerable to body clock disruption from light.

26-Feb-2018 9:00 AM EST
Records Study Suggests Gender Affirming Surgeries On The Rise Along with Insurance Coverage
Johns Hopkins Medicine

In a national medical records analysis, researchers at Johns Hopkins Medicine say there is evidence that the number of gender affirming surgeries performed in hospitals for transgender individuals is on the rise, along with increased access made possible by Medicare, Medicaid or private insurance coverage for the procedures.

Released: 22-Feb-2018 8:05 AM EST
Cardiac Magnetic Resonance Without Intravenous Contrast May Help Better Assess Need for Mitral Valve Surgery
Atlantic Health System

Atlantic health system cardiologist authors new review on value of non-invasive imaging techniques in valvular heart disease patients

19-Feb-2018 11:30 AM EST
New Therapeutic Gel Shows Promise Against Cancerous Tumors
University of North Carolina Health Care System

UNC and NC State scientists created an injectable gel-like scaffold that can hold combination chemo-immunotherapeutic drugs and deliver them locally to tumors in a sequential manner. The results in animal models suggest this approach could one day ramp up therapeutic benefits for cancer patients.

16-Feb-2018 11:00 AM EST
African Americans with Atrial Fibrillation at Significantly Higher Risk for Stroke Compared to Caucasians with the Disease
Perelman School of Medicine at the University of Pennsylvania

African Americans with atrial fibrillation (AF) – a quivering or irregular heartbeat that can lead to a host of dangerous complications – have a significantly higher risk of stroke than Caucasians with the condition, according to new research published today in HeartRhythm by researchers from the Perelman School of Medicine at the University of Pennsylvania. The new findings build on previous studies examining the impact of race on the risk of developing atrial fibrillation (AF), which is linked to blood clots, stroke, heart failure and other complications. It’s well reported that African Americans have a lower risk of developing AF as compared to Caucasians, but until now, there was little data on the additional risks that come with AF for each race.

7-Feb-2018 8:05 AM EST
Researchers Successfully Reverse Alzheimer’s Disease in Mouse Model
The Rockefeller University Press

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, thereby improving the animals’ cognitive function. The study, which will be published February 14 in the Journal of Experimental Medicine, raises hopes that drugs targeting this enzyme will be able to successfully treat Alzheimer’s disease in humans.

Released: 13-Feb-2018 4:50 PM EST
Newly Discovered Gene May Protect Against Heart Disease
University of California, Los Angeles (UCLA), Health Sciences

Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels.

6-Feb-2018 1:05 AM EST
Diet May Influence the Spread of a Deadly Type of Breast Cancer, Study Finds

A single protein building block commonly found in food may hold a key to preventing the spread of an often-deadly type of breast cancer, according to a new multicenter study published today in the medical journal Nature. Investigators found that by limiting an amino acid called asparagine in laboratory mice with triple-negative breast cancer, they could dramatically reduce the ability of the cancer to travel to distant sites in the body. Among other techniques, the team used dietary restrictions to limit asparagine.

Released: 1-Feb-2018 3:40 PM EST
Pre-Clinical Research Aided by Customized Collection Capabilities

Conversant Bio™ has partnered with Streck to provide cancer researchers with customized clinical plasma samples that are research-ready, allowing researchers to focus on their studies and not their sample collection processing and logistics.

29-Jan-2018 12:05 PM EST
Like Zika, West Nile Virus Causes Fetal Brain Damage, Death in Mice
Washington University in St. Louis

Two viruses closely related to Zika – West Nile and Powassan – can spread from an infected pregnant mouse to her fetuses, causing brain damage and fetal death, according to a new study from Washington University School of Medicine in St. Louis. The findings suggest that Zika may not be unique in its ability to cause miscarriages and birth defects.

Released: 31-Jan-2018 12:05 PM EST
ID’ing Features of Flu Virus Genome May Help Target Surveillance for Pandemic Flu
Washington University in St. Louis

A pandemic flu outbreak could kill millions. Now, researchers have found features of the virus's genome that influence how well it multiplies. The findings could help target pandemic flu surveillance efforts to make it easier to find the next outbreak before it spreads widely.

26-Jan-2018 4:30 PM EST
Body Clock Disruptions Occur Years Before Memory Loss in Alzheimer’s
Washington University in St. Louis

People with Alzheimer’s disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers at Washington University School of Medicine in St. Louis have found that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer’s.

Released: 26-Jan-2018 10:35 AM EST
Research Suggests Colonoscopy Link to Appendicitis
University of North Dakota

Although the incidence of appendicitis in the United States has been in decline for many years, the condition still affects approximately seven percent of Americans annually.

22-Jan-2018 2:45 PM EST
Scientific Breakthrough Could Lead to Better Antipsychotic Drugs
University of North Carolina Health Care System

Published in Nature, research from the UNC School of Medicine and UCSF revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects.

15-Jan-2018 9:00 AM EST
Previous Influenza Virus Exposures Enhance Susceptibility in Another Influenza Pandemic
McMaster University

New data analysis suggests that people born at the time of the 1957 H2N2 or Asian Flu pandemic were at a higher risk of dying during the 2009 H1N1 Swine Flu pandemic as well as the resurgent H1N1 outbreak in 2013-2014. And it is not the first time this has happened.

8-Jan-2018 4:35 PM EST
New Stem Cell Method Sheds Light on a Telltale Sign of Heart Disease
University of Wisconsin–Madison

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

4-Jan-2018 12:45 PM EST
Proper Exercise Can Reverse Damage From Heart Aging
UT Southwestern Medical Center

Exercise can reverse damage to sedentary, aging hearts and help prevent risk of future heart failure – if it’s enough exercise, and if it’s begun in time, according to a new study by cardiologists at UT Southwestern and Texas Health Resources.

Released: 5-Jan-2018 12:05 AM EST
In Scientific First, Researchers Grow Hairy Skin In A Dish
Indiana University

Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells—a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers.