Press "esc" to clear
Go to Advanced Search

Showing results

110 of 78
RedAxonsSARM1Geisler.jpg

Article ID: 706667

Gene therapy blocks peripheral nerve damage in mice

Washington University in St. Louis

Scientists at Washington University School of Medicine in St. Louis have developed a gene therapy that blocks axonal degeneration, preventing axon destruction in mice and suggesting a therapeutic strategy that could help prevent the loss of peripheral nerves in multiple conditions.

Released:
17-Jan-2019 12:05 PM EST
Lazicetal.jpg
  • Embargo expired:
    15-Jan-2019 9:00 AM EST

Article ID: 706121

Stroke drug may also prevent Alzheimer’s disease, say USC researchers

The Rockefeller University Press

Researchers from the University of Southern California have discovered that a drug currently being developed to treat stroke patients could also prevent Alzheimer’s disease. The study, which will be published January 15 in the Journal of Experimental Medicine, shows that the genetically engineered protein 3K3A-APC protects the brains of mice with Alzheimer’s-like symptoms, reducing the buildup of toxic peptides and preventing memory loss.

Released:
8-Jan-2019 9:45 AM EST
Lee et al_1.jpg
  • Embargo expired:
    19-Dec-2018 9:00 AM EST

Article ID: 705309

DNA “Webs” Aid Ovarian Cancer Metastasis, Study Reveals

The Rockefeller University Press

Researchers from the University of Texas MD Anderson Cancer Center have discovered that ovarian cancer cells spread, or metastasize, to new tissue after being caught in DNA "webs" extruded by immune cells. The study, which will be published December 19 in the Journal of Experimental Medicine, reveals that preventing immune cells from forming these webs reduces metastasis in mice, suggesting that similar treatments could be used to limit the spread of ovarian cancer in humans.

Released:
12-Dec-2018 10:05 AM EST
JeffSchoreyTB.JPG

Article ID: 704971

Tuberculosis survives by using host system against itself

University of Notre Dame

In a new study published in the Journal of Experimental Medicine, scientists at the University of Notre Dame have discovered that the pathogen Mycobacterium tuberculosis (MTB) releases RNA into infected cells.

Released:
5-Dec-2018 12:05 PM EST
Razetal.jpg
  • Embargo expired:
    23-Nov-2018 9:00 AM EST

Article ID: 704067

Breast Cancers Enhance Their Growth by Recruiting Cells From Bone Marrow

The Rockefeller University Press

Researchers in Israel have discovered that breast tumors can boost their growth by recruiting stromal cells originally formed in the bone marrow. The study, which will be published November 23 in the Journal of Experimental Medicine, reveals that the recruitment of bone marrow–derived fibroblasts lowers the odds of surviving breast cancer, but suggests that targeting these cells could be an effective way of treating the disease.

Released:
15-Nov-2018 10:05 AM EST
Cardinezetal.jpg
  • Embargo expired:
    18-Oct-2018 9:00 AM EDT

Article ID: 702172

Researchers Describe Novel Immune Syndrome

The Rockefeller University Press

Researchers from Australia and Japan have discovered a new human immunodeficiency syndrome in two patients on separate continents. The study, which will be published October 18 in the Journal of Experimental Medicine, reveals that a mutation in a gene called IKBKB disrupts the immune system, leading to excessive inflammation and the loss of both T and B white blood cells.

Released:
15-Oct-2018 9:45 AM EDT
Wongetal2018.large.jpg

Article ID: 701162

T Cells in the Urine of Bladder Cancer Patients Reflect Tumor Environment

The Rockefeller University Press

Scientists in the UK have shown for the first time that immune cells in the urine of bladder cancer patients accurately reflect those in the tumor environment, according to the study “Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment,” by Wong et al., published today in the Journal of Experimental Medicine.

Released:
26-Sep-2018 12:05 PM EDT
Nestoretal.jpg
  • Embargo expired:
    5-Sep-2018 9:00 AM EDT

Article ID: 699905

Hypertension Drugs Could Prevent Memory Loss in Lupus Patients, Study Suggests

The Rockefeller University Press

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus (SLE). The study, which will be published September 5 in the Journal of Experimental Medicine, shows that ACE inhibitors—a class of drugs commonly used to treat hypertension—can block this process in mice and might therefore be used to preserve the memory of lupus patients.

Released:
4-Sep-2018 8:05 AM EDT
Chakrabartyetal.jpg
  • Embargo expired:
    29-Aug-2018 9:00 AM EDT

Article ID: 699337

Researchers Identify New Potential Biotherapy for Alzheimer’s Disease

The Rockefeller University Press

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer’s disease. The study, which will be published August 29 in the Journal of Experimental Medicine, reveals that soluble versions of a protein called TLR5 can reduce the buildup of amyloid plaques in the brains of Alzheimer’s disease model mice and prevent the toxic peptide that forms these plaques from killing neurons.

Released:
22-Aug-2018 9:50 AM EDT
caron_cell_2018.jpg
  • Embargo expired:
    16-Aug-2018 9:00 AM EDT

Article ID: 699041

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs

University of North Carolina Health Care System

Researchers discovered a gene mutation underlying hydrops fetalis – a fatal condition to fetuses. The proteins at the center of this finding are implicated in a number of diseases, opening avenues of potential drug discovery related to migraines, diabetes, osteoporosis, and other conditions.

Released:
15-Aug-2018 1:05 PM EDT

Showing results

110 of 78

Chat now!