Johns Hopkins researchers have discovered that use of the synthetic psychedelic 5-methocy-N,-N-dimethyltryptamine (5-MeO-DMT) appears to be associated with unintended improvements in self-reported depression and anxiety when given in a ceremonial group setting. 5-MeO-DMT is a psychedelic that is found in the venom of Bufo Alvarius toads, in a variety of plants species, and can be produced synthetically.
Findings could fundamentally change how scientists interpret the biological activities of serotonin
Faced with the surge in “diseases of despair,” policymakers and leaders in the health care sector are beginning to see the limitations of the current highly centralized, medicalized system of providing health care. A new report commissioned by the Robert Wood Johnson Foundation says the nursing profession has a historic opportunity to address this public health crisis of the 21st century.
Most heroin users in Baltimore, a city heavily affected by the opioid epidemic, recognize that the heroin they buy is now almost always laced with the highly dangerous synthetic opioid fentanyl, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Young adults at risk of developing problems with addiction show key differences in an important region of the brain, according to an international team led by researchers at the University of Cambridge.
Researchers at UC San Diego School of Medicine have identified a clear group of characteristics that predict heightened risk for experiencing increased anxiety or worsening of mood that interferes with daily activities when using a smoking cessation drug. Results are published in the February 27 online edition of the Journal of General Internal Medicine.
Assessment of Changes in the Geographical Distribution of Opioid-Related Mortality Across the United States by Opioid Type, 1999-2016
A study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that the Food and Drug Administration (FDA) and manufacturers did not take action when evidence emerged that potentially lethal fentanyl products were being inappropriately prescribed to patients.
University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.
The opioid epidemic could be responsible for 700,000 overdose deaths in the United States between 2016 and 2025, according to a new study published today in JAMA Network Open.
Nearly 1 percent of high school seniors report using Flakka, a highly potent and potentially dangerous synthetic drug, according to a study by researchers at NYU School of Medicine, the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU College of Global Public Health, and Columbia University Mailman School of Public Health.
Researchers identified the brain circuits that form memories associating environmental cues with cocaine use and used optogenetics to specifically target those memories and reduce relapse-like behavior.
A study finds a surprising response to cocaine in a novel strain of mutant mice – they failed to show hyperactivity seen in normal mice when given cocaine and didn’t run around. In other tests, they still found cocaine appealing, but displayed an inability to shake the memory of cocaine’s actions when the drug was no longer administered. The key change that blocks cocaine’s stimulant effects in these mice is serotonin, not dopamine, which is responsible for producing a high.
Despite the mounting death toll of America’s opioid crisis, only a minority of facilities that treat substance use disorders offer patients buprenorphine, naltrexone or methadone—the three FDA-approved medications for the long-term management of opioid use disorder, according to a new study from researchers at the Johns Hopkins Bloomberg School of Public Health.
Researchers know that lesbian, gay and bisexual individuals are more likely than heterosexuals to use alcohol, tobacco or other drugs, but until now they didn't know to what degree.
Pain and substance use interact in a vicious cycle that can ultimately worsen and maintain both chronic pain and addiction, according to a research team including faculty at Binghamton University, State University of New York.
UW researchers have developed a smartphone app that uses sonar to monitor someone's breathing rate and sense when an opioid overdose has occurred.
Embargoed research covered by CBS News
States do not regulate the potency of recreational cannabis, even though THC levels have increased significantly. Now new research shows higher average potency cannabis at first use increases the risk for the first symptom of cannabis use disorder.
When improved antidepressants hit the market in the 1980s, heavy drinking among people with depression dropped 22 percent, suggesting people who knowingly use drugs and alcohol to relieve mental and physical pain will switch to safer, better treatment options when they can get them,
A homeless individual is one who lacks fixed and reliable housing, and it is estimated that 553,000 people fit that description on any given night in the United States. A new retrospective cohort study by investigators from Brigham and Women's Hospital and Beth Israel Deaconess Medical Center examines patterns, causes and outcomes of acute hospitalizations between 2007 and 2013 for homeless individuals and non-homeless control groups in three populous and diverse U.S. states: Florida, California and Massachusetts. Data suggest a rise in acute hospital use among homeless individuals for mental illness and substance use disorder. The results were published in the journal Medical Care on Dec. 11.
While friends or family members may feel helpless if someone they know suffers from addiction, one UAB physician says hope can start at home.
Providing supervised access to medical-grade heroin to people whose use continues after trying multiple traditional treatments has been successful in other countries, and should be piloted and studied in the United States, according to a new RAND Corporation study.
New study shows low use of telehealth services for substance use disorder. More than 20 million Americans have substance use disorders related to alcohol, opioids and other drugs. Less than one in five receive treatment for substance use disorder, in part because of lack of providers, especially in rural areas. Telehealth—which allows clinicians to evaluate and treat patients via video conferencing—could help fill this unmet need, but increasing use must overcome regulatory barriers and target rural areas.
As roadway safety remains a pressing public health concern in California, researchers at the Qualcomm Institute and the University of California San Diego School of Medicine have received funding to expand a statewide program known as Training, Research, and Education for Driving Safety (TREDS). TREDS recently launched a public awareness campaign called “Higher Education: Driving High is DUI” to raise awareness about the dangers of driving under the influence of drugs.
A study, which evaluated the prevalence and clinical consequences of prescription amphetamine (AMP) misuse among adolescents and adults, found severe medical outcomes occur when people snort or inject stimulant medication.
Researchers in the Arizona State University Department of Psychology have found the quality of the parent-child relationship steadily declined starting in grade 6, and levels of alienation, trust and communication in middle school predicted depressive symptoms and anxiety in grade 12.
While nearly all Americans say they would choose an alternative to opioid pain relievers following surgery, few patients are talking to their health care provider about it, according to the Mayo Clinic National Health Checkup.
A treatment protocol that sends people home after colorectal operations without any opioids to manage their pain leads to shorter hospital stays.
A new study shows wide variation in prescriptions of sedative drugs, called benzodiazepines, to people with Medicare coverage. Some counties, especially in southern and rural western states, had three times the level of sedative prescribing as others. The study also highlights gaps at the level of individual prescribers: Some primary care providers prescribed sedatives more than six times more often than their peers.
Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago are coming together with the Drug Enforcement Administration to host collection sites for National Prescription Drug Take Back Day on Saturday, October 27.
University of Virginia Health System is partnering with more than 20 other health systems in the AVIA network’s Medicaid Transformation Project to develop financially sustainable solutions to improving the health of the nearly 75 million Americans who receive Medicaid.
Dr. Chinazo Cunningham, M.D., M.S., a New York City-based expert in opioid use disorder will serve on a national board advising the CDC on best approaches to address the nation's opioid epidemic.
A small study shows that business managers and staff—such as those running coffee shops and fast-food restaurants—can be trained to reverse opioid overdoses, which are known to occur in public bathrooms.
Death rates from drug overdoses in the U.S. have been on an exponential growth curve that began at least 15 years before the mid-1990s surge in opioid prescribing, suggesting that overdose death rates may continue along this same historical growth trajectory for years to come.
The medical community has long known that patients on long-term opioid therapy often have significantly more health care visits. But adhering to a standardized care process model for opioid prescriptions appears to reduce the overall number of health care visits for these patients while maintaining safety, shows new research published in Mayo Clinic Proceedings.
Over the long term, being a bystander of high-school violence can be as damaging to mental health as being directly bullied, a new study finds.
A study by researchers at Rutgers Brain Health Institute identifies a promising avenue for treating addiction and clues to why people in recovery relapse
Among older Americans, the poorest are the most likely to have used prescription opioids, according to a University at Buffalo study providing new insights into unexplored contours of the opioid crisis. The study also raises important questions about access to pain management options for the disadvantaged in the current climate of the opioid epidemic.
Nearly 30 percent of outpatient opioid prescriptions in the United States lack documented clinical reasons to justify dispensing the drugs.
Addictions nursing specialists have a unique role to play in caring for patients, families, and communities affected by the crisis. A series of original research and expert commentaries provide the nursing specialist's perspective on the opioid crisis, appearing in the July/September special issue of Journal of Addictions Nursing (JAN), the official journal of the International Nurses Society on Addictions (IntNSA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Single-step nasal spray naloxone is the easiest to deliver, according to new research led by faculty at Binghamton University, State University at New York.
Young adults who report mistreatment (‘maltreatment’ by the authors) during childhood often demonstrate poor decision-making skills and are at risk for developing alcohol or other drug (AOD) problems, in particular when around peers. Research suggests that decision-making depends on a person’s ability to regulate him/herself during socially stressful situations. This study examined relationships between child mistreatment and AOD problems, with a focus on lack of self-regulation by the young adults as a key risk factor.
To better understand how much marijuana or constituent compounds actually get into breast milk and how long it remains, researchers at University of California San Diego School of Medicine conducted a study, publishing online August 27 in Pediatrics.
Christiana Care has reduced opioids prescriptions by 40 percent after some ob-gyn and general surgery procedures, by almost 50 percent for patients discharged from the emergency department and by 37 percent for primary care patients.
Nicole O’Donnell says her first love was benzodiazepines. Now, 2 overdoses and nearly a decade of sobriety later, the mother of two is working towards a bachelor's degree in Psychology and is using her personal journey to make a difference in the lives of those struggling with addiction.
At a time when drug overdoses are becoming more prevalent and lethal, a new report provides a snapshot of regional illicit drug use and, for the first time, highlights the complexity of detecting and treating patients at hospital emergency departments for a severe drug-related event.
A new opioid misuse prevention program called ONE Rx was announced by pharmacy and health care partners in North Dakota. This continuing education program for pharmacists at community pharmacies moves opioid misuse and overdose prevention to the initial patient encounter, increasing awareness when patients first fill an opioid prescription.
Two WVU researchers are studying how Suboxone and Subutex affect babies over the longterm when those medications are used by pregnant mothers.
ROCHESTER, Minn. – Despite increased attention to opioid abuse, prescriptions have remained relatively unchanged for many U.S. patients, research led by Mayo Clinic finds. The research, published in The BMJ, shows that opioid prescription rates have remained flat for commercially insured patients over the past decade. Rates for some Medicare patients are leveling but remain above where they were 10 years ago.
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