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Newswise: Reducing Alzheimer’s-Related Protein in Young Brains Improves Learning
in Down syndrome animal model
  • Embargo expired:
    3-Jun-2010 5:00 PM EDT

Article ID: 565190

Reducing Alzheimer’s-Related Protein in Young Brains Improves Learning in Down syndrome animal model

UT Southwestern Medical Center

Reducing a protein called beta-amyloid in young mice with a condition resembling Down syndrome improves their ability to learn, researchers at UT Southwestern Medical Center have found.

2-Jun-2010 9:00 AM EDT

Article ID: 565026

Deep-Brain Stimulation: Calms PD Shakes—What About the Mind?


A surgical treatment that stimulates distressed neural networks through electrodes threaded directly into a person's brain has quietly made a difference in the lives of tens of thousands of people with Parkinson disease, essential tremor, and dystonia over the course of the past decade. What about the mind? Could DBS eventually help other brain diseases such as Alzheimer's? Alzforum reporter Amber Dance investigates in a new four-part series.

27-May-2010 9:00 AM EDT

Article ID: 564952

Genetic Mutation Associated with Famous Alzheimer Patient May Have Been Identified


Writing the latest pages of an anthropological mystery, scientists propose in this month’s Archives of Neurology that it is highly possible that Auguste Deter, the first identified Alzheimer disease patient, carried the N141I presenilin-2 mutation—the same one as in present-day U.S. families descended from German emigrants who settled near the river Volga in Russia.

25-May-2010 12:25 PM EDT

Article ID: 564854

Protein Regulates Enzyme Linked to Alzheimer’s Disease

Tufts University

Researchers have zeroed in on a protein that may play a role in the progression of Alzheimer’s disease. The team found that increasing levels of the protein prevented the accumulation of an enzyme linked to Alzheimer’s. The strategy may lead to new treatments for the neurodegenerative disease.

25-May-2010 9:00 AM EDT
  • Embargo expired:
    17-May-2010 3:00 PM EDT

Article ID: 564634

New Study Characterizes Cognitive and Anatomic Differences in Alzheimer’s Disease Gene Carriers

Perelman School of Medicine at the University of Pennsylvania

APOEε4 gene carriers with alzheimer’s disease have more memory problems; non-carriers troubled with attention, language and executive function.

17-May-2010 8:00 AM EDT
  • Embargo expired:
    11-May-2010 4:00 PM EDT

Article ID: 564344

Genetic Variations Associated With Alzheimer Disease, But Do Not Help Predict Risk

JAMA - Journal of the American Medical Association

Although genome-wide analysis identified two genetic variations associated with Alzheimer disease (AD), these variations did not improve the ability to predict the risk of AD, according to a study in the May 12 issue of JAMA.

6-May-2010 4:05 PM EDT
  • Embargo expired:
    6-May-2010 3:00 PM EDT

Article ID: 564203

Science Closing in on Mystery of Age-Related Memory Loss, Says UAB Neurobiologist

University of Alabama at Birmingham

The world’s scientific community may be one step closer to understanding age-related memory loss, and to developing a drug that might help boost memory, says UAB neurobiologist David Sweatt in an editorial in Science.

4-May-2010 11:00 AM EDT

Article ID: 564322

More than Half of Liver Patients Have Neurocognitive Impairments

Loyola University Health System

Fifty-four percent of liver patients also display neurocognitive impairments such as short term memory loss, a study found. Average score of impaired patients was lower than that of patients with early-stage Alzheimer's disease.

6-May-2010 11:55 AM EDT

Article ID: 564278

Spouses Who Care for Partners with Dementia at Sixfold Higher Risk of Same Fate

Johns Hopkins Medicine

Husbands or wives who care for spouses with dementia are six times more likely to develop the memory-impairing condition than those whose spouses don’t have it, according to results of a 12-year study led by Johns Hopkins, Utah State University, and Duke University. The increased risk that the researchers saw among caregivers was on par with the power of a gene variant known to increase susceptibility to Alzheimer’s disease, they report in the May Journal of the American Geriatrics Society.

5-May-2010 3:00 PM EDT
  • Embargo expired:
    4-May-2010 9:45 AM EDT

Article ID: 563094

Research Explores the Connection between Normal Pressure Hydrocephalus and Alzheimer’s Disease

American Association of Neurological Surgeons (AANS)

Normal Pressure Hydrocephalus (NPH) is a neurological condition which typically affects adults ages 55 and older. An estimated 5.3 million Americans have Alzheimer’s disease (AD). Research analyzes the connection between NPH and AD, studying tau-protein abnormalities of the brain and the efficacy of shunt placement in these patients.

23-Apr-2010 1:00 PM EDT

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