Feature Channels: Microbiome

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Released: 25-Oct-2019 11:15 AM EDT
Gut Microbiome Is Altered by Burns, Affected by Fluid Resuscitation: New Evidence in SHOCK®
Wolters Kluwer Health: Lippincott

Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK®: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 23-Oct-2019 3:05 PM EDT
Ancient Molecules from the Sea Burst Into the Air From Ocean Waves
Stony Brook University

When waves crash in the ocean, they inject tiny particles into the air that carry organic molecules more than 5,000 years old. This discovery, published in Science Advances by a national team of scientists, helps to solve a long-standing mystery as to what happens to ancient marine molecules.

Released: 23-Oct-2019 11:20 AM EDT
Even the Fetus Has Gut Bacteria, Study Shows
Ann and Robert H. Lurie Children's Hospital of Chicago

A study in humans and mice demonstrated that a fetus has its own microbiome, or communities of bacteria living in the gut, which are known to play important roles in the immune system and metabolism. Researchers also confirmed that the fetal microbiome is transmitted from the mother. These findings open the door to potential interventions during pregnancy to stimulate the fetal microbiome when a premature birth is expected, to help the baby grow faster and be better equipped to tolerate early life infection risk. The study was published in the journal JCI Insight.

9-Oct-2019 4:05 PM EDT
Genetic Differences in the Immune System Shape the Microbiome
University of Chicago

Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.

   
11-Oct-2019 2:20 PM EDT
Unlocking the Biochemical Treasure Chest Within Microbes
Lawrence Berkeley National Laboratory

An international team of scientists lead by the Joint Genome Institute has developed a genetic engineering tool that makes producing and analyzing microbial secondary metabolites – the basis for many important agricultural, industrial, and medical products – much easier than before, and could even lead to breakthroughs in biomanufacturing.

Released: 10-Oct-2019 4:45 PM EDT
Dial In to the Cutting-edge Neuroscience at ANA2019 during the October 15 Media Roundtable
American Neurological Association (ANA)

In a media roundtable at 11 a.m. U.S. Central on Tuesday, October 15, leading neuroscientists will summarize key science being presented at the American Neurological Association’s 2019 Annual Meeting (ANA2019). Reporters may attend in person or dial in.

2-Oct-2019 3:10 PM EDT
Scientists Find Timekeepers of Gut’s Immune System
Washington University in St. Louis

An immune cell that helps set the daily rhythms of the digestive system has been identified by researchers at Washington University School of Medicine in St. Louis. The findings open the door to new treatments for digestive ailments targeting such cells.

Released: 4-Oct-2019 10:05 AM EDT
Charlene Compher, PhD, to Receive 2019 Norma M. Lang Award for Scholarly Practice and Policy
University of Pennsylvania School of Nursing

The award is given biennially to a Penn Nursing faculty member or a graduate from the School’s doctoral program who has made a distinguished contribution to nursing through scholarly practice. It honors Norma M. Lang, PhD, the professor and dean emerita of Penn Nursing for her world-renowned contributions to health policy and practice.

Released: 4-Oct-2019 10:05 AM EDT
Microbiome Provides New Clues to Determining Development of Colon Cancer
George Washington University

Findings showcasing a connection between bacteria in the microbiome and colon cancer, which may be used to screen younger populations at risk, were published in the journal Gastroenterology by researchers from the George Washington University.

Released: 2-Oct-2019 6:05 PM EDT
Tip Sheet: How a failed Alzheimer’s drug boosts CAR T-cell therapy; a new type of anti-CRISPR; and how GVHD starts in the gut
Fred Hutchinson Cancer Center

Below are summaries of recent Fred Hutch research findings, with links for additional background and media contacts.

Released: 1-Oct-2019 2:00 PM EDT
Pivot Bio Joins the International Phytobiomes Allianc
International Phytobiomes Alliance

Pivot Bio has joined the International Phytobiomes Alliance as a sponsoring partner, both organizations announced today.

Released: 1-Oct-2019 11:05 AM EDT
Three UC San Diego Researchers Receive Top Honors with NIH Director’s Awards
UC San Diego Health

Three University of California San Diego researchers have received prestigious awards through the National Institutes of Health (NIH) High-Risk, High-Reward Research Program, including the Pioneer Award, the program’s top honor.

26-Sep-2019 1:05 PM EDT
ORNL scientists shed light on microbial ‘dark matter’ with new approach
Oak Ridge National Laboratory

Scientists at Oak Ridge National Laboratory have demonstrated a way to isolate and grow targeted bacteria using genomic data, making strides toward resolving the grand challenge of uncultivated microbial “dark matter” in which the vast majority of microorganisms remain unstudied in the laboratory.

Released: 30-Sep-2019 9:00 AM EDT
New AI Method May Boost Crohn’s Disease Insight and Improve Treatment
Rutgers University-New Brunswick

Scientists have developed a computer method that may help improve understanding and treatment of Crohn’s disease, which causes inflammation of the digestive tract. The Rutgers-led study, published in the journal Genome Medicine, used artificial intelligence to examine genetic signatures of Crohn’s in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.

19-Sep-2019 3:55 PM EDT
Strip Steak: Bacterial Enzyme Removes Inflammation-Causing Meat Carbohydrates
UC San Diego Health

When we eat red meat, the animal carbohydrate Neu5Gc is incorporated in our tissues, where it generates inflammation. UC San Diego researchers discovered how gut bacteria enzymes strip our cells of Neu5Gc, introducing the possibility of using the enzymes to reduce the risk of inflammatory diseases.

18-Sep-2019 1:05 PM EDT
Microbiome: Pathology’s New Frontier
College of American Pathologists (CAP)

Pathologists are increasingly optimistic about the potential of the human microbiome to help guide diagnosis and monitoring of chronic diseases.

Released: 19-Sep-2019 4:05 PM EDT
ORNL Develops Method to Customize Microbes for Better Biofuel Production
Oak Ridge National Laboratory

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

17-Sep-2019 3:05 AM EDT
For gut microbes, not all types of fiber are created equal
Washington University in St. Louis

Certain human gut microbes with links to health thrive when fed specific types of ingredients in dietary fibers, according to a new study from Washington University School of Medicine in St. Louis. The work — conducted in mice colonized with human gut bacteria and using new technologies for measuring nutrient processing — is a step toward developing more nutritious foods based on a strategy of targeted enrichment of key members of gut microbial communities.

Released: 17-Sep-2019 4:05 PM EDT
Microbiome May Be Involved in Mechanisms Related to Muscle Strength in Older Adults
Tufts University

New study suggests the gut microbiome has a role in mechanisms related to muscle strength in older adults. Researchers found differences in bacterial profiles of older adults with high and low physical function, bacterial and strength differences in mice colonized with fecal samples from the adults.

Released: 12-Sep-2019 10:00 AM EDT
Science Snapshots: messenger proteins, new TB drug, artificial photosynthesis
Lawrence Berkeley National Laboratory

Science Snapshots: messenger proteins, new TB drug, artificial photosynthesis

   
9-Sep-2019 4:05 PM EDT
Microbial Profile to Support Growing Field of Human Gut Research
George Washington University

George Washington University researchers published a comprehensive list of the types and ratios of microbes that inhabit the healthy human gut in PLOS ONE, supporting growing research in the field.

Released: 9-Sep-2019 12:05 PM EDT
Periodontitis Bacteria Love Colon and Dirt Microbes
Georgia Institute of Technology

Mythbuster: The idea that bacterial collaborations within microbiomes, like in the mouth, have evolved to be generous and exclusive very much appears to be wrong. In an extensive experiment, they were possible between random microbes, and members of the same microbiome were stingy with each other.

5-Sep-2019 1:05 PM EDT
Native foods are key to preserving rodent gut bacteria in captivity
University of Utah

If a woodrat is in captivity and is eating an artificial diet, that finely tuned gut microbiome changes. In a paper published in the International Society for Microbial Ecology Journal

Released: 28-Aug-2019 4:05 PM EDT
DOE Announces $64 Million for Research on Plants and Microbes
Department of Energy, Office of Science

The U.S. Department of Energy (DOE) announced $64 million in funding for 25 university-led genomics research projects on plants and microbes for bioenergy and bioproducts.

20-Aug-2019 8:00 AM EDT
Remodeling Unhealthful Gut Microbiomes to Fight Disease
American Chemical Society (ACS)

You are what you eat — right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer.

   
Released: 21-Aug-2019 9:00 AM EDT
Antibiotics Exposure Linked to Increased Colon Cancer Risk
Johns Hopkins Medicine

In an extensive “data mining” analysis of British medical records, researchers at the Johns Hopkins Kimmel Cancer Center conclude that taking even a single course of antibiotics might boost—albeit slightly—the risk of developing colon cancer—but not rectal cancer—a decade later. The findings, reported in the August 20 issue of the journal Gut, highlight the need for judicious use of this broad category of drugs, which are frequently improperly or overprescribed, the report authors say.

12-Aug-2019 11:05 AM EDT
Microbial Fingerprinting
Harvard Medical School

Scientists have analyzed the genetic repertoire of bacteria in the human mouth and gut The effort marks the first chapter in efforts to compile a compendium of all genes in the human microbiome Mapping the microbial genome can reveal links between bacterial genes and disease risk and could inform the development of precision therapies Analysis reveals staggering person-to-person variation in microbial gene content Unique microbial genes, specific to each person, have functions distinct from common, or shared, genes Unique genes may act as a microbe’s evolutionary organ Researchers have made the data publicly accessible at The Universe of Microbial Genes

Released: 13-Aug-2019 11:00 AM EDT
A Community-Driven Data Science System to Advance Microbiome Research
Lawrence Berkeley National Laboratory

The National Microbiome Data Collaborative (NMDC), a new initiative aimed at empowering microbiome research, is gearing up its pilot phase after receiving $10 million from the U.S. Department of Energy Office of Science.

Released: 13-Aug-2019 10:05 AM EDT
Mode of delivery at birth may play key role in shaping the child's skin microbiome
Elsevier

The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood

9-Aug-2019 12:05 PM EDT
Researchers Identify How Vaginal Microbiome Can Elicit Resistance to Chlamydia
University of Maryland School of Medicine

The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections (STIs) in developed countries.

Released: 31-Jul-2019 5:00 PM EDT
Precision Editing of Gut Bacteria Reduces Cancer in Mice
UT Southwestern Medical Center

UT Southwestern researchers have shown that precision editing of the bacterial populations in the gut reduces inflammation-associated colorectal cancer in mice.

Released: 30-Jul-2019 2:00 PM EDT
Joyn Bio Joins the International Phytobiomes Alliance
International Phytobiomes Alliance

Joyn Bio has joined the the International Phytobiomes Alliance, both organizations announced today

21-Jul-2019 8:00 PM EDT
These Gut Bacteria Prevent Obesity in Mice. What Could That Mean for Us?
University of Utah Health

A specific class of bacteria from the gut prevents mice from becoming obese, suggesting these same microbes may similarly control weight in people, a new study reports. The beneficial bacteria, called Clostridia, are part of the microbiome — collectively trillions of bacteria and other microorganisms that inhabit the intestine. University of Utah Health investigators led the study which publishes online in the journal Science on July 25.

Released: 24-Jul-2019 4:05 PM EDT
3D printed pill samples gut microbiome to aid diagnosis and treatment
Tufts University

A research team led by Tufts University engineers has developed a 3D printed pill that samples bacteria found in the gut -- known as the microbiome -- as it passes through the gastrointestinal tract (GI). The ability to profile bacterial species throughout the GI tract could have important implications for the diagnosis and treatment of many diseases.

23-Jul-2019 12:05 PM EDT
QIIME 2: NAU team reengineers bioinformatics software for next generation of microbiome science
Northern Arizona University

Greg Caporaso and his team are changing how scientists study microbiomes with a remake of his groundbreaking open-share software program called QIIME 2.

Released: 23-Jul-2019 4:15 PM EDT
Gut Microbes May Affect the Course of ALS
Weizmann Institute of Science

Profs. Eran Elinav and Eran Segal at the Weizmann Institute of Science have isolated a molecule that may be under-produced in the guts of ALS patients

8-Jul-2019 6:05 PM EDT
For malnourished children, new therapeutic food boosts gut microbes, healthy development
Washington University in St. Louis

A new type of therapeutic food, specifically designed to repair the gut microbiomes of malnourished children, is superior to standard therapy in an initial clinical trial conducted in Bangladesh.

Released: 11-Jul-2019 1:05 PM EDT
New Virus Found in One-Third of All Countries May Have Coevolved with Human Lineage, Study Finds
University of Notre Dame

Published in Nature Microbiology, a new study has investigated the origin and evolution of a virus called crAssphage, which may have coevolved with human lineage.

   
Released: 9-Jul-2019 4:05 PM EDT
Growth Failure in Preterm Infants Tied to Altered Gut Bacteria
Ann and Robert H. Lurie Children's Hospital of Chicago

Extremely premature infants who fail to grow as expected have delayed development of their microbiome, or communities of bacteria and other micro-organisms living in the gut, according to a new study published in Scientific Reports. Analysis of these infants’ metabolism revealed that their bodies are responding as if they were fasting, despite caloric intake similar to extremely premature infants with appropriate growth. The study findings also suggest that the unique makeup of the microbiome in infants with growth failure might contribute to their inability to properly metabolize nutrients.

Released: 8-Jul-2019 4:05 PM EDT
Augustana University Professor’s Research Leads to Surprising Mating Decision in Butterfly Species
Augustana University, South Dakota

The males of one species of butterfly are more attracted to females that are active, not necessarily what they look like, according to a recent research conducted at Augustana University.The paper, “Behaviour before beauty: Signal weighting during mate selection in the butterfly Papilio polytes,” found that males of the species noticed the activity levels of potential female mates, not their markings.

Released: 8-Jul-2019 3:50 PM EDT
Beneath the Earth, the ‘Black Box’ of Soil Holds a Key to Crop Growth
University of Florida Institute of Food and Agricultural Sciences

Farmers use fertilizer to put nutrients into their soil to help crops grow. When nutrients get into the soil, microbes can help plants grow by changing nutrients into other forms, such as nitrate or ammonium, that plants either use or are leached out of the soil, Strauss said. Other microbes give the soil more nutrients by providing new sources of nitrogen that can also benefit plants.

Released: 25-Jun-2019 11:05 AM EDT
Performance-Enhancing Bacteria Found in the Microbiomes of Elite Athletes
Joslin Diabetes Center

BOSTON – (June 24, 2019) -- New research has identified a type of bacteria found in the microbiomes of elite athletes that contributes to improved capacity for exercise. These bacteria, members of the genus Veillonella, are not found in the guts of sedentary people. By taking a closer look at the bacteria, the researchers from Joslin Diabetes Center determined Veillonella metabolizes lactic acid produced by exercise and converts it into propionate, a short chain fatty acid.

21-Jun-2019 8:00 PM EDT
Scientists hit pay dirt with new microbial research technique
Lawrence Berkeley National Laboratory

Long ago, during the European Renaissance, Leonardo da Vinci wrote that we humans “know more about the movement of celestial bodies than about the soil underfoot.” Five hundred years and innumerable technological and scientific advances later, his sentiment still holds true. But that could soon change. A new study in Nature Communications details how an improved method for studying microbes in the soil will help scientists understand both fine-grained details and large-scale cycles of the environment.

Released: 21-Jun-2019 5:00 AM EDT
Blue Pigment from Engineered Fungi Could Help Turn the Textile Industry Green
Lawrence Berkeley National Laboratory

A new biosynthetic production pathway developed by scientists at the Joint BioEnergy Institute could provide a sustainable alternative to conventional synthetic blue dye. The highly efficient fungi-based platform may also open the door for producing many other valuable biological compounds that are currently very hard to manufacture.

Released: 18-Jun-2019 9:00 AM EDT
Intrexon Corporation and Surterra Wellness Partner in $100mm Deal to Advance Commercial Scale Fermentation-based Cannabinoid Production
Intrexon Corporation

Intrexon Corporation (Intrexon) (NASDAQ: XON), a leader in the engineering and industrialization of biology to improve quality of life and health of the planet

   
Released: 14-Jun-2019 2:05 PM EDT
The gut microbiota and epilepsy: Intriguing research and the road ahead
International League Against Epilepsy

An increasing number of studies are finding intimate communication between the gut and brain, as well as complex interplay among the gut microbiome, the brain and the rest of the body. But does the gut affect epilepsy? More specifically, can certain populations of bacteria predispose to seizures, and can we harness the power of the microbiome to stop seizures?

Released: 13-Jun-2019 8:05 AM EDT
Martin J. Blaser To Receive Robert Koch Gold Medal for Contribution to Medicine
Rutgers University-New Brunswick

Martin J. Blaser, director of Rutgers University’s Center for Advanced Biotechnology and Medicine whose research led to new understandings about the beneficial relationships between humans and their microbiome (the microbes that live on and in our bodies), will receive the 2019 Robert Koch Gold Medal for his life’s work, the Robert Koch Foundation has announced.

Released: 12-Jun-2019 8:45 AM EDT
iTHRIV Awards Pilot Funding, Supports Statewide Research Collaborations
University of Virginia Health System

The integrated Translational Health Research Institute of Virginia (iTHRIV) has awarded funding to four multi-institutional research projects through the Pilot Translational and Clinical Studies Program.

Released: 11-Jun-2019 2:00 PM EDT
Valent BioSciences Joins the International Phytobiomes Alliance
International Phytobiomes Alliance

Valent BioSciences Joins the International Phytobiomes Alliance, both partners announced today

Released: 6-Jun-2019 12:30 PM EDT
Berkeley Lab Technology Provides Clarity Amid Hawaiian Water Contamination Concerns
Lawrence Berkeley National Laboratory

For years, routine testing has shown that watersheds of the Mahaulepu Valley and Waikomo Stream in southeast Kauai frequently contain high counts of potentially pathogenic fecal indicator bacteria (FIB). To better understand the cause of the high FIB counts, the DOH commissioned a study by Berkeley Lab microbial ecologists Gary Andersen and Eric Dubinsky. After using a powerful microbial detection tool called the PhyloChip, the scientists concluded that most of the past monitoring results were false positives.



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