Feature Channels: AIDS and HIV

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As the number of sexually transmitted infections (STIs) sharply rises in the U.S., new evidence suggests that a common antibiotic—doxycycline—could help prevent the spread of some bacterial infections.

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The National Institutes of Health (NIH) has granted $2.1 million to UCLA’s Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and the UCLA-CDU Center for AIDS Research (CFAR) to support four research projects and an implementation science consultation hub.

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Investigators from Cedars-Sinai have made two important discoveries about fiber and the gut microbiome in patients with human immunodeficiency virus, or HIV.

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People living with HIV may face hard choices when balancing their own health needs with caring for a pet, a study led by a University of Florida College of Public Health and Health Professions researcher finds.

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Across Africa about two million premature deaths each year are caused by the effects of diabetes and hypertension.

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A four-year, $2.9 million grant to assess the implementation of real-time health intervention to decrease substance use and support HIV prevention strategies in young adults experiencing homelessness.

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Below are some of the latest headlines in the Women's Health channel on Newswise.

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University of Delaware researchers conducted exhaustive studies of human papillomavirus (HPV), the most common sexually transmitted infection (STI) in the world. They confirmed 25 different types of HPV prevalent in Nigeria, a discovery that underscores the need for more region-specific vaccines.

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A research team shows for the first time that HIV reservoirs are concentrated in the spleen and lymph nodes, and that they can travel throughout the body.

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Among African American and other Black cisgender women, a beauty salon–based intervention improved knowledge and awareness of pre-exposure prophylaxis (PrEP) against HIV and increased trust in it.

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The Center for Immunization and Infection Research in Cancer at Moffitt Cancer Center is expanding its viral infection research in Africa. The cancer center has received a $5.5 million, five-year specialized research center grant (U54CA277834) from the National Cancer Institute to investigate virus-associated tumors that disproportionately impact men and women living with HIV in sub-Saharan Africa.

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Tufts University School of Medicine teams and collaborators are running multiple projects that seek to reduce overdoses and the spread of infections, such as HIV and hepatitis C, in people who use drugs

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An initiative of Wits University’s MRC/Wits Agincourt Research Unit, the Traditional Healers Project convened two ‘open houses’ at local primary healthcare facilities – Rolle Clinic and Thulamahashe Community Health Centre in rural Bushbuckridge, Mpumalanga – in March 2023.

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As doenças sexualmente transmissíveis (DSTs) continuam a aumentar nos EUA e ao redor do mundo. A Organização Mundial da Saúde relata que mais de 1 milhão de novas doenças sexualmente transmissíveis são adquiridas diariamente, sendo que a maioria delas é assintomática.

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Las infecciones de trasmisión sexual (ITS) siguen aumentando en los EE. UU. al igual que en el resto del mundo. Según la Organización Mundial de la Salud, hay más de un millón de nuevas infecciones de trasmisión sexual al día, la mayoría de las cuales son asintomáticas.

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UNC School of Medicine researchers Angela Wahl, PhD, Balfour Sartor MD, J. Victor Garcia, PhD, and colleagues created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases.

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An international team of researchers has found a genetic variant that may explain why some people of African ancestry have naturally lower viral loads of HIV, reducing their risk of transmitting the virus and slowing progress of their own illness.

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Hip replacement surgery is safe for patients living with human immunodeficiency virus (HIV), researchers at UT Southwestern Medical Center found.

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Based on findings from a study published today in the journal, The Lancet Regional Health – Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.

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Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.

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High rates of smoking among people with HIV are associated with high rates of comorbid health problems – which are associated with characteristics including gender, race/ethnicity, and socioeconomic status, according to a study in the July issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

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Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines have identified an enzyme that plays a critical role in the late stages of HIV replication.

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Wistar hosts its 27th Jonathan Lax Memorial Lecture Thursday, June 29th at 5:30 pm EST.

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Researchers from the University of Illinois Chicago used the Theta supercomputer at the Argonne Leadership Computing Facility to run simulations on and determine the molecular mechanisms behind the ways that new HIV antivirals could work.

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New research published in the Journal of Clinical Investigations confirms that microglial cells – which are specialized immune cells with a decade-long lifespan in the brain - can serve as a stable viral reservoir for latent HIV.

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Researchers at the UNC School of Medicine’s International Center for the Advancement of Translational Science and the Institute for Global Health and Infectious Diseases have developed a new approach for the detailed evaluation of HIV infection throughout the entire male genital tract, HIV acquisition via the penis and the efficient prevention of penile HIV infection. The study was published in mBio by the American Society of Microbiology.

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Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. If you’re covering the American Society for Clinical Oncology’s annual meeting, June 2-6 in Chicago, Illinois, see our list of Fred Hutch research highlights at ASCO and contact [email protected] to set up interviews with experts.

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Read about new melanoma treatment practices, how models provide information about a rare adrenal cancer, a potential oral medication for brain cancer, and clinical trials for cancer patients with HIV.

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Scientists have spent years trying to develop an effective HIV vaccine, but none have proven successful. Based on findings from a recently published study, a Johns Hopkins Medicine-led research team may have put science one step closer to that goal.

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Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.

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An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor.

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Rutgers Institute for Health researcher, Dr. Ashley Grosso, receives grant from NIH to conduct study on barriers to HIV research in Africa.

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Patients with mpox who were treated with the antiviral drug tecovirimat had similar outcomes regardless of HIV status, find researchers at Columbia University and Weill Cornell Medicine.