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Article ID: 696615

Proteins Found in Semen Increase the Spread of Ebola Virus Infection

Perelman School of Medicine at the University of Pennsylvania

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Follow-up studies from the 2014 epidemic found that men can harbor the virus in their semen for at least 2.5 years, with the potential to transmit the virus sexually during that time. Targeting amyloids in semen may prevent a sexually transmitted spread of the Ebola virus.

Released:
25-Jun-2018 3:50 PM EDT
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Article ID: 694538

Vaccine-Induced Antibodies Against One Hemorrhagic Fever Virus Found to Disarm Related Virus for Which There Is No Vaccine

Harvard Medical School

Research conducted in vitro shows two human antibodies made in response to vaccination against one hemorrhagic fever virus can disarm a related virus, for which there is currently no vaccine. The proof-of-principle finding identifies a common molecular chink in the two viruses’ armor that renders both vulnerable to the same antibodies. The results set the stage for a single vaccine and other antibody-based treatments that work against multiple viral “cousins” despite key differences in their genetic makeup. Such therapies can alleviate challenges posed by current lack of vaccines and prevent outbreaks of viral hemorrhagic fevers.

Released:
14-May-2018 2:30 PM EDT
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Article ID: 694529

Mapping the Body’s Battle with Ebola and Zika

Los Alamos National Laboratory

The viruses that cause Ebola and Zika, daunting diseases that inspire concern at every outbreak, share a strong similarity in how they first infiltrate a host’s cells.

Released:
14-May-2018 12:05 PM EDT
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Article ID: 691734

Researchers Identify Chemical Compound That Inhibits Ebola Virus Replication

Georgia State University

An organic chemical compound shows effective antiviral activity against Ebola virus and several other viruses, according to a study led by Georgia State University.

Released:
26-Mar-2018 3:05 PM EDT
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  • Embargo expired:
    22-Feb-2018 9:30 AM EST

Article ID: 689866

Promising Treatment for Ebola Virus to be Tested at Texas Biomed

Texas Biomedical Research Institute

During the West African Ebola outbreak that began in 2013, an experimental biopharmaceutical drug called ZMappTM was a glimmer of hope in the midst of a health crisis. Now, scientists at Texas Biomedical Research Institute in San Antonio have been awarded a $2 million dollar contract by the makers of ZMapp, Mapp Biopharmaceutical, Inc., to further test this promising new therapeutic.

Released:
20-Feb-2018 4:15 PM EST
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Article ID: 689655

TSRI Scientists Receive $15 Million to Study Viral Outbreak Survivors

Scripps Research Institute

The researchers will spend the next five years collecting data from Ebola and Lassa survivors to learn how they fought off the virus.

Released:
15-Feb-2018 5:05 PM EST
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  • Embargo expired:
    10-Jan-2018 12:00 PM EST

Article ID: 687718

TSRI Scientists Discover Workings of First Promising Marburg Virus Treatment

Scripps Research Institute

Scientists at The Scripps Research Institute have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus.

Released:
9-Jan-2018 5:05 PM EST

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