Philadelphia, February 11, 2019 - As marijuana legalization sweeps North America, use of the substance has been on the rise, and the public's attitude is shifting. An increasing number of people believe that "weed" is the safest recreational drug, one that carries health benefits that outweigh its risks.
The Wistar Institute announces that it was awarded more than $16M in federal research funds in support of its groundbreaking research in cancer, immunology and infectious diseases.
A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.
Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
Researchers have pinpointed how fibrosis develops in butterfly syndrome patients. The discovery points to a potential treatment for the debilitating complication.
Companies that improve their "culture of health" realize some important benefits, including reductions in employee health risk factors, medical visits, prescription drug use, and healthcare costs, reports a study in the February Journal of Occupational and Environmental Medicine.
An international team of collaborators found that the CD4 surface protein, which is used by HIV and SIV as the receptor to enter immune cells, is highly variable among wild chimpanzees.
Wolters Kluwer, Health announced today that the Journal of Psychosocial Oncology Research & Practice, the newest journal of the International Psycho-Oncology Society (IPOS), will be published under the Lippincott portfolio.
In this role, Marion Leary, MSN, MPH, RN FAHA, will design and execute innovation programs and projects through Penn Nursing’s Office of Nursing Research (ONR) and will work to keep the School at the forefront of innovation in nursing. The appointment was effective February 1, 2019.
University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.
Researchers have successfully identified two genetic markers for potentially effective treatment of Mesothelioma, an orphan disease most commonly associated with asbestos exposure, and for which few treatments exist.
The National Comprehensive Cancer Network® (NCCN®) announces formal endorsements from the governments of Ethiopia, Nigeria, and Tanzania for the NCCN Harmonized Guidelines™ for Sub-Saharan Africa, while joining cancer leaders across the globe to raise awareness and take action for World Cancer Day on February 4.
In a study of over 12,000 lines of fruit flies, researchers from the Perelman School of Medicine at the University of Pennsylvania have found a single gene, called nemuri, that increases the need for sleep.
As part of a longstanding partnership with the UAE’s Ministry of Health and Prevention, Children’s Hospital of Philadelphia, a global leader in pediatric healthcare, exhibited some of its leading medical breakthroughs in the Ministry booth at the annual Arab Health Exhibition and Congress, in the Dubai International Convention and Exhibition Centre.
Plastic surgeons have long debated the mechanisms aging-related changes in the face: Are they related more to "deflation" or "sagging"? A new study helps settle the debate, showing significant loss of volume in the upper lip in older adults, reports the February issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Implants are usually the first choice for breast reconstruction after mastectomy. But when implant-based reconstruction fails, autologous reconstruction – using the patient's own tissues – is a safe procedure that improves patient outcomes, reports a study in the February issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
With a lower risk of serious complications and improved feeding and growth outcomes, human milk is strongly preferred as the best diet for infants with congenital heart disease (CHD), according to a research review in Advances in Neonatal Care, official journal of the National Association of Neonatal Nurses. The journal is published in the Lippincott portfolio by Wolters Kluwer.
As the opioid epidemic continues to plague the United States, physician-researchers at Children’s Hospital of Philadelphia analyzed prescription patterns in children. They found that both duration of treatment and dose amounts declined between 2013 and 2017, while the rate of prescribing remained the same.
The National Comprehensive Cancer Network® (NCCN®) has published updated resources for improving and facilitating quality, effective, efficient, and accessible cancer care in the Middle East and North Africa (MENA).
The type of saturated fats we eat can affect our risk of a heart attack, according to a study published in the International Journal of Cardiology. People whose diets contain relatively little palmitic and stearic acid - saturated fats composed of 16 or more carbon atoms (longer-chain saturated fats) that are typically found in meats - and eat plant-based proteins instead have decreased chances of myocardial infarction.
A novel “Enhanced Recovery After Surgery” (ERAS) protocol developed by Penn Medicine for patients undergoing spinal and peripheral nerve surgery significantly reduced opioid use. The new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was employed fewer patients needed pain medications one month after surgery.
– Based on limited research, there's no strong evidence that selective serotonin-reuptake inhibitors (SSRIs) – the most widely used class of antidepressants – have an adverse impact on fertility, according to a paper in the Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Wistar scientists and collaborators demonstrated the utility of an optimized synthetic DNA vaccine platform for rapidly inducing immunity against unique combinations of tumor neoantigens.
Implementing a new recovery pathway speeds time to next treatment for pancreatic cancer patients by 15 days, without increasing complication rates.
Over a year and a half after the successful separation of two infant twins joined at the top of their heads, surgical team leaders report on this dramatic case. The surgeons describe the innovative devices, elaborate planning and precisely orchestrated teamwork needed to perform the complex separation surgery.
If a patient has private insurance, doctors can get prior approval to prescribe a drug “off-label” to make sure the medication will be covered, but these lists are incomplete, outdated, and frequently in conflict with each other.
Researchers from Yale School of Public Health find that genetic profiling for cancer tumors is cost-effective for high- and medium-risk patients with breast cancer, but is unlikely to make a meaningful impact on treatment for low-risk patients, in study published in January 2019 issue of JNCCN-Journal of the National Comprehensive Cancer Network
Philadelphia, January 22, 2019 - Nearly a quarter of employed adults obtain foods and beverages at work at least once a week, according to a new study from the US Centers for Disease Control and Prevention (CDC) and published in the Journal of the Academy of Nutrition and Dietetics. Foods obtained at work are often high in calories, refined grains, added sugars, and sodium.
An approved drug that blocks an integrated stress response shows promise in preliminary tests against ALS and frontotemporal dementia.
Researchers at the Abramson Cancer Center of the University of Pennsylvania say they’ve identified how to fuel macrophages with the energy needed to attack and eat cancer cells.
An automated text messaging system increases patient engagement with home-based exercise and promotes faster recovery after total knee or hip replacement surgery, reports a study in the January 16, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
The marketing of direct-to-consumer “neurotechnologies” can be enticing: apps that diagnose a mental state, and brain devices that improve cognition or “read” one’s emotional state. However, many of these increasingly popular products aren’t fully supported by science and have little to no regulatory oversight, which poses potential health risks to the public. In a new piece published in the journal Science this week, two bioethicists from Penn Medicine and the University of British Columbia suggest the creation of a working group that would further study, monitor, and provide guidance for this growing industry – which is expected to top $3 billion by 2020.
Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children’s Hospital of Philadelphia. The patients used less than 25 percent of the drugs, suggesting a potential risk of opioid diversion.
The Pennsylvania Pediatric Medical Device Consortium announces a partnership with two programs at the University of Pittsburgh. Formerly the Philadelphia Pediatric Medical Device Consortium, the PPDC’s new name reflects its statewide reach. The expansion follows a five-year $6 million grant renewal from the FDA.
The use of antibiotics to treat inflammatory skin conditions like acne and rosacea is decreasing over time, but there has been an increase in prescriptions associated with dermatologic surgical procedures.
The Abramson Cancer Center at the University of Pennsylvania announced today that Richard S. Schiffrin, Esq., has been appointed chair of the Center Director’s Leadership Council.
The National Comprehensive Cancer Network® (NCCN®) announced that the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) were downloaded more than 10 million times in 2018; marking a 26% increase over 2017.
As US rates of marijuana use continue to rise, workers who use marijuana may be at higher risk of losing their jobs, suggests a study in the January Journal of Occupational and Environmental Medicine.
Bullying in the workplace increases employees' psychological distress and plans to quit their job—even for workers who aren't personally being bullied, reports a study in the December Journal of Occupational and Environmental Medicine.
Total Worker Health (TWH) is a holistic approach to improving well-being in the American workforce. Recommendations from an expert workshop seeking to strengthen the evidence supporting TWH interventions are presented in a special article in the November Journal of Occupational and Environmental Medicine.
The collaborative research between the Kornberg School of Dentistry and the College of Engineering uses stem cells to regrow the pulp-dentin complex that makes up the center of a tooth.
The increase in opioid prescriptions for people over the past decade may have been paralleled by an increase in opioid prescriptions for pets, according to a study from researchers at the University of Pennsylvania’s Perelman School of Medicine and the School of Veterinary Medicine. The findings, in this first-ever study of veterinary opioid prescriptions, suggest that there is also an increased demand for veterinary opioids, driven by complex procedures performed in veterinary medicine, as well as a heightened awareness of the importance of pain management. Given that opioid prescribing in veterinary medicine is not as heavily regulated as medical prescriptions for humans, it is possible that misused veterinary prescriptions could contribute to the ongoing opioid epidemic. The results are published today in JAMA Network Open.
Researchers have demonstrated—using fat cells derived from human stem cells—that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain individuals.
Maria A. Oquendo, MD, PhD, is probing the human mind and brain to prevent more lives from being lost to the tenth leading cause of death in the United States.
Astronauts who spend several months on the International Space Station have significant reductions in the size and density of paraspinal muscles of the trunk after returning to Earth, reports a study in Spine. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Wistar, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc. announce the FDA has approved the initiation of a first-in-human clinical trial investigating safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody (DMAb) therapeutic technology for the prevention of Zika virus infection.
London, January 8, 2019 - As social networking activity has become pervasive, researchers have been taking a closer look at its impact on our psychological and physical health. A new study published in the journal Heliyon examines how Facebook users interpret the information they derive from social comparisons and how this process correlates with their perceptions of physical health. The results show that Facebook use and social comparison are associated with a greater awareness of physical ailments.
With $13.4 million dollars in awards from the National Institutes of Health (NIH), the University of Pennsylvania School of Nursing (Penn Nursing) retains its top spot for research funding for the 2018 fiscal year, among other schools of nursing. This is the second consecutive year Penn Nursing has earned first place.
For surgeons getting ready to enter the operating room (OR), the chances of contamination may be lower if they put their gowns on by themselves – without the assistance of a surgical technician, according to an experimental study in the Journal of Orthopaedic Trauma. The journal is published in the Lippincott portfolio by Wolters Kluwer.
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