A team of researchers from The University of Texas at El Paso found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
As part of a five-year, $3.9 million grant from the National Institutes of Health, Adriana Pérez, PhD, professor in the Department of Biostatistics and Data Science with UTHealth Houston School of Public Health in Austin, received a $1.9 million subcontract to determine the scope and drivers of low-value and unequal care for patients with Parkinson’s disease and Parkinson’s disease dementia.
Researchers performed complementary experiments showing that inhibiting a specific enzyme in a mouse model protects the dopamine-producing neurons that are normally lost as Parkinson's disease progresses, effectively halting the progression of the disease. The findings open the door to the development of novel therapeutics targeting the enzyme that may slow or prevent the progression of Parkinson's disease in people—a major unmet need.
Associated with slower disease progression and lower doses of required drugs
Published in Environment International, a groundbreaking study from the Institute of Biological Chemistry and Centre for Microbiology and Environmental Systems Science (CeMESS) at the University of Vienna, in collaboration with the University of Konstanz and the Albert Einstein College of Medicine, reveals a microbial metabolite's role in inducing Parkinson's-like symptoms.
Until recently, our understanding of Parkinson's disease has been quite limited, which has been apparent in the limited treatment options and management of this debilitating condition.
Below are some of the latest headlines in the Women's Health channel on Newswise.
The cyanobacterial origin of β-N-methylamino-L-alanine (BMAA), an environmental neurotoxin, remains controversial. With a carefully designed genetic system as a control, we found no evidence for the production of BMAA by cyanobacteria from lab cultures or bloom samples.
ParkinSINGs Program at JFK Johnson Rehabilitation Center Receives Support from Parkinson’s Foundation
Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.
A new Northwestern Medicine study challenges a common belief in what triggers Parkinson’s disease. Degeneration of dopaminergic neurons is widely accepted as the first event that leads to Parkinson’s.
Even the best treatment approaches for Parkinson’s disease are inadequate if they do not address patients’ feelings of social rejection, isolation, loneliness and other psychosocial effects of stigma, according to a report from experts specializing in Parkinson’s and other movement disorders.
SMU biology professor Zhihao Wu has received a $1.8 million, 5-year Maximizing Investigators' Research Award (MIRA) from the National Institutes of Health to determine if different quality control pathways in our bodies might be working together to repair damaged components in cells.
A recent study by the University of Eastern Finland and Balettakademien Stockholm found that performing in a dance company and being involved in its activities play a significant role in the identity and disease-related identity negotiation in people with Parkinson’s disease.
Scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.
The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson’s. Project participant and Parkinson's advocate Ethan Henderson can comment.
En julio, salió al mercado el primer análisis de sangre directo al consumidor diseñado para evaluar el riesgo de un usuario de desarrollar la enfermedad de Alzheimer.
In July, the first direct-to-consumer blood test designed to assess a user’s risk for developing Alzheimer’s disease hit the market.
Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of the molecular changes that take place in the brain to cause it. Now, a study in mice has determined that the most pronounced changes occur in the white matter, a type of nervous system tissue that’s integral to transmitting signals across the brain.
Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson’s disease using images of patient-derived stem cells.
Robert E. Gross, MD, PhD, a renowned neurosurgeon who has led collaborative teams of clinician-scientists in the pursuit of improving the quality of life for patients with neurological and psychiatric disorders, has been appointed joint chair of the Department of Neurosurgery at Rutgers Health. Gross also will serve as the senior vice president for neurosurgical services at RWJBarnabas Health.
Scientists from the Immanuel Kant Baltic Federal University and Skolkovo Institute of Science and Technology have found that the use of brain-computer interfaces can help speed up the rehabilitation of patients who have suffered a stroke.
Findings of a new study show digital health serves as an additional health service resource, which increases the healthcare provider’s abilities to collect current visual and objective data, thereby decreasing patient and caregiver burden and medical expenses.
Accumulation and deposition of amyloid can cause a variety of neurodegenerative diseases, including Alzheimer's and Parkinson's disease. The degradation of this accumulation is the most widely accepted therapeutic strategy. The study on amyloid-β (Aβ) oligomers in vitro found that high-frequency terahertz (THz) wave at a specific frequency could be served as a physical, efficient, nonthermal denaturation way to delay the fibrotic process with a speed of 80 per cent.
The Annals of Neurology study led by Mallory Hacker, PhD, MSCI, assistant professor of Neurology, with senior author David Charles, MD, professor and vice-chair of Neurology, may offer new hope to the nearly 100,000 new cases of Parkinson’s diagnosed each year.
Feathers, fins or fur, all pets can make us feel happier. Now, new research from the University of South Australia shows that pet ownership and pet care can also support communication and wellbeing, especially for people with acquired language difficulties such as aphasia.
Parkinson's disease, another neurodegenerative process, produces in patients a unique smell, which trained dogs can detect. Alzheimer's disease, the leading dementia, needs to be similarly studied. This $200,000 challenge award is posted to help stimulate this necessary research.
It's fragile X awareness month, and the NIH has renewed funding for a key study of the neurodegenerative condition fragile X-associated tremor ataxia syndrome (FXTAS).
Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test.
What makes the vital layer of protective cells around the brain and spinal cord — the blood-brain barrier — more or less permeable has been one of the more mystifying questions in neuroscience.
Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer’s, Parkinson’s or Huntington’s disease.
Researchers from WEHI (Walter and Eliza Hall Institute) in Melbourne have solved a long-standing mystery about how a protein helps rid the body of damaged mitochondria, in findings that could help lead to potential new treatments for Parkinson’s disease.
The brain and the digestive tract are in constant communication, relaying signals that help to control feeding and other behaviors. This extensive communication network also influences our mental state and has been implicated in many neurological disorders.
Beta-2 agonists are bronchodilators commonly used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Fatigue is the symptom that most significantly impacts the daily lives of long Covid patients, and can affect quality of life more than some cancers, finds a new study led by researchers at UCL and the University of Exeter.
According to a study published in Cell Reports, the tiny implantable devices formed stable, long-lasting and seamless tissue-electrode interfaces with minimal scarring or degradation in rodents.
The risk of side effects can rise if drugs are taken for conditions other than Alzheimer's disease (AD) treatment. Some sedatives and antidepressants can deteriorate cognitive function, make people drowsy and confused, and worsen cognitive impairment, which increases the risk of falls.
Getting regular exercise such as cycling, walking, gardening, cleaning and participating in sports may decrease the risk of developing Parkinson’s disease, according to new research published in the May 17, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found female participants who exercised the most had a 25% lower rate of Parkinson’s disease when compared to those who exercised the least. The study does not prove that exercise lowers the risk of developing Parkinson’s disease. It only shows an association.
Through a novel pairing of epidemiology and toxicity screening, UCLA and Harvard researchers were able to identify 10 pesticides that were directly toxic to key neurons.
Impairments in the lymphatic system may contribute to brain diseases, such as neurodegenerative diseases and stroke. Researchers have found a noninvasive and nonpharmaceutical method to influence glymphatic transport using focused ultrasound, opening the opportunity to use the method to further study brain diseases and brain function.
Using artificial intelligence (AI) to process natural language, a research group evaluated the characteristics of speech among patients with Parkinson’s disease (PD).
Scientists from UNSW Sydney with collaborators at Boston University have developed a tool that shows early promise in detecting Parkinson’s disease years before the first symptoms start appearing.
University of Minnesota Twin Cities researchers have developed a groundbreaking new diagnostic technique that will allow for faster and more accurate detection of neurodegenerative diseases that affect humans, such as Alzheimer's and Parkinson's, and similar diseases that affect animals, such as chronic wasting disease (CWD) and mad cow disease.
In Sörmland, Sweden, music therapy is offered as a method of treatment for people living with chronic pain. Currently, the effects of what is known as the FMT method are being investigated through a research project at Mälardalen University (MDU).
This agreement will enable FAU and Insightec to collaborate to advance scientific knowledge about the use of focused ultrasound to treat brain diseases, including Parkinson’s disease and Alzheimer’s disease. By harnessing acoustic energy, Insightec’s innovative technology uses focused ultrasound to treat diseases in different ways.
Researchers at the University of Delaware ran an fMRI study to investigate the neural correlates of lower limb movements in individuals with and without PD. Groundbreaking research demonstrates that multiple motor regions in the brain are underactive during lower limb movements in people with Parkinson’s disease.
Led by Lukas Kenner (Department of Pathology at MedUni Vienna and Department of Laboratory Animal Pathology at Vetmeduni) and Oldamur Hollóczki (Department of Physical Chemistry, University of Debrecen, Hungary) the research team was able to determine that tiny polystyrene particles could be detected in the brain just two hours after ingestion. The mechanism that enabled them to breach the blood-brain barrier was previously unknown to medical science.
Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.
While strategies for regenerating or replacing lost neurons from stem cells are being developed, an alternative treatment option is the protection of existing neurons to prevent their degeneration, a recent study published in Stem Cell Reports suggests.
Rigshospitalet and Aarhus University have joined forces with the Danish health technology company, T&W Engineering, and they have just received DKK 15 million in funding from Innovation Fund Denmark for their potentially ground-breaking project for people with serious brain diseases.
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