Feature Channels: Alzheimer's and Dementia

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2-Jan-2024 10:05 AM EST
Even in Midlife, Disrupted Sleep Tied to Memory, Thinking Problems Later On
American Academy of Neurology (AAN)

People who have more disrupted sleep in their 30s and 40s may be more likely to have memory and thinking problems a decade later, according to new research published in the January 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that sleep quality causes cognitive decline. It only shows an association.

Released: 2-Jan-2024 2:05 PM EST
Researchers identify new coding mechanism that transfers information from perception to memory
Dartmouth College

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.

Newswise: Evidence early, but emerging, that gamma rhythm stimulation can treat neurological disorders
Released: 20-Dec-2023 3:05 PM EST
Evidence early, but emerging, that gamma rhythm stimulation can treat neurological disorders
Picower Institute for Learning and Memory at MIT

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer’s disease.

Released: 20-Dec-2023 1:05 PM EST
WRQ Sciences and Superfluid Dx., Inc. Announce Completion of Oversubscribed Series A Financing in Breakthrough Alzheimer's Disease Diagnostic Company Superfluid Dx
Superfluid Dx

WRQ Sciences and Superfluid Dx, Inc., announced today the completion of an oversubscribed Series A financing led by WRQ Sciences. With this transaction, WRQ Sciences has acquired majority ownership in the Alzheimer's Disease (AD) diagnostics company, Molecular Stethoscope, Inc., which is now renamed Superfluid Diagnostics, Inc. The Alzheimer's Drug Discovery Foundation's (ADDF) Diagnostics Accelerator (DxA) participated in the Series A financing.

Newswise: Alzheimer’s discovery reveals dire effect of toxic tau protein on brain cells
Released: 20-Dec-2023 12:05 PM EST
Alzheimer’s discovery reveals dire effect of toxic tau protein on brain cells
University of Virginia Health System

University of Virginia Alzheimer’s researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

Released: 20-Dec-2023 12:05 PM EST
Digital training program improves quality of life for care residents with dementia – even during the COVID-19 pandemic
University of Exeter

Quality of life for people with dementia living in residential and nursing home care substantially improved after staff took part in a digital training programme that was specially adapted to Covid-19 restrictions. The training also led to a significant drop in the prescription of potentially harmful sedative medications to residents.

Newswise: Caring for loved ones with dementia, Alzheimer's disease during the holidays
Released: 19-Dec-2023 7:05 PM EST
Caring for loved ones with dementia, Alzheimer's disease during the holidays
University of California, Los Angeles (UCLA), Health Sciences

UCLA Health dementia care specialists say caregiving and holiday festivities do not have to be mutually exclusive, but do require some adaptations to make the season enjoyable for all.

Released: 19-Dec-2023 4:05 PM EST
New treatment reverses Alzheimer’s disease signs, improves memory function
Perelman School of Medicine at the University of Pennsylvania

A “chaperone” molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer’s disease, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

   
Newswise: Common drug for cardiac failure jams a debated blood test for Alzheimer’s disease
Released: 19-Dec-2023 12:05 PM EST
Common drug for cardiac failure jams a debated blood test for Alzheimer’s disease
University of Gothenburg

Alzheimer’s disease (AD) is associated with damaging protein aggregates in the brain, with β-amyloid (Aβ) aggregates called plaques being the key pathology. Entresto (sacubitril/valsartan) is a combined neprilysin inhibitor and angiotensin receptor blocker, approved for the treatment of heart failure.

Newswise: Einstein Receives $10.9 Million Grant to Validate Remote Cognitive Testing for Alzheimer’s and Other Dementias
Released: 18-Dec-2023 9:30 AM EST
Einstein Receives $10.9 Million Grant to Validate Remote Cognitive Testing for Alzheimer’s and Other Dementias
Albert Einstein College of Medicine

Neurologists often diagnose Alzheimer’s disease after evaluating patients during lengthy, in-person office visits.

Newswise: UWF faculty and students develop goggles for early detection of Alzheimer’s Disease
Released: 18-Dec-2023 9:30 AM EST
UWF faculty and students develop goggles for early detection of Alzheimer’s Disease
University of West Florida

University of West Florida faculty and undergraduate students recently developed Pulsed Medical LED goggles for the early detection of Alzheimer’s Disease.

   
Released: 15-Dec-2023 2:05 PM EST
COVID-19 infection alters gene transcription of olfactory mucosal cells in Alzheimer's disease
University of Eastern Finland

A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes.

Released: 14-Dec-2023 1:05 PM EST
Physical and social activities promote healthy brain aging
University of Zurich

Physical exercise is associated with a variety of positive health aspects. Numerous studies have shown that regular physical activity has a preventive effect on cardiovascular diseases, diabetes, cancer, high blood pressure and obesity.

Released: 14-Dec-2023 7:05 AM EST
New study shows exercise can boost brain health
IOS Press

A fascinating link between regular exercise and better brain health has been revealed, according to an international study that included a team of clinical researchers from Pacific Neuroscience Institute’s Brain Health Center, located at Providence Saint John’s Health Center.

Newswise: Virginia Tech researcher probes the potential for preventing and reversing age-related memory loss
Released: 13-Dec-2023 4:05 PM EST
Virginia Tech researcher probes the potential for preventing and reversing age-related memory loss
Virginia Tech

About 40 percent of people over age 65 suffer some form of age-related memory loss, which puts them at higher risk for developing dementia and Alzheimer’s disease.

8-Dec-2023 10:05 AM EST
Very Irregular Sleep Linked to Higher Risk of Dementia
American Academy of Neurology (AAN)

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 12-Dec-2023 11:05 AM EST
How Caregivers of People With Dementia Can Navigate Holidays
Rutgers University-New Brunswick

A Rutgers elder care expert discusses how families can make the most of the season when caring for someone experiencing memory loss

Released: 11-Dec-2023 5:05 PM EST
Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
Picower Institute for Learning and Memory at MIT

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer’s disease (AD) therapy.

Released: 11-Dec-2023 2:05 PM EST
Clues to preventing Alzheimer’s come from patient who, despite genetics, evaded disease
Washington University in St. Louis

A woman who never developed Alzheimer's despite a strong genetic predisposition may hold the key to stopping the disease in its tracks.

Released: 9-Dec-2023 10:05 AM EST
Structure of a central component of the human immune system revealed
Ludwig-Maximilians-Universität München (Munich)

An international team of researchers from LMU and the Helmholtz Centre for Infection Research has visualized the structure of the so-called ASC speck.

Released: 7-Dec-2023 2:15 PM EST
Looking for unique stories about the winter holidays? Check out the Winter Holidays channel
Newswise

It's the moooost wonderful time...of the year! Are you looking for new story ideas that are focused on the winter holiday season? Perhaps you're working on a story on on managing stress and anxiety? Perhaps you're working on a story on seasonal affective disorder? Or perhaps your editor asked you to write a story on tracking Santa? Look no further. Check out the Winter Holidays channel.

       
Newswise: Study Suggests Serotonin Loss May Contribute to Cognitive Decline in the Early Stages of Alzheimer’s Disease
Released: 7-Dec-2023 11:00 AM EST
Study Suggests Serotonin Loss May Contribute to Cognitive Decline in the Early Stages of Alzheimer’s Disease
Johns Hopkins Medicine

Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease.

Released: 6-Dec-2023 12:05 PM EST
New Research in the Treatment of Parkinson's Disease
Gladiator Therapeutics

Researchers at the University of Central Florida College of Medicine (UCF COM) in Orlando, Florida completed research that is very promising in the treatment of Parkinson's disease

Released: 6-Dec-2023 11:05 AM EST
Common dementia drugs not associated with increased risk of falling, but increased chances of fainting
McMaster University

Researchers from McMaster University have found that cholinesterase inhibitors, a type of common medication used to treat dementia, are not associated with an increased risk of falling. However, they found that the medication increased the risk of syncope, or fainting.

Newswise: Diet has a major impact on risk of Alzheimer’s disease
Released: 4-Dec-2023 6:05 PM EST
Diet has a major impact on risk of Alzheimer’s disease
IOS Press

In a detailed study, Diet’s Role in Modifying Risk of Alzheimer’s Disease: History and Present Understanding published in the Journal of Alzheimer’s Disease, we can finally see which diets are helpful in reducing the risk of developing Alzheimer’s disease.

Newswise: IU researchers develop new brain network modeling tools to advance Alzheimer's disease research
Released: 1-Dec-2023 7:20 AM EST
IU researchers develop new brain network modeling tools to advance Alzheimer's disease research
Indiana University

Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools previously developed to analyze brains of patients in the clinic to investigate Alzheimer's disease progression in preclinical animal models.

Released: 28-Nov-2023 6:05 PM EST
Personal wealth is associated with health care costs in people with Alzheimer’s disease
University of Eastern Finland

Finland has a strong public health care system; nevertheless, personal wealth is associated with the costs of hospital care and medication in people with Alzheimer’s disease.

Newswise: Third-year McGovern Medical School student assists in game-changing Alzheimer’s disease discoveries
Released: 28-Nov-2023 11:05 AM EST
Third-year McGovern Medical School student assists in game-changing Alzheimer’s disease discoveries
University of Texas Health Science Center at Houston

Though still a third-year student with McGovern Medical School at UTHealth Houston, Gabriela Grangeiro Cruz is already working to broaden the medical field’s, and the public’s, understanding of Alzheimer’s disease by studying ways to prevent the neurocognitive disorder, which affects 6 million people living in the U.S.

Released: 26-Nov-2023 8:00 AM EST
Pioneering early-onset Alzheimer’s disease study is focus of Alzheimer's & Dementia special issue
Indiana University

A pioneering Alzheimer’s disease study led by Indiana University School of Medicine researchers is the focus of a special issue of Alzheimer’s & Dementia, the journal of the Alzheimer’s Association.

21-Nov-2023 3:05 PM EST
Eating More Whole Grains Is Associated With Less Memory Decline in African Americans
RUSH

Consuming a few servings of whole grains each day may reduce the risk of cognitive decline among older African Americans, according to RUSH researchers.

16-Nov-2023 11:05 AM EST
Adding a Few Servings of Whole Grains Linked to Slower Memory Decline in Black People
American Academy of Neurology (AAN)

Black people who eat more foods with whole grains, including some breads and cereals, quinoa, and popcorn, may have a slower rate of memory decline compared to Black people who eat fewer whole grain foods, according to a study published in the November 22, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The researchers did not see a similar trend in white participants.

Released: 21-Nov-2023 3:45 PM EST
It's not over until it's over. Keep up with the latest COVID research in the Coronavirus channel.
Newswise

Stay informed! Keep up with the latest research on the COVID-19 virus in the Coronavirus channel on Newswise.

Released: 21-Nov-2023 12:00 PM EST
Hearing Loss is Associated with Subtle Changes in the Brain
University of California San Diego

A team of UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science along with Kaiser Permanente Washington Health Research Institute researchers employed hearing tests and magnetic resonance imaging (MRI) to determine whether hearing impairment is associated with differences in specific brain regions and affects dementia risk.

Newswise: Cleveland Clinic Research Finds Sex Differences in  Immune Response and Metabolism Drive Alzheimer’s Disease
Released: 21-Nov-2023 11:05 AM EST
Cleveland Clinic Research Finds Sex Differences in Immune Response and Metabolism Drive Alzheimer’s Disease
Cleveland Clinic

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer’s and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women’s increased risk for the disease and its severity.

Released: 21-Nov-2023 10:05 AM EST
SLU Researcher Finds Help for Alzheimer’s-Associated Agitation with New FDA-Approved Treatment
Saint Louis University

George T. Grossberg, M.D., and colleagues were instrumental in developing the first and only Food and Drug Administration (FDA) approved treatment for agitation associated with Alzheimer's dementia.

Newswise: Coffee Grounds May Hold Key to Preventing Neurodegenerative Diseases
20-Nov-2023 3:40 PM EST
Coffee Grounds May Hold Key to Preventing Neurodegenerative Diseases
University of Texas at El Paso

A team of researchers from The University of Texas at El Paso found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.

Released: 17-Nov-2023 11:05 AM EST
Scientists produce human norepinephrine neurons from stem cells, with significant implications for researching diseases like Alzheimer’s and Parkinson’s
University of Wisconsin–Madison

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer’s and Parkinson’s diseases and used the discovery to grow the neurons from stem cells for the first time.

Released: 16-Nov-2023 10:05 AM EST
How a mutation in microglia elevates Alzheimer’s risk
Picower Institute for Learning and Memory at MIT

A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways

Newswise: McWilliams School of Biomedical Informatics researchers awarded $31M in grants for medical artificial intelligence innovation research
Released: 15-Nov-2023 5:05 PM EST
McWilliams School of Biomedical Informatics researchers awarded $31M in grants for medical artificial intelligence innovation research
University of Texas Health Science Center at Houston

McWilliams School of Biomedical Informatics at UTHealth Houston reached a funding landmark with 15 faculty members awarded 16 different grants totaling more than $31 million between August and October 2023. Each grant has a focus on medical artificial intelligence (AI) innovations and advancements in research or health care.

9-Nov-2023 10:05 AM EST
Smaller Hippocampus Linked to Cognitive Decline
American Academy of Neurology (AAN)

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer’s disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer’s disease or another neurodegenerative disorder. A new study published in the November 15, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology, shows that shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don’t have amyloid plaques in the brain. The hippocampus plays a role in memory.

Newswise: UTHealth Houston researcher receives NIH subcontract to study effects of integrated palliative care on Parkinson’s, related dementia
Released: 15-Nov-2023 3:05 PM EST
UTHealth Houston researcher receives NIH subcontract to study effects of integrated palliative care on Parkinson’s, related dementia
University of Texas Health Science Center at Houston

As part of a five-year, $3.9 million grant from the National Institutes of Health, Adriana Pérez, PhD, professor in the Department of Biostatistics and Data Science with UTHealth Houston School of Public Health in Austin, received a $1.9 million subcontract to determine the scope and drivers of low-value and unequal care for patients with Parkinson’s disease and Parkinson’s disease dementia.

Newswise: The Medical Minute: Alzheimer’s disease basics, what you can do to prevent it
Released: 15-Nov-2023 12:05 PM EST
The Medical Minute: Alzheimer’s disease basics, what you can do to prevent it
Penn State Health

Alzheimer’s disease slowly erases memories and cognitive abilities, upending families ― and it’s incurable. But there are steps you can take to slow and prevent it, says a Penn State Health expert.

Newswise: How good can overpower evil in the genetic determination of Alzheimer’s disease
Released: 13-Nov-2023 7:05 PM EST
How good can overpower evil in the genetic determination of Alzheimer’s disease
Gladstone Institutes

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the “Christchurch mutation” can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer’s disease.

Newswise: This wireless, handheld, non-invasive device detects Alzheimer’s and Parkinson’s biomarkers
9-Nov-2023 7:05 AM EST
This wireless, handheld, non-invasive device detects Alzheimer’s and Parkinson’s biomarkers
University of California San Diego

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly to a laptop or smartphone.

Newswise: Obesity linked to neurodegeneration through insulin resistance
31-Oct-2023 5:05 PM EDT
Obesity linked to neurodegeneration through insulin resistance
PLOS

Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer’s disease.

Released: 6-Nov-2023 12:05 PM EST
High biological age may increase the risk of dementia and stroke
Karolinska Institute

People who have a higher biological age than their actual chronological age have an increased risk of stroke and dementia. The findings suggest that by slowing down the body's aging processes, it may be possible to reduce or delay the onset of disease.

Newswise: How Air Pollution Accelerates Alzheimer’s Disease
Released: 3-Nov-2023 7:05 PM EDT
How Air Pollution Accelerates Alzheimer’s Disease
Cedars-Sinai

Investigators from the Department of Neurosurgery at Cedars-Sinai have determined that exposure to polluted air could accelerate development of Alzheimer’s disease in those with genetic risk factors for the neurodegenerative condition.

Newswise: Mount Sinai Researchers Detail Mechanism of a Key Protein Implicated in Age-Related Brain Dysfunction
Released: 2-Nov-2023 4:35 PM EDT
Mount Sinai Researchers Detail Mechanism of a Key Protein Implicated in Age-Related Brain Dysfunction
Mount Sinai Health System

Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.



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