A new paper looks at how MRI and a clear understanding of the functional anatomy around the prostate can allow radiation oncologists to plan a course of treatment for patients with prostate cancer that spares these critical structures.
Every hospital’s ICU has treated them – the critically ill patients who spend weeks going from crisis to crisis, never quite getting better enough to get out of the ICU, but never quite dying. Now, research shows they really are a different kind of patient.
Compared to the nicotine patch and a placebo, the smoking cessation aids varenicline (marketed as Chantix in the U.S.) and bupropion (Zyban) do not show a significant increase in neuropsychiatric adverse events, reports an international team of researchers in a study published online April 22 in the journal The Lancet.
George Washington University's Dr. Michael S. Irwig published a review article in The Lancet Diabetes & Endocrinology journal on testosterone therapy for transgender men, calling for more research.
By spending less than $5 per person on essential health care services such as contraception, medication for serious illnesses and nutritional supplements, millions of maternal and child lives could be saved every year, according to a new analysis led by the Johns Hopkins Bloomberg School of Public Health.
Since 1980, the number of adults with diabetes worldwide has quadrupled from 108 million to 422 million in 2014, according to a new study published in The Lancet. The findings provide the most comprehensive estimates of worldwide diabetes trends to date and show that diabetes is fast becoming a major problem in low and middle income countries.
An investigational stem cell therapy derived from patients’ own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.
More walkable neighborhoods, parks and public transit could all reduce your chance of becoming one of the 600 million adults who battle obesity worldwide, according to researchers at University of California, San Diego School of Medicine. The study, recently published online in The Lancet, found a neighborhood’s design plays a critical role in physical activity and could help reduce non-communicable diseases, such as obesity, diabetes and cardiovascular disease.
End-stage heart failure patients treated with stem cells harvested from their own bone marrow experienced 37 percent fewer cardiac events - including deaths and heart failure hospital admissions - than a placebo-controlled group, according to a new study. Results from ixCELL-DCM, the largest cell therapy clinical trial for treating heart failure to date, will be presented at the 2016 American College of Cardiology annual meeting and published online in The Lancet on April 4.
A landmark study published this month in the leading medical journal, The Lancet, reports the discovery of a blood test that can predict whether someone is likely to develop tuberculosis (TB) disease, long before the disease manifests.
A new study examines fertility issues in male and female childhood cancer survivors who had received chemotherapy. The study found that while most female survivors still have a good chance of conceiving, male survivors are significantly less likely to father children.
Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study led by a Duke Cancer Institute researcher.
The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution. However, for the first time, findings from a large, randomized clinical trial show that this aggressive approach does not save more lives, researchers from Penn Medicine and other institutions report in The Lancet.
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in people with advanced HIV/AIDS infections. Those with HIV and AIDS are highly susceptible to TB.
Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.
An imbalance of certain gut microbes appears to be the underlying cause of a frequently fatal intestinal illness in premature babies, according to new research led by Washington University School of Medicine in St. Louis.
Vitamin D supplementation during pregnancy may lead to stronger bones in babies born during the winter months, a new Southampton study has shown.
Researchers seeking to better understand how our genes contribute to stroke risk have completed what is believed to be the largest and most comprehensive review of the human genome to identify genes that predispose people to ischemic stroke, the cause of approximately 85 percent of all strokes.
Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed. Moffitt Cancer Center researchers are leading the way in the creation of novel therapies. Most recently, Moffitt, in conjunction with partner institutions, initiated a multicenter phase 1b clinical trial to determine the safety and efficacy of a new drug combination for non-small cell lung cancer that stimulates a patient’s immune system to target and kill cancer cells.
Vascular surgery appears to be safer than stenting for patients over 70 years of age with carotid stenosis, or a blockage of the carotid arteries in the neck, according to new findings published in the Lancet.
A new study led by Michael Privitera, MD, professor of the Department of Neurology and director of the Epilepsy Center at the University of Cincinnati Neuroscience Institute, tested two generic lamotrigine (prescription antiepileptic) products and found no detectable difference in clinical effects among patients in the trial. The findings were published this week in an advance online edition of The Lancet Neurology.
Mayo Clinic researchers, in collaboration with the Centers for Disease Control and Prevention (CDC) and health officials from Minnesota, North Dakota and Wisconsin, have discovered a new bacterial species that causes Lyme disease in people. The new species has been provisionally named Borrelia mayonii. Prior to this finding, the only species believed to cause Lyme disease in North America was Borrelia burgdorferi.
Preliminary findings published in The Lancet, one of the world’s most prestigious journals
Black-box warnings about the dangers of attention-deficit hyperactivity disorder (ADHD) medications are confusing and could have serious consequences for the risk of youth suicide, according to researchers at the Institut universitaire en santé mentale de Montréal (CIUSSS de l'Est-de-l'Île-de-Montréal) and the University of Montreal.
Electronic cigarettes are widely promoted and used to help smokers quit traditional cigarettes, but a new analysis from UC San Francisco found that adult smokers who use e-cigarettes are actually 28 percent less likely to stop smoking cigarettes.
Children and young adults with severe forms of epilepsy that does not respond to standard antiepileptic drugs have fewer seizures when treated with purified cannabinoid, according to a multi-center study led by researchers from UCSF Benioff Children’s Hospital San Francisco.
In a world first, clinical researchers from the Universities of Manchester and Liverpool have collaborated with colleagues in south Asia to adapt a parent-led autism therapy and successfully tested it in India and Pakistan, with the aim of improving treatment for an estimated 5 million children in the region with the disorder.
Genetic variation in patients with inflammatory bowel disease (IBD) appears to play a major role in determining how sick they will become and could provide a road map for more effective treatments.
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