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    17-Oct-2018 1:00 PM EDT

Article ID: 702175

Vast Leukemia Dataset Could Help Researchers Match Therapies to Patients

Howard Hughes Medical Institute (HHMI)

Data on the molecular makeup and drug sensitivity of hundreds of patient samples could accelerate progress against the aggressive blood cancer acute myeloid leukemia.

15-Oct-2018 10:05 AM EDT

Article ID: 702353

St. Jude Researcher Receives Share of $86 Million in NIH Funding

St. Jude Children's Research Hospital

Shengdar Tsai, Ph.D., an assistant member of the Department of Hematology at St. Jude Children’s Research Hospital, has received a five-year $3 million grant from the National Institutes of Health’s Common Fund for his work on genome editing safety.

17-Oct-2018 12:05 PM EDT

Article ID: 702338

Researcher Wins Breakthrough Prize for Innate Immunity Discovery

UT Southwestern Medical Center

UT Southwestern biochemist Dr. Zhijian “James” Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body’s immune defense against infections and cancers. That enzyme patrols the cell’s interior and triggers the immune system in response to DNA.

17-Oct-2018 10:05 AM EDT

Article ID: 702320

Researchers Develop, Test New System for Making Biorenewable Chemicals

Iowa State University

The U.S. Department of Energy is supporting development of a system for producing biobased chemicals that's based on the idea of "bioprivileged molecules." Researchers at the Center for Biorenewable Chemicals based at Iowa State University say such molecules have new and valuable properties.

16-Oct-2018 4:55 PM EDT

Article ID: 702311

Alligators Shed Light on Reproductive Disorders

University of Georgia

Researchers from the University of Georgia have discovered that timing of exposure is a key factor in how certain contaminants affect the reproductive system—information that may help scientists understand the causes of reproductive disorders in wildlife and women.

16-Oct-2018 3:05 PM EDT

Article ID: 702276

A Human Brain Model in a Petri Dish?

Case Western Reserve University

Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids. But the ethics to help guide researchers and regulators lag behind the technological capability to “grow” brains in a petri dish. That is about to change as a group of bioethicists and scientists chart the unexplored territory of neuroethics, which is quickly emerging from the ability to bioengineer models of the brain. The study, called “The Brainstorm Project,” will be led by Insoo Hyun, PhD, professor of bioethics at Case Western Reserve University School of Medicine.

16-Oct-2018 10:05 AM EDT

Article ID: 702270

Mapping Genetic Differences in Breast Cancer Can Improve Care for Underserved Populations

University of Chicago Medical Center

A new study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that aggressive molecular features were far more prevalent in tumors from women of African ancestry than women of European ancestry. Those differences could explain disparities in breast cancer mortality for black women across the African Diaspora and hasten a shift to precisely targeted therapies.

16-Oct-2018 10:00 AM EDT

Article ID: 702201

ISPOR Publishes New Report on the Application of Constrained Optimization Methods in Healthcare

ISPOR—The Professional Society for Health Economics and Outcomes Research

ISPOR—the professional society for health economics and outcomes research (HEOR), has published a new Good Practices for Outcomes Research Report that illustrates how constrained optimization methods can be used to assess the value of health technologies.

16-Oct-2018 7:35 AM EDT

Article ID: 702255

How Communication Among Cells Affects Development of Multicellular Tissue

Georgia Institute of Technology

Using a combination of computational modeling and experimental techniques, a research team has developed new information about how intercellular communication affects the differentiation of an embryonic stem cell colony over time.

15-Oct-2018 5:05 PM EDT

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