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Article ID: 708137

This Immune Cell Function Could Control Deadly Allergic Reactions

Michigan State University

Michigan State University scientists have identified a master control mechanism on mast cells, a type of immune cell, that can prevent the immune system from overreacting in times of stress, potentially limiting, or even stopping allergic reactions from happening.

14-Feb-2019 4:05 PM EST
Newswise: Asthma Controller Step Down Yardstick - Treatment Guidance for When Asthma Improves

Article ID: 707080

Asthma Controller Step Down Yardstick - Treatment Guidance for When Asthma Improves

American College of Allergy, Asthma and Immunology (ACAAI)

The focus for asthma treatment is often stepping up treatment, but clinicians need to know how to step down therapy when symptoms improve.

25-Jan-2019 11:05 AM EST

Article ID: 706914

Study Finds Unique Form of Chronic Sinusitis in Older Patients

Vanderbilt University Medical Center

Older patients with a diagnosis of chronic sinusitis — a disease of the nasal cavity and paranasal sinuses that often persists over many years — have a unique inflammatory signature that may render them less responsive to steroid treatment, according to a new study published by Vanderbilt researchers.

23-Jan-2019 10:00 AM EST

Article ID: 706516

Fever alters immune cells so they can better reach infections

Cell Press

Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how. They found in mice that fever alters surface proteins on immune cells like lymphocytes to make them better able to travel via blood vessels to reach the site of infection. Their work appears on January 15 in the journal Immunity.

15-Jan-2019 12:50 PM EST

Article ID: 706514

JAMA report outlines recommendations for evaluation and management of penicillin allergy

Massachusetts General Hospital

While more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that more 95 percent actually can be treated safely with this class of antibiotics, improving treatment outcomes and reducing the risk of infection with dangerous resistant pathogens such as Clostridium difficile (C. difficile). A review article in the January 15 issue of JAMA recommends best practices for evaluation of reported penicillin allergies and provides clinicians with guidance and tools to help determine appropriate procedures based on the severity of previously reported reactions.

15-Jan-2019 12:40 PM EST
Newswise: Engineered T cells promote long-term organ transplant acceptance

Article ID: 706512

Engineered T cells promote long-term organ transplant acceptance

University of Basel

Organ transplant rejection is a major problem in transplantation medicine. Suppressing the immune system to prevent organ rejection, however, opens the door to life-threatening infections. Researchers at the University of Basel's Biozentrum have now discovered a molecular approach preventing rejection of the transplanted graft while simultaneously maintaining the ability to fight against infections.

15-Jan-2019 12:30 PM EST
Newswise: Intestinal Bacteria From Healthy Infants Prevent Food Allergy
  • Embargo expired:
    14-Jan-2019 11:00 AM EST

Article ID: 706227

Intestinal Bacteria From Healthy Infants Prevent Food Allergy

University of Chicago Medical Center

New research from the University of Chicago shows that healthy infants have intestinal bacteria that prevent the development of food allergies.

9-Jan-2019 2:05 PM EST

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