Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.
Cecilia Lindestam Arlehamn, Ph.D., aims to shed light on how sex-based immune system differences may affect the development and progression of these neurodegenerative diseases in men versus women.
Higher exposure to a certain type of traffic-related air pollution called particulate matter may be linked to an increased risk of dementia, according to a meta-analysis published in the October 26, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers specifically looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air. The meta-analysis included all available studies on air pollution and risk of dementia.
The Presidential Symposium at the ongoing American Neurological Association 147th Annual Meeting outlined major risks to neurological health from environmental exposures to pesticides, air pollution, synthetic materials, and more — now emerging as a major research area in neuroscience.
As the American Neurological Association’s 147th Annual Meeting wraps up today, October 25, the ANA is holding a Media Roundtable at 11 a.m. U.S. Central for reporters to access the latest developments in neurology and neuroscience.
The early-stage research tested the delivery and safety of the new implantable catheter design in two sheep to determine its potential for use in diagnosing and treating diseases in the brain.
The latest articles that have been added to the Environmental Health channel.
People who gain or lose weight soon after being diagnosed with Parkinson’s disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a study published in the October 19, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Rutgers study examines gene regulation and nerve cell death in male and female brains.
The Presidential Symposium at the American Neurological Association’s 2022 Annual Meeting (ANA2022) in Chicago will shine a spotlight on the role of environmental exposures — air pollution, pesticides, microplastics, and more — in diseases like dementias and developmental disorders.
Abstracts of breaking research in neurology and neuroscience, to be presented at the 2022 American Neurological Association Annual Meeting Oct. 22-25, are now available in Annals of Neurology and on the ANA2022 website.
Work aims to identify neuroprotective strategies that will help treat this progressive, debilitating disorder
By using artificial intelligence, Houston Methodist researchers are able to predict hospitalization outcomes of geriatric patients with dementia on the first or second day of hospital admission. This early assessment of outcomes means more timely interventions, better care coordination, more judicious resource allocation, focused care management and timely treatment for these more vulnerable, high-risk patients. The study is available online in Alzheimer’s & Dementia: Translational Research and Clinical Interventions, a journal of the Alzheimer’s Association.
New study identifies how oxidative breaks form and are repaired in what scientists thought to be ‘junk’ DNA
The National Institutes of Health (NIH) awarded a $10.7 million five-year renewal grant to Cleveland Clinic to expand a national research consortium focused on improving the diagnosis and treatments for Dementia with Lewy Bodies. The Dementia with Lewy Bodies Consortium, established in 2017, centralized research efforts and created a national, coordinated registry for clinical data.
Parkinson’s disease is the fastest-growing neurodegenerative disease, now affecting more than 10 million people worldwide, yet clinicians still face huge challenges in tracking its severity and progression.
Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson’s disease and halts movement problems in mice.
The latest research and expert commentary on pain management.
吞咽时如果食物或饮料意外地进入错误部位，就会产生不适感，许多人都有过这种经历。但吞咽问题有时会成为慢性问题，并可能是某种应该予以治疗的疾病的征兆。妙佑伦敦医疗中心的胃肠科医生James East医学博士解释了为什么会发生吞咽困难以及如何解决这个问题。
يعاني الكثير من الناس من الانزعاج بسبب انتقال الطعام أو المشروبات دون قصد إلى المكان الخطأ عند البلع، لكن مشاكل البلع تصبح أحيانًا مزمنة وقد تكون علامة لحالة صحية يجب علاجها. يبيّن جيمس إيست، دكتور الطب، طبيب الجهاز الهضمي في مايو كلينك للرعاية الصحية في لندن، سبب صعوبة البلع لدى الأشخاص وكيفية علاج هذه المشكلة.
Muitas pessoas já experimentaram o desconforto de ter alimentos ou bebidas descendo acidentalmente pelo lugar errado ao engolir. Entretanto, problemas para engolir muitas vezes se tornam crônicos e podem ser um sinal de alguma doença que precisa ser tratada.
The latest research on plants brought to you by Newswise.
Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson’s disease, ultimately causing nerve cell death.
Muchas personas experimentan la incomodad de que un alimento o bebida se vaya accidentalmente por el lugar equivocado durante la deglución. Sin embargo, los problemas de deglución a veces se vuelven crónicos y pueden ser la señal de una enfermedad que debería tratarse.
Inactivation of a particular protein complex that plays a key role in keeping genes switched off leads to nerve cells not producing enough essential neurotransmitters.
Many people have experienced the discomfort of food or a beverage accidentally going to the wrong place when swallowing. But swallowing issues sometimes become chronic and may be a sign of a health condition that should be treated.
The latest research and expert commentary on the monkeypox outbreak.
Regular treadmill exercise helped improve Parkinson’s disease symptoms in mice in a recent study by researchers at RUSH.
Flexible implanted electronics are a step closer toward clinical applications thanks to a recent breakthrough technology developed by a research team from Griffith University and UNSW Sydney.
We all know that people have reported brain fog and other neurological issues after having COVID-19. But a new study shows some sobering news – COVID-19 infections may have serious long-term effects. Major findings include that COVID-19 infections may predispose individuals to developing irreversible neurological conditions that may increase the likelihood of strokes and the chance of developing persistent brain lesions that can lead to brain bleeding. The findings appear online in press in the journal Ageing Research Reviews.
JMIR Publications recently published "Benefits of Virtual Reality Balance Training for Patients With Parkinson Disease: Systematic Review, Meta-analysis, and Meta-Regression of a Randomized Controlled Trial" in JMIR Serious Games, which reported that virtual reality (VR) balance training is increasingly being pursued in biomedical research, specifically with respect to investigating balance ability with VR.
UC San Diego researchers report that individuals with two copies of a gene mutation show evidence of substantial iron buildup in regions of the brain, raising risk for movement disorders like Parkinson’s disease.
Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.
Johns Hopkins Medicine researchers have helped develop a nanobody capable of getting through the tough exterior of brain cells and untangling misshapen proteins that lead to Parkinson’s disease, Lewy body dementia, and other neurocognitive disorders caused by the damaging protein.
In their study, the research groups looked at a protein called Creld. A study from Bonn had recently been able to demonstrate that Creld plays an important role in the development of the heart in mammals.
The dementia disorder Alzheimer’s disease has a symptom-free course of 15 to 20 years before the first clinical symptoms emerge.
Neurodegenerative diseases like Alzheimer’s disease or Parkinson’s disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the result of minute deviations in the chemical composition of the biomolecules. Researchers at the Karlsruhe Institute of Technology (KIT) have developed a simple and effective method for detecting such misfolding at an early stage of the disease. Misfolding is revealed by the structure of dried residue from protein and peptide solutions.
Parkinson's is a progressive and debilitating disease of the brain that eventually compromises patients' ability to walk and even to talk. Its diagnosis is complex, and in the early stages – impossible.
Parkinson’s Disease affects 10 million people worldwide and its symptoms include tremors in the fingers and hands, small handwriting, loss of smell, walking difficulties, dizziness, and others.
Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. A team from Empa and the University of Limerick was able to show how the protein takes on an unusual shape when exposed to large amounts of copper ions. The findings could help develop new strategies for the treatment of neurodegenerative diseases.
As one of the countries with a rapidly increasing aging population, especially this 2022, Thailand is now becoming an ‘aging’ society and will likely become a ‘super-aging society’ by 2031. To better meet the needs and provide services to the nation’s aging society, experts from various fields at Chulalongkorn University have conducted research to produce and develop innovations for the elderly.
Here are some of the latest articles that have been added to the Aging channel on Newswise, a free source for journalists.
Researchers have uncovered a new function for alpha-synuclein, a well-known protein marker of Parkinson’s, with relevance toward treatment for the disease
Researchers at Kobe University and Hiroshima University have successfully developed a biomarker that will enable Parkinson’s disease to be rapidly and inexpensively diagnosed from blood serum samples.
A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai
In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson’s disease.
New research finds that the novel coronavirus can make the mouse brain more susceptible to a toxin that induces nerve-cell loss seen in Parkinson’s.
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