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  • Embargo expired:
    27-Oct-2014 6:00 AM EDT

Article ID: 625186

How Cells Know Which Way to Go

Johns Hopkins Medicine

Amoebas aren’t the only cells that crawl: Movement is crucial to development, wound healing and immune response in animals, not to mention cancer metastasis. In two new studies from Johns Hopkins, researchers answer long-standing questions about how complex cells sense the chemical trails that show them where to go — and the role of cells’ internal “skeleton” in responding to those cues.

Released:
26-Oct-2014 6:00 AM EDT

Article ID: 625207

New Compounds Reduce Debilitating Inflammation

Case Western Reserve University

Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation in diseases such as ulcerative colitis and arthritis. The compounds appear to curtail inflammation-triggering signals from RIPK2. These findings appear in the Journal of Biological Chemistry.

Released:
24-Oct-2014 1:00 PM EDT

Article ID: 625199

A New Dent in HIV-1’s Armor

Salk Institute for Biological Studies

Salk scientists identify a promising target for HIV/AIDS treatment

Released:
24-Oct-2014 12:00 PM EDT
  • Embargo expired:
    23-Oct-2014 2:00 PM EDT

Article ID: 624906

New Microscope Collects Dynamic Images of the Molecules That Animate Life

Howard Hughes Medical Institute (HHMI)

A new imaging platform developed by Eric Betzig and colleagues at the Howard Hughes Medical Institute's Janelia Research Campus offers another leap forward for light microscopy. The new technology collects high-resolution images rapidly and minimizes damage to cells, meaning it can image the three-dimensional activity of molecules, cells, and embryos in fine detail over longer periods than was previously possible. Betzig was one of three scientists who shared the 2014 Nobel Prize in Chemistry earlier this month.

Released:
20-Oct-2014 1:05 PM EDT
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  • Embargo expired:
    23-Oct-2014 2:00 PM EDT

Article ID: 625034

Cutting the Ties That Bind

Stowers Institute for Medical Research

The development of a new organism from the joining of two single cells is a carefully orchestrated endeavor. But even before sperm meets egg, an equally elaborate set of choreographed steps must occur to ensure successful sexual reproduction. Those steps, known as reproductive cell division or meiosis, split the original number of chromosomes in half so that offspring will inherit half their genetic material from one parent and half from the other.

Released:
22-Oct-2014 4:00 PM EDT
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  • Embargo expired:
    23-Oct-2014 12:00 PM EDT

Article ID: 624903

Thyroid Cancer Genome Analysis Finds Markers of Aggressive Tumors

Michigan Medicine - University of Michigan

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.

Released:
20-Oct-2014 12:00 PM EDT
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  • Embargo expired:
    23-Oct-2014 12:00 PM EDT

Article ID: 624949

New TSRI Studies Bring Scientists Closer to Combating Dangerous Unstable Proteins

Scripps Research Institute

Scientists at The Scripps Research Institute have discovered a way to decrease deadly protein deposits in the heart, kidney and other organs associated with a group of human diseases called the systemic amyloid diseases.

Released:
21-Oct-2014 10:00 AM EDT
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  • Embargo expired:
    22-Oct-2014 5:00 AM EDT

Article ID: 624927

UNC Scientists Discover Hidden Subpopulation of Melanoma Cells

University of North Carolina Health Care System

UNC researchers discover a subpopulation of melanoma cancer cells in blood vessels of tumors. These cells, which mimic non-cancerous endothelial cells that normally populate blood vessels, could provide researchers with another target for cancer therapies.

Released:
20-Oct-2014 4:30 PM EDT
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  • Embargo expired:
    20-Oct-2014 9:00 AM EDT

Article ID: 624843

Over-Organizing Repair Cells Set the Stage for Fibrosis

The Rockefeller University Press

The excessive activity of repair cells in the early stages of tissue recovery sets the stage for fibrosis by priming the activation of an important growth factor, according to a study in The Journal of Cell Biology.

Released:
17-Oct-2014 10:00 AM EDT
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  • Embargo expired:
    19-Oct-2014 1:00 PM EDT

Article ID: 624836

New Insight That “Mega” Cells Control the Growth of Blood-Producing Cells

Stowers Institute for Medical Research

While megakaryocytes are best known for producing platelets that heal wounds, these “mega” cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research. In fact, hematopoietic stem cells differentiate to generate megakaryocytes in bone marrow. The Stowers study is the first to show that hematopoietic stem cells (the parent cells) can be directly controlled by their own progeny (megakaryocytes).

Released:
17-Oct-2014 12:00 PM EDT

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