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Article ID: 613563

Recycling of 'Chauffeur Protein' Helps Regulate Fat Production

Johns Hopkins Medicine

Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, may help develop drugs to decrease excessive fat production and its associated conditions in people, including fatty liver disease and diabetes.

10-Feb-2014 1:45 PM EST
  • Embargo expired:
    10-Feb-2014 9:00 AM EST

Article ID: 613394

Conserved Nuclear Envelope Protein Uses a Shuttle Service to Travel Between Job Sites

Stowers Institute for Medical Research

Researchers at the Stowers Institute for Medical Research have glimpsed two proteins working together inside living cells to facilitate communication between the cell's nucleus and its exterior compartment, the cytoplasm. The research provides new clues into how a crucial protein that is found in organisms from yeast to humans does its work.

5-Feb-2014 5:00 PM EST
  • Embargo expired:
    6-Feb-2014 2:00 PM EST

Article ID: 613217

The Ultimate Decoy: Scientists Find Protein that Helps Bacteria Misdirect Immune System

Scripps Research Institute

A team led by scientists at The Scripps Research Institute has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target.

3-Feb-2014 12:00 PM EST

Article ID: 613429

Global Regulator of mRNA Editing Found

University of California San Diego Health

An international team of researchers, led by scientists from the University of California, San Diego School of Medicine and Indiana University, have identified a protein that broadly regulates how genetic information transcribed from DNA to messenger RNA (mRNA) is processed and ultimately translated into the myriad of proteins necessary for life.

6-Feb-2014 2:00 PM EST

Article ID: 613433

Toxin from Brain Cells Triggers Neuron Loss in Human ALS Model

Columbia University Irving Medical Center

In most cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, a toxin released by cells that normally nurture neurons in the brain and spinal cord can trigger loss of the nerve cells affected in the disease, Columbia researchers reported today in the online edition of the journal Neuron.

6-Feb-2014 2:00 PM EST

Article ID: 613422

A Key Facilitator of mRNA Editing, Required for Proper Gene Expression, Uncovered by IU Researchers

Indiana University

Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.

6-Feb-2014 12:00 PM EST

Article ID: 613323

Fruit Flies – Fermented-Fruit Connoisseurs – Are Relentless Party Crashers

University of Washington

That fruit fly appearing moments after you poured that first glass of cabernet, has just used a poppy-seed-sized brain to conduct a finely-choreographed search and arrive in time for happy hour.

4-Feb-2014 4:00 PM EST

Article ID: 613289

New Fruitfly Sleep Gene Promotes the Need to Sleep

Perelman School of Medicine at the University of Pennsylvania

All creatures great and small, including fruitflies, need sleep. The timing of when we sleep versus are awake is controlled by cells in tune with circadian rhythms of light and dark. Most of the molecular components of that internal clock have been worked out. On the other hand, what drives how much we sleep is less well understood. Researchers report a new protein involved in the homeostatic regulation of sleep in the fruitfly.

4-Feb-2014 12:30 PM EST

Article ID: 613267

GW Researcher Finds Connection in Pathogenesis of Neurological Diseases, HIV

George Washington University

A new study published in the Journal of Biological Chemistry by George Washington University researcher Michael Bukrinsky, M.D., Ph.D., shows similarities in the pathogenesis of prion disease — misfolded proteins that can lead to neurological diseases — and the HIV virus.

4-Feb-2014 10:00 AM EST

Article ID: 613116

New Weapon Fights Drug-Resistant Tumors

Koch Institute for Integrative Cancer Research at MIT

Biologists from MIT's Koch Institute identify a drug that can help wipe out reservoirs of cancer cells in bone marrow.

31-Jan-2014 11:00 AM EST

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