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  • Embargo expired:
    10-Oct-2018 5:00 PM EDT

Article ID: 701795

Cancer Patients with Rare Deadly Brain Infection Treated Successfully with Off-the-Shelf Adoptive T-Cell Therapy in Clinical Trial

University of Texas M. D. Anderson Cancer Center

An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection sometimes observed in patients with cancer and other diseases in which the immune system is compromised. The study, led by Katy Rezvani, M.D., Ph.D., professor, Department of Stem Cell Transplantation and Cellular Therapy at The University of Texas MD Anderson Cancer Center, showed marked improvement in three PML patients infused with donor T cells targeting the BK virus. Findings were published in the Oct. 11 online issue of the New England Journal of Medicine.

Released:
9-Oct-2018 5:00 PM EDT
  • Embargo expired:
    10-Oct-2018 5:00 AM EDT

Article ID: 701804

Mayo Clinic researchers identify gene types driving racial disparities in myeloma

Mayo Clinic

ROCHESTER Minn. — Researchers at Mayo Clinic have identified three specific gene types that account for a known two-to-three-fold increase in myeloma diagnoses among African-Americans. Researchers also demonstrated the ability to study race and racial admixture more accurately using DNA analysis. The findings were published today in Blood Cancer Journal.

Released:
8-Oct-2018 3:00 PM EDT
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Article ID: 701913

NIH awards WVU $11.2 million for interdisciplinary cancer research

West Virginia University

West Virginia University’s School of Pharmacy will soon become one of the few pharmacy schools in the nation that leads a center of biomedical research excellence.

Released:
9-Oct-2018 2:05 PM EDT
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Article ID: 701891

Crosstalk between fallopian tube, ovary may drive the spread of ovarian cancer

University of Illinois at Chicago

New research shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine from the ovary, causing cancer cells to migrate.

Released:
9-Oct-2018 11:05 AM EDT
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Article ID: 701887

New Options for Breast Cancer Drug Development Found in Estrogen Receptors

Case Western Reserve University

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Now, researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor that could serve as a valuable new drug target. In Nature Communications, researchers describe a “burning the bridge” strategy to disrupting the estrogen receptor, and how to screen breast cancer drugs designed to do it.

Released:
9-Oct-2018 10:05 AM EDT
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Article ID: 701869

Researchers linking Clean Air Act to soil composition

West Virginia University - Eberly College of Arts and Sciences

A team of West Virginia University researchers are investigating the impact of the Clean Air Act on soil and tree growth in the eastern U.S.

Released:
9-Oct-2018 8:05 AM EDT
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Article ID: 701851

New Study Shows Promise for Targeting Breast Cancer Metastasis

University of Kentucky

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as collagen XIII could be key for suppressing breast cancer metastasis.

Released:
8-Oct-2018 4:40 PM EDT
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Article ID: 701849

What inspired Mendel?

Genetics Society of America

Newly uncovered newspaper articles shed light on Mendel’s motivations.

Released:
8-Oct-2018 4:30 PM EDT

Article ID: 701847

Reversing Paralysis: Stem Cell Therapy Aims to Repair Spinal Cords Afflicted by Rare Disorder

UT Southwestern Medical Center

By injecting patients with stem cells engineered to repair the central nervous system – called progenitor cells – UT Southwestern scientists are working to establish the first treatment that can repair spinal cords inflamed by transverse myelitis.

Released:
8-Oct-2018 4:05 PM EDT

Article ID: 701848

Recovering From a Heart Attack? Hold the Antibiotics

University of Wisconsin-Madison

An international team of researchers has shown in mice that a healthy gut microbiome is important for recovery after a heart attack.

Released:
8-Oct-2018 4:05 PM EDT

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