One of the biggest goals of immunotherapy is to reverse T cell exhaustion to boost the immune system’s ability to destroy cancerous cells. Researchers at Sanford Burnham Prebys studying melanoma have found a new way to make this happen.
For millions of Americans that suffer from seasonal allergies (pollen and mold), climate change is exacerbating an earlier, longer, and overall worse allergy season.
The 184th ASA Meeting will include three press conferences on Tuesday, May 9. The in-person presentations will also be livestreamed and recorded. Topics will focus on a wide range of newsworthy sessions, including 3D-printing head simulators, tracking immune cells with ultrasound, investigating the impact of skin color on breast cancer diagnosis, mimicking insects to create miniature microphones, and locating leaks in water networks. Reporters can register for in-person or virtual attendance.
In a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies.
As an African American female, Ilia Smith didn’t think she would get melanoma. However, after years of tanning and being outdoors, her life changed drastically when she was diagnosed with stage 2 melanoma. While Ilia makes sure she protects herself from the sun now, her attitudes about skin cancer early on are similar to the attitudes and behaviors of many Americans.
Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.
According to a new Finnish study, greenness around the home in early childhood does not seem to protect children from atopic eczema. Instead, the proximity of coniferous, mixed forests and agricultural areas was associated with elevated risk of eczema. The effect was seen especially in children who were born in the spring.
While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin. A UT Southwestern physician who specializes in rheumatology says it’s essential to know what to look for.
In its Recommendation Statement on Screening for Skin Cancer, the U.S. Preventive Services Task Force — a group that provides guidance for primary care physicians — has determined that there is not enough scientific evidence to make a recommendation about adults receiving skin cancer screenings from their primary care doctor.
Accure Acne, Inc.™ (www.accureacne.com), a pioneer in the development of innovative solutions for the treatment of acne, announced today that Alfred (Al) Intintoli has joined the company as Chief Technology Officer.
Cedars-Sinai Cancer oncologists and researchers are available to comment on late-breaking topics and research throughout the American Association for Cancer Research (AACR) Annual Meeting 2023, happening April 14-19 in Orlando.
Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.
Human skin cells provided by Marjana Tomic-Canic, Ph.D., director of the Wound Healing and Regenerative Medicine Research Program at the University of Miami Miller School of Medicine, were launched to the International Space Station for advanced testing as part of a research voyage by CUTISS, a Swiss life sciences company.
Golden State Dermatology (GSD) is pleased to announce a new partnership with the dermatology practice of Christopher M. Barnard, MD located in Carmel-by-the-Sea, Calif. The new partnership expands the GSD footprint to include 27 locations across the San Francisco Bay Area, Central Coast, and California's Central Valley and Sacramento Valley.
The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai will expand its research training program in skin biology with support from a five-year, $1.3 million T32 grant from the National Institutes of Health (NIH) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
Institutional Research Grants provide important financial support for new treatments and discovering valuable genetic information. This year’s grants fund the development of a new skin cancer detection and treatment device, as well as studies that analyze the relationship between cancer treatment and mental health, how cells detect and repair broken DNA, how metabolism affects cancer cells, and the possible link between leukemia, inflammation, and aging.
A novel approach to administer intrathecal (IT) immunotherapy (directly into the spinal fluid) and intravenous (IV) immunotherapy was safe and improved survival in a subset of patients with leptomeningeal disease (LMD) from metastatic melanoma, according to interim analyses of a Phase I/Ib trial led by researchers at The University of Texas MD Anderson Cancer Center.
The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
New, unusual-looking growths or changing spots on your skin are important indicators that it is time to see a dermatologist, says Sofia Chaudhry, M.D., associate professor of dermatology at Saint Louis University’s School of Medicine.
Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy. Moffitt Cancer Center researchers are looking at new targets to help inhibit tumor development and promote antitumor immunity, one being the STING signaling pathway. In a new article published in Nature Communications, a team of Moffitt and University of Miami Miller School of Medicine investigators demonstrate that targeting the STING pathway with a combination strategy results in improved antitumor activity.
Needles are an uncomfortable but necessary aspect of vaccination. But today, scientists report steps toward an alternative, relatively painless method that can deliver biological materials to cells by “shooting” them in with air. They will present their results at ACS Spring 2023.
Skin issues can have a serious impact on your health and well-being. For the 7.5 million Americans1 living with psoriasis, itch can be the most bothersome part of their condition because it can make it difficult to sleep and hard to concentrate, as well as affect other aspects of their quality of life.
Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis.
Cedars-Sinai Cancer experts in the fields of pancreatic, gastrointestinal, skin and breast surgical oncology are available to share research findings and comment on the latest news coming out of the Society of Surgical Oncology 2023 International Conference on Surgical Cancer Care March 22-25 in Boston.
An advanced surgical therapy has proved considerably more efficacious than conventional treatments for patients with melanoma in the eye (uveal) that has spread to the liver, a University of Gothenburg study shows.
Staphylococcus aureus, Clostridioides difficile, Candida auris, Drug-resistant Shigella. These bacteria not only have difficult names to pronounce, but they are also difficult to fight off. These bacteria may infect humans and animals, and the infections they cause are harder to treat than those caused by non-resistant bacteria. Antimicrobial resistance is an urgent global public health threat.
Staphylococcus aureus. You may have had it in connection with a wound infection. In most cases, it will pass without treatment, while severe cases may require antibiotics, which kills the bacteria. This is the case for the majority of the population. In fact, many of us – though we feel perfectly fine – carry staphylococci in the nose, a good, moist environment in which the bacteria thrive.
Three new officers and four new board members will be installed immediately upon conclusion of the 2023 Annual Meeting of the American Academy of Dermatology, the world’s largest dermatologic society.
Board-certified dermatologist Terrence A. Cronin Jr., MD, FAAD, will begin his one-year term as president of the American Academy of Dermatology at the close of the Academy’s Annual Meeting. Dr. Cronin will lead the world’s largest dermatologic society that represents more than 20,800 physicians who specialize in diagnosis and treatment of skin, hair, and nail conditions.
Millions of people in the U.S. report having a metal allergy, and current estimates state that 10 percent of Americans will receive a medical implant during their lifetime.
Hair loss in women can be emotionally devastating and may negatively impact quality of life, and new research suggests that it can also be associated with having other common medical conditions.
New research shows that as wildfires are increasing in frequency, intensity and extent, and affecting air quality across the U.S., they are having a detrimental effect on people with and without skin conditions.
Psoriasis and eczema affect men and women differently, with women needing to take extra precautions when considering treatments if they’re planning for pregnancy.
A patient presenting with painful, swirling skin lesions, chills, and weight loss was found to be suffering from erythema gyratum repens (EGR), a rare and striking skin condition that is associated with underlying malignancy in most cases, but in some cases can stem from an autoimmune disease, messenger RNA-based vaccines against COVID-19, or in rare cases, tuberculosis (TB). The case report from authors at Stanford University is published in Annals of Internal Medicine.
Dr. Marcus Bosenberg, an accomplished clinician, teacher, and researcher who studies the factors that regulate anti-cancer immune responses, was recently appointed the Anthony N. Brady Professor of Dermatology, Pathology, and Immunobiology, effective immediately.Bosenberg received his Ph.D. and M.D. at Cornell University Medical College.
A team of researchers from institutions across the United States, including Moffitt Cancer Center, launched a phase 2 clinical trial evaluating a new treatment option for this patient population. Their results, published in The New England Journal of Medicine, show that treating resectable stage 3 and 4 melanoma patients with the immunotherapy drug pembrolizumab both before and after surgery greatly improves outcomes when compared to pembrolizumab given only after surgery.
Led by the UN Environment Programme (UNEP), with funding from the Global Environment Facility, and executed by the World Health Organization (WHO) and Biodiversity Research Institute (BRI), the Eliminating mercury skin lightening products project will work to reduce the risk of exposure to mercury-added skin lightening products, raising awareness of the health risks associated with their use, developing model regulations to reduce their circulation, and halting production, trade, and distribution across domestic and international markets.
Demographic factors including low income and living in a rural area are linked to low telemedicine literacy – which may limit access to plastic surgeons and other healthcare providers at a time of expanding use of telehealth and video visits, according to a report in the March issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a new understanding of how HPV drives cancer development, a combination therapy to overcome treatment resistance in mantle cell lymphoma, novel insights into memory T cell formation and potential therapeutic strategies for brain cancers, improved survival outcomes for metastatic colorectal cancer, targeting myeloperoxidase to improve immunotherapy responses in melanoma, and preclinical results of a combination therapy that could effectively treat a subset of acute myeloid leukemia.
Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an “incredibly promising” treatment for alcohol use disorder.