Research from Osaka University demonstrates a nanopore-based technique that can detect different variants of SARS-CoV-2, the virus that causes COVID-19. The method was very effective in detecting the Omicron variant of the virus in the saliva of people with COVID-19.
Researchers at Wake Forest University School of Medicine have received a five-year, $9 million grant from the National Institute on Aging, part of the National Institutes of Health, to create a national consortium that will study the use, interpretation and implementation of biomarkers to diagnose Alzheimer's disease.
Layered lithium cobalt oxide, a key component of lithium-ion batteries, has been synthesized at temperatures as low as 300°C and durations as short as 30 minutes.
Navigating the labyrinthine vasculature of the brain with standard surgical instruments can be incredibly challenging, even for the steadiest of hands. But with some robotic assistance, brain surgeons could potentially operate with far greater ease.
Researchers have developed soft yet durable 3D-printed materials that glow in response to mechanical stress, such as compression, stretching or twisting. The materials derive their luminescence from single-celled algae known as dinoflagellates, which are embedded within the materials. The work was inspired by the bioluminescent waves caused by dinoflagellates during red tide events at San Diego’s beaches.
LA JOLLA, CA—Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma. These cells, called cytotoxic CD4+ tissue-resident memory T cells, gather in the lungs and appear to possess the molecular weaponry to cause the most harm in men who developed asthma later in life.
A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.
A UC Davis study shows the first-in-human imaging of the body’s CD8 T cell immune response to COVID-19 infection in recovering patients.
Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or “subway map” of key metabolic activities of the bacterium that causes Lyme disease.
UC San Diego engineers have developed a recipe to make a certain class of ceramics tougher and more resistant to cracking. The newfound toughness of these ceramics paves the way for their use in extreme applications, such as spacecraft and other hypersonic vehicles.
Iowa State researchers are developing mathematical models to simulate soybean aphid population dynamics over a growing season with a wide array of stressors, including droughts and floods. The project received a USDA grant earlier this year and is in collaboration with entomologists at Ohio State University.
Researchers from Iowa State University and the University of California, Santa Barbara will work together to fundamentally change the capabilities of light-based 3D printing.
Wake Forest University School of Medicine has received a two-year, $445,000 grant from the National Institute on Minority Health and Health Disparities, part of the National Institutes of Health.
UC San Diego engineers have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs. Its success lies in targeting a protein known to play a central role in cancer growth and spread, rather than targeting the primary tumor itself.
Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen.
Most people think of dementia as something that affects a person’s brain. But a new study shows just how much damage it does to a person’s wallet and bank account too – as well as the higher demands it places on their family members -- compared with people of the same age in similar health but without dementia.
Worries that surgery patients would have a tougher recovery if their doctors had to abide by a five-day limit on opioid pain medication prescriptions didn’t play out as expected, a new study finds. Instead, patient-reported pain levels and satisfaction didn’t change at all for Michigan adults who had their appendix or gallbladder removed, a hernia repaired, a hysterectomy or other common operations after the state’s largest insurer put the limit in place, the study shows.
Police officers often respond to incidents that do not involve crime or immediate threats to public safety but instead deal with community members facing unmet mental health needs. In response to this, many cities are experimenting with co-deploying police officers alongside health professionals or deploying teams entirely composed of civilian health professionals.
An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States. Doctors may be able to target these genes with existing medications – or possibly even nutritional supplements – to slow or halt the disease’s progression.
In a new article published today in Science Translational Medicine, a team of Moffitt Cancer Center researchers, in collaboration with NFlection Therapeutics and researchers at Stanford University, reports the identification of a new drug, NFX-179, that can be applied to the skin and was shown to prevent the development of cutaneous squamous cell carcinoma in pre-clinical models.
A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science researchers report in a new study that exposures to two of the most popular herbicides were associated with worse brain function among adolescents.
UC San Diego engineers developed electronic “stickers” that measure the force exerted by one object upon another. The force stickers are wireless, run without batteries and fit in tight spaces, making them versatile for a wide range of applications, from surgical robots to smart implants and inventory tracking.
Models built on machine learning in health care can be victims of their own success, according to researchers at the Icahn School of Medicine and the University of Michigan.
To improve the quality of care and reduce healthcare expenditures, heart failure patients in the U.S. are increasingly being treated in community-based programs such as managed long-term care. Although early identification of patients’ risks of negative outcomes, including hospitalizations or emergency department visits, has been shown to prevent these adverse outcomes in settings including hospitals and nursing homes, it has not been studied in managed long-term care.
A groundbreaking study presented today by University of North Carolina (UNC) School of Medicine researchers at the XXIV FIGO World Congress of Gynecology and Obstetrics could revolutionize pregnancy care, especially in areas with limited resources.
Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells). When used in patients with advanced non-small cell lung cancer undergoing immunotherapy, they may identify patients who could benefit from treatment with additional drugs, according to a phase 2 clinical trial in the U.S. and Canada. The trial is led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, BC Cancer and the Canadian Cancer trials Group (CCTG).
In 2019, St. Jude lentiviral gene therapy restored the immune system in multiple infants of X-linked severe combined immunodeficiency disorder (SCID-X1) or “bubble boy disease” at the DNA level. These children can now produce functional immune systems.
Borrowing from neuroscience, researchers at the University of Pittsburgh will engineer neural networks for robots, giving them the ability to learn and improve their ability to navigate different terrains.
In a study co-led by investigators at Dana-Farber Cancer Institute, researchers developed a low-cost, ultrasensitive blood test to detect minute levels of a cancer biomarker that is highly specific to multiple common cancers.
A technology being studied to curb climate change – one that could be put in place in one or two decades if work on the technology began now – would affect food productivity in parts of planet Earth in dramatically different ways, benefiting some areas, and adversely affecting others, according to projections prepared by a Rutgers-led team of scientists.
Researchers at Wake Forest University School of Medicine have received a five-year $10 million grant from the National Institute on Drug Abuse, part of the National Institutes of Health (NIH), to create a broad research program that will work to reduce opioid-related harms and improve quality of life in patients on long-term opioid therapy.
Gadgets and vehicles powered by the very materials they’re built from may soon be possible, thanks to a new structural supercapacitor developed by UC San Diego engineers. The device doubles as structural support and energy storage, potentially adding more energy capacity without adding weight.
A research team has won a four-year, $14 million grant to design a national testing facility that will simulate tornadoes and other windstorms. Experiments will measure the loads that windstorms exert on structures and help researchers engineer building improvements that can reduce damage and save lives.
Acoels have been found to host a wide diversity of symbiotic, photosynthetic microalgae.
The three-year grant is earmarked for the purchase of an additional high-performance computer cluster to join existing MERCURY resources hosted offsite. The grant will enable 13 more undergraduate-focused research groups to benefit, growing the consortium to 47 computational scientists at 41 institutions nationwide.
The decision to reach for a sugar sweetened beverage is heavily influenced by where you live, Tufts University researchers report in a new study that provides a snapshot of how adults in 185 countries imbibe sugar-sweetened beverages.
The Resource Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans will work to advance behavioral, social and economic research related to Alzheimer’s disease and other dementias especially in older Asian and Pacific Americans.
IDRs comprise a large percentage of the human proteome and are particularly important for nuclear proteins that govern our genomic architecture and gene expression.
As one of just six sites in the country chosen for a new consortium of the National Institutes of Health (NIH), UTHealth Houston School of Public Health in Brownsville will use multi-omics in combination with environmental, epidemiologic, and clinical data, along with social determinants of health, to study non-alcoholic and non-viral liver disease in Hispanics/Latinos.
Researchers at Dana-Farber Brigham Cancer Center have found that a shorter course of radiation therapy after mastectomy and breast reconstruction surgery provides the same protection against breast cancer recurrence and equivalent physical side-effects but substantially reduces life disruption and financial burden for patients.
The reasons why people attempt suicide are complex and include external triggers like trauma and stress, as well as inherited genetic factors. A new study has identified 12 DNA variants, or variations in the human genetic code, that are associated with risk of attempting suicide.
Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body’s own, healthy tissues. The study, to be published September 29 in the Journal of Experimental Medicine (JEM), also reveals how this process is impaired in autoimmune disorders such as systemic sclerosis and systemic lupus erythematosus and suggests potential new strategies to treat these diseases.
CLEVELAND: A team from Cleveland Clinic has developed a new model for prioritizing patients waiting for a lung transplant, aimed at improving outcomes and reducing deaths among those in need of donor lungs. The new method offers an improved strategy for organ allocation by taking into account how the time a patient has spent on the waiting list could impact the severity of their disease and the urgency of their need for a transplant. The results of a study looking at this new method were published today in The American Journal of Respiratory and Critical Care Medicine.
Concave, umbrella-like metal complexes provide space to enable the largest molecular rotor operational in the solid-state.
Researchers at Washington University in St. Louis have developed a technique called sonobiopsy that uses ultrasound and microbubbles to disrupt the blood-brain barrier temporarily and allow RNA, DNA and proteins from the brain to spill out into the blood, where they can be detected and analyzed.
In a groundbreaking study, a team of Georgia Tech researchers has unveiled a remarkable discovery: the identification of novel bacterial proteins that play a vital role in the formation and stability of methane clathrates, which trap gigatons of greenhouse gas beneath the seafloor. These newfound proteins not only suppress methane clathrate growth as effectively as toxic chemicals used in drilling but also prove to be eco-friendly and scalable. This innovative breakthrough not only promises to enhance environmental safety in natural gas transportation but also sheds light on the potential for similar biomolecules to support life beyond Earth.
Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.
Penn State College of Medicine researchers said they conducted a “first-of-its-kind study,” revealing how various demographic factors intersect to affect a person’s risk of having suicidal thoughts and behaviors.
The normal brain protein tau sometimes gets knotted up into tangles and turns toxic, injuring brain tissue and causing tauopathies, a group of brain diseases characterized by problems with learning, memory and movement.
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