Curated News: JAMA

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Newswise: Genome Sequencing Nearly Twice as Effective as a Targeted Gene-Sequencing Test at Diagnosing Genetic Disorders in Newborns and Infants
10-Jul-2023 9:00 AM EDT
Genome Sequencing Nearly Twice as Effective as a Targeted Gene-Sequencing Test at Diagnosing Genetic Disorders in Newborns and Infants
Tufts University

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

Newswise: Anti-inflammatory drugs did not speed COVID-19 recovery but prevented deaths
Released: 10-Jul-2023 3:15 PM EDT
Anti-inflammatory drugs did not speed COVID-19 recovery but prevented deaths
Washington University in St. Louis

Two drugs commonly used to treat inflammatory diseases such as rheumatoid arthritis and psoriasis did not shorten recovery time for patients hospitalized with severe COVID-19 but did reduce the likelihood of death when compared with standard care alone, according to a national study led by Washington University School of Medicine in St. Louis.

Released: 10-Jul-2023 12:05 PM EDT
Hospital Understaffing and Poor Work Conditions Associated with Physician and Nurse Burnout and Intent to Leave
University of Pennsylvania School of Nursing

A unique collaborative study on hospital clinician wellbeing by teams at 60 of the nation’s best hospitals, defined by Magnet Hospital Recognition, was published today in JAMA Health Forum. The study found that physicians and nurses, even at hospitals known to be good places to work, experienced adverse outcomes during the pandemic and want hospital management to make significant improvements in their work environments and in patient safety. The solutions to high hospital clinician burnout and turnover, they say, are not resilience training for clinicians to better cope with adverse working conditions but organizational improvements that provide safe workloads and better work-life balance.

Newswise: Cannabis use associated with increased risk of surgical complications, according to UTHealth Houston study
Released: 5-Jul-2023 1:05 PM EDT
Cannabis use associated with increased risk of surgical complications, according to UTHealth Houston study
University of Texas Health Science Center at Houston

People who are regular cannabis users are at an increased risk of experiencing complications before, during, and after surgery, according to a study by researchers with UTHealth Houston published today in JAMA Surgery.

Released: 3-Jul-2023 4:05 PM EDT
Preventing stroke disability in a community with high rate of poverty
Northwestern University

The use of thrombolysis, medications to break up blood clots, for acute ischemic stroke reduces post-stroke disability, but it is underutilized.

29-Jun-2023 3:50 PM EDT
Older Frail Patients Have a 1-in-3 Chance of Surviving CPR During Surgery
Brigham and Women’s Hospital

It’s estimated that around 25% of patients who have a cardiac arrest and receive cardiopulmonary resuscitation (CPR) in a normal hospital setting will survive.

Released: 29-Jun-2023 11:30 AM EDT
Analysis Suggests 2021 Texas Abortion Ban Resulted in Nearly 9,800 Extra Live Births in State In Year After Law Went Into Effect
Johns Hopkins Bloomberg School of Public Health

In a peer-reviewed research letter published online today in JAMA, researchers from the Johns Hopkins Bloomberg School of Public Health estimate that a Texas abortion ban that went into effect in September 2021 was associated with 9,799 additional live births in the state between April and December 2022.

   
Released: 29-Jun-2023 11:00 AM EDT
Study suggests need for iron tests in teen girls & young women
Michigan Medicine - University of Michigan

A national study of blood ferritin and hemoglobin levels from tween, teen and young adult females suggests routine screening might be needed for iron deficiency and anemia.

26-Jun-2023 4:05 PM EDT
Poverty negatively impacts structural wiring in children’s brains, study indicates
Washington University in St. Louis

A study by researchers at Washington University School of Medicine in St. Louis reveals that household and community poverty may influence brain health in children. Childhood obesity and lower cognitive function may explain, at least partially, poverty’s influence on the brain.

   
Newswise: New Research by Sylvester Cancer Shows Unmet Support Needs Can Lead to Worse Clinical Outcomes
Released: 26-Jun-2023 8:05 PM EDT
New Research by Sylvester Cancer Shows Unmet Support Needs Can Lead to Worse Clinical Outcomes
Sylvester Comprehensive Cancer Center

Cancer patients with unmet supportive care needs are more likely to experience worse clinical outcomes, including more emergency department (ED) visits and hospitalizations, according to new research from Sylvester Comprehensive Cancer Center.

26-Jun-2023 9:15 AM EDT
Sicker Americans are sticking with Medicare managed care plans
Ohio State University

Following decades of criticism for “cherry-picking” the healthiest patients, Medicare managed care plans now appear to be holding onto sicker patients with more complex health needs, new research has found. The study, which appears today (June 26, 2023) in the Journal of the American Medical Association, found that older Americans with demanding health needs were not more likely to disenroll from Medicare Advantage, the increasingly popular managed care option for Americans age 65 and over.

Newswise: Warfarin use should not disqualify stroke patients from lifesaving clot-removing surgery
Released: 26-Jun-2023 11:00 AM EDT
Warfarin use should not disqualify stroke patients from lifesaving clot-removing surgery
UT Southwestern Medical Center

Most stroke patients taking the anticoagulant warfarin were no more likely than those not on the medication to experience a brain bleed when undergoing a procedure to remove a blood clot, UT Southwestern Medical Center researchers report in a new study. The findings, published in JAMA, could help doctors better gauge the risk of endovascular thrombectomy (EVT), potentially expanding the pool of eligible patients for this mainstay stroke treatment.

Newswise: “Anchoring bias” can delay testing and diagnosis by physicians for deadly conditions like blood clots in the lung
22-Jun-2023 3:05 PM EDT
“Anchoring bias” can delay testing and diagnosis by physicians for deadly conditions like blood clots in the lung
University of California, Los Angeles (UCLA), Health Sciences

Patients with congestive heart failure experiencing shortness of breath are less likely to be tested in the emergency department for a potentially fatal pulmonary embolism when the reason for the visit is initially noted as congestive heart failure instead of the broader “shortness of breath”.

21-Jun-2023 6:50 PM EDT
The expanded Child Tax Credit led to improved health and nutrition among adults
University of California, Los Angeles (UCLA), Health Sciences

Monthly cash payments to eligible families under the temporary pandemic-era expansion of the federal Child Tax Credit led to better adult health and food security, new UCLA-led research suggests.

Released: 23-Jun-2023 12:55 PM EDT
BP Below 120 Could Be Target to Prevent Common Heart Condition
University of California, San Francisco (UCSF)

UCSF researchers have found that aggressive blood pressure control can lower the risk of left ventricular conduction disease, a common heart condition that often leads to pacemaker implantation.

Released: 22-Jun-2023 4:50 PM EDT
Study improves prediction of therapy response in patients with metastatic renal cell carcinoma
Universitätsklinikum Bonn

Renal cell carcinoma is the most common form of kidney cancer. To treat metastatic renal cancer, combinations of immunotherapies are used as the first line of treatment.

Newswise: New Study Shows Children of Parents with Cancer History in US May be Vulnerable to Housing, Food and Financial Hardship
20-Jun-2023 12:05 PM EDT
New Study Shows Children of Parents with Cancer History in US May be Vulnerable to Housing, Food and Financial Hardship
American Cancer Society (ACS)

A new study by researchers at the American Cancer Society found children of parents with a cancer history in the United States are more at risk of having unmet needs for housing, food, and other living necessities than their counterparts without a parental cancer history. The findings will be published today in the Journal of the American Medical Association (JAMA) Network Open.

16-Jun-2023 2:10 PM EDT
Brain stimulation may prove helpful to acute stroke patients, pilot study suggests
University of California, Los Angeles (UCLA), Health Sciences

There are few effective treatments for acute stroke, and many patients aren’t eligible for them. An innovative pilot study from UCLA Health found promising results for a new potential treatment: highly targeted electrical stimulation to the affected brain area.

Newswise: Wearable activity trackers accelerate hospital patient recovery
Released: 15-Jun-2023 10:05 PM EDT
Wearable activity trackers accelerate hospital patient recovery
University of South Australia

Fitbits, Garmins or Apple Watches, whatever your preference, wearable activity trackers could help patients recover faster during a hospitalisation, potentially easing some pressures on Australia’s overburdened hospital system, according to new research from the University of South Australia.

Released: 15-Jun-2023 2:05 PM EDT
Extensive study links cannabis use disorder to mental disorders
Aarhus University

Cannabis is one of the world's most commonly used illegal drugs. New research suggests that cannabis use disorder is more strongly linked with the development of mental disorders than previously assumed.

Newswise: Estudio: Reparación Transcatéter de la Válvula Mitral Segura y Exitosa
Released: 15-Jun-2023 1:45 PM EDT
Estudio: Reparación Transcatéter de la Válvula Mitral Segura y Exitosa
Cedars-Sinai

Los resultados largamente esperados de los procedimientos transcatéter de extremo a extremo para reparar las válvulas mitrales con fugas revelaron que el procedimiento mínimamente invasivo es seguro y eficaz en cerca del 90 % de los pacientes, de acuerdo a los médicos y científicos de Cedars-Sinai.

15-Jun-2023 10:15 AM EDT
Researchers test AI-powered chatbot's medical diagnostic ability
Beth Israel Deaconess Medical Center

Researchers tested one well-known publicly available chatbot’s ability to make accurate diagnoses in challenging medical cases. The team found that the generative AI, Chat-GPT 4, selected the correct diagnosis as its top diagnosis nearly 40 percent of the time and provided the correct diagnosis in its list of potential diagnoses in two-thirds of challenging cases.

Released: 15-Jun-2023 7:05 AM EDT
‘Concerning’ CT scans may cause unnecessary hospitalization for some pulmonary embolism patients
Michigan Medicine - University of Michigan

Some pulmonary embolism patients may be hospitalized unnecessarily due to CT imaging results rather than clinical risk factors, a study finds. Roughly half of the low risk patients had CT imaging features that physicians consider “concerning”, and these patients fared just as well in the hospital as those whose CT scans showed no concerning findings.

Released: 13-Jun-2023 7:15 PM EDT
Four state policies linked to growth of telehealth at mental health facilities
RAND Corporation

Four state policies introduced during the COVID-19 pandemic to spur expansion of telehealth were associated with expansion of such services by mental health facilities, but growth of telehealth was lower among facilities in counties with the greatest proportion of Black residents, according to a new RAND Corporation study.

Released: 12-Jun-2023 2:10 PM EDT
Research sheds light on low rates of genetic testing for cancer
Michigan Medicine - University of Michigan

Not enough people are getting genetic testing for cancer, according to recent research.

Released: 8-Jun-2023 11:05 AM EDT
Study Finds Disease Progression and Adverse Radiation Effects Are Low in Patients Undergoing Preoperative Stereotactic Radiosurgery
Wake Forest University School of Medicine

In a new study from Wake Forest University School of Medicine and Atrium Health Levine Cancer Institute, researchers highlight improved outcomes for patients treated with preoperative stereotactic radiosurgery, particularly in rates of tumor recurrence, adverse radiation effects and spread of tumor cells to the fluid outside of the brain.

Released: 8-Jun-2023 10:05 AM EDT
“List Diving” Skips Top Candidates Awaiting Donor Kidneys
Columbia University Irving Medical Center

Some centers routinely skip the top kidney transplant candidates on the wait list and give the kidney to lower-ranked patients, finds a new study at Columbia University.

Released: 7-Jun-2023 12:35 PM EDT
Bilingual, digital health tool helps reduce alcohol use, UC Irvine-led study finds
University of California, Irvine

An automated, bilingual, computerized alcohol screening and intervention health tool is effective in reducing alcohol use among Latino emergency department patients in the U.S., according to a study led by the University of California, Irvine. “This is the first bilingual, large-scale, emergency department-based, randomized clinical trial of its kind in the country focused on English- and Spanish-speaking Latino participants,” said lead author Dr.

Released: 7-Jun-2023 12:00 PM EDT
MD Anderson Research Highlights for June 7, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

   
Newswise: Study Finds Functional Limitations Increasing in Survivors of Cancer
Released: 7-Jun-2023 10:00 AM EDT
Study Finds Functional Limitations Increasing in Survivors of Cancer
Johns Hopkins Medicine

The percentage of survivors of cancer reporting functional limitations in the United States has more than doubled over the past 20 years, according to a new study in the journal JAMA Oncology. The work, published May 11, was a collaborative effort from investigators at the Johns Hopkins Kimmel Cancer Center, the Dell Medical School in Austin, Texas, and the University of Minnesota’s Masonic Cancer Center in Minneapolis.

Released: 6-Jun-2023 6:30 PM EDT
New study finds that women and underrepresented groups experience higher rates of sexual harassment, cyber incivility and negative workplace climate in academic medicine
Emory Health Sciences

A new study led by Winship Cancer Institute of Emory University researcher Reshma Jagsi, MD, DPhil, has found that women, racial and ethnic minorities and individuals identifying as lesbian, gay, bisexual, transgender and queer are disproportionately affected by workplace mistreatment in academic medicine, and this mistreatment negatively impacts their mental health.

Released: 6-Jun-2023 12:50 PM EDT
Study: Doing good for others is good for children’s and teens’ mental, physical health
University of Texas Health Science Center at Houston

Children and teenagers who volunteer tend to flourish mentally and physically, according to a new study from UTHealth Houston.

   
Released: 6-Jun-2023 10:40 AM EDT
Hospital Infection Control Experts Question Validity of Public Reporting Metrics, New Study Finds
University of Maryland School of Medicine

Infections spread in hospitals and other healthcare settings cause over 680,000 infections and 72,000 patient deaths in the U.S. every year.

Released: 5-Jun-2023 3:20 PM EDT
Study shows promising treatment for tinnitus
Michigan Medicine - University of Michigan

A randomized controlled clinical trial of a device shows promise for quieting the phantom noises of tinnitus.

2-Jun-2023 8:00 AM EDT
Real-World Data Suggests Stopping Immunotherapy after Two Years is Reasonable in Patients with Advanced Lung Cancer
Perelman School of Medicine at the University of Pennsylvania

A new study from Penn Medicine’s Abramson Cancer Center suggests that it’s reasonable for patients with advanced lung cancer to stop immunotherapy treatment at two years, as long as their cancer hasn’t progressed.

Released: 2-Jun-2023 1:15 PM EDT
Multiple Sclerosis More Prevalent in Black Americans Than Previously Thought
University of Maryland School of Medicine

Multiple sclerosis has traditionally been considered a condition that predominantly affects white people of European ancestry. However, a new analysis conducted by a North American team led by University of Maryland School of Medicine (UMSOM) researchers suggests that the debilitating neurological condition is more prevalent in Black Americans than once thought. It is also far more prevalent in Northern regions of the country including New England, the Dakotas, and the Pacific Northwest.

Not for public release

This news release is embargoed until 2-Jun-2023 11:00 AM EDT Released to reporters: 1-Jun-2023 8:00 AM EDT

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Released: 1-Jun-2023 4:55 PM EDT
Eye drops slow nearsightedness progression in kids, study finds
Ohio State University

The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon.

Newswise: New research shows an uptick in weight loss surgery among youth in US
Released: 1-Jun-2023 4:15 PM EDT
New research shows an uptick in weight loss surgery among youth in US
University of Texas Health Science Center at Houston

More adolescents in the U.S. are undergoing weight loss surgery, according to researchers with UTHealth Houston. The study was published in JAMA Pediatrics.

Released: 1-Jun-2023 11:05 AM EDT
Treating Asymptomatic Elevated Blood Pressure Linked to Cardiac and Kidney Injury
Beth Israel Deaconess Medical Center

Researchers found that receiving intensive antihypertensive treatment as an inpatient was linked with greater risk of adverse events, particularly for patients receiving the medication intravenously as opposed to orally.

Released: 1-Jun-2023 10:35 AM EDT
Tweets Showed Increasing Loneliness Among Emergency Medicine Doctors During COVID-19
Perelman School of Medicine at the University of Pennsylvania

Social media study found a steady increase in expressions of loneliness and depression as the pandemic continued



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