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Released: 14-Sep-2018 10:55 AM EDT
Case Western Reserve’s Dr. Lan Zhou Receives $2M NIH Grant to Study Colorectal Cancer Development
Case Western Reserve University

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer. Her work focuses on the effect of the imbalance of the gut microbiome, the immune response, and genetics in the development of adenocarcinoma (cancer that forms in the lining of the glands) through the serrated pathway.

Released: 13-Sep-2018 4:35 PM EDT
Study: Antibiotics Destroy Immune Cells and Worsen Oral Infection
Case Western Reserve University

New research shows that the body’s own microbes are effective in maintaining immune cells and killing certain oral infections.

Released: 13-Sep-2018 8:05 AM EDT
Jordan M. Winter, MD, Appointed Chief of Surgical Oncology at UH Cleveland Medical Center and Director of Surgical Services at UH Seidman Cancer Center
University Hospitals Cleveland Medical Center

Announcement of Jordan M. Winter, MD, being appointed Chief of the Division of Surgical Oncology at University Hospitals Cleveland Medical Center and Director of Surgical Services at UH Seidman Cancer Center. Dr. Winter comes to UH from Thomas Jefferson University Hospitals, Philadelphia, where he served as Co-Director of the Jefferson Pancreas, Biliary and Related Cancer Center, Co-Director of the GI Multidisciplinary Clinical Trials Group in the Sidney Kimmel Cancer Center, and Co-Director of the Multidisciplinary Pancreas Cancer Clinic.

Released: 13-Sep-2018 7:50 AM EDT
The Trust Older Patients Place in Doctors Can Compromise Their Medical Care: Study
Case Western Reserve University

Placing trust in doctors to advocate for their health needs, older adults rarely ask for referrals to specialists, specific prescriptions, express concerns or follow-up after medical visits.

10-Sep-2018 2:00 PM EDT
Timing May Be Everything When Taking Meds
Cincinnati Children's Hospital Medical Center

Using new bioinformatics tools to analyze thousands of human tissue samples, researchers created a new database of daily rhythms in human gene activity—including many genes that regulate how drugs work. Reporting in Science Translational Medicine, scientists say their results could have significant implications for a growing field of study called circadian medicine.

Released: 12-Sep-2018 12:05 PM EDT
University Hospitals in Cleveland awarded $200,000 from Ohio Opioid Technology Challenge for innovative UH Ventures Care Continues technology solution
University Hospitals Cleveland Medical Center

The Ohio Opioid Technology Challenge has awarded University Hospitals system in Northeast Ohio a $200,000 grant for a technology solution to help health professionals when assessing a patient's risk for opioid misuse.

Released: 12-Sep-2018 10:05 AM EDT
James E. Voos, MD, named new Chair of Department of Orthpaedics at University Hospitals Cleveland Medical Center
University Hospitals Cleveland Medical Center

Announcement of James E. Voos, MD, to the Chair of the Department of Orthopaedics at University Hospitals Cleveland Medical Center.

Released: 11-Sep-2018 11:05 AM EDT
Stress Linked to More Advanced Disease in Some Leukemia Patients
Ohio State University

Patients with chronic lymphocytic leukemia (CLL) who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease.

Released: 10-Sep-2018 11:45 AM EDT
Scientists Block RNA Silencing Protein in Liver to Prevent Obesity and Diabetes in Mice
Cincinnati Children's Hospital Medical Center

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions.

Released: 6-Sep-2018 2:05 PM EDT
Dr. Anthony Wynshaw-Boris Elected President of the American Society of Human Genetics
Case Western Reserve University

Anthony Wynshaw-Boris, MD, PhD, the James H. Jewell MD ’34 Professor of Genetics and chair of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center and Rainbow Babies & Children’s Hospital, has been elected as president of the American Society of Human Genetics, the primary professional membership organization for human genetics worldwide.

Released: 6-Sep-2018 1:05 PM EDT
Nicole Maronian, MD, Appointed Chair of Otolaryngology – Head & Neck Surgery at University Hospitals Cleveland Medical Center
University Hospitals Cleveland Medical Center

Nicole C. Maronian, MD, has been named Chair of the Department of Otolaryngology – Head & Neck Surgery at University Hospitals Cleveland Medical Center. She will continue to serve as Director of the institute. She is also an Associate Professor of Otolaryngology – Head & Neck Surgery at Case Western Reserve University School of Medicine. Dr. Maronian, the first female surgical department Chair for UH, previously served as Director of the Voice and Swallowing Center at UH Cleveland Medical Center as well as the ENT Vice Chair for Education and Quality, and the Residency Program Director, Otolaryngology – Head & Neck Surgery.

Released: 5-Sep-2018 9:05 AM EDT
Graphic Images on Cigarette Warnings Stick with Smokers
Ohio State University

If you want smokers to remember cigarette-warning labels, include a graphic image of the results of long-term smoking, a new study suggests.

Released: 4-Sep-2018 1:05 PM EDT
Study Finds You Act Most Like “You” in a Time Crunch
Ohio State University

When they must act quickly, selfish people are likely to act more selfishly than usual, while pro-social people behave even more pro-socially, a new study found.

Released: 4-Sep-2018 7:00 AM EDT
A Terrain Map That Shows Antarctica in Stunning Detail
Ohio State University

Scientists have released the most accurate, high-resolution terrain map of Antarctica ever created. The new map has a resolution of 2 to 8 meters, compared to 1,000 meters, which was typical for previous maps. “It is the highest-resolution terrain map by far of any continent,” said Ian Howat, professor of earth sciences at The Ohio State University.

31-Aug-2018 2:00 PM EDT
Scientists Identify Hormone Link Between Diabetes and Hypertension
Ohio State University Wexner Medical Center

Physician researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.

28-Aug-2018 9:30 AM EDT
New Program Boosts Use of HIV Medications in Injection-Drug Users
Ohio State University

A relatively simple effort to provide counseling and connect injection-drug users with resources could prove powerful against the spread of HIV in a notoriously hard-to-reach population, new research suggests.

Released: 30-Aug-2018 10:05 AM EDT
Research to Examine How Blood Flow Influences Plaque Buildup
Ohio State University

Biomedical Engineering Professor Rita Alevriadou has spent most of her career, which spans two decades, on cardiovascular disease. Her current research on the effects of blood flow on our artery walls recently earned a $1.8 million grant from the National Institutes of Health (NIH).

27-Aug-2018 7:00 AM EDT
Cleveland Clinic-Led Trial Shows Unprecedented Slowing in Progressive Multiple Sclerosis
Cleveland Clinic

A promising drug slowed brain shrinkage in progressive multiple sclerosis (MS) by nearly half, according to new research led by Cleveland Clinic. Very limited therapies are currently available for this disabling form of the disease. The definitive results of the phase 2 trial – published in the New England Journal of Medicine – showed that the drug ibudilast decreased progression of brain atrophy in progressive MS patients by 48 percent versus placebo.

Released: 29-Aug-2018 8:05 AM EDT
Melting Arctic Ice Revamping World’s Shipping Routes—Prompting China’s “Polar Silk Road” and New Investigation
Case Western Reserve University

Rising temperatures are melting the Arctic ice, opening new shipping routes and prompting world powers to jostle for access and control.

Released: 28-Aug-2018 11:05 AM EDT
Close Ties with Fathers Help Daughters Overcome Loneliness
Ohio State University

Fathers play a key role in helping their young daughters overcome loneliness, a new study has found.

27-Aug-2018 4:05 PM EDT
Novel Imaging Biomarker to Help Predict Coronary Inflammation
Cleveland Clinic

Munich, Germany: Researchers at Cleveland Clinic, University of Oxford and University of Erlangen have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries.

Released: 27-Aug-2018 4:05 PM EDT
Algae a Threat to Walleye Vision, Study Finds
Ohio State University

Walleye and the fish they eat struggle to see in water clouded by algae, and that could potentially jeopardize the species’ future if harmful algal blooms persist, according to a new study.

Released: 24-Aug-2018 2:05 PM EDT
Researchers Stop Cell Suicide that Worsens Sepsis, Arthritis
Case Western Reserve University

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death.

Released: 23-Aug-2018 12:05 PM EDT
Algal blooms a threat to small lakes and ponds, too
Ohio State University

Harmful algae isn’t just a problem for high-profile bodies of water – it poses serious, toxic threats in small ponds and lakes as well, new research has found.

Released: 23-Aug-2018 12:30 AM EDT
Scientists Close in on Mystery Surrounding Dangerous Blood Syndromes
Cincinnati Children's Hospital Medical Center

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia. Researchers report in the journal Cancer Discovery identifying a gene that in laboratory experiments fuels the biological processes that cause the different types of MDS that physicians see in patients.

Released: 22-Aug-2018 4:05 PM EDT
University Hospitals Recruits Talented Geneticist to Join Harrington Discovery Institute
University Hospitals Cleveland Medical Center

Announcement of new genetics researcher, Atul Chopra, MD, PhD, for the Harrington Discovery Institute at University Hospitals.

21-Aug-2018 11:00 AM EDT
Cleveland Clinic Researchers Discover Novel Subtype of Multiple Sclerosis
Cleveland Clinic

Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis (MS), providing a better understanding of the individualized nature of the disease. The findings, published in The Lancet Neurology, could potentially lead to more personalized diagnosis and treatments.

Released: 21-Aug-2018 4:40 PM EDT
Graduate Student Digs Deep for Algae Solution
Bowling Green State University

BGSU graduate student Josephine Lindsey-Robbins is researching the role of “bugs” in composting dead plant material, turning it back into the soil and keeping its nitrogen and phosphorus in place. There, it can fertilize the soil instead of washing into lakes.

Released: 21-Aug-2018 2:05 PM EDT
How the United States Landed in a Debt “Danger Zone”
Ohio State University

The interaction of public and private debt in the United States reduced economic growth about 0.43 percentage points per year between 2009 and 2014, a new study suggests. In addition, growth declined an additional 0.40 percent due solely to high levels of private debt, taking into account public debt.

   
21-Aug-2018 8:00 AM EDT
7 Percent of Children in Orthodontic Care at ‘High Risk’ for Sleep Disorders, According to New CWRU Research
Case Western Reserve University

A new study by Case Western Reserve researchers at the School of Dental Medicine found that about 7 percent of children between ages 9 and 17 in orthodontic care were at high risk for sleep-disordered breathing.

Released: 16-Aug-2018 2:05 PM EDT
Case Western Reserve Receives Major Grant to Improve Food Systems in Cleveland Neighborhoods
Case Western Reserve University

A multidisciplinary research team led by Case Western Reserve University School of Medicine has received a three-year, $936,000 grant to use collaborative computational modeling approaches to promote better community health through more equitable food systems.

Released: 15-Aug-2018 8:05 AM EDT
How Ugly Marital Spats Might Open the Door to Disease
Ohio State University

Married people who fight nastily are more likely to suffer from leaky guts – a problem that unleashes bacteria into the blood and can drive up disease-causing inflammation, new research suggests.

Released: 14-Aug-2018 4:05 PM EDT
Immune Cells in the Brain Have Surprising Influence on Sexual Behavior
Ohio State University

Immune cells usually ignored by neuroscientists appear to play an important role in determining whether an animal’s sexual behavior will be more typical of a male or female, according to research.

Released: 14-Aug-2018 1:05 PM EDT
Experts Recommend Talking with Youth about Suicide
Nationwide Children's Hospital

According to suicide prevention experts, asking a child directly about suicidal thoughts is usually the best thing a parent can do to help their child open up about their emotions. Even if their child is not struggling with suicide or depression, parents can model for their child that it is good to talk about serious emotional concerns with trusted adults and important to reach out to friends to have these conversations, too.

14-Aug-2018 12:05 AM EDT
U.S. News & World Report Once Again Names University Hospitals Cleveland Medical Center Among Nation’s Best Hospitals
University Hospitals Cleveland Medical Center

In U.S. News & World Report's annual ranking of the nation's hospitals, University Hospitals Cleveland Medical Center once again ranks among the best.

Released: 13-Aug-2018 3:45 PM EDT
University Hospitals Seidman Cancer Center Opens Car-T Therapy Study for Non-Hodgkin’s Lymphoma
University Hospitals Cleveland Medical Center

University Hospitals Seidman Cancer Center in Cleveland has a new clinical trail to study the safety of CAR-T therapy for Non-Hodgkin's lymphoma. In addition, UH is manufacturing on-site the cells used in the trial.

Released: 13-Aug-2018 1:05 PM EDT
Why zebrafish (almost) always have stripes
Ohio State University

A mathematical model helps explain the key role that one pigment cell plays in making sure each stripe on a zebrafish ends up exactly where it belongs.

Released: 13-Aug-2018 10:35 AM EDT
Positive coping strategy in Islam linked with less depression, anxiety from spiritual struggles
Case Western Reserve University

Adopting an Islamic concept of coping with spiritual struggles, known as “spiritual jihad,” is associated with post-traumatic growth and virtuous behaviors—and related to reductions in anxiety and depression, according to a new Case Western Reserve University study published in the journal Religions.

Released: 13-Aug-2018 10:05 AM EDT
When These Flies Want to Sniff Out Food and Mates, They Wing It
Ohio State University

Fruit flies don’t appear to use their tiny, translucent wings for optimal flight, as one might expect. The speedy appendages seem to be doing double duty, helping the insect sniff out food, mates and other important scents, according to new research from The Ohio State University.

10-Aug-2018 11:05 AM EDT
Black Male Youth More Fearful When Visiting Whiter Neighborhoods
Ohio State University

Young black males feel less safe when they go to neighborhoods with a larger white population than occurs in areas they normally visit, a new study suggests.

Released: 9-Aug-2018 11:05 AM EDT
Case Western Reserve Researcher and International Colleagues Identify Genetic Mutation Underlying Severe Childhood Brain Disorder
Case Western Reserve University

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children. The findings, published in Nature Genetics, identify mutations in the alpha-N-catenin gene, (aka CTNNA2), which promotes cell adhesion and causes pachygyria, one of the most serious developmental brain defects in humans. Most patients are severely intellectually impaired, and are unable to walk or care for themselves. Children diagnosed with the rare disease have a life expectancy of about 10 years.

Released: 8-Aug-2018 3:05 PM EDT
Harrington Discovery Institute Announces New Scholars
University Hospitals Cleveland Medical Center

The Harrington Discovery Institute at University Hospitals in Cleveland, Ohio—part of The Harrington Project for Discovery & Development—has announced three new scholars in collaboration with its partners Foundation Fighting Blindness (FFB) and Alzheimer’s Drug Discovery Foundation (ADDF). Harrington Discovery Institute collaborates with FFB on the Gund-Harrington Award to accelerate therapies for retinal degenerative diseases and ADDF to advance the development of drugs to prevent and treat Alzheimer’s disease.

Released: 8-Aug-2018 11:05 AM EDT
Cleveland Clinic Researchers Receive $4.7M NIH Grant to Prevent Cancer-Associated Thrombosis
Cleveland Clinic

The National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots. The new funding will support a Cleveland Clinic-led research consortium, which will focus on developing strategies to prevent cancer-associated thrombosis (blood clot formation), a potential side effect of cancer treatment.

Released: 7-Aug-2018 1:45 PM EDT
Taking a Pill Can Effectively Treat Brutal Lung Disease
Cincinnati Children's Hospital Medical Center

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills called statins can effectively treat the disease.

Released: 6-Aug-2018 11:05 AM EDT
Potential New Class of Drugs May Reduce Cardiovascular Risk by Targeting Gut Microbes
Cleveland Clinic

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. The research, published in the September issue of Nature Medicine, was led by Stanley Hazen, M.D., Ph.D.

Released: 6-Aug-2018 10:05 AM EDT
Novel Vaccine Approach Proves Powerful Against Zika Virus
Ohio State University

A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, new research has found.

1-Aug-2018 4:00 PM EDT
Juvenile Diversion Programs Work, but New CWRU Research Shows They Also Curb Tendencies to Reoffend in Early Adulthood
Case Western Reserve University

Juveniles who complete diversion programs for their crimes are less likely to continue their criminal activity as adults, according to new research from Case Western Reserve University.



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