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  • Embargo expired:
    7-Jul-2011 12:00 PM EDT

Article ID: 578372

Control of Gene Expression: Mediator MED26 Shifts an Idling Polymerase Into High Gear

Stowers Institute for Medical Research

A report from the Conaway lab at the Stowers Institute for Medical Research in the July 8, 2011, edition of the journal Cell identifies a switch that allows RNA polymerase to shift gears from neutral into drive and start transcribing. This work sheds light on a process fundamental to all plant or animal cells and suggests how transcriptional anomalies could give rise to tumors.

Released:
5-Jul-2011 11:00 AM EDT

Channels:

Cell Biology, Genetics

Article ID: 578417

Discovering The Bigger Picture In Chromosomes

Kansas State University

By mapping various genomes onto an X-Y axis, a team comprised mostly of Kansas State University researchers has found that Charles Darwin and a fruit fly -- among other organisms -- have a lot in common genetically.

Released:
6-Jul-2011 10:15 AM EDT
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  • Embargo expired:
    5-Jul-2011 12:05 PM EDT

Article ID: 578235

Surprising Culprits Behind Cell Death from Fat and Sugar Overload

Washington University in St. Louis

Excess nutrients, such as fat and sugar, don’t just pack on the pounds but can push some cells in the body over the brink. Unable to tolerate this “toxic” environment, these cells commit suicide. Now, scientists at Washington University School of Medicine in St. Louis have discovered three unexpected players that help a cell overloaded with fat initiate its own demise.

Released:
28-Jun-2011 5:00 PM EDT
  • Embargo expired:
    5-Jul-2011 12:00 PM EDT

Article ID: 578323

Researchers Flip the Switch Between Development and Aging in C. elegans

Buck Institute for Research on Aging

When researchers at the Buck Institute dialed back activity of a specific mRNA translation factor in adult nematode worms they saw an unexpected genome-wide response that effectively increased activity in specific stress response genes that could help explain why the worms lived 40 percent longer under this condition. The study highlights the importance of mRNA translation in the aging process.

Released:
30-Jun-2011 3:35 PM EDT
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Article ID: 578371

Researchers Characterize Biomechanics of Ovarian Cells in Mice

Virginia Tech

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal.

Released:
5-Jul-2011 11:00 AM EDT

Article ID: 578368

Scientists Help Unravel How Deadly Ebola Virus Works

University of Virginia Health System

Molecular and cell biologists at the University of Virginia Health System have discovered new information about how the Ebola virus works that could eventually lead to new drug treatments for the deadly virus.

Released:
5-Jul-2011 10:00 AM EDT

Article ID: 578339

Environs Prompt Helpful Mutations as Plants Grow; Changes Passed On

Case Western Reserve University

A Case Western Reserve University researcher has found that the environment not only weeds out harmful and useless mutations through natural selection, but actually influences helpful mutations, which are passed to the next generation. He challenges peers to repeat the controversial findings.

Released:
1-Jul-2011 11:10 AM EDT

Channels:

Cell Biology

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Article ID: 578333

Mutations Can Spur Dangerous Identity Crisis in Cells

Michigan Medicine - University of Michigan

A new U-M study bring us one step closer to developing treatments for issues associated with aging or chronic diseases in which cells lose their ability to maintain a stable pattern of gene expression.

Released:
1-Jul-2011 8:00 AM EDT
  • Embargo expired:
    30-Jun-2011 5:00 PM EDT

Article ID: 578288

The Genome Guardian’s Dimmer Switch: Regulating p53 Is a Matter of Life Or Death

Salk Institute for Biological Studies

Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when they show signs of DNA damage, and it is responsible for much of the tissue destruction that follows exposure to ionizing radiation or DNA-damaging drugs such as the ones commonly used for cancer therapy. The new finding shows that a short segment on p53 is needed to fine-tune the protein’s activity in blood-forming stem cells and their progeny after they incur DNA damage.

Released:
30-Jun-2011 8:00 AM EDT
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Article ID: 578240

Nervous System Stem Cells Can Replace Themselves, Give Rise to Variety of Cell Types, Even Amplify

Johns Hopkins Medicine

A Johns Hopkins team has discovered in young adult mice that a lone brain stem cell is capable not only of replacing itself and giving rise to specialized neurons and glia – important types of brain cells – but also of taking a wholly unexpected path: generating two new brain stem cells.

Released:
29-Jun-2011 9:00 AM EDT

Showing results 59515960 of 6205

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