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Newswise: Researchers engineer insulin-producing cells activated by light for diabetes

Researchers engineer insulin-producing cells activated by light for diabetes

Tufts University

Researchers have transplanted engineered pancreatic beta cells into diabetic mice, then caused the cells to produce more than two to three times the typical level of insulin by exposing them to light. The light-switchable cells are designed to compensate for the lower insulin production or reduced insulin response found in diabetic individuals.

Channels: All Journal News, Diabetes, Engineering, Pharmaceuticals, Grant Funded News,

Released:
1-Nov-2019 4:15 PM EDT
Research Results
Newswise: Scientists unveil search-and-replace genome editing

Scientists unveil search-and-replace genome editing

National Institute of Biomedical Imaging and Bioengineering

Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.

Channels: All Journal News, Cell Biology, Genetics, National Institutes of Health (NIH), Nature (journal), Grant Funded News,

Released:
1-Nov-2019 9:50 AM EDT
Research Results
Newswise: Kidney Cancer Study Uncovers New Subtypes and Clues to Better Diagnosis and Treatment

Kidney Cancer Study Uncovers New Subtypes and Clues to Better Diagnosis and Treatment

Johns Hopkins Medicine

In what is believed to be the most comprehensive molecular characterization to date of the most common — and often treatment-resistant — form of kidney cancer, researchers at Johns Hopkins’ departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them. Their findings could inform overall patient survival and response to treatment.

Channels: All Journal News, Cancer, Cell Biology, Kidney Disease, Cell (journal), Grant Funded News,

Released:
31-Oct-2019 11:20 AM EDT
Research Results
Newswise: A kinase identified as possible target to treat heart failure

A kinase identified as possible target to treat heart failure

University of Alabama at Birmingham

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and restoring the amount of this kinase in a kinase-depleted mouse model rescued the animal from heart failure.

Channels: All Journal News, Cardiovascular Health, Heart Disease, Grant Funded News,

Released:
31-Oct-2019 10:05 AM EDT
Research Results
Newswise: Novel Research Aims to Identify New Medications 
for the Treatment of Opioid Use Disorder

Novel Research Aims to Identify New Medications for the Treatment of Opioid Use Disorder

University of Pennsylvania School of Nursing

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

Channels: All Journal News, Grant Funded News, Addiction, Drugs and Drug Abuse, Nursing, Substance Abuse,

Released:
31-Oct-2019 9:30 AM EDT
Research Results
JHSPH-new-logo.jpg

Screening Tool Administered in Pediatric ER Accurately Gauges Suicide Risk

Johns Hopkins Bloomberg School of Public Health

A suicide risk screening tool that Johns Hopkins Medicine implemented in its pediatric emergency department six years ago appears to provide an accurate gauge of which youth are most vulnerable and has identified more than 2,000 patients who might benefit from mental health treatment and resources, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins Medicine

Channels: All Journal News, Behavioral Science, Children's Health, Psychology and Psychiatry, Substance Abuse, JAMA, Grant Funded News,

Released:
31-Oct-2019 8:30 AM EDT
Research Results
Newswise: Astronomers Catch Wind Rushing Out of Galaxy

Astronomers Catch Wind Rushing Out of Galaxy

University of California San Diego

Study’s findings provide direct evidence for the first time of the role of galactic winds—ejections of gas from galaxies—in creating the circumgalactic medium (CGM).

Channels: All Journal News, Grant Funded News, Particle Physics, Physics, Space and Astronomy, Nature (journal),

Released:
30-Oct-2019 4:05 PM EDT
Research Results
Newswise: Study Finds Racial Variation in Post-Operative Care                                              Following Knee Replacement Surgery

Study Finds Racial Variation in Post-Operative Care Following Knee Replacement Surgery

Hospital for Special Surgery

A large study analyzing 107,000 knee replacement surgeries found that African Americans were significantly more likely than white patients to be discharged to an inpatient rehabilitation or skilled nursing facility rather than home care after the procedure. Researchers also found that African American patients under 65 were more likely to be readmitted to the hospital within 90 days of a knee replacement.

Channels: All Journal News, Race and Ethnicity, Surgery, JAMA, Grant Funded News,

Released:
30-Oct-2019 11:40 AM EDT
Research Results
Newswise: Wearable Activity Trackers a Reliable Tool for Predicting Death Risk in Older Adults

Wearable Activity Trackers a Reliable Tool for Predicting Death Risk in Older Adults

Johns Hopkins Medicine

A federally funded study by Johns Hopkins Medicine researchers shows that wearable accelerometers — mechanical sensors worn like a watch, belt or bracelet to track movement — are a more reliable measure of physical activity and better than patient surveys and other methods used by physicians at assessing five-year risk of death in older adults.

Channels: All Journal News, Grant Funded News, Aging, Clinical Trials, Exercise and Fitness, Patient Safety, Seniors, Technology,

Released:
30-Oct-2019 8:00 AM EDT
Research Results

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