Cancer GPS method evaluates model tumor malignancy
Hokkaido UniversityA water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.
A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.
Researchers from McGill University, led by Professor Alanna Watt of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease.
Find the latest research and features on emergency medicine in the Emergency Medicine channel on Newswise.
Infantile epileptic spasms syndrome (IESS), often called infantile spasms, is the most common form of epilepsy seen during infancy. Prompt diagnosis and referral to a neurologist are essential. But research suggests infants are likely to experience delays in referral to a neurologist if their families are from historically marginalized racial/ethnic backgrounds. A new open-access training module for front-line providers from OPENPediatrics, an online learning community launched by Boston Children’s Hospital, aims to change that.
Recent advances in generative AI help to explain how memories enable us to learn about the world, re-live old experiences and construct totally new experiences for imagination and planning, according to a new study by UCL researchers.
Published in 2023, Dr. Simon Shorvon’s The Idea of Epilepsy covers the history of epilepsy from multiple perspectives over the past 160 years. It ends with a tantalizing question: Does epilepsy actually exist? Harvard's Dr. Phillip Pearl interviews Dr. Shorvon.
In 2019, Tiona Stevenson realized she didn’t feel like herself.She couldn’t sleep. She couldn’t focus at work. Something was off, but Tiona couldn’t pinpoint the problem. She spent two long years working through it.“I was working my regular schedule at home and started feeling dizzy all the time.
A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.
This research from UNC-Chapel Hill, published in the journal Nature Communications, opens the door to researching this wirelessly controlled patch to deliver on-demand treatments for neurodegenerative disorders, including Alzheimer’s disease.
A new study in Cell Metabolism by a team from the Monell Chemical Senses Center unravels the internal neural wiring of separate fat and sugar craving pathways in a mouse model. However, combining these pathways overly triggers a desire to eat more than usual.
In a meta-analysis of 5,000 participants, including more than 500 who underwent in-person assessments over two years, multivitamins showed benefits for memory and global cognition.
A combination of cognitive and behavioral strategies, ideally delivered in person by a therapist, maximizes the benefits of cognitive behavioral therapy for insomnia (CBT-I), according to new research.
RUDN University doctors were able to mitigate inflammation in the brain after a traumatic brain injury with the help of intranasal administration of the developed nootropic drug.
After children experienced severe traumatic brain injury, the infusion of bone marrow mononuclear cells derived from the patient’s own bones led to less time spent in intensive care, less intense therapy, and, significantly, the structural preservation of white matter, which constitutes about half the total volume of the brain, according to new research from UTHealth Houston.
UC Davis Health and Kaiser Permanente Division of Research received a $24 million grant from the National Institute on Aging, part of the NIH, to continue the Study of Healthy Aging in African Americans (STAR).
Migraine can impact many aspects of a person’s life, but less is known about how feelings of stigma about the disease affect quality of life. For people with migraine, these feelings of stigma were linked to more disability, increased disease burden and reduced quality of life, according to new research published in the January 17, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Approximately 23% of people diagnosed with Alzheimer’s disease or another related dementia in their 60s and later have cases that can be explained by controllable risk factors such as high blood pressure, diabetes, physical inactivity, and too little or too much sleep, and that percentage varies depending on race and ethnicity, according to a new study published in the January 17, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The Fralin Biomedical Research Institute’s Neuromotor Research Clinic recently published findings in Behavioral Sciences demonstrating improved motor function for a wide range of diagnoses -- including cerebral palsy, stroke, traumatic brain injury, arteriovenous malformation, hemispherectomy, and more -- after receiving the intensive pediatric neurorehabilitation.
Sensors built with a new manufacturing approach are capable of recording activity deep within the brain from large populations of individual neurons--with a resolution of as few as one or two neurons--in humans as well as a range of animal models, according to a study published in the Jan. 17, 2024 issue of the journal Nature Communications.
A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed. The research in mice finds that amnesia and poor memory following head injury is due to inadequate reactivation of neurons involved in forming memories.
Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other organelles generate energy, assemble new molecules and transport cargo. At Sanford Burnham Prebys, Feng will use cryo-EM to reveal new ways to stop or prevent cancers.
A major clinical trial has shown that by using MRI and tracking to guide the delivery of magnetic stimulation to the brains of people with severe depression, patients will see their symptoms ease for at least six months, which could vastly improve their quality of life.
Tactile mechanoreceptors are essential for environmental interaction and movement. Traditional tactile sensors in wearables and robotics often fall short, especially in restoring touch in cases of paralysis.
Neuroscientists from the University of Vienna and the Karolinska Institute in Stockholm have investigated whether playing violent video games leads to a reduction in human empathy.
There are approximately 72,967 neurosurgeons globally, representing a pooled density of 0.93 neurosurgeons per 100,000 individuals, and a median national density of 0.44 neurosurgeons per 100,000 individuals.
A study exploring the mechanisms behind why cognitive performance improves in response to exercise, has found that dopamine plays a key role.
Is it possible to amp up the energy production of mitochondria, the “power centers” of cells, without also boosting potentially harmful byproducts? If so, such a method could be used to treat a host of neurodegenerative diseases in which impaired mitochondria are believed to play a central role.
New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer’s disease, to a type of brain cancer known as glioma.
Larry Goldstein, M.D., chair of the University of Kentucky Department of Neurology, has been selected to serve as co-chair of The Kentucky Heart Disease and Stroke Prevention (KHDSP) Task Force representing stroke systems of care across the state.
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the first ALS care provider in the United States to offer patients a new interventional clinical study.
A new study has found that stress, through its propensity to drive up inflammation in the body, is linked to metabolic syndrome – leading researchers to suggest that cheap and relatively easy stress-management techniques may be one way to help improve biological health outcomes.
In an article just published in Physica A, researchers from Bar-Ilan University in Israel show how shallow learning mechanisms can compete with deep learning.
A study of mutant models of fragile X syndrome (FXS), a genetic disorder related to autism and intellectual disability, shows that activation of the cerebellum mitigates aberrant responses in sensory processing areas of the brain and improves neurodevelopmental behaviors. The findings, published by UT Southwestern Medical Center researchers in Cell Reports, could offer an opportunity for developing new therapies for neurocognitive disorders.
Glioblastoma, an incurable brain cancer, is characterized by cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons.
Certa manhã, bem cedo, enquanto examinava uma paciente adormecida no Centro de Medicina do Sono, o Dr. Erik St. Louis percebeu algo peculiar. A paciente, uma mulher na faixa dos 60 anos, começou a correr debaixo dos lençóis.
Una mañana temprano, mientras revisaba a una paciente dormida en el Centro de Medicina del Sueño, el Dr. Erik St. Louis observó algo particular. La paciente, una mujer de unos 60 años, había empezado a correr debajo de las sábanas. A media que sus párpados se agitaban, las piernas se pusieron en marcha, lentamente al principio, pero luego aceleraron rápidamente el paso, lo que la impulsó a lo largo de un camino que solo ella podía ver. Después de correr durante aproximadamente 30 segundos, se detuvo bruscamente y abrió los ojos. No era el comportamiento que el Dr. St. Louis esperaba de una persona con apnea del sueño.
مدينة روتشستر، ولاية مينيسوتا— يومًا ما في الصباح الباكر، أثناء فحص حالة نائمة في مركز طب النوم، لاحظ الدكتور إريك سانت لويس أمرًا غريبًا. حيث بدأت الحالة، وهي مريضة في أوائل الستينات من عمرها، تركض تحت غطاء سريرها. حيث بدأت ساقاها تنطلقان ببطء في البداية ثم أخذت تزيد سرعتها لتندفع في طريق لا يراه أحد غيرها، وكان جفناها يرتعشان في نفس الوقت. وبعد الركض لمدة حوالي 30 ثانية، توقفت فجأة وفتحت عينيها. ولم يتوقع الدكتور سانت لويس أن يصدر مثل هذا التصرف من مريض انقطاع النفس النومي.
Among the accomplishments of this year’s awardees are discoveries related to the role of altered pharmacokinetics in non-alcoholic fatty liver disease, the mechanisms of Parkinson’s disease neurodegeneration, the risk of COVID-19 to smokers and vapers, and the role of the microbiome in pregnancy and early developmental programming.
Researchers at the University of California San Diego have developed a neural implant that provides information about activity deep inside the brain while sitting on its surface.
Using advanced research techniques, Rutgers Heath–led scientists have shed light on how chronic fatigue syndrome and fibromyalgia are related, paving the way to even bigger breakthroughs.
Black people consistently had a higher rate of stroke than white people over a recent 22-year period, according to a study published in the January 10, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
New research led by the University of Bristol has explored the neuropsychological effects of rapid-acting antidepressants, including ketamine, scopolamine and psilocybin, and found that all three of these drugs can modulate affective biases associated with learning and memory.
Rice University scientists have developed a noninvasive way to monitor gene expression dynamics in the brain, making it easier to investigate brain development, cognitive function and neurological diseases, according to a study published in Nature Biotechnology.
Researchers at Dana-Farber Cancer Institute and the University of Trento, Italy, have developed a blood test, described in Cancer Discovery, that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma.
Leslie B. Vosshall, PhD, the Robin Chemers Neustein Professor of Neurogenetics and Behavior at The Rockefeller University, will receive the Perl-UNC Neuroscience Prize for her work on receptors that drive host-seeking behavior in the mosquito.