Feature Channels: Parkinson’s Disease

• share
• favorite_border

Parkinson’s Disease develops if a certain anti-viral receptor and its protein in the brain, called the interferon-beta pathway, is not functioning correctly.

• share
• favorite_border

More than 10 million people worldwide have Parkinson’s disease, which is progressively debilitating and, at present, incurable. Now, Texas A&M AgriLife researchers have found a new way to study the disorder’s progression on a molecular level. The team has also obtained new clues toward a treatment.

• share
• favorite_border

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

• share
• favorite_border

In a study of rodents, scientists at the Icahn School of Medicine at Mount Sinai discovered that a part of the brain traditionally thought to control typing the old habits may also play a critical role in learning the new actions. The results, published on August 25th in Nature Communications, suggest that this process involves a delicate balance in the activity of two neighboring neural circuits: one dedicated to new actions and the other to old habits

• share
• favorite_border

• share
• favorite_border

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals—and how they can be potentially targeted by new therapies.

• share
• favorite_border

Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.

• share
• favorite_border

The use of artificial intelligence and machine learning enable new insights to help diagnose illness, suggest specific courses of treatment and follow patient’s progress

• share
• favorite_border

NEWS STORIES IN THIS ISSUE: -Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction -Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia -Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium -Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis -Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development -COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID

• share
• favorite_border

Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson’s disease in mouse studies.

• share
• favorite_border

Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies.

• share
• favorite_border

Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

• share
• favorite_border

A new study published in Brain Sciences today, shows patients with mild-to-moderate Parkinson's disease (PD) can slow the progress of the disease by participating in dance training with music for one-and-a-quarter hours per week.

• share
• favorite_border

A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs with therapeutic potential.

• share
• favorite_border

• share
• favorite_border

Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues.

• share
• favorite_border

A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

• share
• favorite_border

DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.

• share
• favorite_border

A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.

• share
• favorite_border

COLUMBUS, Ohio – The team of neurologists and neurosurgeons at The Ohio State University Wexner Medical Center and its Neurological Institute are among the first in the nation to implant a new deep-brain stimulation (DBS) device that will help improve the quality of life of patients with Parkinson’s disease.

• share
• favorite_border

GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.

• share
• favorite_border

Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that compared to before deep brain stimulation, study participants continued to experience significant improvement in motor symptoms, which are symptoms that affect movement, as well as a reduction in medications 15 years later.

• share
• favorite_border

• share
• favorite_border

A team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.

• share
• favorite_border

Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue.

• share
• favorite_border

A rare mutation that causes Parkinson's disease-like symptoms interrupts the flow of dopamine in the brain, suggests a study in fruit flies published today in eLife.

• share
• favorite_border

ACSM and the Parkinson’s Foundation released new exercise recommendations to provide safe and effective guidance on physical activity to people with Parkinson’s and to certified exercise professionals working with them.

• share
• favorite_border

A reason for these findings could be due to the fact that Parkinson's patients often also have many risk factors for a severe course of Covid-19.

• share
• favorite_border

For the first time, Cornell University researchers have developed a technique for studying the neuroscience of motor control in mice ¬– by focusing on a mouse’s tongue when it licks a water spout.

• share
• favorite_border

Parkinson’s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins may form harmful aggregates, or groupings, that are known to contribute to the development of the disease.

• share
• favorite_border

VGLUT – a glutamate transporter on the membrane of vesicles that carry dopamine – is key to regulating sex differences in the brain’s vulnerability to age-related neuron loss.

• share
• favorite_border

As part of a five-year, $2 million NSF project, Georgia Tech researchers uncover new methods for using sound and vibration to treat and diagnose brain diseases. The research could eliminate reliance on MRIs, paving the way for less costly and simpler systems that could serve a wider population.

• share
• favorite_border

New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.