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Newswise: Tip Sheet: Recent Research on How DNA is Read and Copied

Article ID: 713016

Tip Sheet: Recent Research on How DNA is Read and Copied

Johns Hopkins Medicine

Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. Newly published research by Cynthia Wolberger, Ph.D., and James Berger, Ph.D., whose labs sit side by side, takes a closer look at how the puzzle pieces of DNA machinery fit together.

Released:
21-May-2019 8:00 AM EDT
Newswise: Scientists use molecular tethers and chemical 'light sabers' to construct platforms for tissue engineering

Article ID: 713224

Scientists use molecular tethers and chemical 'light sabers' to construct platforms for tissue engineering

University of Washington

University of Washington researchers developed a strategy to keep proteins intact and functional in synthetic biomaterials for tissue engineering. Their approach modifies proteins at a specific point so that they can be chemically tethered to scaffolds using light.

Released:
21-May-2019 4:05 AM EDT
Newswise: Dangerous pathogens use this sophisticated machinery to infect hosts

Article ID: 713196

Dangerous pathogens use this sophisticated machinery to infect hosts

California Institute of Technology

Gastric cancer, Q fever, Legionnaires' disease, whooping cough--though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.

Released:
20-May-2019 2:05 PM EDT
Newswise: June’s SLAS Technology Special Collection on Sample Management Now Available

Article ID: 713200

June’s SLAS Technology Special Collection on Sample Management Now Available

SLAS (Society for Laboratory Automation and Screening)

The June issue of SLAS Technology features the article, “Next Generation Compound Delivery to Support Miniaturized Biology,” which focuses on the challenges of changing the established screening paradigm to support the needs of modern drug discovery.

Released:
20-May-2019 2:05 PM EDT
Newswise: Zebrafish Help Researchers Explore Alternatives to Bone Marrow Donation

Article ID: 713169

Zebrafish Help Researchers Explore Alternatives to Bone Marrow Donation

University of California San Diego Health

UC San Diego researchers discover new role for epidermal growth factor receptor in blood stem cell development, a crucial key to being able to generate them in the laboratory, and circumvent the need for bone marrow donation.

Released:
20-May-2019 12:05 PM EDT
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Article ID: 713158

Key Drug Target Shown Assembling in Real-Time

Case Western Reserve University

Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout the body—but a recent study shows what happens next. In results published in Cell, researchers outline the timeline of events, including precisely when and how different parts of a GPCR interacts with its G protein signaling partners. The findings provide new insights into the fundamental mechanisms of drug-induced signaling in cells, including ways to identify the most critical portions of GPCRs for targeting development of novel therapeutics.

Released:
20-May-2019 11:05 AM EDT
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  • Embargo expired:
    20-May-2019 11:00 AM EDT

Article ID: 713010

Bolstering Biopsies: Testing Individual Cells to Guide Treatment

Albert Einstein College of Medicine

In research that could make biopsies more useful for many diseases, scientists have used a powerful new tool to zero in on individual cells in a patient’s diseased organ and reveal the cells’ underlying glitches in gene expression—information that may allow for more precise and effective treatment. The findings, by scientists at Albert Einstein College of Medicine, Montefiore Health System, and other medical institutions, are published online today in Nature Immunology.

Released:
16-May-2019 12:35 PM EDT
Newswise: New method simplifies the search for protein receptor complexes, speeding drug development
  • Embargo expired:
    20-May-2019 11:00 AM EDT

Article ID: 713024

New method simplifies the search for protein receptor complexes, speeding drug development

University of Wisconsin-Milwaukee

A new method of assessing the actions of medicines by matching them to their unique protein receptors has the potential to greatly accelerate drug development and diminish the number of drug trials that fail during clinical trials.

Released:
16-May-2019 12:05 PM EDT
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Article ID: 713153

Boston Doctors Honored for Pediatric Cancer Teamwork

American Academy of Dermatology

The American Academy of Dermatology has honored oncologist Jennifer Whangbo, MD, PhD, and dermatologist Jennifer Huang, MD, FAAD, as Patient Care Heroes for their collaboration in caring for pediatric stem cell transplant patients.

Released:
20-May-2019 10:30 AM EDT

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